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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: igf1mtorPathway (C2:PATH:0122)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>igf1mtorPathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0122</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Growth factor IGF-1 activates AKT, Gsk3-beta, and mTOR to promote muscle hypertrophy.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_igf1mtorPathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_igf1mtorPathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='igf1mtorPathway.grp'>grp</a>|<a href='igf1mtorPathway.xml'>xml</a>|<a href='igf1mtorPathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>20 genes, 20 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>EIF2S1</td><td>eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF2S1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF2S1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IGF1R</td><td>insulin-like growth factor 1 receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IGF1R' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IGF1R' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GSK3B</td><td>glycogen synthase kinase 3 beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GSK3B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GSK3B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDPK1</td><td>3-phosphoinositide dependent protein kinase-1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>INPPL1</td><td>inositol polyphosphate phosphatase-like 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=INPPL1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?INPPL1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDK2</td><td>pyruvate dehydrogenase kinase, isoenzyme 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDK2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDK2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EIF2S2</td><td>eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF2S2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF2S2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT1</td><td>v-akt murine thymoma viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FRAP1</td><td>FK506 binding protein 12-rapamycin associated protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FRAP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FRAP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EIF4E</td><td>eukaryotic translation initiation factor 4E</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF4E' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF4E' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IGF1</td><td>insulin-like growth factor 1 (somatomedin C)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IGF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IGF1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPS6</td><td>ribosomal protein S6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPS6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPS6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3CA</td><td>phosphoinositide-3-kinase, catalytic, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3R1</td><td>phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3R1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3R1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EIF4EBP1</td><td>eukaryotic translation initiation factor 4E binding protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF4EBP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF4EBP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP2CA</td><td>protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP2CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP2CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EIF2S3</td><td>eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF2S3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF2S3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EIF2B5</td><td>eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EIF2B5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EIF2B5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTEN</td><td>phosphatase and tensin homolog (mutated in multiple advanced cancers 1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTEN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTEN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPS6KB1</td><td>ribosomal protein S6 kinase, 70kDa, polypeptide 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPS6KB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPS6KB1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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