[an error occurred while processing this directive]
Gene set: P53_SIGNALLING (C2:EXCU:0039)
Standard nameP53_SIGNALLING
Systematic nameC2:EXCU:0039
Brief descriptionGenes involved in p53 signaling
CategoryC2: Curated
Sub-categoryEXCU: Expert curation
Full description or Abstract
na
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman
Contributed byBroad Institute
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

101 genes, 101 accessions (Toggle view)

GeneTitleLinks
BZRPbenzodiazapine receptor (peripheral)Source|GeneCards
WRNWerner syndromeSource|GeneCards
RELAv-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)Source|GeneCards
WT1Wilms tumor 1Source|GeneCards
NDRG4NDRG family member 4Source|GeneCards
CCNHcyclin HSource|GeneCards
APEX1APEX nuclease (multifunctional DNA repair enzyme) 1Source|GeneCards
SIRT1sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)Source|GeneCards
CTSDcathepsin D (lysosomal aspartyl protease)Source|GeneCards
CHEK1CHK1 checkpoint homolog (S. pombe)Source|GeneCards
MAP2K7mitogen-activated protein kinase kinase 7Source|GeneCards
TP53BP2tumor protein p53 binding protein, 2Source|GeneCards
BRCA1breast cancer 1, early onsetSource|GeneCards
MYCV-myc myelocytomatosis viral oncogene homolog (avian)Source|GeneCards
TNFRSF10Btumor necrosis factor receptor superfamily, member 10bSource|GeneCards
TNFtumor necrosis factor (TNF superfamily, member 2)Source|GeneCards
EP300E1A binding protein p300Source|GeneCards
ACTA1actin, alpha 1, skeletal muscleSource|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
DAXXdeath-associated protein 6Source|GeneCards
ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1Source|GeneCards
CREBBPCREB binding protein (Rubinstein-Taybi syndrome)Source|GeneCards
CASP9caspase 9, apoptosis-related cysteine proteaseSource|GeneCards
STAT5Asignal transducer and activator of transcription 5ASource|GeneCards
PRKCB1protein kinase C, beta 1Source|GeneCards
HIPK2homeodomain interacting protein kinase 2Source|GeneCards
GADD45Agrowth arrest and DNA-damage-inducible, alphaSource|GeneCards
MAP4microtubule-associated protein 4Source|GeneCards
PMP22peripheral myelin protein 22Source|GeneCards
PPIApeptidylprolyl isomerase A (cyclophilin A)Source|GeneCards
PMAIP1phorbol-12-myristate-13-acetate-induced protein 1Source|GeneCards
TRAF5TNF receptor-associated factor 5Source|GeneCards
PRKCGprotein kinase C, gammaSource|GeneCards
ATRataxia telangiectasia and Rad3 relatedSource|GeneCards
CDC2cell division cycle 2, G1 to S and G2 to MSource|GeneCards
CSNK2A2casein kinase 2, alpha prime polypeptideSource|GeneCards
TRAF1TNF receptor-associated factor 1Source|GeneCards
RB1retinoblastoma 1 (including osteosarcoma)Source|GeneCards
REPRIMOcandidate mediator of the p53-dependent G2 arrestSource|GeneCards
APAF1apoptotic protease activating factorSource|GeneCards
GTSE1G-2 and S-phase expressed 1Source|GeneCards
BRAPBRCA1 associated proteinSource|GeneCards
NDRG2NDRG family member 2Source|GeneCards
TRAF4TNF receptor-associated factor 4Source|GeneCards
BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)Source|GeneCards
TP53AP1TP53 activated protein 1Source|GeneCards
NDRG3NDRG family member 3Source|GeneCards
PRKDCprotein kinase, DNA-activated, catalytic polypeptideSource|GeneCards
BCL2B-cell CLL/lymphoma 2Source|GeneCards
MTBPMdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDaSource|GeneCards
NUMBnumb homolog (Drosophila)Source|GeneCards
PRKCAprotein kinase C, alphaSource|GeneCards
CDK7cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)Source|GeneCards
TP73tumor protein p73Source|GeneCards
HSPA4heat shock 70kDa protein 4Source|GeneCards
TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor)Source|GeneCards
MDM2Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)Source|GeneCards
EI24etoposide induced 2.4 mRNASource|GeneCards
HIF1Ahypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Source|GeneCards
BAI1brain-specific angiogenesis inhibitor 1Source|GeneCards
CSNK2A1casein kinase 2, alpha 1 polypeptideSource|GeneCards
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)Source|GeneCards
TP73Ltumor protein p73-likeSource|GeneCards
CHEK2CHK2 checkpoint homolog (S. pombe)Source|GeneCards
RRM2Bribonucleotide reductase M2 B (TP53 inducible)Source|GeneCards
PMLpromyelocytic leukemiaSource|GeneCards
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
P53AIP1p53-regulated apoptosis-inducing protein 1Source|GeneCards
ESR1estrogen receptor 1Source|GeneCards
CSNK2Bcasein kinase 2, beta polypeptideSource|GeneCards
SP1Sp1 transcription factorSource|GeneCards
RPL13Aribosomal protein L13aSource|GeneCards
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2Source|GeneCards
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Source|GeneCards
LRDDleucine-rich and death domain containingSource|GeneCards
BAXBCL2-associated X proteinSource|GeneCards
BBC3BCL2 binding component 3Source|GeneCards
PRKCQprotein kinase C, thetaSource|GeneCards
MAP2K4mitogen-activated protein kinase kinase 4Source|GeneCards
NDRG1N-myc downstream regulated gene 1Source|GeneCards
TNFAIP1tumor necrosis factor, alpha-induced protein 1 (endothelial)Source|GeneCards
FAF1Fas (TNFRSF6) associated factor 1Source|GeneCards
RASA1RAS p21 protein activator (GTPase activating protein) 1Source|GeneCards
E2F1E2F transcription factor 1Source|GeneCards
SERPINB5serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5Source|GeneCards
FADDFas (TNFRSF6)-associated via death domainSource|GeneCards
TTRAPTRAF and TNF receptor associated proteinSource|GeneCards
WIG1p53 target zinc finger proteinSource|GeneCards
GAPDglyceraldehyde-3-phosphate dehydrogenaseSource|GeneCards
THBS1thrombospondin 1Source|GeneCards
TBPTATA box binding proteinSource|GeneCards
CSNK1A1casein kinase 1, alpha 1Source|GeneCards
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)Source|GeneCards
SFNstratifinSource|GeneCards
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)Source|GeneCards
PCAFp300/CBP-associated factorSource|GeneCards
ACTBactin, betaSource|GeneCards


[an error occurred while processing this directive]