Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Endothelial_Large_Small_Impute.gct |
| Phenotype | class1 |
| GeneSet | s2.stanford.gmt#CR_IMMUNE_FUNCTION |
| Enrichment Score (ES) | -0.517768 |
| Normalized Enrichment Score (NES) | -1.6821108 |
| Nominal p-value | 0.0077669905 |
| FDR q-value | 0.8329054 |
| FWER p-Value | 0.665 |
| PROBE | DESCRIPTION | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IMAGE:755054 | IL18R1 || Interleukin 18 receptor 1 || Hs.469521 || AA482489 || putative transmembrane receptor IL-1Rrp || 8809 || 114103 | IL18R1 StanfordSource, GeneCards | interleukin 18 receptor 1 | 135 | 0.866 | 0.0357 | No |
| 2 | IMAGE:358549 | KIAA1166 || KIAA1166 || Hs.28249 || W96149 || || 55906 || 114625 | HCA127 StanfordSource, GeneCards | hepatocellular carcinoma-associated antigen 127 | 269 | 0.777 | 0.0671 | No |
| 3 | IMAGE:417018 | CD14 || CD14 antigen || Hs.163867 || W87269 || || 929 || 103127 | CD14 StanfordSource, GeneCards | CD14 antigen | 2767 | 0.346 | -0.0502 | No |
| 4 | IMAGE:125134 | CD48 || CD48 antigen (B-cell membrane protein) || Hs.243564 || R05415 || CD48=BLAST-1 || 962 || 118132 | CD48 StanfordSource, GeneCards | CD48 antigen (B-cell membrane protein)CD48 antigen (B-cell membrane protein) | 2817 | 0.342 | -0.0359 | No |
| 5 | IMAGE:739183 | || || || AA421296 || CD68 || || 111860 | CD68 StanfordSource, GeneCards | CD68 antigen | 3495 | 0.286 | -0.0581 | No |
| 6 | IMAGE:789314 | "CD1D || CD1D antigen, d polypeptide || Hs.1799 || AA451684 || || 912 || 103193" | CD1D StanfordSource, GeneCards | CD1D antigen, d polypeptide | 3541 | 0.282 | -0.0466 | No |
| 7 | IMAGE:727251 | CD9 || CD9 antigen (p24) || Hs.114286 || AA412053 || CD9 || 928 || 103549 | CD9 StanfordSource, GeneCards | CD9 antigen (p24) | 3903 | 0.253 | -0.0535 | No |
| 8 | IMAGE:814841 | "FCGR2B || Fc fragment of IgG, low affinity IIb, receptor (CD32) || Hs.492655 || AA459439 || Low-affinity IgG Fc receptor II-B and C isoforms (multiple o || 2213 || 161168" | FCGR2B StanfordSource, GeneCards | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | 4199 | 0.232 | -0.0578 | No |
| 9 | IMAGE:2316397 | "MAGED2 || Melanoma antigen family D, 2 || Hs.522665 || AI684984 || || 10916 || 319994" | MAGED2 StanfordSource, GeneCards | melanoma antigen, family D, 2 | 4470 | 0.213 | -0.0618 | No |
| 10 | IMAGE:704459 | "CD69 || CD69 antigen (p60, early T-cell activation antigen) || Hs.208854 || AA279755 || CD69=early activation antigen || 969 || 104599" | CD69 StanfordSource, GeneCards | CD69 antigen (p60, early T-cell activation antigen) | 4741 | 0.192 | -0.0668 | No |
| 11 | IMAGE:513077 | "CD47 || **CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || AA062638 || || 961 || 101681" | CD47,NQO1 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer)NAD(P)H dehydrogenase, quinone 1 | 5630 | 0.133 | -0.1080 | No |
| 12 | IMAGE:1917430 | CD33 || CD33 antigen (gp67) || Hs.83731 || AI344474 || || 945 || 307319 | CD33 StanfordSource, GeneCards | CD33 antigen (gp67) | 6348 | 0.088 | -0.1422 | No |
| 13 | IMAGE:154185 | CD68 || CD68 antigen || Hs.246381 || R51936 || || 968 || 121231 | CD68 StanfordSource, GeneCards | CD68 antigen | 6416 | 0.084 | -0.1417 | No |
| 14 | IMAGE:289606 | IL15 || Interleukin 15 || Hs.311958 || N59270 || IL-15 || 3600 || 111123 | IL15 StanfordSource, GeneCards | interleukin 15 | 7366 | 0.032 | -0.1912 | No |
| 15 | IMAGE:208001 | "CD59 || CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) || Hs.278573 || H60548 || CD59=LY-6-like protein regulating complement membrane attack || 966 || 118079" | CD59 StanfordSource, GeneCards | CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) | 7501 | 0.024 | -0.1972 | No |
