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Gene set: DNA_DAMAGE_SIGNALLING (C2:EXCU:0019)
Standard nameDNA_DAMAGE_SIGNALLING
Systematic nameC2:EXCU:0019
Brief descriptionGenes involved in DNA damage signaling
CategoryC2: Curated
Sub-categoryEXCU: Expert curation
Full description or Abstract
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Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman
Contributed byBroad Institute
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

95 genes, 95 accessions (Toggle view)

GeneTitleLinks
HUS1HUS1 checkpoint homolog (S. pombe)Source|GeneCards
GTSE1G-2 and S-phase expressed 1Source|GeneCards
FEN1flap structure-specific endonuclease 1Source|GeneCards
ERCC5me))Source|GeneCards
TREX1three prime repair exonuclease 1Source|GeneCards
BTG2BTG family, member 2Source|GeneCards
XPAxeroderma pigmentosum, complementation group ASource|GeneCards
PURApurine-rich element binding protein ASource|GeneCards
APEX1APEX nuclease (multifunctional DNA repair enzyme) 1Source|GeneCards
BIRC2baculoviral IAP repeat-containing 2Source|GeneCards
RAD9ARAD9 homolog A (S. pombe)Source|GeneCards
RAD23ARAD23 homolog A (S. cerevisiae)Source|GeneCards
CHEK1CHK1 checkpoint homolog (S. pombe)Source|GeneCards
LGMNlegumainSource|GeneCards
PMS2PMS2 postmeiotic segregation increased 2 (S. cerevisiae)Source|GeneCards
BRCA1breast cancer 1, early onsetSource|GeneCards
TNFRSF10Btumor necrosis factor receptor superfamily, member 10bSource|GeneCards
UNGuracil-DNA glycosylaseSource|GeneCards
PRKDCprotein kinase, DNA-activated, catalytic polypeptideSource|GeneCards
CDC6CDC6 cell division cycle 6 homolog (S. cerevisiae)Source|GeneCards
TNFtumor necrosis factor (TNF superfamily, member 2)Source|GeneCards
PTPRCAPprotein tyrosine phosphatase, receptor type, C-associated proteinSource|GeneCards
BIRC3baculoviral IAP repeat-containing 3Source|GeneCards
RAD52RAD52 homolog (S. cerevisiae)Source|GeneCards
CDC25Acell division cycle 25ASource|GeneCards
XPCxeroderma pigmentosum, complementation group CSource|GeneCards
CDC25Bcell division cycle 25BSource|GeneCards
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)Source|GeneCards
BAK1BCL2-antagonist/killer 1Source|GeneCards
LIG4ligase IV, DNA, ATP-dependentSource|GeneCards
TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)Source|GeneCards
ERCC4excision repair cross-complementing rodent repair deficiency, complementation group 4Source|GeneCards
MDM2Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)Source|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
PIN1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1Source|GeneCards
RAD1RAD1 homolog (S. pombe)Source|GeneCards
ATRXalpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)Source|GeneCards
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)Source|GeneCards
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)Source|GeneCards
CHEK2CHK2 checkpoint homolog (S. pombe)Source|GeneCards
RRM2Bribonucleotide reductase M2 B (TP53 inducible)Source|GeneCards
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)Source|GeneCards
XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2Source|GeneCards
ERCC2excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)Source|GeneCards
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
BCL6B-cell CLL/lymphoma 6 (zinc finger protein 51)Source|GeneCards
DDB1damage-specific DNA binding protein 1, 127kDaSource|GeneCards
XRCC1X-ray repair complementing defective repair in Chinese hamster cells 1Source|GeneCards
H2AFYH2A histone family, member YSource|GeneCards
RPL13Aribosomal protein L13aSource|GeneCards
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3Source|GeneCards
BRCA2breast cancer 2, early onsetSource|GeneCards
CDC25Ccell division cycle 25CSource|GeneCards
MSH3mutS homolog 3 (E. coli)Source|GeneCards
RAD17RAD17 homolog (S. pombe)Source|GeneCards
GADD45Agrowth arrest and DNA-damage-inducible, alphaSource|GeneCards
LRDDleucine-rich and death domain containingSource|GeneCards
WEE1WEE1 homolog (S. pombe)Source|GeneCards
BAXBCL2-associated X proteinSource|GeneCards
CDKN2Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)Source|GeneCards
BBC3BCL2 binding component 3Source|GeneCards
PPIApeptidylprolyl isomerase A (cyclophilin A)Source|GeneCards
ARTNarteminSource|GeneCards
FOXO3Aforkhead box O3ASource|GeneCards
CDS1CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1Source|GeneCards
CDC20CDC20 cell division cycle 20 homolog (S. cerevisiae)Source|GeneCards
TERTtelomerase reverse transcriptaseSource|GeneCards
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 4Source|GeneCards
REV3LREV3-like, catalytic subunit of DNA polymerase zeta (yeast)Source|GeneCards
MSH6mutS homolog 6 (E. coli)Source|GeneCards
ERCC1excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)Source|GeneCards
H2AFZH2A histone family, member ZSource|GeneCards
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)Source|GeneCards
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)Source|GeneCards
PCNAproliferating cell nuclear antigenSource|GeneCards
MPGN-methylpurine-DNA glycosylaseSource|GeneCards
SRPXsushi-repeat-containing protein, X-linkedSource|GeneCards
ATRataxia telangiectasia and Rad3 relatedSource|GeneCards
RAD50RAD50 homolog (S. cerevisiae)Source|GeneCards
GAPDglyceraldehyde-3-phosphate dehydrogenaseSource|GeneCards
GADD45Ggrowth arrest and DNA-damage-inducible, gammaSource|GeneCards
RAD23BRAD23 homolog B (S. cerevisiae)Source|GeneCards
TNFRSF4tumor necrosis factor receptor superfamily, member 4Source|GeneCards
SESN1sestrin 1Source|GeneCards
GADD45Bgrowth arrest and DNA-damage-inducible, betaSource|GeneCards
CDK4cyclin-dependent kinase 4Source|GeneCards
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)Source|GeneCards
REPRIMOcandidate mediator of the p53-dependent G2 arrestSource|GeneCards
PPM1Dprotein phosphatase 1D magnesium-dependent, delta isoformSource|GeneCards
ACTBactin, betaSource|GeneCards
DDB2damage-specific DNA binding protein 2, 48kDaSource|GeneCards
APAF1apoptotic protease activating factorSource|GeneCards


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