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Gene set: mapkPathway (C2:PATH:0153)
Standard namemapkPathway
Systematic nameC2:PATH:0153
Brief descriptionThe mitogen-activated protein (MAP) kinase pathway is a common signaling mechanism and has four main sub-pathways: Erk, JNK/SAPK, p53, and ERK5.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_mapkPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

87 genes, 87 accessions (Toggle view)

GeneTitleLinks
MAPK6mitogen-activated protein kinase 6Source|GeneCards
MAP3K10mitogen-activated protein kinase kinase kinase 10Source|GeneCards
TGFB2transforming growth factor, beta 2Source|GeneCards
MAP3K7mitogen-activated protein kinase kinase kinase 7Source|GeneCards
MAPK14mitogen-activated protein kinase 14Source|GeneCards
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3Source|GeneCards
MAP2K6mitogen-activated protein kinase kinase 6Source|GeneCards
RELAv-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)Source|GeneCards
RPS6KA4ribosomal protein S6 kinase, 90kDa, polypeptide 4Source|GeneCards
ATF2activating transcription factor 2Source|GeneCards
MEF2DMADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)Source|GeneCards
MAPK11mitogen-activated protein kinase 11Source|GeneCards
MAP4K1mitogen-activated protein kinase kinase kinase kinase 1Source|GeneCards
MAP3K13mitogen-activated protein kinase kinase kinase 13Source|GeneCards
MAP3K8mitogen-activated protein kinase kinase kinase 8Source|GeneCards
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2Source|GeneCards
MAP3K11mitogen-activated protein kinase kinase kinase 11Source|GeneCards
TGFBR1transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)Source|GeneCards
MAP2K7mitogen-activated protein kinase kinase 7Source|GeneCards
MYCV-myc myelocytomatosis viral oncogene homolog (avian)Source|GeneCards
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1Source|GeneCards
MEF2BMADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)Source|GeneCards
MAPK13mitogen-activated protein kinase 13Source|GeneCards
TRAF2TNF receptor-associated factor 2Source|GeneCards
MAP3K1mitogen-activated protein kinase kinase kinase 1Source|GeneCards
MKNK1MAP kinase-interacting serine/threonine kinase 1Source|GeneCards
RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 2Source|GeneCards
CHUKconserved helix-loop-helix ubiquitous kinaseSource|GeneCards
GRB2growth factor receptor-bound protein 2Source|GeneCards
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homologSource|GeneCards
MAPK7mitogen-activated protein kinase 7Source|GeneCards
MAP3K14mitogen-activated protein kinase kinase kinase 14Source|GeneCards
MAP4K3mitogen-activated protein kinase kinase kinase kinase 3Source|GeneCards
TGFB3transforming growth factor, beta 3Source|GeneCards
MKNK2MAP kinase-interacting serine/threonine kinase 2Source|GeneCards
MAP3K5mitogen-activated protein kinase kinase kinase 5Source|GeneCards
MAP2K2mitogen-activated protein kinase kinase 2Source|GeneCards
MAPK10mitogen-activated protein kinase 10Source|GeneCards
MEF2AMADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)Source|GeneCards
RPS6KA1ribosomal protein S6 kinase, 90kDa, polypeptide 1Source|GeneCards
DAXXdeath-associated protein 6Source|GeneCards
TGFB1transforming growth factor, beta 1 (Camurati-Engelmann disease)Source|GeneCards
MAPK8mitogen-activated protein kinase 8Source|GeneCards
MAXMAX proteinSource|GeneCards
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaSource|GeneCards
SP1Sp1 transcription factorSource|GeneCards
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)Source|GeneCards
MAP3K3mitogen-activated protein kinase kinase kinase 3Source|GeneCards
MAPK3mitogen-activated protein kinase 3Source|GeneCards
JUNv-jun sarcoma virus 17 oncogene homolog (avian)Source|GeneCards
MAP3K6mitogen-activated protein kinase kinase kinase 6Source|GeneCards
MAP4K5mitogen-activated protein kinase kinase kinase kinase 5Source|GeneCards
MAPK4mitogen-activated protein kinase 4Source|GeneCards
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betaSource|GeneCards
MAP4K4mitogen-activated protein kinase kinase kinase kinase 4Source|GeneCards
PAK1p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)Source|GeneCards
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1Source|GeneCards
CEBPACCAAT/enhancer binding protein (C/EBP), alphaSource|GeneCards
MAP2K1mitogen-activated protein kinase kinase 1Source|GeneCards
SHC1SHC (Src homology 2 domain containing) transforming protein 1Source|GeneCards
MAPKAPK5mitogen-activated protein kinase-activated protein kinase 5Source|GeneCards
RAF1v-raf-1 murine leukemia viral oncogene homolog 1Source|GeneCards
MAP2K4mitogen-activated protein kinase kinase 4Source|GeneCards
TRADDTNFRSF1A-associated via death domainSource|GeneCards
MAP4K2mitogen-activated protein kinase kinase kinase kinase 2Source|GeneCards
MEF2CMADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)Source|GeneCards
MAPK12mitogen-activated protein kinase 12Source|GeneCards
MAP2K3mitogen-activated protein kinase kinase 3Source|GeneCards
BRAFv-raf murine sarcoma viral oncogene homolog B1Source|GeneCards
MAPK9mitogen-activated protein kinase 9Source|GeneCards
MAP3K2mitogen-activated protein kinase kinase kinase 2Source|GeneCards
MAP3K9mitogen-activated protein kinase kinase kinase 9Source|GeneCards
MAPKAPK3mitogen-activated protein kinase-activated protein kinase 3Source|GeneCards
STAT1signal transducer and activator of transcription 1, 91kDaSource|GeneCards
MAP3K4mitogen-activated protein kinase kinase kinase 4Source|GeneCards
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2Source|GeneCards
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)Source|GeneCards
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5Source|GeneCards
MAP3K12mitogen-activated protein kinase kinase kinase 12Source|GeneCards
CREB1cAMP responsive element binding protein 1Source|GeneCards
PAK2p21 (CDKN1A)-activated kinase 2Source|GeneCards
MAPK1mitogen-activated protein kinase 1Source|GeneCards
FOSv-fos FBJ murine osteosarcoma viral oncogene homologSource|GeneCards
MAP2K5mitogen-activated protein kinase kinase 5Source|GeneCards
ELK1ELK1, member of ETS oncogene familySource|GeneCards


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