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Gene set: longevityPathway (C2:PATH:0149)
Standard namelongevityPathway
Systematic nameC2:PATH:0149
Brief descriptionCaloric restriction in animals often increases lifespan, which may occur via decreased IGF receptor expression and consequent expression of stress-resistance proteins.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_longevityPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

14 genes, 14 accessions (Toggle view)

GeneTitleLinks
IGF1Rinsulin-like growth factor 1 receptorSource|GeneCards
SOD3superoxide dismutase 3, extracellularSource|GeneCards
CATCatalaseSource|GeneCards
GHRgrowth hormone receptorSource|GeneCards
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homologSource|GeneCards
SOD2superoxide dismutase 2, mitochondrialSource|GeneCards
GH1growth hormone 1Source|GeneCards
AKT1v-akt murine thymoma viral oncogene homolog 1Source|GeneCards
IGF1insulin-like growth factor 1 (somatomedin C)Source|GeneCards
SOD1superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))Source|GeneCards
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptideSource|GeneCards
PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
SHC1SHC (Src homology 2 domain containing) transforming protein 1Source|GeneCards
FOXO3Aforkhead box O3ASource|GeneCards


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