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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: erkPathway (C2:PATH:0086)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>erkPathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0086</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_erkPathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_erkPathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='erkPathway.grp'>grp</a>|<a href='erkPathway.xml'>xml</a>|<a href='erkPathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>30 genes, 30 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>EGFR</td><td>epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EGFR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EGFR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IGF1R</td><td>insulin-like growth factor 1 receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IGF1R' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IGF1R' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNGT1</td><td>guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNGT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNGT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SOS1</td><td>son of sevenless homolog 1 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SOS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SOS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDGFRA</td><td>platelet-derived growth factor receptor, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDGFRA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDGFRA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK3</td><td>mitogen-activated protein kinase 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITGB1</td><td>integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITGB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITGB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NGFR</td><td>nerve growth factor receptor (TNFR superfamily, member 16)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NGFR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NGFR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTPRR</td><td>protein tyrosine phosphatase, receptor type, R</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTPRR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTPRR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP2K1</td><td>mitogen-activated protein kinase kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP2K1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP2K1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SHC1</td><td>SHC (Src homology 2 domain containing) transforming protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SHC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SHC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>STAT3</td><td>signal transducer and activator of transcription 3 (acute-phase response factor)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=STAT3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?STAT3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MYC</td><td>V-myc myelocytomatosis viral oncogene homolog (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MYC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MYC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RAF1</td><td>v-raf-1 murine leukemia viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAF1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NGFB</td><td>nerve growth factor, beta polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NGFB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NGFB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MKNK1</td><td>MAP kinase-interacting serine/threonine kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MKNK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MKNK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>KLK2</td><td>kallikrein 2, prostatic</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=KLK2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?KLK2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GRB2</td><td>growth factor receptor-bound protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GRB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GRB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HRAS</td><td>v-Ha-ras Harvey rat sarcoma viral oncogene homolog</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HRAS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HRAS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MKNK2</td><td>MAP kinase-interacting serine/threonine kinase 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MKNK2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MKNK2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DPM2</td><td>dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DPM2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DPM2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP2K2</td><td>mitogen-activated protein kinase kinase 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP2K2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP2K2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPS6KA5</td><td>ribosomal protein S6 kinase, 90kDa, polypeptide 5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPS6KA5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPS6KA5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNAS</td><td>GNAS complex locus</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNAS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNAS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SRC</td><td>v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SRC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SRC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP2CA</td><td>protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP2CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP2CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPS6KA1</td><td>ribosomal protein S6 kinase, 90kDa, polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPS6KA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPS6KA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK1</td><td>mitogen-activated protein kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GNB1</td><td>guanine nucleotide binding protein (G protein), beta polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GNB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GNB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ELK1</td><td>ELK1, member of ETS oncogene family</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ELK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ELK1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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