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Gene set: DRUG_RESISTANCE_AND_METABOLISM (C2:EXCU:0020)
Standard nameDRUG_RESISTANCE_AND_METABOLISM
Systematic nameC2:EXCU:0020
Brief descriptionGenes implicated in drug resistamce and metabolism
CategoryC2: Curated
Sub-categoryEXCU: Expert curation
Full description or Abstract
na
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman
Contributed byBroad Institute
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

100 genes, 100 accessions (Toggle view)

GeneTitleLinks
GSTP1glutathione S-transferase piSource|GeneCards
EPHX1epoxide hydrolase 1, microsomal (xenobiotic)Source|GeneCards
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 6Source|GeneCards
ABCC1ATP-binding cassette, sub-family C (CFTR/MRP), member 1Source|GeneCards
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1Source|GeneCards
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase)Source|GeneCards
SOD1superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))Source|GeneCards
TOP2Btopoisomerase (DNA) II beta 180kDaSource|GeneCards
TPMTthiopurine S-methyltransferaseSource|GeneCards
TOP2Atopoisomerase (DNA) II alpha 170kDaSource|GeneCards
AHRaryl hydrocarbon receptorSource|GeneCards
TYMSthymidylate synthetaseSource|GeneCards
BRCA1breast cancer 1, early onsetSource|GeneCards
RXRGretinoid X receptor, gammaSource|GeneCards
MYCV-myc myelocytomatosis viral oncogene homolog (avian)Source|GeneCards
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)Source|GeneCards
CDK2cyclin-dependent kinase 2Source|GeneCards
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 5Source|GeneCards
TOP1topoisomerase (DNA) ISource|GeneCards
CCNE1cyclin E1Source|GeneCards
ABCC5ATP-binding cassette, sub-family C (CFTR/MRP), member 5Source|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
DHFRdihydrofolate reductaseSource|GeneCards
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)Source|GeneCards
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)Source|GeneCards
ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1Source|GeneCards
BCL2L1BCL2-like 1Source|GeneCards
TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, activator of NFKBSource|GeneCards
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)Source|GeneCards
EPHX2epoxide hydrolase 2, cytoplasmicSource|GeneCards
CRABP1Cellular retinoic acid binding protein 1Source|GeneCards
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)Source|GeneCards
GSTM1glutathione S-transferase M1Source|GeneCards
CCND1cyclin D1 (PRAD1: parathyroid adenomatosis 1)Source|GeneCards
GSK3Aglycogen synthase kinase 3 alphaSource|GeneCards
CDKN2Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)Source|GeneCards
PPIApeptidylprolyl isomerase A (cyclophilin A)Source|GeneCards
RARBretinoic acid receptor, betaSource|GeneCards
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)Source|GeneCards
MGMTO-6-methylguanine-DNA methyltransferaseSource|GeneCards
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8Source|GeneCards
RXRBretinoid X receptor, betaSource|GeneCards
RARGretinoic acid receptor, gammaSource|GeneCards
RB1retinoblastoma 1 (including osteosarcoma)Source|GeneCards
SRD5A2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)Source|GeneCards
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9Source|GeneCards
PPARAperoxisome proliferative activated receptor, alphaSource|GeneCards
ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 3Source|GeneCards
IGF1Rinsulin-like growth factor 1 receptorSource|GeneCards
IGF2Rinsulin-like growth factor 2 receptorSource|GeneCards
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2Source|GeneCards
RARAretinoic acid receptor, alphaSource|GeneCards
XPAxeroderma pigmentosum, complementation group ASource|GeneCards
METmet proto-oncogene (hepatocyte growth factor receptor)Source|GeneCards
PPARGperoxisome proliferative activated receptor, gammaSource|GeneCards
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, betaSource|GeneCards
CRR9cisplatin resistance related protein CRR9pSource|GeneCards
BCL2B-cell CLL/lymphoma 2Source|GeneCards
XPCxeroderma pigmentosum, complementation group CSource|GeneCards
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)Source|GeneCards
ABCC6ATP-binding cassette, sub-family C (CFTR/MRP), member 6Source|GeneCards
PPARDperoxisome proliferative activated receptor, deltaSource|GeneCards
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 19Source|GeneCards
HIF1Ahypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Source|GeneCards
BLMHbleomycin hydrolaseSource|GeneCards
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)Source|GeneCards
RELBv-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)Source|GeneCards
CYP2D6cytochrome P450, family 2, subfamily D, polypeptide 6Source|GeneCards
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
ESR1estrogen receptor 1Source|GeneCards
EGFRepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Source|GeneCards
COMTcatechol-O-methyltransferaseSource|GeneCards
ESR2estrogen receptor 2 (ER beta)Source|GeneCards
RPL13Aribosomal protein L13aSource|GeneCards
FGF2fibroblast growth factor 2 (basic)Source|GeneCards
BRCA2breast cancer 2, early onsetSource|GeneCards
MSH3mutS homolog 3 (E. coli)Source|GeneCards
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4Source|GeneCards
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2Source|GeneCards
BAXBCL2-associated X proteinSource|GeneCards
MVPmajor vault proteinSource|GeneCards
NQO1NAD(P)H dehydrogenase, quinone 1Source|GeneCards
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2Source|GeneCards
APCadenomatosis polyposis coliSource|GeneCards
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)Source|GeneCards
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 1Source|GeneCards
RXRAretinoid X receptor, alphaSource|GeneCards
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilonSource|GeneCards
AP1S1adaptor-related protein complex 1, sigma 1 subunitSource|GeneCards
ARandrogen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)Source|GeneCards
ARNTaryl hydrocarbon receptor nuclear translocatorSource|GeneCards
GAPDglyceraldehyde-3-phosphate dehydrogenaseSource|GeneCards
CDK4cyclin-dependent kinase 4Source|GeneCards
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)Source|GeneCards
FOSv-fos FBJ murine osteosarcoma viral oncogene homologSource|GeneCards
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)Source|GeneCards
ELK1ELK1, member of ETS oncogene familySource|GeneCards
ACTBactin, betaSource|GeneCards


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