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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: deathPathway (C2:PATH:0069)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>deathPathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0069</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Death receptors such as Fas and DR3, 4, and 5 transduce pro-apoptotic signaling by oligomerizing to activate the caspase cascade.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_deathPathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_deathPathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='deathPathway.grp'>grp</a>|<a href='deathPathway.xml'>xml</a>|<a href='deathPathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>33 genes, 33 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>CASP9</td><td>caspase 9, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP9' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP9' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFKBIA</td><td>nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFKBIA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFKBIA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>GAS2</td><td>growth arrest-specific 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=GAS2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?GAS2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP6</td><td>caspase 6, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP6' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP6' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RELA</td><td>v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RELA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RELA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BIRC4</td><td>baculoviral IAP repeat-containing 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BIRC4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BIRC4' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP7</td><td>caspase 7, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP7' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP7' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP3</td><td>caspase 3, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RIPK1</td><td>receptor (TNFRSF)-interacting serine-threonine kinase 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RIPK1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RIPK1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CFLAR</td><td>CASP8 and FADD-like apoptosis regulator</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CFLAR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CFLAR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BIRC2</td><td>baculoviral IAP repeat-containing 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BIRC2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BIRC2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP8</td><td>caspase 8, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP8' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP8' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CASP10</td><td>caspase 10, apoptosis-related cysteine protease</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CASP10' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CASP10' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF10B</td><td>tumor necrosis factor receptor superfamily, member 10b</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF10B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF10B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>LMNA</td><td>lamin A/C</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=LMNA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?LMNA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRAF2</td><td>TNF receptor-associated factor 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRAF2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRAF2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BIRC3</td><td>baculoviral IAP repeat-containing 3</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BIRC3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BIRC3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TRADD</td><td>TNFRSF1A-associated via death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TRADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TRADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BCL2</td><td>B-cell CLL/lymphoma 2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BCL2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BCL2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CHUK</td><td>conserved helix-loop-helix ubiquitous kinase</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CHUK' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CHUK' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SPTAN1</td><td>spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SPTAN1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SPTAN1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FADD</td><td>Fas (TNFRSF6)-associated via death domain</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FADD' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FADD' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFSF10</td><td>tumor necrosis factor (ligand) superfamily, member 10</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFSF10' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFSF10' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>MAP3K14</td><td>mitogen-activated protein kinase kinase kinase 14</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=MAP3K14' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?MAP3K14' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CYCS</td><td>cytochrome c, somatic</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CYCS' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CYCS' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DFFB</td><td>DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DFFB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DFFB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NFKB1</td><td>nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NFKB1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NFKB1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF10A</td><td>tumor necrosis factor receptor superfamily, member 10a</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF10A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF10A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFSF12</td><td>tumor necrosis factor (ligand) superfamily, member 12</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFSF12' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFSF12' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNFRSF25</td><td>tumor necrosis factor receptor superfamily, member 25</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNFRSF25' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNFRSF25' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>DFFA</td><td>DNA fragmentation factor, 45kDa, alpha polypeptide</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=DFFA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?DFFA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BID</td><td>BH3 interacting domain death agonist</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BID' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BID' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>APAF1</td><td>apoptotic protease activating factor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=APAF1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?APAF1' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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