[an error occurred while processing this directive]
Gene set: nkcellsPathway (C2:PATH:0173)
Standard namenkcellsPathway
Systematic nameC2:PATH:0173
Brief descriptionNatural killer (NK) lymphocytes are inhibited by MHC and activated by surface glycoproteins on tumor or virus-infected cells, which undergo perforin-mediated lysis.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_nkcellsPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

20 genes, 20 accessions (Toggle view)

GeneTitleLinks
LATlinker for activation of T cellsSource|GeneCards
VAV1vav 1 oncogeneSource|GeneCards
KLRD1killer cell lectin-like receptor subfamily D, member 1Source|GeneCards
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)Source|GeneCards
MAPK3mitogen-activated protein kinase 3Source|GeneCards
IL18interleukin 18 (interferon-gamma-inducing factor)Source|GeneCards
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)Source|GeneCards
KLRC4killer cell lectin-like receptor subfamily C, member 4Source|GeneCards
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptideSource|GeneCards
PTPN6protein tyrosine phosphatase, non-receptor type 6Source|GeneCards
KLRC1killer cell lectin-like receptor subfamily C, member 1Source|GeneCards
PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
HLA-Amajor histocompatibility complex, class I, ASource|GeneCards
PTK2BPTK2B protein tyrosine kinase 2 betaSource|GeneCards
PAK1p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)Source|GeneCards
MAP2K1mitogen-activated protein kinase kinase 1Source|GeneCards
KLRC2killer cell lectin-like receptor subfamily C, member 2Source|GeneCards
SYKspleen tyrosine kinaseSource|GeneCards
KLRC3killer cell lectin-like receptor subfamily C, member 3Source|GeneCards
B2Mbeta-2-microglobulinSource|GeneCards


[an error occurred while processing this directive]