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Gene set: UEDA_MOUSE_SCN (C2:PERT:0054)
Standard nameUEDA_MOUSE_SCN
Systematic nameC2:PERT:0054
Brief descriptionGenes identified as time indicators in mouse SCN.
CategoryC2: Curated
Sub-categoryPERT: Experimental pertuberation
Full description or Abstract
Detection of individual body time (BT) via a single-time-point
assay has been a longstanding unfulfilled dream in medicine, because
BT information can be exploited to maximize potency and minimize
toxicity during drug administration and thus will enable highly
optimized medication. To achieve this dream, we created a "molecular
timetable" composed of >100 "time-indicating genes," whose gene
expression levels can represent internal BT. Here we describe
a robust method called the "molecular-timetable method" for BT
detection from a single-time-point expression profile. The power
of this method is demonstrated by the sensitive and accurate detection
of BT and the sensitive diagnosis of rhythm disorders. These results
demonstrate the feasibility of BT detection based on single-time-point
sampling, suggest the potential for expression-based diagnosis
of rhythm disorders, and may translate functional genomics into
chronotherapy and personalized medicine. 
Publication URL15273285
External linksna
Keywords & MeSH headingsGenomics,Sensitivity and Specificity,Male,Oligonucleotide Array Sequence Analysis,Circadian Rhythm,Inbred BALB C,genetics,Mice,standards,methods,diagnosis,Reproducibility of Results,Chronobiology Disorders
OrganismMouse
Contributed byKate Stafford
Source platformMG_U74Av2
Downloadgrp|xml|map
Genes

93 genes, 97 accessions (Toggle view)

