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Gene set: V$CEBP_C (C3:TFAC:0129)
Standard nameV$CEBP_C
Systematic nameC3:TFAC:0129
Brief descriptionGenes with 3'UTR containing motif NGWVTKNKGYAAKNSAYA which matches annotation for CEBPA: CCAAT/enhancer binding protein (C/EBP), alpha
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA C/EBPalpha
 XX
 SY BPc; CBP; C/EBP;
C/EBPalpha; EBP20; LF-H3beta; CCAAT/enhancer binding
 SY protein
alpha.
 XX
 OS rat, Rattus norvegicus
 OC eukaryota;
animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;

OC eutheria; rodentia; myomorpha; muridae; murinae
 XX

XX
 CL C0008; bZIP; 1.1.3.0.1.1.
 XX
 SZ 358 AA; 37.7
kDa (cDNA), 42 kDa (SDS) [46] [45]
 XX
 XX
 FT 1 117
missing in p30(C/EBPalpha) [12].
 FT 1 107 trans-activation
domain.
 FT 1 71 trans-activation element I (TE-I).
 FT
15 15 alternative translation initiation codon [12].
 FT 69
97 trans-activation domain, potential alpha-helix, region 3 [29].

FT 72 96 TE-II.
 FT 107 170 attenuator domain [23].
 FT
118 118 alternative translation initiation codon [12].
 FT
126 199 TE-III.
 FT 126 155 negative regulatory subdomain in
TE-III.
 FT 128 257 weaker trans-activation domain, proline-rich
(130/30) [29]
 FT [23].
 FT 273 306 basic region.
 FT
280 344 PF00170; bZIP.
 FT 280 344 SM00338; BRLZ.
 FT 299
299 Ser-phosphorylation by PKC [16].
 FT 310 345 leucine zipper
(TL5).
 XX
 SF scissors-grip and helical-fork models for
DNA-binding;
 SF scissors grip: upon DNA-binding, the alpha-helices
of the two leucine
 SF zippers extend towards the basic regions
which make the DNA- contacts [43];
 SF as a result, dissociation
constant for homodimerization increases from KD =
 SF 10 nM
to KD = 1 nM in the presence of DNA [2];
 SF a kink has been
postulated between basic subregions A and B at the
 SF conserved
Asn-292, allowing to track the basic region in the major groove

SF around the DNA double helix [43];
 SF proteolytically sensitive
sites between basic subregions A and B and
 SF between basic
region and the leucine zipper [33];
 SF helical-fork: similar
to scissors-grip model, but the basic region forms an
 SF extended
rather than a kinked alpha-helix [35];
 SF highly relaxed DNA-binding
specificity [31] [24];
 SF Y285, N293, and V296 determine the
DNA-binding specificity over that of
 SF GCN4 [8];
 SF the
"hinge region" at the end of the basic region and the beginning
of the
 SF leucine zipper (303-317) defines the spatial relation
between the
 SF half-sites of the bound DNA sequence [8];

SF the mid-regional trans-activating region consists of redundant
modules [29];
 SF the N-terminal part of the molecule exhibits
antimitotic activity [12];
 SF both TE-I and TE-II cooperatively
mediate the contact to TBP and TFIIB [1];
 XX
 CP nonproliferating
liver, adipose, small intestine,adrenal gland, placenta,
 CP
lung, brain, skin [39]; low levels in muscle and thymus [28]

CN heart [39]
 XX
 FF activator [36] [37] [18];
 FF required
for and regulating the terminal adipocyte differentiation [36]

FF [26] [4], thereby reciprocally regulated as and prevented by
c-myc [15];
 FF expressed only in fully differentiated cells
[39];
 FF decreased levels in regenerating liver [17];

FF repressor at the genomes of HBV, SV40 [43];
 FF significant
enhancement of dimerization by Tax [9];
 FF phosphorylation
at S299 attenuates DNA-binding [16];
 FF interaction of C/EBPalpha
with FBR v-Fos inhibits C/EBPalpha and its
 FF effects to induce
adipocyte differentiation and to repress the alpha(III)
 FF
collagen gene [5];
 XX
 IN T01303; ATF4; human, Homo sapiens.

IN T00051; ATF; human, Homo sapiens.
 IN T00108; C/EBPalpha;
rat, Rattus norvegicus.
 IN T00017; C/EBPbeta; mouse, Mus musculus.

IN T00459; C/EBPbeta; rat, Rattus norvegicus.
 IN T00581; C/EBPbeta;
human, Homo sapiens.
 IN T00109; C/EBPdelta; rat, Rattus norvegicus.

