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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: HYPOXIA_UP_MANALO (C2:PERT:0102)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>HYPOXIA_UP_MANALO</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PERT:0102</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Genes upregulated in human pulmonary endothelial cells under hypoxic conditions or after exposure to AdCA5, an adenovirus carrying constitutively active hypoxia-inducible factor 1 (HIF-1alpha).</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PERT: Experimental pertuberation</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>Hypoxia-inducible factor 1 (HIF-1) activates transcription of
genes encoding angiogenic growth factors, which are secreted by
hypoxic cells and stimulate endothelial cells, leading to angiogenesis.
To determine whether HIF-1 also mediates cell-autonomous responses
to hypoxia, we have compared gene expression profiles in arterial
endothelial cells cultured under nonhypoxic versus hypoxic conditions
and in nonhypoxic cells infected with adenovirus encoding beta-galactosidase
versus a constitutively active form of HIF-1alpha (AdCA5). There
were 245 gene probes that showed at least 1.5-fold increase in
expression in response to hypoxia and in response to AdCA5; 325
gene probes showed at least 1.5-fold decrease in expression in
response to hypoxia and in response to AdCA5. The largest category
of genes down-regulated by both hypoxia and AdCA5 encoded proteins
involved in cell growth/proliferation. Many genes up-regulated
by both hypoxia and AdCA5 encoded cytokines/growth factors, receptors,
and other signaling proteins. Transcription factors accounted
for the largest group of HIF-1-regulated genes, indicating that
HIF-1 controls a network of transcriptional responses to hypoxia
in endothelial cells. Infection of endothelial cells with AdCA5
under nonhypoxic conditions was sufficient to induce increased
basement membrane invasion and tube formation similar to the responses
induced by hypoxia, indicating that HIF-1 mediates cell-autonomous
activation of endothelial cells. </pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><a href='http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15374877' target='EXTERNAL'>15374877</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'>Vascular,Oligonucleotide Array Sequence Analysis,P.H.S.,Pulmonary Artery/cytology,Endothelium,Anoxia,Humans,genetics,Mutagenesis,Trans-Activation (Genetics)/physiology,Transcription Factors,cytology,physiology,physiopathology,Endothelial Cells/physiology</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Human</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'>Kate Stafford</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='HYPOXIA_UP_MANALO.grp'>grp</a>|<a href='HYPOXIA_UP_MANALO.xml'>xml</a>|<a href='HYPOXIA_UP_MANALO.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>107 genes, 107 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>STC1</td><td>stanniocalcin 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=STC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?STC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TCF8</td><td>transcription factor 8 (represses interleukin 2 expression)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TCF8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TCF8' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SOX4</td><td>SRY (sex determining region Y)-box 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SOX4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SOX4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRIO</td><td>triple functional domain (PTPRF interacting)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRIO' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRIO' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>OPN3</td><td>opsin 3 (encephalopsin, panopsin)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=OPN3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?OPN3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITPR2</td><td>inositol 1,4,5-triphosphate receptor, type 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITPR2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITPR2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTGS1</td><td>prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTGS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTGS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HIF3A</td><td>hypoxia inducible factor 3, alpha subunit</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HIF3A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HIF3A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF10B</td><td>tumor necrosis factor receptor superfamily, member 10b</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF10B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF10B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SHOX2</td><td>short stature homeobox 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SHOX2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SHOX2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HES1</td><td>hairy and enhancer of split 1, (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HES1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HES1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AK3</td><td>Adenylate kinase 3-like 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>WASF2</td><td>WAS protein family, member 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=WASF2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?WASF2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PAM</td><td>peptidylglycine alpha-amidating monooxygenase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PAM' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PAM' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SSB1</td><td>SPRY domain-containing SOCS box protein SSB-1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SSB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SSB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CREB3L2</td><td>cAMP responsive element binding protein 3-like 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CREB3L2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CREB3L2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZHX2</td><td>transcription factor ZHX2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZHX2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZHX2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>COL18A1</td><td>collagen, type XVIII, alpha 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL18A1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL18A1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLCG2</td><td>phospholipase C, gamma 2 (phosphatidylinositol-specific)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLCG2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLCG2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNG2</td><td>cyclin G2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNG2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNG2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RLN1</td><td>relaxin 1 (H1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RLN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RLN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTPRF</td><td>protein tyrosine phosphatase, receptor type, F</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTPRF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTPRF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LIMS1</td><td>LIM and senescent cell antigen-like domains 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LIMS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LIMS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MEF2A</td><td>MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MEF2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MEF2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF14</td><td>tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF14' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF14' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DUSP6</td><td>dual specificity phosphatase 6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DUSP6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DUSP6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ENPP1</td><td>ectonucleotide pyrophosphatase/phosphodiesterase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ENPP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ENPP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EPOR</td><td>erythropoietin receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EPOR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EPOR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BCL6</td><td>B-cell CLL/lymphoma 6 (zinc finger protein 51)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BCL6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BCL6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CUBN</td><td>cubilin (intrinsic factor-cobalamin receptor)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CUBN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CUBN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CX3CL1</td><td>chemokine (C-X3-C motif) ligand 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CX3CL1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CX3CL1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TCF7L1</td><td>transcription factor 7-like 1 (T-cell specific, HMG-box)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TCF7L1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TCF7L1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ADM</td><td>adrenomedullin</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ADM' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ADM' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ERO1L</td><td>ERO1-like (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ERO1L' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ERO1L' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>INSR</td><td>insulin receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=INSR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?INSR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDH2</td><td>cadherin 2, type 1, N-cadherin (neuronal)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDH2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDH2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HIVEP2</td><td>human immunodeficiency virus type I enhancer binding protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HIVEP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HIVEP2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>STC2</td><td>stanniocalcin 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=STC2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?STC2' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>COL5A1</td><td>collagen, type V, alpha 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL5A1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL5A1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>COL4A1</td><td>collagen, type IV, alpha 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL4A1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL4A1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NOTCH4</td><td>Notch homolog 4 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NOTCH4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NOTCH4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AXL</td><td>AXL receptor tyrosine kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AXL' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AXL' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDKN1C</td><td>cyclin-dependent