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Gene set: p53Pathway (C2:PATH:0185)
Standard namep53Pathway
Systematic nameC2:PATH:0185
Brief descriptionp53 induces cell cycle arrest or apoptosis under conditions of DNA damage.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_p53Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

16 genes, 16 accessions (Toggle view)

GeneTitleLinks
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
BCL2B-cell CLL/lymphoma 2Source|GeneCards
E2F1E2F transcription factor 1Source|GeneCards
CDK2cyclin-dependent kinase 2Source|GeneCards
TIMP3tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)Source|GeneCards
PCNAproliferating cell nuclear antigenSource|GeneCards
CCNE1cyclin E1Source|GeneCards
MDM2Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)Source|GeneCards
GADD45Agrowth arrest and DNA-damage-inducible, alphaSource|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
CCND1cyclin D1 (PRAD1: parathyroid adenomatosis 1)Source|GeneCards
BAXBCL2-associated X proteinSource|GeneCards
CDK4cyclin-dependent kinase 4Source|GeneCards
RB1retinoblastoma 1 (including osteosarcoma)Source|GeneCards
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)Source|GeneCards
APAF1apoptotic protease activating factorSource|GeneCards


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