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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: tnfr1Pathway (C2:PATH:0301)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>tnfr1Pathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0301</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Tumor necrosis factor alpha binds to its receptor TNFR1 and induces caspase-dependent apoptosis.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_tnfr1Pathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_tnfr1Pathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='tnfr1Pathway.grp'>grp</a>|<a href='tnfr1Pathway.xml'>xml</a>|<a href='tnfr1Pathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>29 genes, 29 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>LMNB2</td><td>lamin B2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LMNB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LMNB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP3K7</td><td>mitogen-activated protein kinase kinase kinase 7</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP3K7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP3K7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF1A</td><td>tumor necrosis factor receptor superfamily, member 1A</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF1A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF1A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ARHGDIB</td><td>Rho GDP dissociation inhibitor (GDI) beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ARHGDIB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ARHGDIB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>JUN</td><td>v-jun sarcoma virus 17 oncogene homolog (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=JUN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?JUN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CRADD</td><td>CASP2 and RIPK1 domain containing adaptor with death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CRADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CRADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP3</td><td>caspase 3, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP3' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>PAK1</td><td>p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PAK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PAK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BAG4</td><td>BCL2-associated athanogene 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BAG4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BAG4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RIPK1</td><td>receptor (TNFRSF)-interacting serine-threonine kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RIPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RIPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP8</td><td>caspase 8, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP8' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LMNA</td><td>lamin A/C</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LMNA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LMNA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNF</td><td>tumor necrosis factor (TNF superfamily, member 2)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKDC</td><td>protein kinase, DNA-activated, catalytic polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKDC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKDC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP2K4</td><td>mitogen-activated protein kinase kinase 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP2K4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP2K4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRAF2</td><td>TNF receptor-associated factor 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRAF2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRAF2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRADD</td><td>TNFRSF1A-associated via death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP3K1</td><td>mitogen-activated protein kinase kinase kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP3K1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP3K1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SPTAN1</td><td>spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SPTAN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SPTAN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FADD</td><td>Fas (TNFRSF6)-associated via death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LMNB1</td><td>lamin B1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LMNB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LMNB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MADD</td><td>MAP-kinase activating death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DFFB</td><td>DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DFFB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DFFB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RB1</td><td>retinoblastoma 1 (including osteosarcoma)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PAK2</td><td>p21 (CDKN1A)-activated kinase 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PAK2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PAK2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP2</td><td>caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DFFA</td><td>DNA fragmentation factor, 45kDa, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DFFA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DFFA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK8</td><td>mitogen-activated protein kinase 8</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK8' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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