kinase inhibitor 1C (p57, Kip2)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDKN1C' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDKN1C' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CXCR4</td><td>chemokine (C-X-C motif) receptor 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CXCR4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CXCR4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAFF</td><td>v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAFF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAFF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLOD2</td><td>procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLOD2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLOD2' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>INHBA</td><td>inhibin, beta A (activin A, activin AB alpha polypeptide)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=INHBA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?INHBA' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>ANGPTL4</td><td>angiopoietin-like 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ANGPTL4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ANGPTL4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GABRP</td><td>gamma-aminobutyric acid (GABA) A receptor, pi</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GABRP' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GABRP' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GDF10</td><td>growth differentiation factor 10</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GDF10' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GDF10' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GADD45B</td><td>growth arrest and DNA-damage-inducible, beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GADD45B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GADD45B' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr></tr><tr><td>PELI2</td><td>pellino homolog 2 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PELI2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PELI2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LOXL2</td><td>lysyl oxidase-like 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LOXL2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LOXL2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CKIP-1</td><td>CK2 interacting protein 1; HQ0024c protein</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CKIP-1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CKIP-1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RGS3</td><td>regulator of G-protein signalling 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RGS3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RGS3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ACVR1B</td><td>activin A receptor, type IB</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ACVR1B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ACVR1B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTGIS</td><td>prostaglandin I2 (prostacyclin) synthase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTGIS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTGIS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VLDLR</td><td>very low density lipoprotein receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VLDLR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VLDLR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASK</td><td>calcium/calmodulin-dependent serine protein kinase (MAGUK family)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDZK3</td><td>PDZ domain containing 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDZK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDZK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPARG</td><td>peroxisome proliferative activated receptor, gamma</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPARG' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPARG' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPS6KA2</td><td>ribosomal protein S6 kinase, 90kDa, polypeptide 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPS6KA2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPS6KA2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EDN1</td><td>endothelin 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EDN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EDN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>COL4A2</td><td>collagen, type IV, alpha 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL4A2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL4A2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTPRR</td><td>protein tyrosine phosphatase, receptor type, R</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTPRR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTPRR' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>MXI1</td><td>MAX interacting protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MXI1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MXI1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LOX</td><td>lysyl oxidase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LOX' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LOX' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EGLN1</td><td>egl nine homolog 1 (C. elegans)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EGLN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EGLN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZBTB1</td><td>zinc finger and BTB domain containing 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZBTB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZBTB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NPR1</td><td>natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NPR1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NPR1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VEGF</td><td>vascular endothelial growth factor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VEGF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VEGF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TLE1</td><td>transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TLE1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TLE1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CMKOR1</td><td>chemokine orphan receptor 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CMKOR1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CMKOR1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ADORA2A</td><td>adenosine A2a receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ADORA2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ADORA2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RRAS</td><td>related RAS viral (r-ras) oncogene homolog</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RRAS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RRAS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FKBP9</td><td>FK506 binding protein 9, 63 kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FKBP9' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FKBP9' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NPAS2</td><td>neuronal PAS domain protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NPAS2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NPAS2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EGLN3</td><td>egl nine homolog 3 (C. elegans)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EGLN3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EGLN3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RASSF2</td><td>Ras association (RalGDS/AF-6) domain family 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RASSF2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RASSF2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SIRT3</td><td>sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SIRT3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SIRT3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BHLHB2</td><td>basic helix-loop-helix domain containing, class B, 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BHLHB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BHLHB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GRK5</td><td>G protein-coupled receptor kinase 5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GRK5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GRK5' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>IGFBP3</td><td>insulin-like growth factor binding protein 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IGFBP3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IGFBP3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RHOBTB1</td><td>Rho-related BTB domain containing 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RHOBTB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RHOBTB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>INHBE</td><td>activin beta E</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=INHBE' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?INHBE' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LEPR</td><td>leptin receptor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LEPR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LEPR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZNF292</td><td>zinc finger protein 292</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZNF292' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZNF292' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDGFB</td><td>platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDGFB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDGFB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>P4HA2</td><td>procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=P4HA2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?P4HA2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NDRG1</td><td>N-myc downstream regulated gene 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NDRG1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NDRG1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TXNIP</td><td>thioredoxin interacting protein</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TXNIP' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TXNIP' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>COL1A2</td><td>collagen, type I, alpha 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL1A2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL1A2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VEGFC</td><td>vascular endothelial growth factor C</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VEGFC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VEGFC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTPRB</td><td>protein tyrosine phosphatase, receptor type, B</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTPRB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTPRB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITM2A</td><td>integral membrane protein 2A</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITM2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITM2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PGF</td><td>placental growth factor, vascular endothelial growth factor-related protein</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PGF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PGF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFATC4</td><td>nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFATC4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFATC4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>COL9A1</td><td>collagen, type IX, alpha 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=COL9A1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?COL9A1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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