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<hr><table align='center' width='75%' border='0' cols='2'><th colspan='2' class='highlight'>Gene set: no1Pathway (C2:PATH:0175)</th><tr><td bgcolor='#99CCFF' width='25%'>Standard name</td><td width='75%'>no1Pathway</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Systematic name</td><td width='75%'>C2:PATH:0175</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Brief description</td><td width='75%'>Shear stress in endothelial cells increases cytoplasmic calcium, which activates nitric oxide synthase III to release NO, which in turn regulates cardiac contractions.</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Category</td><td width='75%'>C2: Curated</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Sub-category</td><td width='75%'>PATH: Pathway database</td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Full description or Abstract</td><td width='75%'><div id='myvar_a_vis'><pre>na</pre></div></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Publication URL</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>External links</td><td width='75%'>More details for this gene set:<br><a href='http://www.biocarta.com/pathfiles/h_no1Pathway.asp' target='EXTERNAL'>http://www.biocarta.com/pathfiles/h_no1Pathway.asp</a><br></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Keywords & MeSH headings</td><td width='75%'><font color='#C0C0C0'>na</font></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Organism</td><td width='75%'>Generic</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Contributed by</td><td width='75%'><a href='http://www.biocarta.com' target='EXTERNAL'>BioCarta</a></td></tr><tr><td bgcolor='#99CCFF' width='25%'>Source platform</td><td width='75%'>Gene_Symbol</td></tr><tr><td bgcolor='#99CCFF' width='25%'>Download</td><td width='75%'><a href='no1Pathway.grp'>grp</a>|<a href='no1Pathway.xml'>xml</a>|<a href='no1Pathway.xls'>map</a></td></tr><tr><td valign='top' bgcolor='#99CCFF' width='25%'>Genes</td><td><p>31 genes, 31 accessions (<a onClick="switchGeneTable('myvar_g');" title='Toggle view'>Toggle view</a>)<div id='myvar_g'><table cols='3' class='fancy' border='0'><tr><th align='center'>Gene</th><th align='center'>Title</th><th align='center'>Links</th></tr><tr><td>PRKAR2A</td><td>protein kinase, cAMP-dependent, regulatory, type II, alpha</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKAR2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKAR2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>TNNI1</td><td>troponin I, skeletal, slow</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=TNNI1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?TNNI1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDE3A</td><td>phosphodiesterase 3A, cGMP-inhibited</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDE3A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDE3A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>HSPCA</td><td>heat shock 90kDa protein 1, alpha</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=HSPCA' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?HSPCA' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKAR2B</td><td>protein kinase, cAMP-dependent, regulatory, type II, beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKAR2B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKAR2B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKAR1A</td><td>protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKAR1A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKAR1A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>AKT1</td><td>v-akt murine thymoma viral oncogene homolog 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=AKT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?AKT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKG1</td><td>protein kinase, cGMP-dependent, type I</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKG1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKG1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CALM1</td><td>calmodulin 1 (phosphorylase kinase, delta)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CALM1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CALM1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKACG</td><td>protein kinase, cAMP-dependent, catalytic, gamma</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKACG' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKACG' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>NOS3</td><td>nitric oxide synthase 3 (endothelial cell)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=NOS3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?NOS3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FLT1</td><td>fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FLT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FLT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>FLT4</td><td>fms-related tyrosine kinase 4</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=FLT4' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?FLT4' target='EXTERNAL'>GeneCards</a></td></tr><tr></tr><tr><td>SYT1</td><td>synaptotagmin I</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SYT1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SYT1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CALM2</td><td>calmodulin 2 (phosphorylase kinase, delta)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CALM2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CALM2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDE2A</td><td>phosphodiesterase 2A, cGMP-stimulated</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDE2A' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDE2A' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>RYR2</td><td>ryanodine receptor 2 (cardiac)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=RYR2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?RYR2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CALM3</td><td>calmodulin 3 (phosphorylase kinase, delta)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CALM3' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CALM3' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CHRM1</td><td>cholinergic receptor, muscarinic 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CHRM1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CHRM1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKACB</td><td>protein kinase, cAMP-dependent, catalytic, beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKACB' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKACB' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>ACTA1</td><td>actin, alpha 1, skeletal muscle</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=ACTA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?ACTA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>VEGF</td><td>vascular endothelial growth factor</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=VEGF' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?VEGF' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CAV1</td><td>caveolin 1, caveolae protein, 22kDa</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CAV1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CAV1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKAR1B</td><td>protein kinase, cAMP-dependent, regulatory, type I, beta</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKAR1B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKAR1B' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>BDKRB2</td><td>bradykinin receptor B2</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=BDKRB2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?BDKRB2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>CHRNA1</td><td>cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=CHRNA1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CHRNA1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PRKG2</td><td>protein kinase, cGMP-dependent, type II</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PRKG2' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PRKG2' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>SLC7A1</td><td>solute carrier family 7 (cationic amino acid transporter, y+ system), member 1</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=SLC7A1' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?SLC7A1' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>KDR</td><td>kinase insert domain receptor (a type III receptor tyrosine kinase)</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=KDR' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?KDR' target='EXTERNAL'>GeneCards</a></td></tr><tr><td>PDE3B</td><td>phosphodiesterase 3B, cGMP-inhibited</td><td><a href='http://genome-www5.stanford.edu/cgi-bin/SMD/source/sourceResult?option=Name&choice=Gene&organism=Hs&criteria=PDE3B' target='EXTERNAL'>Source</a>|<a href='http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?PDE3B' target='EXTERNAL'>GeneCards</a></td></tr></table></div></td></tr></table></div><br><hr>
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