AccessionGeneTitleLinks
93503_atSFRP2secreted frizzled-related sequence protein 2Source|GeneCards
96114_atPPP1R1Aprotein phosphatase 1, regulatory (inhibitor) subunit 1ASource|GeneCards
96216_atORMDL1ORM1-like 1 (S. cerevisiae)Source|GeneCards
94322_atSQLEsqualene epoxidaseSource|GeneCards
104628_atMAN2A1mannosidase 2, alpha 1Source|GeneCards
98038_atHMGB3high mobility group box 3Source|GeneCards
96041_atRBM3RNA binding motif protein 3Source|GeneCards
94761_atCCL7chemokine (C-C motif) ligand 7Source|GeneCards
94821_atXBP1X-box binding protein 1Source|GeneCards
161189_r_atAVPR1AArginine vasopressin receptor 1ASource|GeneCards
100946_atHSPA1Bheat shock protein 1BSource|GeneCards
93694_atPER2period homolog 2 (Drosophila)Source|GeneCards
94359_atPLEKHA1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1Source|GeneCards
92913_atABCD2ATP-binding cassette, sub-family D (ALD), member 2Source|GeneCards
96266_atHNRPMheterogeneous nuclear ribonucleoprotein MSource|GeneCards
97224_atPNRC1proline-rich nuclear receptor coactivator 1Source|GeneCards
95679_atCDK2AP2CDK2-associated protein 2Source|GeneCards
95418_atRASL11BRAS-like, family 11, member BSource|GeneCards
160317_atRAB34RAB34, member of RAS oncogene familySource|GeneCards
102955_atNFIL3nuclear factor, interleukin 3, regulatedSource|GeneCards
92611_atGPIAP1GPI-anchored membrane protein 1Source|GeneCards
104139_atP4HA1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptideSource|GeneCards
98149_s_at1110033J19RIKRIKEN cDNA 1110033J19 geneSource|GeneCards
102302_atBCKDHBbranched chain ketoacid dehydrogenase E1, beta polypeptideSource|GeneCards
92487_atSOX7SRY-box containing gene 7Source|GeneCards
95913_atB230333C21RIKRIKEN cDNA B230333C21 geneSource|GeneCards
103443_atAIM1absent in melanoma 1Source|GeneCards
103861_s_atD7WSU128EDNA segment, Chr 7, Wayne State University 128, expressedSource|GeneCards
93381_atAVParginine vasopressinSource|GeneCards
93619_atPER1period homolog 1 (Drosophila)Source|GeneCards
98055_atBLCAPbladder cancer associated protein homolog (human)Source|GeneCards
100708_atH3F3BH3 histone, family 3BSource|GeneCards
92532_atAVPR1Aarginine vasopressin receptor 1ASource|GeneCards
103683_atDHODHdihydroorotate dehydrogenaseSource|GeneCards
96474_atZFP161zinc finger protein 161Source|GeneCards
94034_atSMFNsmall fragment nucleaseSource|GeneCards
101889_s_atRORARAR-related orphan receptor alphaSource|GeneCards
94261_atTHRAP3thyroid hormone receptor associated protein 3Source|GeneCards
96698_atPSMD5proteasome (prosome, macropain) 26S subunit, non-ATPase, 5Source|GeneCards
101975_atDLK1delta-like 1 homolog (Drosophila)Source|GeneCards
101135_atCALCRcalcitonin receptorSource|GeneCards
93868_atNSDHLNAD(P) dependent steroid dehydrogenase-likeSource|GeneCards
99185_at2810443J12RIKRIKEN cDNA 2810443J12 geneSource|GeneCards
103012_atCCL21B /// CCL21A //chemokine (C-C motif) ligand 21b /// chemokine (C-C motif) ligand 21a /// chemokine (C-C motif) ligand 21c (leucine)Source|GeneCards
96653_atRNASET2ribonuclease T2Source|GeneCards
162198_f_atNA
99076_atNR1D2nuclear receptor subfamily 1, group D, member 2Source|GeneCards
160511_atCXCL12chemokine (C-X-C motif) ligand 12Source|GeneCards
93325_atPOLR2Epolymerase (RNA) II (DNA directed) polypeptide ESource|GeneCards
99032_atRASD1RAS, dexamethasone-induced 1Source|GeneCards
98111_atHSP105heat shock protein 105Source|GeneCards
94420_f_atCRY1cryptochrome 1 (photolyase-like)Source|GeneCards
161609_atRGS16regulator of G-protein signaling 16Source|GeneCards
99815_atHRH2histamine receptor H 2Source|GeneCards
162095_f_atGAS7growth arrest specific 7Source|GeneCards
102858_atPKIBprotein kinase inhibitor beta, cAMP dependent, testis specificSource|GeneCards
103029_atPDCD4programmed cell death 4Source|GeneCards
101955_atHSPA5heat shock 70kD protein 5 (glucose-regulated protein)Source|GeneCards
161235_f_atBAT4 /// LOC434585HLA-B associated transcript 4 /// similar to Bat4 proteinSource|GeneCards
94872_atSMPDL3Asphingomyelin phosphodiesterase, acid-like 3ASource|GeneCards
94378_atRGS16regulator of G-protein signaling 16Source|GeneCards
100566_atIGFBP5insulin-like growth factor binding protein 5Source|GeneCards
102382_atARNTLaryl hydrocarbon receptor nuclear translocator-likeSource|GeneCards
160182_atSFRS6splicing factor, arginine/serine-rich 6Source|GeneCards
161666_f_atGADD45Bgrowth arrest and DNA-damage-inducible 45 betaSource|GeneCards
92310_atPLK2polo-like kinase 2 (Drosophila)Source|GeneCards
102081_atROBO3roundabout homolog 3 (Drosophila)Source|GeneCards
101979_atGADD45Ggrowth arrest and DNA-damage-inducible 45 gammaSource|GeneCards
95749_atARMETarginine-rich, mutated in early stage tumorsSource|GeneCards
95737_at1200015A19RIKRIKEN cDNA 1200015A19 geneSource|GeneCards
99575_atUBQLN1ubiquilin 1Source|GeneCards
96954_atSTK24serine/threonine kinase 24 (STE20 homolog, yeast)Source|GeneCards
96254_atDNAJB1DnaJ (Hsp40) homolog, subfamily B, member 1Source|GeneCards
104598_atDUSP1dual specificity phosphatase 1Source|GeneCards
92519_atPHKA1phosphorylase kinase alpha 1Source|GeneCards
93013_atID2inhibitor of DNA binding 2Source|GeneCards
93277_atHSPD1heat shock protein 1 (chaperonin)Source|GeneCards
95704_atAP1B1adaptor protein complex AP-1, beta 1 subunitSource|GeneCards
160179_atTMEM30Atransmembrane protein 30ASource|GeneCards
104183_atNA
96076_atSTX5Asyntaxin 5ASource|GeneCards
99100_atSTAT3signal transducer and activator of transcription 3Source|GeneCards
94076_i_atRPN2ribophorin IISource|GeneCards
97890_atSGKserum/glucocorticoid regulated kinaseSource|GeneCards
96122_at2310016A09RIKRIKEN cDNA 2310016A09 geneSource|GeneCards
160841_atDBPD site albumin promoter binding proteinSource|GeneCards
95057_atHERPUD1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1Source|GeneCards
98967_atFABP7fatty acid binding protein 7, brainSource|GeneCards
101381_atRABEP1rabaptin, RAB GTPase binding effector protein 1Source|GeneCards
94207_atPDIA6protein disulfide isomerase associated 6Source|GeneCards
94274_atUBE2Subiquitin-conjugating enzyme E2SSource|GeneCards
102292_atGADD45Agrowth arrest and DNA-damage-inducible 45 alphaSource|GeneCards
93875_atHSPA1Aheat shock protein 1ASource|GeneCards
160330_atCHORDC1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1Source|GeneCards
92767_atBMPR1Abone morphogenetic protein receptor, type 1ASource|GeneCards
104682_atTUBA8tubulin, alpha 8Source|GeneCards
94285_atH2-EB1histocompatibility 2, class II antigen E betaSource|GeneCards


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