IN T01114; C/EBPdelta; mouse, Mus musculus.
 IN T00171; C/EBPepsilon;
rat, Rattus norvegicus.
 IN T00216; C/EBPgamma; mouse, Mus
musculus.
 IN T00127; CHOP-10; mouse, Mus musculus.
 IN
T00794; TBP; human, Homo sapiens.
 IN T02159; TFIIB; rat, Rattus
norvegicus.
 XX
 XX
 XX
 XX
 RN [1]; RE0006251.

RX MEDLINE; 96016204.
 RA Nerlov C., Ziff E. B.
 RT CCAAT/enhancer
binding protein-alpha amino acid motifs with dual TBP and

RT TFIIB binding ability co-operate to activate transcription
in both yeast
 RT and mammalian cells
 RL EMBO J. 14:4318-4328
(1995).
 RN [2]; RE0006669.
 RX MEDLINE; 96080168.
 RA
Krylov D., Olive M., Vinson C.
 RT Extending dimerization interfaces:
the bZIP basic region can form a coiled
 RT coil
 RL EMBO
J. 14:5329-5337 (1995).
 RN [3]; RE0000797.
 RX MEDLINE;
94148226.
 RA Nerlov C., Ziff E. B.
 RT Three levels of
functional interaction determine the activity of
 RT CCAAT/enhancer
binding protein-alpha on the serum albumin promoter
 RL Genes
Dev. 8:350-362 (1994).
 RN [4]; RE0003027.
 RX MEDLINE;
95047322.
 RA Freytag S. O., Paielli D. L., Gilbert J. D.

RT Ectopic expression of the CCAAT/enhancer-binding protein alpha
promotes the
 RT adipogenic program in a variety of mouse fibroblastic
cells
 RL Genes Dev. 8:1654-1663 (1994).
 RN [5]; RE0007060.

RX MEDLINE; 94266835.
 RA Jotte R. M., Kamata N., Holt J. T.

RT Myristylation-dependent transactivation by FBR v-fos is regulated
by C/EBP
 RL J. Biol. Chem. 269:16383-16396 (1994).
 RN
[6]; RE0009831.
 RX MEDLINE; 94344096.
 RA Rana B., Mischoulon
D., Xie Y., Bucher N. L. R., Farmer S. R.
 RT Cell-extracellular
matrix interactions can regulate the switch between
 RT growth
and differentiation in rat hepatocytes: reciprocal expression
of
 RT C/EBPalpha and immediate-early growth response transcription
factors
 RL Mol. Cell. Biol. 14:5858-5869 (1994).
 RN [7];
RE0000787.
 RX MEDLINE; 93279464.
 RA Vinson C. R., Hai
T., Boyd S. M.
 RT Dimerization specificity of the leucine
zipper-containing bZIP motif on DNA
 RT binding: prediction
and rational design
 RL Genes Dev. 7:1047-1058 (1993).

RN [8]; RE0001745.
 RX MEDLINE; 94019364.
 RA Johnson P.
F.
 RT Identification of C/EBP basic region residues involved
in DNA sequence
 RT recognition and half-site spacing preference

RL Mol. Cell. Biol. 13:6919-6930 (1993).
 RN [9]; RE0002710.

RX MEDLINE; 94023981.
 RA Wagner S., Green M. R.
 RT HTLV-I
Tax protein stimulation of DNA binding of bZIP proteins by enhancing

RT dimerization
 RL Science 262:395-399 (1993).
 RN [10];
RE0003025.
 RX MEDLINE; 93261802.
 RA Legraverend C., Antonson
P., Flodby P., Xanthopoulos K. G.
 RT High level activity of
the mouse CCAAT/enhancer binding protein
 RT (C/EBPalpha) gene
promoter involves autoregulation and several ubiquitous
 RT
transcription factors
 RL Nucleic Acids Res. 21:1735- 1742
(1993).
 RN [11]; RE0003038.
 RX MEDLINE; 94022424.

RA Lin F. -T., MacDougald O. A., Diehl A. M., Lane M. D.
 RT
A 30-kDa alternative translation product of the CCAAT/enhancer
binding
 RT protein alpha message: transcriptional activator
lacking antimitotic
 RT activity
 RL Proc. Natl. Acad. Sci.
USA 90:9606-9610 (1993).
 RN [12]; RE0003173.
 RX MEDLINE;
94022424.
 RA Lin F.-T., MacDougald O.A., Diehl A.M., Lane
M.D.
 RT A 30-kDa alternative translation product of the CCAAT/enhancer
binding
 RT protein alpha message: Transcriptional activator
lacking antimitotic
 RT activity
 RL Proc. Natl. Acad. Sci.
USA 90:9606-9610 (1993).
 RN [13]; RE0004524.
 RX MEDLINE;
93309429.
 RA Stein B., Cogswell P. C., Baldwin jr A. S.