| 16 | IMAGE:214236 | CD68 || CD68 antigen || Hs.246381 || H77636 || CD68 || 968 || 161020 | CD68 StanfordSource, GeneCards | CD68 antigen | 8291 | -0.019 | -0.2388 | No |
| 17 | IMAGE:771258 | "CD8A || CD8 antigen, alpha polypeptide (p32) || Hs.85258 || AA443584 || CD8 alpha chain || 925 || 110814" | CD8A StanfordSource, GeneCards | CD8 antigen, alpha polypeptide (p32) | 8698 | -0.039 | -0.2587 | No |
| 18 | IMAGE:490368 | "CD58 || CD58 antigen, (lymphocyte function-associated antigen 3) || Hs.34341 || AA136271 || CD58=LFA-3 || 965 || 109967" | CD58 StanfordSource, GeneCards | CD58 antigen, (lymphocyte function-associated antigen 3) | 10283 | -0.119 | -0.3380 | No |
| 19 | IMAGE:741885 | TFE3 || Transcription factor binding to IGHM enhancer 3 || Hs.274184 || AA401326 || || 7030 || 115742 | TFE3 StanfordSource, GeneCards | transcription factor binding to IGHM enhancer 3 | 10537 | -0.133 | -0.3451 | No |
| 20 | IMAGE:824384 | CD37 || CD37 antigen || Hs.166556 || AA489700 || || 951 || 310869 | CD37 StanfordSource, GeneCards | CD37 antigen | 12609 | -0.247 | -0.4444 | No |
| 21 | IMAGE:31839 | IL16 || Interleukin 16 (lymphocyte chemoattractant factor) || Hs.459095 || R41836 || || 3603 || 309932 | IL16 StanfordSource, GeneCards | interleukin 16 (lymphocyte chemoattractant factor) | 12794 | -0.259 | -0.4415 | No |
| 22 | IMAGE:47900 | IFNGR1 || Interferon gamma receptor 1 || Hs.520414 || H11482 || interferon-gamma receptor alpha chain || 3459 || 114960 | IFNGR1 StanfordSource, GeneCards | interferon gamma receptor 1 | 12944 | -0.269 | -0.4361 | No |
| 23 | IMAGE:504226 | CD53 || CD53 antigen || Hs.443057 || AA132090 || CD53 || 963 || 102472 | CD53 StanfordSource, GeneCards | CD53 antigen | 13150 | -0.280 | -0.4333 | No |
| 24 | IMAGE:435434 | CD14 || CD14 antigen || Hs.163867 || AA701476 || || 929 || 111061 | CD14 StanfordSource, GeneCards | CD14 antigen | 13509 | -0.303 | -0.4375 | No |
| 25 | IMAGE:813552 | "CD47 || CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || AA455447 || CD47 antigen=Rh-related antigen= integrin-associated signal || 961 || 117841" | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 14813 | -0.387 | -0.4885 | No |
| 26 | IMAGE:2064497 | NKTR || Natural killer-tumor recognition sequence || Hs.529509 || AI382982 || || 4820 || 314474 | NKTR StanfordSource, GeneCards | natural killer-tumor recognition sequence | 15357 | -0.427 | -0.4966 | Yes |
| 27 | IMAGE:770858 | CD34 || CD34 antigen || Hs.374990 || AA434387 || CD34 || 947 || 102058 | CD34 StanfordSource, GeneCards | CD34 antigen | 15386 | -0.428 | -0.4769 | Yes |
| 28 | IMAGE:290724 | MICA || MHC class I polypeptide-related sequence A || Hs.549053 || N71782 || mic-A=MHC class I chain-related protein A || 4276 || 112649 | MICA StanfordSource, GeneCards | MHC class I polypeptide-related sequence A | 15464 | -0.434 | -0.4595 | Yes |
| 29 | IMAGE:121265 | "IFNAR1 || Interferon (alpha, beta and omega) receptor 1 || Hs.529400 || T96831 || Interferon alpha receptor=HuIFN-alpha-Rec=IFNAR=interferon a || 3454 || 184548" | IFNAR1 StanfordSource, GeneCards | interferon (alpha, beta and omega) receptor 1 | 15910 | -0.471 | -0.4601 | Yes |
| 30 | IMAGE:795827 | TESK1 || Testis-specific kinase 1 || Hs.79358 || AA460580 || TESK1=protein kinase specifically expressed in testicular ge || 7016 || 119603 | TESK1,CD72 StanfordSource, GeneCards | CD72 antigentestis-specific kinase 1 | 15911 | -0.471 | -0.4368 | Yes |
| 31 | IMAGE:78041 | "IL6ST || Interleukin 6 signal transducer (gp130, oncostatin M receptor) || Hs.532082 || T60500 || || 3572 || 120873" | IL6ST StanfordSource, GeneCards | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 16737 | -0.548 | -0.4540 | Yes |
