[an error occurred while processing this directive]
Gene set: g1Pathway (C2:PATH:0101)
Standard nameg1Pathway
Systematic nameC2:PATH:0101
Brief descriptionCDK4/6-cyclin D and CDK2-cyclin E phosphorylate Rb, which allows the transcription of genes needed for the G1/S cell cycle transition.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_g1Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

28 genes, 28 accessions (Toggle view)

GeneTitleLinks
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
TGFB2transforming growth factor, beta 2Source|GeneCards
TFDP1transcription factor Dp-1Source|GeneCards
CDK6cyclin-dependent kinase 6Source|GeneCards
CCNA1cyclin A1Source|GeneCards
CCND1cyclin D1 (PRAD1: parathyroid adenomatosis 1)Source|GeneCards
HDAC1histone deacetylase 1Source|GeneCards
SKP2S-phase kinase-associated protein 2 (p45)Source|GeneCards
ABL1v-abl Abelson murine leukemia viral oncogene homolog 1Source|GeneCards
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)Source|GeneCards
GSK3Bglycogen synthase kinase 3 betaSource|GeneCards
E2F1E2F transcription factor 1Source|GeneCards
CDC25Acell division cycle 25ASource|GeneCards
CDK2cyclin-dependent kinase 2Source|GeneCards
TGFB3transforming growth factor, beta 3Source|GeneCards
ATRataxia telangiectasia and Rad3 relatedSource|GeneCards
CCNE1cyclin E1Source|GeneCards
CDC2cell division cycle 2, G1 to S and G2 to MSource|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
DHFRdihydrofolate reductaseSource|GeneCards
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)Source|GeneCards
CDK4cyclin-dependent kinase 4Source|GeneCards
RB1retinoblastoma 1 (including osteosarcoma)Source|GeneCards
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)Source|GeneCards
TGFB1transforming growth factor, beta 1 (Camurati-Engelmann disease)Source|GeneCards
CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)Source|GeneCards


[an error occurred while processing this directive]