RT Functional and physical associations between NF-kappaB and
C/EBP family
 RT members: a Rel domain-bZIP interaction

RL Mol. Cell. Biol. 13:3964-3974 (1993).
 RN [14]; RE0005297.

RX MEDLINE; 93376775.
 RA Ossipow V., Descombes P., Schibler
U.
 RT CCAAT/enhancer-binding protein mRNA is translated into
multiple proteins
 RT with different transcription activation
potentials
 RL Proc. Natl. Acad. Sci. USA 90:8219-8223 (1993).

RN [15]; RE0002777.
 RX MEDLINE; 92229470.
 RA Freytag S.
O., Geddes T. J.
 RT Reciprocal regulation of adipogenesis
by Myc and C/EBPalpha
 RL Science 256:379-382 (1992).
 RN
[16]; RE0003022.
 RX MEDLINE; 92406888.
 RA Mahoney C. W.,
Shuman J., McKnight S. L., Chen H. C., Huang K. P.
 RT Phosphorylation
of CCAAT-enhancer binding protein by protein kinase C
 RT attenuates
site-selective DNA binding
 RL J. Biol. Chem. 267:19396-19403
(1992).
 RN [17]; RE0003024.
 RX MEDLINE; 92269827.

RA Mischoulon D., Rana B., Bucher N. L. R., Farmer S. R.
 RT
Growth-dependent inhibition of CCAAT/enhancer-binding protein
(C/EBPalpha)
 RT gene expression during hepatocyte proliferation
in the regenerating liver
 RT and in culture
 RL Mol. Cell.
Biol. 12:2553-2560 (1992).
 RN [18]; RE0014413.
 RX MEDLINE;
92407038.
 RA Cohn S. M., Simon T. C., Roth K. A., Birkenmeier
E. H., Gordon J. I.
 RT Use of transgenic mice to map cis-acting
elements in the intestinal fatty
 RT acid binding protein gene
(Fabpi) that control its cell lineage-specific
 RT and regional
patterns of expression along the duodenal-colonic and
 RT crypt-villus
axes of the gut epithelium
 RL J. Cell Biol. 119:27-44 (1992).

RN [19]; RE0000015.
 RX MEDLINE; 91128408.
 RA McKeon C.,
Pham T.
 RT Transactivation of the human insulin receptor gene
by the CAAT/enhancer
 RT binding protein
 RL Biochem. Biophys.
Res. Commun. 174:721-728 (1991).
 RN [20]; RE0000504.
 RX
MEDLINE; 92037542.
 RA Samuelsson L., Stroemberg K., Vikman
K., Bjursell G., Enerbaeck S.
 RT The CCAAT/enhancer binding
protein and its role in adipocyte
 RT differentiation: evidence
for direct involvement in terminal adipocyte
 RT development

RL EMBO J. 10:3787-3793 (1991).
 RN [21]; RE0000742.
 RX
MEDLINE; 91357471.
 RA Williams S. C., Cantwell C. A., Johnson
P. F.
 RT A family of C/EBP-related proteins capable of forming
covalently linked
 RT leucine zipper dimers in vitro
 RL
Genes Dev. 5:1553-1567 (1991).
 RN [22]; RE0001003.
 RX
MEDLINE; 91268021.
 RA Stewart M. J., Shean M. L., Paeper B.
W., Duester G.
 RT The role of CCAAT/enhancer-binding protein
in the differential regulation
 RT of a family of human liver
alcohol dehydrogenase genes
 RL J. Biol. Chem. 266:11594-11603
(1991).
 RN [23]; RE0001634.
 RX MEDLINE; 91141497.

RA Pei D., Shih C.
 RT An attenuator domain is sandwiched by
two distinct transactivation domains
 RT in the transcription
factor C/EBP
 RL Mol. Cell. Biol. 11:1480-1487 (1991).

RN [24]; RE0002104.
 RX MEDLINE; 91232900.
 RA Bakker O.,
Parker M. G.
 RT CAAT/enhancer binding protein is able to bind
to ATF/CRE elements
 RL Nucleic Acids Res. 19:1213-1217 (1991).