| 32 | IMAGE:213502 | CD53 || CD53 antigen || Hs.443057 || H70124 || CD53 || 963 || 116889 | CD53 StanfordSource, GeneCards | CD53 antigen | 16958 | -0.575 | -0.4374 | Yes |
| 33 | IMAGE:149895 | "CD47 || CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || H00660 || || 961 || 113762" | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 17012 | -0.580 | -0.4115 | Yes |
| 34 | IMAGE:810142 | "HLA-C || Major histocompatibility complex, class I, C || Hs.534125 || AA464246 || MHC Class I=HLA-C4 || 3107 || 113661" | HLA-C StanfordSource, GeneCards | major histocompatibility complex, class I, C | 17150 | -0.598 | -0.3892 | Yes |
| 35 | IMAGE:712460 | NKTR || Natural killer-tumor recognition sequence || Hs.529509 || AA281731 || cathepsin B || 4820 || 186324 | NKTR StanfordSource, GeneCards | natural killer-tumor recognition sequence | 17346 | -0.628 | -0.3685 | Yes |
| 36 | IMAGE:811819 | "CD47 || CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || AA463483 || || 961 || 98397" | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 17454 | -0.646 | -0.3422 | Yes |
| 37 | IMAGE:2514829 | "IL6ST || Interleukin 6 signal transducer (gp130, oncostatin M receptor) || Hs.532082 || AI968672 || || 3572 || 330463" | IL6ST StanfordSource, GeneCards | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 17600 | -0.670 | -0.3168 | Yes |
| 38 | IMAGE:704420 | NKTR || Natural killer-tumor recognition sequence || Hs.529509 || AA279666 || NK-tumor recognition protein=cyclophilin-related protein || 4820 || 186314 | NKTR StanfordSource, GeneCards | natural killer-tumor recognition sequence | 17727 | -0.693 | -0.2892 | Yes |
| 39 | IMAGE:138369 | "FCGR2B || Fc fragment of IgG, low affinity IIb, receptor (CD32) || Hs.492655 || R68106 || Low-affinity IgG Fc receptor II-B and C isoforms (multiple o || 2213 || 102370" | FCGR2B StanfordSource, GeneCards | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | 17731 | -0.694 | -0.2550 | Yes |
| 40 | IMAGE:213635 | CD34 || CD34 antigen || Hs.374990 || H72113 || CD34 || 947 || 105957 | CD34 StanfordSource, GeneCards | CD34 antigen | 17927 | -0.736 | -0.2290 | Yes |
| 41 | IMAGE:782812 | "IFNAR1 || Interferon (alpha, beta and omega) receptor 1 || Hs.529400 || AA448251 || || 3454 || 119267" | IFNAR1 StanfordSource, GeneCards | interferon (alpha, beta and omega) receptor 1 | 17929 | -0.737 | -0.1925 | Yes |
| 42 | IMAGE:2018581 | "IL6ST || Interleukin 6 signal transducer (gp130, oncostatin M receptor) || Hs.532082 || AI360116 || || 3572 || 310822" | IL6ST StanfordSource, GeneCards | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 18026 | -0.757 | -0.1602 | Yes |
| 43 | IMAGE:753743 | "|| Transcribed locus, moderately similar to NP_002175.2 interleukin 6 signal transducer isoform 1 precursor; membrane glycoprotein gp130; oncostatin M receptor; CD130 antigen; interleukin receptor beta c || Hs.318938 || AA406546 || || || 116038" | IL6ST StanfordSource, GeneCards | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 18300 | -0.849 | -0.1328 | Yes |
| 44 | IMAGE:197056 | "CD47 || CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || R92801 || || 961 || 103168" | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 18388 | -0.889 | -0.0934 | Yes |
| 45 | IMAGE:711993 | IFNGR1 || Interferon gamma receptor 1 || Hs.520414 || AA281497 || interferon-gamma receptor alpha chain || 3459 || 186427 | IFNGR1 StanfordSource, GeneCards | interferon gamma receptor 1 | 18528 | -1.022 | -0.0502 | Yes |
| 46 | IMAGE:784198 | "CD47 || CD47 antigen (Rh-related antigen, integrin-associated signal transducer) || Hs.446414 || AA446657 || || 961 || 318029" | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 18576 | -1.110 | 0.0023 | Yes |
