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Gene set: p35alzheimersPathway (C2:PATH:0182)
Standard namep35alzheimersPathway
Systematic nameC2:PATH:0182
Brief descriptionp35, a neuron-specific activator of cyclin-dependent kinase 5, is cleaved to p25 in Alzheimer's disease and promotoes hyperphosphorylated tau formation and apoptosis.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_p35alzheimersPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

11 genes, 11 accessions (Toggle view)

GeneTitleLinks
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)Source|GeneCards
MAPTmicrotubule-associated protein tauSource|GeneCards
CAPN1calpain 1, (mu/I) large subunitSource|GeneCards
GSK3Bglycogen synthase kinase 3 betaSource|GeneCards
CAPNS1calpain, small subunit 1Source|GeneCards
CSNK1A1casein kinase 1, alpha 1Source|GeneCards
PPP2CAprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoformSource|GeneCards
CSNK1Dcasein kinase 1, deltaSource|GeneCards
APPamyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)Source|GeneCards
CAPNS2calpain small subunit 2Source|GeneCards
CDK5cyclin-dependent kinase 5Source|GeneCards


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