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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: proteasomePathway (C2:PATH:0204)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>proteasomePathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0204</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Ubiquitinated proteins are targeted for proteolytic degradation by the proteasome, where they are unfolded and degraded to small peptides in an ATP-dependent process.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_proteasomePathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_proteasomePathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='proteasomePathway.grp'>grp</a>|<a href='proteasomePathway.xml'>xml</a>|<a href='proteasomePathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>21 genes, 21 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>PSMB1</td><td>proteasome (prosome, macropain) subunit, beta type, 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMD14</td><td>proteasome (prosome, macropain) 26S subunit, non-ATPase, 14</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMD14' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMD14' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB5</td><td>proteasome (prosome, macropain) subunit, beta type, 5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA4</td><td>proteasome (prosome, macropain) subunit, alpha type, 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPN2</td><td>ribophorin II</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPN2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPN2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMC3</td><td>proteasome (prosome, macropain) 26S subunit, ATPase, 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMC3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMC3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB2</td><td>proteasome (prosome, macropain) subunit, beta type, 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA1</td><td>proteasome (prosome, macropain) subunit, alpha type, 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB7</td><td>proteasome (prosome, macropain) subunit, beta type, 7</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB6</td><td>proteasome (prosome, macropain) subunit, beta type, 6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA5</td><td>proteasome (prosome, macropain) subunit, alpha type, 5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UBE2A</td><td>ubiquitin-conjugating enzyme E2A (RAD6 homolog)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UBE2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UBE2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPN1</td><td>ribophorin I</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA2</td><td>proteasome (prosome, macropain) subunit, alpha type, 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB3</td><td>proteasome (prosome, macropain) subunit, beta type, 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA6</td><td>proteasome (prosome, macropain) subunit, alpha type, 6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UBE3A</td><td>ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UBE3A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UBE3A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA3</td><td>proteasome (prosome, macropain) subunit, alpha type, 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMB4</td><td>proteasome (prosome, macropain) subunit, beta type, 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMB4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMB4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMA7</td><td>proteasome (prosome, macropain) subunit, alpha type, 7</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMA7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMA7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UBE1</td><td>ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UBE1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UBE1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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