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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: HISTONE_DOWN_PEART (C2:PERT:0109)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>HISTONE_DOWN_PEART</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PERT:0109</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Cell-proliferation-related genes downregulated by SAHA and depsipeptide (histone deacetylase inhibitors)</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PERT: Experimental pertuberation</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><p><a onClick="switchAbstract('myvar_a');" title='Toggle abstract view'>Toggle abstract view</a><div id='myvar_a'><pre>Histone deacetylase inhibitors (HDACis) inhibit tumor cell growth
and survival, possibly through their ability to regulate the expression
of specific proliferative and/or apoptotic genes. However, the
HDACi-regulated genes necessary and/or sufficient for their biological
effects remain undefined. We demonstrate that the HDACis suberoylanilide
hydroxamic acid (SAHA) and depsipeptide regulate a highly overlapping
gene set with at least 22% of genes showing altered expression
over a 16-h culture period. SAHA and depsipeptide coordinately
regulated the expression of several genes within distinct apoptosis
and cell cycle pathways. Multiple genes within the Myc, type beta
TGF, cyclin/cyclin-dependent kinase, TNF, Bcl-2, and caspase pathways
were regulated in a manner that favored induction of apoptosis
and decreased cellular proliferation. APAF-1, a gene central to
the intrinsic apoptotic pathway, was induced by SAHA and depsipeptide
and shown to be important, but not essential, for HDACi-induced
cell death. Overexpression of p16(INK4A) and arrest of cells in
G(1) can suppress HDACi-mediated apoptosis. Although p16(INK4A)
did not affect the genome-wide transcription changes mediated
by SAHA, a small number of apoptotic genes, including BCLXL and
B-MYB, were differentially regulated in a manner consistent with
attenuated HDACi-mediated apoptosis in arrested cells. We demonstrate
that different HDACi alter transcription of a large and common
set of genes that control diverse molecular pathways important
for cell survival and proliferation. The ability of HDACi to target
multiple apoptotic and cell proliferation pathways may provide
a competitive advantage over other chemotherapeutic agents because
suppression/loss of a single pathway may not confer resistance
to these agents. </pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><a href='http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15738394' target='EXTERNAL'>15738394</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Human</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'>Kate Stafford</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='HISTONE_DOWN_PEART.grp'>grp</a>|<a href='HISTONE_DOWN_PEART.xml'>xml</a>|<a href='HISTONE_DOWN_PEART.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>78 genes, 78 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>CD3E</td><td>CD3E antigen, epsilon polypeptide (TiT3 complex)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CD3E' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CD3E' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HMGA1</td><td>high mobility group AT-hook 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HMGA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HMGA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLD3</td><td>polymerase (DNA-directed), delta 3, accessory subunit</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLD3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLD3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TUBE1</td><td>tubulin, epsilon 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TUBE1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TUBE1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HDAC4</td><td>histone deacetylase 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HDAC4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HDAC4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LCK</td><td>lymphocyte-specific protein tyrosine kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LCK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LCK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NME1</td><td>non-metastatic cells 1, protein (NM23A) expressed in</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NME1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NME1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>C6ORF108</td><td>chromosome 6 open reading frame 108</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=C6ORF108' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?C6ORF108' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ATF5</td><td>activating transcription factor 5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ATF5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ATF5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>WT1</td><td>Wilms tumor 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=WT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?WT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NUBP1</td><td>nucleotide binding protein 1 (MinD homolog, E. coli)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NUBP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NUBP1' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>RAD21</td><td>RAD21 homolog (S. pombe)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAD21' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAD21' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>S100A11</td><td>S100 calcium binding protein A11 (calgizzarin)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=S100A11' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?S100A11' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HDGF</td><td>hepatoma-derived growth factor (high-mobility group protein 1-like)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HDGF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HDGF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNB2</td><td>cyclin B2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM5</td><td>MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PA2G4</td><td>proliferation-associated 2G4, 38kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PA2G4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PA2G4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LST1</td><td>Leukocyte specific transcript 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LST1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LST1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GFI1</td><td>growth factor independent 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GFI1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GFI1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLK4</td><td>polo-like kinase 4 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLK4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLK4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RAD51L3</td><td>RAD51-like 3 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAD51L3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAD51L3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLE2</td><td>polymerase (DNA directed), epsilon 2 (p59 subunit)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLE2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLE2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MYC</td><td>V-myc myelocytomatosis viral oncogene homolog (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MYC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MYC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>REPIN1</td><td>replication initiator 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=REPIN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?REPIN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZNF330</td><td>zinc finger protein 330</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZNF330' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZNF330' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RBM14</td><td>RNA binding motif protein 14</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RBM14' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RBM14' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GRN</td><td>granulin</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GRN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GRN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CUL1</td><td>cullin 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CUL1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CUL1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFIC</td><td>nuclear factor I/C (CCAAT-binding transcription factor)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFIC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFIC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>USP16</td><td>ubiquitin specific peptidase 16</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=USP16' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?USP16' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IFITM1</td><td>interferon induced transmembrane protein 1 (9-27)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IFITM1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IFITM1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZAK</td><td>sterile alpha motif and leucine zipper containing kinase AZK</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZAK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZAK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TFDP2</td><td>transcription factor Dp-2 (E2F dimerization partner 2)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TFDP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TFDP2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TP53</td><td>tumor protein p53 (Li-Fraumeni syndrome)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TP53' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TP53' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NF1</td><td>neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NF1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TLK1</td><td>tousled-like kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TLK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TLK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AIF1</td><td>allograft inflammatory factor 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AIF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AIF1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ILF3</td><td>interleukin enhancer binding factor 3, 90kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ILF3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ILF3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DTYMK</td><td>deoxythymidylate kinase (thymidylate kinase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DTYMK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DTYMK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNE2</td><td>cyclin E2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNE2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNE2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLK1</td><td>polo-like kinase 1 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CETN3</td><td>centrin, EF-hand protein, 3 (CDC31 homolog, yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CETN3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CETN3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM3</td><td>MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TFDP1</td><td>transcription factor Dp-1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TFDP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TFDP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>EMP3</td><td>epithelial membrane protein 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=EMP3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?EMP3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CTBP1</td><td>C-terminal binding protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CTBP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CTBP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZMYND11</td><td>zinc finger, MYND domain containing 11</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZMYND11' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZMYND11' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF8</td><td>tumor necrosis factor receptor superfamily, member 8</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF8' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IL2RG</td><td>interleukin 2 receptor, gamma (severe combined immunodeficiency)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IL2RG' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IL2RG' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NME2</td><td>non-metastatic cells 2, protein (NM23B) expressed in</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NME2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NME2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>KATNA1</td><td>katanin p60 (ATPase-containing) subunit A 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=KATNA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?KATNA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CSE1L</td><td>CSE1 chromosome segregation 1-like (yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CSE1L' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CSE1L' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BCAT1</td><td>branched chain aminotransferase 1, cytosolic</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BCAT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BCAT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PFDN1</td><td>prefoldin 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PFDN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PFDN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDK2AP1</td><td>CDK2-associated protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDK2AP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDK2AP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM7</td><td>MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SUV39H1</td><td>suppressor of variegation 3-9 homolog 1 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SUV39H1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SUV39H1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VMD2</td><td>vitelliform macular dystrophy (Best disease, bestrophin)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VMD2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VMD2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RIOK3</td><td>RIO kinase 3 (yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RIOK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RIOK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RAN</td><td>RAN, member RAS oncogene family</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PMS1</td><td>PMS1 postmeiotic segregation increased 1 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PMS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PMS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IGHMBP2</td><td>immunoglobulin mu binding protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IGHMBP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IGHMBP2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NBS1</td><td>Nibrin</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NBS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NBS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BST2</td><td>bone marrow stromal cell antigen 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BST2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BST2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IL8</td><td>interleukin 8</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IL8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IL8' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IFRD2</td><td>interferon-related developmental regulator 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IFRD2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IFRD2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CTCF</td><td>CCCTC-binding factor (zinc finger protein)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CTCF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CTCF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SIPA1</td><td>signal-induced proliferation-associated gene 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SIPA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SIPA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UBE2C</td><td>ubiquitin-conjugating enzyme E2C</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UBE2C' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UBE2C' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDC7</td><td>CDC7 cell division cycle 7 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDC7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDC7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP2R1A</td><td>protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP2R1A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP2R1A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZWINT</td><td>ZW10 interactor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZWINT' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZWINT' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LIG3</td><td>ligase III, DNA, ATP-dependent</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LIG3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LIG3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NCOA6</td><td>nuclear receptor coactivator 6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NCOA6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NCOA6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>KNTC1</td><td>kinetochore associated 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=KNTC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?KNTC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>IFI16</td><td>interferon, gamma-inducible protein 16</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=IFI16' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?IFI16' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>STK6</td><td>serine/threonine kinase 6</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=STK6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?STK6' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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