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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: HYPOXIA_DOWN_MANALO (C2:PERT:0101)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>HYPOXIA_DOWN_MANALO</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PERT:0101</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Genes downregulated in human pulmonary endothelial cells under hypoxic conditions or after exposure to AdCA5, an adenovirus carrying constitutively active hypoxia-inducible factor 1 (HIF-1alpha).</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PERT: Experimental pertuberation</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>Hypoxia-inducible factor 1 (HIF-1) activates transcription of
genes encoding angiogenic growth factors, which are secreted by
hypoxic cells and stimulate endothelial cells, leading to angiogenesis.
To determine whether HIF-1 also mediates cell-autonomous responses
to hypoxia, we have compared gene expression profiles in arterial
endothelial cells cultured under nonhypoxic versus hypoxic conditions
and in nonhypoxic cells infected with adenovirus encoding beta-galactosidase
versus a constitutively active form of HIF-1alpha (AdCA5). There
were 245 gene probes that showed at least 1.5-fold increase in
expression in response to hypoxia and in response to AdCA5; 325
gene probes showed at least 1.5-fold decrease in expression in
response to hypoxia and in response to AdCA5. The largest category
of genes down-regulated by both hypoxia and AdCA5 encoded proteins
involved in cell growth/proliferation. Many genes up-regulated
by both hypoxia and AdCA5 encoded cytokines/growth factors, receptors,
and other signaling proteins. Transcription factors accounted
for the largest group of HIF-1-regulated genes, indicating that
HIF-1 controls a network of transcriptional responses to hypoxia
in endothelial cells. Infection of endothelial cells with AdCA5
under nonhypoxic conditions was sufficient to induce increased
basement membrane invasion and tube formation similar to the responses
induced by hypoxia, indicating that HIF-1 mediates cell-autonomous
activation of endothelial cells. </pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><a href='http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15374877' target='EXTERNAL'>15374877</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'>Vascular,Oligonucleotide Array Sequence Analysis,P.H.S.,Pulmonary Artery/cytology,Endothelium,Anoxia,Humans,genetics,Mutagenesis,Trans-Activation (Genetics)/physiology,Transcription Factors,cytology,physiology,physiopathology,Endothelial Cells/physiology</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Human</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'>Kate Stafford</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='HYPOXIA_DOWN_MANALO.grp'>grp</a>|<a href='HYPOXIA_DOWN_MANALO.xml'>xml</a>|<a href='HYPOXIA_DOWN_MANALO.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>91 genes, 91 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>SNRPD1</td><td>Small nuclear ribonucleoprotein D1 polypeptide 16kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SNRPD1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SNRPD1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DDX23</td><td>DEAD (Asp-Glu-Ala-Asp) box polypeptide 23</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DDX23' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DDX23' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRC1</td><td>protein regulator of cytokinesis 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAD2L1</td><td>MAD2 mitotic arrest deficient-like 1 (yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAD2L1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAD2L1' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>SNAPC5</td><td>small nuclear RNA activating complex, polypeptide 5, 19kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SNAPC5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SNAPC5' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>NOL5A</td><td>nucleolar protein 5A (56kDa with KKE/D repeat)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NOL5A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NOL5A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>USP1</td><td>ubiquitin specific protease 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=USP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?USP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>USP39</td><td>ubiquitin specific protease 39</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=USP39' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?USP39' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RNU3IP2</td><td>RNA, U3 small nucleolar interacting protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RNU3IP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RNU3IP2' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>MCM5</td><td>MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSMD11</td><td>proteasome (prosome, macropain) 26S subunit, non-ATPase, 11</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSMD11' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSMD11' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLD2</td><td>polymerase (DNA directed), delta 2, regulatory subunit 50kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLD2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLD2' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>PA2G4</td><td>proliferation-associated 2G4, 38kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PA2G4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PA2G4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ASK</td><td>activator of S phase kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ASK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ASK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAZ</td><td>MYC-associated zinc finger protein (purine-binding transcription factor)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAZ' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAZ' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MLLT10</td><td>myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MLLT10' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MLLT10' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GTPBP4</td><td>GTP binding protein 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GTPBP4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GTPBP4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM6</td><td>MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BRCA1</td><td>breast cancer 1, early onset</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BRCA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BRCA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLE2</td><td>polymerase (DNA directed), epsilon 2 (p59 subunit)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLE2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLE2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRIP13</td><td>thyroid hormone receptor interactor 13</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRIP13' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRIP13' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDC6</td><td>CDC6 cell division cycle 6 homolog (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDC6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDC6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BOP1</td><td>block of proliferation 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BOP1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BOP1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MPHOSPH9</td><td>M-phase phosphoprotein 9</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MPHOSPH9' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MPHOSPH9' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RRS1</td><td>RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RRS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RRS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MRPS12</td><td>mitochondrial ribosomal protein S12</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MRPS12' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MRPS12' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DDX18</td><td>DEAD (Asp-Glu-Ala-Asp) box polypeptide 18</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DDX18' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DDX18' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ORC6L</td><td>origin recognition complex, subunit 6 homolog-like (yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ORC6L' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ORC6L' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPP30</td><td>ribonuclease P (30kD)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPP30' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPP30' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM4</td><td>MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RRM1</td><td>ribonucleotide reductase M1 polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RRM1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RRM1' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>PPARD</td><td>peroxisome proliferative activated receptor, delta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPARD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPARD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DHX35</td><td>DEAH (Asp-Glu-Ala-His) box polypeptide 35</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DHX35' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DHX35' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNE1</td><td>cyclin E1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNE1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNE1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ID1</td><td>inhibitor of DNA binding 1, dominant negative helix-loop-helix