RN [25]; RE0002479.
 RX MEDLINE; 91219459.
 RA Trujillo
M. A., Letovsky J., Maguire H. F., Lopez-Cabrera M., Siddiqui
A.
 RT Functional analysis of a liver-specific enhancer of
the hepatitis B virus
 RL Proc. Natl. Acad. Sci. USA 88:3797-3801
(1991).
 RN [26]; RE0002649.
 RX MEDLINE; 91102581.

RA Umek R. M., Friedman A. D., McKnight S. L.
 RT CCAAT-enhancer
binding protein: a component of a differentiation switch
 RL
Science 251:288-292 (1991).
 RN [27]; RE0002726.
 RX MEDLINE;
91306473.
 RA Lopez-Cabrera M., Letovsky J., Hu K.-Q., Siddiqui
A.
 RT Transcriptional factor C/EBP binds to and transactivates
the enhancer
 RT element II of the hepatitis B virus
 RL
Virology 183:825-829 (1991).
 RN [28]; RE0000177.
 RX MEDLINE;
91029495.
 RA Poli V., Mancini F. P., Cortese R.
 RT IL-6DBP,
a nuclear protein involved in interleukin-6 signal transduction,

RT defines a new family of leucine zipper proteins related to
C/EBP
 RL Cell 63:643-653 (1990).
 RN [29]; RE0000740.

RX MEDLINE; 91032993.
 RA Friedman A. D., McKnight S. L.

RT Identification of two polypeptide segments of CCAAT/enhancer-binding

RT protein required for transcriptional activation of the serum
albumin gene
 RL Genes Dev. 4:1416-1426 (1990).
 RN [30];
RE0000923.
 RX MEDLINE; 90153995.
 RA Zhang D.-E., Hoyt
P. R., Papaconstantinou J.
 RT Localization of DNA Protein-binding
Sites in the Proximal and Distal
 RT Promoter Regions of the
Mouse alpha-Fetoprotein Gene
 RL J. Biol. Chem. 265:3382-3391
(1990).
 RN [31]; RE0001157.
 RX MEDLINE; 90204660.

RA Pei D., Shih C.
 RT Transcriptional activation and repression
by cellular DNA-binding protein
 RT C/EBP
 RL J. Virol.
64:1517-1522 (1990).
 RN [32]; RE0001369.
 RX MEDLINE; 90220629.

RA Trus M., Benvenisty N., Cohen H., Reshef L.
 RT Developmentally
Regulated Interaction of Liver Nuclear Factors with the Rat

RT Phosphoenolpyruvate Carboxykinase Promoter
 RL Mol. Cell.
Biol. 10:2418-2422 (1990).
 RN [33]; RE0002680.
 RX MEDLINE;
90357025.
 RA Shuman J. D., Vinson C. R., McKnight S. L.

RT Evidence of changes in protease sensitivity and subunit exchange
rate on
 RT DNA binding by C/EBP
 RL Science 249:771-774
(1990).
 RN [34]; RE0002760.
 RX MEDLINE; 90287159.

RA Dikstein R., Faktor O., Ben-Levy R., Shaul Y.
 RT Functional
Organization of the Hepatitis B Virus Enhancer
 RL Mol. Cell.
Biol. 10:3683-3689 (1990).
 RN [35]; RE0003188.
 RX MEDLINE;
90357026.
 RA ONeil K.T., Hoess R.H., DeGrado W.F.
 RT Design
of DNA-binding Peptides Based on the Leucine Zipper Motif

RL Science 249:774-778 (1990).
 RN [36]; RE0000630.
 RX
MEDLINE; 90108682.
 RA Christy R. J., Yang V. W., Ntambi J.
M., Geiman D. E., Landschulz W. H.,
 RA Friedman A. D., Nakabeppu
Y., Kelly T. J., Lane M. D.
 RT Differentiation-induced gene
expression in 3T3-L1 preadipocytes: CCAAT/
 RT enhancer binding
protein interacts with and activates the promoters of two

RT adipocyte-specific genes
 RL Genes Dev. 3:1323-1335 (1989).

RN [37]; RE0000634.
 RX MEDLINE; 90108681.
 RA Friedman
A. D., Landschulz W. H., McKnight S. L.
 RT CCAAT/enhancer
binding protein activates the promoter of the serum albumin

RT gene in cultured hepatoma cells
 RL Genes Dev. 3:1314-1322
(1989).
 RN [38]; RE0000669.
 RX MEDLINE; 90185181.

