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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: edg1Pathway (C2:PATH:0073)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>edg1Pathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0073</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>The lipid S1P is an EDG1 ligand promoting chemotaxis via Rac1 and cell survival and proliferation via ERK activation.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_edg1Pathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_edg1Pathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='edg1Pathway.grp'>grp</a>|<a href='edg1Pathway.xml'>xml</a>|<a href='edg1Pathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>26 genes, 26 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>SMPD2</td><td>sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SMPD2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SMPD2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITGB3</td><td>integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITGB3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITGB3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNGT1</td><td>guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNGT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNGT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDGFRA</td><td>platelet-derived growth factor receptor, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDGFRA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDGFRA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKCB1</td><td>protein kinase C, beta 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKCB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKCB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SMPD1</td><td>sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SMPD1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SMPD1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RAC1</td><td>ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK3</td><td>mitogen-activated protein kinase 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT1</td><td>v-akt murine thymoma viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDGFA</td><td>platelet-derived growth factor alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDGFA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDGFA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ADCY1</td><td>adenylate cyclase 1 (brain)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ADCY1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ADCY1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3R1</td><td>phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3R1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3R1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNAI1</td><td>guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNAI1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNAI1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTK2</td><td>PTK2 protein tyrosine kinase 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTK2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTK2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKCA</td><td>protein kinase C, alpha</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKCA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKCA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLCB1</td><td>phospholipase C, beta 1 (phosphoinositide-specific)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLCB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLCB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SPHK1</td><td>sphingosine kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SPHK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SPHK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ASAH1</td><td>N-acylsphingosine amidohydrolase (acid ceramidase) 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ASAH1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ASAH1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3CA</td><td>phosphoinositide-3-kinase, catalytic, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EDG1</td><td>endothelial differentiation, sphingolipid G-protein-coupled receptor, 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EDG1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EDG1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK1</td><td>mitogen-activated protein kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SRC</td><td>v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SRC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SRC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNB1</td><td>guanine nucleotide binding protein (G protein), beta polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNB1' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>ITGAV</td><td>integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITGAV' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITGAV' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr></table></div></td></tr></table></div><br><hr>
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