protein</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ID1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ID1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NOLC1</td><td>nucleolar and coiled-body phosphoprotein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NOLC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NOLC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HNRPU</td><td>heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HNRPU' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HNRPU' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DNA2L</td><td>DNA2 DNA replication helicase 2-like (yeast)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DNA2L' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DNA2L' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SNRPD3</td><td>small nuclear ribonucleoprotein D3 polypeptide 18kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SNRPD3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SNRPD3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RRM2</td><td>ribonucleotide reductase M2 polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RRM2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RRM2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DHFR</td><td>dihydrofolate reductase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DHFR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DHFR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SNRPA1</td><td>small nuclear ribonucleoprotein polypeptide A'</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SNRPA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SNRPA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ILF3</td><td>interleukin enhancer binding factor 3, 90kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ILF3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ILF3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DDX11</td><td>DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DDX11' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DDX11' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNE2</td><td>cyclin E2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNE2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNE2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UBE2S</td><td>ubiquitin-conjugating enzyme E2S</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UBE2S' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UBE2S' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLG</td><td>polymerase (DNA directed), gamma</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLG' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLG' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TFAM</td><td>transcription factor A, mitochondrial</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TFAM' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TFAM' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM2</td><td>MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>POLR3K</td><td>polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=POLR3K' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?POLR3K' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HNRPDL</td><td>heterogeneous nuclear ribonucleoprotein D-like</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HNRPDL' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HNRPDL' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MRPL46</td><td>mitochondrial ribosomal protein L46</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MRPL46' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MRPL46' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>UCHL5</td><td>ubiquitin carboxyl-terminal hydrolase L5</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UCHL5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UCHL5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RPL39</td><td>ribosomal protein L39</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RPL39' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RPL39' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM3</td><td>MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ATIC</td><td>5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ATIC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ATIC' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>CHAF1A</td><td>chromatin assembly factor 1, subunit A (p150)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CHAF1A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CHAF1A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RFC2</td><td>replication factor C (activator 1) 2, 40kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RFC2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RFC2' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>UMPS</td><td>uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=UMPS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?UMPS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RFC3</td><td>replication factor C (activator 1) 3, 38kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RFC3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RFC3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PFS2</td><td>DNA replication complex GINS protein PSF2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PFS2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PFS2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MFN2</td><td>mitofusin 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MFN2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MFN2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSME3</td><td>proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSME3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSME3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MRPL40</td><td>mitochondrial ribosomal protein L40</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MRPL40' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MRPL40' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CTPS</td><td>CTP synthase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CTPS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CTPS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SKP2</td><td>S-phase kinase-associated protein 2 (p45)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SKP2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SKP2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MCM10</td><td>MCM10 minichromosome maintenance deficient 10 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MCM10' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MCM10' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZNF500</td><td>zinc finger protein 500</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZNF500' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZNF500' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>HNRPD</td><td>heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HNRPD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HNRPD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TSFM</td><td>Ts translation elongation factor, mitochondrial</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TSFM' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TSFM' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PSME4</td><td>proteasome (prosome, macropain) activator subunit 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PSME4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PSME4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RFC5</td><td>replication factor C (activator 1) 5, 36.5kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RFC5' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RFC5' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRPS1</td><td>phosphoribosyl pyrophosphate synthetase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRPS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRPS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CCNF</td><td>cyclin F</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CCNF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CCNF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDC2</td><td>cell division cycle 2, G1 to S and G2 to M</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDC2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDC2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CDC7</td><td>CDC7 cell division cycle 7 (S. cerevisiae)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CDC7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDC7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BARD1</td><td>BRCA1 associated RING domain 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BARD1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BARD1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ZWINT</td><td>ZW10 interactor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ZWINT' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ZWINT' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SFRS2</td><td>splicing factor, arginine/serine-rich 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SFRS2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SFRS2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NEK4</td><td>NIMA (never in mitosis gene a)-related kinase 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NEK4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NEK4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RB1</td><td>retinoblastoma 1 (including osteosarcoma)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DDX21</td><td>DEAD (Asp-Glu-Ala-Asp) box polypeptide 21</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DDX21' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DDX21' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ELK1</td><td>ELK1, member of ETS oncogene family</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ELK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ELK1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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