RA McKnight S. L., Lane M. D., Gluecksohn-Waelsch S.
 RT Is
CCAAT/enhancer-binding protein a central regulator of energy metabolism

RL Genes Dev. 3:2021-2024 (1989).
 RN [39]; RE0000741.

RX MEDLINE; 90006736.
 RA Birkenmeier E. H., Gwynn B., Howard
S., Jerry J., Gordon J. I., Landschulz
 RA W. H., McKnight
S. L.
 RT Tissue-specific expression, developmental regulation,
and genetic mapping
 RT of the gene encoding CCAAT/enhancer
binding protein
 RL Genes Dev. 3:1146-1156 (1989).
 RN [40];
RE0001218.
 RX MEDLINE; 89261719.
 RA Ryden T. A., Beemon
K.
 RT Avian Retroviral Long Terminal Repeats Bind CCAAT/Enhancer-Binding
Protein
 RL Mol. Cell. Biol. 9:1155-1164 (1989).
 RN [41];
RE0001427.
 RX MEDLINE; 89384552.
 RA Howell B. W., Lagace
M., Shore M. C.
 RT Activity of the Carbamyl Phosphate Synthetase
I Promoter in Liver Nuclear
 RT Extracts is Dependent on a
cis-Acting C/EBP Recognition Element
 RL Mol. Cell. Biol. 9:2928-2933
(1989).
 RN [42]; RE0002265.
 RX MEDLINE; 89160814.

RA Herbst R. S., Friedman N., Darnell J. E., Babiss L. E.

RT Positive and negative regulatory elements in the mouse albumin
enhancer
 RL Proc. Natl. Acad. Sci. USA 86:1553-1557 (1989).

RN [43]; RE0002592.
 RX MEDLINE; 90049224.
 RA Vinson C.
R., Sigler P. B., McKnight S. L.
 RT Scissors-grip model for
DNA recognition by a family of leucine zipper
 RT proteins

RL Science 246:911-916 (1989).
 RN [44]; RE0002600.
 RX
MEDLINE; 89186916.
 RA Landschulz W. H., Johnson P. F., McKnight
S. L.
 RT The DNA binding domain of the rat liver nuclear protein
C/EBP is bipartite
 RL Science 243:1681-1688 (1989).
 RN
[45]; RE0003019.
 RX MEDLINE; 89092001.
 RA Landschulz W.
H., Johnson P. F., Adashi E. Y., Graves B. J., McKnight S. L.

RT Isolation of a recombinant copy of the gene encoding C/EBP

RL Genes Dev. 2:786-800 (1988).
 RN [46]; RE0000615.
 RX
MEDLINE; 88056262.
 RA Johnson P. F., Landschulz W. H., Graves
B. J., McKnight S. L.
 RT Identification of a rat liver nuclear
protein that binds to the enhancer
 RT core element of three
animal viruses
 RL Genes Dev. 1:133-146 (1987).
 RN [47];
RE0000115.
 RX MEDLINE; 86133549.
 RA Graves B. J., Johnson
P. F., McKnight S. L.
 RT Homologous recognition of a promoter
domain common to the MSV LTR and the
 RT HSV tk gene
 RL
Cell 44:565-576 (1986).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

208 genes, 208 accessions (Toggle view)

