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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: SIG_BCR_SIGNALING_PATHWAY (C2:PATH:0241)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>SIG_BCR_SIGNALING_PATHWAY</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0241</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Members of the BCR signaling pathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'>SignallingAlliance</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='SIG_BCR_SIGNALING_PATHWAY.grp'>grp</a>|<a href='SIG_BCR_SIGNALING_PATHWAY.xml'>xml</a>|<a href='SIG_BCR_SIGNALING_PATHWAY.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>46 genes, 46 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>CD19</td><td>CD19 antigen</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CD19' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CD19' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP1R13B</td><td>protein phosphatase 1, regulatory (inhibitor) subunit 13B</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP1R13B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP1R13B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VAV1</td><td>vav 1 oncogene</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VAV1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VAV1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>INPP5D</td><td>inositol polyphosphate-5-phosphatase, 145kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=INPP5D' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?INPP5D' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SOS1</td><td>son of sevenless homolog 1 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SOS1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SOS1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FLOT2</td><td>flotillin 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FLOT2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FLOT2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP3CC</td><td>protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP3CC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP3CC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK3</td><td>mitogen-activated protein kinase 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT1</td><td>v-akt murine thymoma viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CSK</td><td>c-src tyrosine kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CSK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CSK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PTPRC</td><td>protein tyrosine phosphatase, receptor type, C</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PTPRC' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PTPRC' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP4K1</td><td>mitogen-activated protein kinase kinase kinase kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP4K1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP4K1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SOS2</td><td>son of sevenless homolog 2 (Drosophila)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SOS2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SOS2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITPR2</td><td>inositol 1,4,5-triphosphate receptor, type 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITPR2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITPR2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FLOT1</td><td>Flotillin 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FLOT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FLOT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT3</td><td>v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3R1</td><td>phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3R1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3R1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GSK3A</td><td>glycogen synthase kinase 3 alpha</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GSK3A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GSK3A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3CD</td><td>phosphoinositide-3-kinase, catalytic, delta polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3CD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3CD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NR0B2</td><td>nuclear receptor subfamily 0, group B, member 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NR0B2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NR0B2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFATC2</td><td>nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFATC2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFATC2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SHC1</td><td>SHC (Src homology 2 domain containing) transforming protein 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SHC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SHC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BLNK</td><td>B-cell linker</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BLNK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BLNK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CD81</td><td>CD81 antigen (target of antiproliferative antibody 1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CD81' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CD81' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BCR</td><td>breakpoint cluster region</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BCR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BCR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP3CA</td><td>protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP3CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP3CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RAF1</td><td>v-raf-1 murine leukemia viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RAF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RAF1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITPR1</td><td>inositol 1,4,5-triphosphate receptor, type 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITPR1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITPR1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PPP3CB</td><td>protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PPP3CB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PPP3CB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFATC1</td><td>nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFATC1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFATC1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDK1</td><td>pyruvate dehydrogenase kinase, isoenzyme 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GSK3B</td><td>glycogen synthase kinase 3 beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GSK3B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GSK3B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT2</td><td>v-akt murine thymoma viral oncogene homolog 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BCL2</td><td>B-cell CLL/lymphoma 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BCL2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BCL2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LYN</td><td>v-yes-1 Yamaguchi sarcoma viral related oncogene homolog</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LYN' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LYN' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GRB2</td><td>growth factor receptor-bound protein 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GRB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GRB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BTK</td><td>Bruton agammaglobulinemia tyrosine kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BTK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BTK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PIK3CA</td><td>phosphoinositide-3-kinase, catalytic, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PIK3CA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PIK3CA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PLCG2</td><td>phospholipase C, gamma 2 (phosphatidylinositol-specific)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PLCG2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PLCG2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BAD</td><td>BCL2-antagonist of cell death</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BAD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BAD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CD22</td><td>CD22 antigen</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CD22' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CD22' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CR2</td><td>complement component (3d/Epstein Barr virus) receptor 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CR2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CR2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAPK1</td><td>mitogen-activated protein kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SYK</td><td>spleen tyrosine kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SYK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SYK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DAG1</td><td>dystroglycan 1 (dystrophin-associated glycoprotein 1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DAG1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DAG1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ITPR3</td><td>inositol 1,4,5-triphosphate receptor, type 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ITPR3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ITPR3' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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