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Gene set: ST_INTEGRIN_SIGNALING_PATHWAY (C2:PATH:0269)
Standard nameST_INTEGRIN_SIGNALING_PATHWAY
Systematic nameC2:PATH:0269
Brief descriptionIntegrins are transmembrane receptors that mediate cell growth, survival, and migration by binding to ligands in the extracellular matrix.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://stke.sciencemag.org/cgi/cm/stkecm;CMP_6880
Keywords & MeSH headingsna
OrganismGeneric
Contributed bySignalling Transduction KE
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

82 genes, 82 accessions (Toggle view)

GeneTitleLinks
ANGPTL2angiopoietin-like 2Source|GeneCards
PAK3p21 (CDKN1A)-activated kinase 3Source|GeneCards
GRLF1glucocorticoid receptor DNA binding factor 1Source|GeneCards
ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)Source|GeneCards
ILKintegrin-linked kinaseSource|GeneCards
MRASmuscle RAS oncogene homologSource|GeneCards
PAK6p21(CDKN1A)-activated kinase 6Source|GeneCards
MAP3K11mitogen-activated protein kinase kinase kinase 11Source|GeneCards
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)Source|GeneCards
TERF2IPtelomeric repeat binding factor 2, interacting proteinSource|GeneCards
ACTR2ARP2 actin-related protein 2 homolog (yeast)Source|GeneCards
MAP2K7mitogen-activated protein kinase kinase 7Source|GeneCards
ITGA6integrin, alpha 6Source|GeneCards
EPHB2EphB2Source|GeneCards
ABL1v-abl Abelson murine leukemia viral oncogene homolog 1Source|GeneCards
AKT2v-akt murine thymoma viral oncogene homolog 2Source|GeneCards
CDC42cell division cycle 42 (GTP binding protein, 25kDa)Source|GeneCards
PTK2PTK2 protein tyrosine kinase 2Source|GeneCards
ITGA10integrin, alpha 10Source|GeneCards
MAPK8IP3mitogen-activated protein kinase 8 interacting protein 3Source|GeneCards
GRB2growth factor receptor-bound protein 2Source|GeneCards
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)Source|GeneCards
ROCK1Rho-associated, coiled-coil containing protein kinase 1Source|GeneCards
CAV1caveolin 1, caveolae protein, 22kDaSource|GeneCards
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptideSource|GeneCards
PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific)Source|GeneCards
PKLRpyruvate kinase, liver and RBCSource|GeneCards
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)Source|GeneCards
MAPK10mitogen-activated protein kinase 10Source|GeneCards
TLN1talin 1Source|GeneCards
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)Source|GeneCards
ITGA1integrin, alpha 1Source|GeneCards
FYNFYN oncogene related to SRC, FGR, YESSource|GeneCards
P4HBein p55)Source|GeneCards
MAPK8mitogen-activated protein kinase 8Source|GeneCards
PAK4p21(CDKN1A)-activated kinase 4Source|GeneCards
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7Source|GeneCards
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)Source|GeneCards
ITGB3BPintegrin beta 3 binding protein (beta3-endonexin)Source|GeneCards
RALAv-ral simian leukemia viral oncogene homolog A (ras related)Source|GeneCards
ITGA8integrin, alpha 8Source|GeneCards
SOS1son of sevenless homolog 1 (Drosophila)Source|GeneCards
BCAR1breast cancer anti-estrogen resistance 1Source|GeneCards
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)Source|GeneCards
RHORhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)Source|GeneCards
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2Source|GeneCards
AKT1v-akt murine thymoma viral oncogene homolog 1Source|GeneCards
ACTN1actinin, alpha 1Source|GeneCards
SOS2son of sevenless homolog 2 (Drosophila)Source|GeneCards
MYLKmyosin, light polypeptide kinaseSource|GeneCards
AKT3v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)Source|GeneCards
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1Source|GeneCards
PLCG1phospholipase C, gamma 1 (formerly subtype 148)Source|GeneCards
ITGA7integrin, alpha 7Source|GeneCards
PAK1p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)Source|GeneCards
PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptideSource|GeneCards
CSE1LCSE1 chromosome segregation 1-like (yeast)Source|GeneCards
SHC1SHC (Src homology 2 domain containing) transforming protein 1Source|GeneCards
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6Source|GeneCards
ITGA11integrin, alpha 11Source|GeneCards
ACTR3ARP3 actin-related protein 3 homolog (yeast)Source|GeneCards
DDEF1development and differentiation enhancing factor 1Source|GeneCards
RAF1v-raf-1 murine leukemia viral oncogene homolog 1Source|GeneCards
MAP2K4mitogen-activated protein kinase kinase 4Source|GeneCards
BRAFv-raf murine sarcoma viral oncogene homolog B1Source|GeneCards
MYLK2myosin light chain kinase 2, skeletal muscleSource|GeneCards
PAK7p21(CDKN1A)-activated kinase 7Source|GeneCards
MAPK9mitogen-activated protein kinase 9Source|GeneCards
ZYXzyxinSource|GeneCards
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)Source|GeneCards
ROCK2Rho-associated, coiled-coil containing protein kinase 2Source|GeneCards
DOCK1dedicator of cytokinesis 1Source|GeneCards
VASPvasodilator-stimulated phosphoproteinSource|GeneCards
GRB7growth factor receptor-bound protein 7Source|GeneCards
PAK2p21 (CDKN1A)-activated kinase 2Source|GeneCards
MAPK1mitogen-activated protein kinase 1Source|GeneCards
TLN2talin 2Source|GeneCards
ITGA9integrin, alpha 9Source|GeneCards
PTENphosphatase and tensin homolog (mutated in multiple advanced cancers 1)Source|GeneCards


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