AccessionGeneTitleLinks
MGC40053ARMCX4Armadillo repeat containing, X-linked 4Source|GeneCards
SDFR1SDFR1stromal cell derived factor receptor 1Source|GeneCards
TSGA10TSGA10testis specific, 10Source|GeneCards
H3F3BH3F3BH3 histone, family 3B (H3.3B)Source|GeneCards
CTNNBIP1CTNNBIP1catenin, beta interacting protein 1Source|GeneCards
SOX4SOX4SRY (sex determining region Y)-box 4Source|GeneCards
MEIS1MEIS1Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)Source|GeneCards
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)Source|GeneCards
FKBP3FKBP3FK506 binding protein 3, 25kDaSource|GeneCards
ETF1ETF1eukaryotic translation termination factor 1Source|GeneCards
PLAGL2PLAGL2pleiomorphic adenoma gene-like 2Source|GeneCards
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
SLC24A4SLC24A4solute carrier family 24 (sodium/potassium/calcium exchanger), member 4Source|GeneCards
BDNFBDNFbrain-derived neurotrophic factorSource|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
PIK3C2APIK3C2Aphosphoinositide-3-kinase, class 2, alpha polypeptideSource|GeneCards
NUMA1NUMA1nuclear mitotic apparatus protein 1Source|GeneCards
NUDT3NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 3Source|GeneCards
ACVR1ACVR1activin A receptor, type ISource|GeneCards
GPX1GPX1glutathione peroxidase 1Source|GeneCards
NFX1NFX1nuclear transcription factor, X-box binding 1Source|GeneCards
IL1RAPL2IL1RAPL2interleukin 1 receptor accessory protein-like 2Source|GeneCards
GLRA2GLRA2glycine receptor, alpha 2Source|GeneCards
PTPRUPTPRUprotein tyrosine phosphatase, receptor type, USource|GeneCards
RAB6ARAB6ARAB6A, member RAS oncogene familySource|GeneCards
PLCB2PLCB2phospholipase C, beta 2Source|GeneCards
OSMROSMRoncostatin M receptorSource|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
NUP153NUP153nucleoporin 153kDaSource|GeneCards
RNPC2RNPC2RNA-binding region (RNP1, RRM) containing 2Source|GeneCards
FLJ34870FLJ34870FLJ34870 proteinSource|GeneCards
ROR1ROR1receptor tyrosine kinase-like orphan receptor 1Source|GeneCards
FLJ26184C16ORF47chromosome 16 open reading frame 47Source|GeneCards
ASCL3ASCL3achaete-scute complex (Drosophila) homolog-like 3Source|GeneCards
ADRB2ADRB2adrenergic, beta-2-, receptor, surfaceSource|GeneCards
LRRTM3LRRTM3leucine-rich repeat transmembrane neuronal 3 proteinSource|GeneCards
FLJ35821FLJ35821hypothetical protein FLJ35821Source|GeneCards
TNRC4TNRC4trinucleotide repeat containing 4Source|GeneCards
RPS19RPS19ribosomal protein S19Source|GeneCards
TGM3TGM3transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)Source|GeneCards
GATA4GATA4GATA binding protein 4Source|GeneCards
C6ORF65C6ORF65chromosome 6 open reading frame 65Source|GeneCards
FBXW7FBXW7F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)Source|GeneCards
PLAG1PLAG1pleiomorphic adenoma gene 1Source|GeneCards
SFRS2IPSFRS2IPsplicing factor, arginine/serine-rich 2, interacting proteinSource|GeneCards
FLJ25421FLJ25421hypothetical protein FLJ25421Source|GeneCards
CIP29CIP29cytokine induced protein 29 kDaSource|GeneCards
SCML1SCML1sex comb on midleg-like 1 (Drosophila)Source|GeneCards
IRX6IRX6iroquois homeobox protein 6Source|GeneCards
MAP2K6MAP2K6mitogen-activated protein kinase kinase 6Source|GeneCards
REREREREarginine-glutamic acid dipeptide (RE) repeatsSource|GeneCards
HLX1HLX1H2.0-like homeo box 1 (Drosophila)Source|GeneCards
FLJ45455FLJ45455FLJ45455 proteinSource|GeneCards
ETV1ETV1ets variant gene 1Source|GeneCards
POFUT1POFUT1protein O-fucosyltransferase 1Source|GeneCards
MRPL12MRPL12mitochondrial ribosomal protein L12Source|GeneCards
TAFA1TAFA1TAFA1 proteinSource|GeneCards
PRRG2PRRG2proline-rich Gla (G-carboxyglutamic acid) polypeptide 2Source|GeneCards
CTGFCTGFconnective tissue growth factorSource|GeneCards
NOSIPNOSIPnitric oxide synthase interacting proteinSource|GeneCards
KIAA0157KIAA0157KIAA0157 proteinSource|GeneCards
C6ORF29C6ORF29chromosome 6 open reading frame 29Source|GeneCards
MGC4796STK40serine/threonine kinase 40Source|GeneCards
DLX1DLX1distal-less homeo box 1Source|GeneCards
TP73LTP73Ltumor protein p73-likeSource|GeneCards
MITFMITFmicrophthalmia-associated transcription factorSource|GeneCards
SARSSARSseryl-tRNA synthetaseSource|GeneCards
OVOL1OVOL1ovo-like 1(Drosophila)Source|GeneCards
NDNNDNnecdin homolog (mouse)Source|GeneCards
RNF38RNF38ring finger protein 38Source|GeneCards
NFKBIANFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaSource|GeneCards
MSL3L1MSL3L1male-specific lethal 3-like 1 (Drosophila)Source|GeneCards
LRRTM1LRRTM1leucine-rich repeat transmembrane neuronal 1 proteinSource|GeneCards
LOC163223LOC163223Zinc finger protein 676Source|GeneCards
ALDOAALDOAaldolase A, fructose-bisphosphateSource|GeneCards
KLF5KLF5Kruppel-like factor 5 (intestinal)Source|GeneCards
IRLBMYCPBPc-myc promoter binding proteinSource|GeneCards
P2RY1P2RY1purinergic receptor P2Y, G-protein coupled, 1Source|GeneCards
APCAPCadenomatosis polyposis coliSource|GeneCards
FOXO3AFOXO3Aforkhead box O3ASource|GeneCards
HYPKHYPKHuntingtin interacting protein KSource|GeneCards
UNQ689UNQ689RSTI689Source|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
FLJ44048FLJ44048FLJ44048 proteinSource|GeneCards
CHD6CHD6chromodomain helicase DNA binding protein 6Source|GeneCards
PRG4PRG4proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)Source|GeneCards
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)Source|GeneCards
NEUROD1NEUROD1neurogenic differentiation 1Source|GeneCards
SAV1SAV1salvador homolog 1 (Drosophila)Source|GeneCards
RGS8RGS8regulator of G-protein signalling 8Source|GeneCards
RAD23BRAD23BRAD23 homolog B (S. cerevisiae)Source|GeneCards
TGFB1I4TSC22D1TSC22 domain family, member 1Source|GeneCards
FLJ14957CGNL1cingulin-like 1Source|GeneCards
EPC2EPC2enhancer of polycomb homolog 2 (Drosophila)Source|GeneCards
PER1PER1period homolog 1 (Drosophila)Source|GeneCards
LOC151534LOC151534hypothetical protein BC009264Source|GeneCards
GPLD1GPLD1glycosylphosphatidylinositol specific phospholipase D1Source|GeneCards
PTAFRPTAFRplatelet-activating factor receptorSource|GeneCards
DNCLI2DNCLI2dynein, cytoplasmic, light intermediate polypeptide 2Source|GeneCards
MAS1LMAS1LMAS1 oncogene-likeSource|GeneCards
RNF39RNF39ring finger protein 39Source|GeneCards
DCNDCNdecorinSource|GeneCards
DLG2DLG2Discs, large homolog 2, chapsyn-110 (Drosophila)Source|GeneCards
TUBA3TUBA3tubulin, alpha 3Source|GeneCards
WNT10BWNT10Bwingless-type MMTV integration site family, member 10BSource|GeneCards
DDR2DDR2discoidin domain receptor family, member 2Source|GeneCards
RELARELAv-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)Source|GeneCards
DKFZP686L1814DKFZP686L1814hypothetical protein DKFZp686L1814Source|GeneCards
BCL2L13BCL2L13BCL2-like 13 (apoptosis facilitator)Source|GeneCards
CREB5CREB5cAMP responsive element binding protein 5Source|GeneCards
FGF12FGF12fibroblast growth factor 12Source|GeneCards
HS747E2AHS747E2Ahypothetical protein HS747E2ASource|GeneCards
CA3CA3carbonic anhydrase III, muscle specificSource|GeneCards
ITPK1ITPK1inositol 1,3,4-triphosphate 5/6 kinaseSource|GeneCards
RHOQRHOQras homolog gene family, member QSource|GeneCards
MGC4562MGC4562hypothetical protein MGC4562Source|GeneCards
ACSL5ACSL5acyl-CoA synthetase long-chain family member 5Source|GeneCards
IL1RAPL1IL1RAPL1interleukin 1 receptor accessory protein-like 1Source|GeneCards
RORARORARAR-related orphan receptor ASource|GeneCards
PLA2G4APLA2G4Aphospholipase A2, group IVA (cytosolic, calcium-dependent)Source|GeneCards
ZCCHC5ZCCHC5zinc finger, CCHC domain containing 5Source|GeneCards
RRM1RRM1ribonucleotide reductase M1 polypeptideSource|GeneCards
PTPN12PTPN12protein tyrosine phosphatase, non-receptor type 12Source|GeneCards
TNNC2TNNC2troponin C2, fastSource|GeneCards
C18ORF21C18ORF21chromosome 18 open reading frame 21Source|GeneCards
LTBLTBlymphotoxin beta (TNF superfamily, member 3)Source|GeneCards
ZNFN1A4ZNFN1A4zinc finger protein, subfamily 1A, 4 (Eos)Source|GeneCards
HSD11B1HSD11B1hydroxysteroid (11-beta) dehydrogenase 1Source|GeneCards
AP1S2AP1S2adaptor-related protein complex 1, sigma 2 subunitSource|GeneCards
RLFRLFRearranged L-myc fusionSource|GeneCards
TM4SF2TM4SF2transmembrane 4 superfamily member 2Source|GeneCards
CHATCHATCholine acetyltransferaseSource|GeneCards
FLJ90805FLJ90805hypothetical protein FLJ90805Source|GeneCards
CHD2CHD2chromodomain helicase DNA binding protein 2Source|GeneCards
ZNF403ZNF403zinc finger protein 403Source|GeneCards
SEZ6SEZ6seizure related 6 homolog (mouse)Source|GeneCards
NTRK1NTRK1neurotrophic tyrosine kinase, receptor, type 1Source|GeneCards
ZNF137ZNF137zinc finger protein 137 (clone pHZ-30)Source|GeneCards
RAB1ARAB1ARAB1A, member RAS oncogene familySource|GeneCards
LOC286480LOC286480Ubiquitin-conjugating enzyme E2E 4 pseudogeneSource|GeneCards
PROX1PROX1prospero-related homeobox 1Source|GeneCards
MYL1MYL1myosin, light polypeptide 1, alkali; skeletal, fastSource|GeneCards
STC2STC2stanniocalcin 2Source|GeneCards
FLJ12735C17ORF41chromosome 17 open reading frame 41Source|GeneCards
ING3ING3inhibitor of growth family, member 3Source|GeneCards
FSTL1FSTL1follistatin-like 1Source|GeneCards
CHST9CHST9carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9Source|GeneCards
HHLRABGAP1LRAB GTPase activating protein 1-likeSource|GeneCards
RARBRARBretinoic acid receptor, betaSource|GeneCards
OSBPL6OSBPL6oxysterol binding protein-like 6Source|GeneCards
FGF14FGF14fibroblast growth factor 14Source|GeneCards
STAG2STAG2stromal antigen 2Source|GeneCards
GOT1GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)Source|GeneCards
BOCBOCbrother of CDOSource|GeneCards
ELKSRAB6IP2RAB6 interacting protein 2Source|GeneCards
CACNA2D3CACNA2D3calcium channel, voltage-dependent, alpha 2/delta 3 subunitSource|GeneCards
JMJD1CJMJD1Cjumonji domain containing 1CSource|GeneCards
SLC12A1SLC12A1solute carrier family 12 (sodium/potassium/chloride transporters), member 1Source|GeneCards
SERPINB2SERPINB2serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2Source|GeneCards
KIAA0555KIAA0555KIAA0555 gene productSource|GeneCards
A2BP1A2BP1ataxin 2-binding protein 1Source|GeneCards
MGC29649TTC9Ctetratricopeptide repeat domain 9CSource|GeneCards
EHFEHFets homologous factorSource|GeneCards
PHACTR4PHACTR4phosphatase and actin regulator 4Source|GeneCards
GLRA3GLRA3glycine receptor, alpha 3Source|GeneCards
UNG2UNG2uracil-DNA glycosylase 2Source|GeneCards
SLC22A8SLC22A8solute carrier family 22 (organic anion transporter), member 8Source|GeneCards
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptideSource|GeneCards
PRDX6PRDX6peroxiredoxin 6Source|GeneCards
FLJ13842ZMAT4zinc finger, matrin type 4Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
LEMD2LEMD2LEM domain containing 2Source|GeneCards
SUPT4H1SUPT4H1suppressor of Ty 4 homolog 1 (S. cerevisiae)Source|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
ZIC1ZIC1Zic family member 1 (odd-paired homolog, Drosophila)Source|GeneCards
KIAA1747LOC57795hypothetical protein from clone 24828Source|GeneCards
ZIC4ZIC4Zic family member 4Source|GeneCards
SATSATspermidine/spermine N1-acetyltransferaseSource|GeneCards
USP2USP2ubiquitin specific protease 2Source|GeneCards
SLC39A14SLC39A14solute carrier family 39 (zinc transporter), member 14Source|GeneCards
RFX4RFX4regulatory factor X, 4 (influences HLA class II expression)Source|GeneCards
VEGFVEGFvascular endothelial growth factorSource|GeneCards
CRIM1CRIM1cysteine-rich motor neuron 1Source|GeneCards
VNN3VNN3vanin 3Source|GeneCards
C6ORF15C6ORF15chromosome 6 open reading frame 15Source|GeneCards
RASGRP4RASGRP4RAS guanyl releasing protein 4Source|GeneCards
MGC5395MGC5395hypothetical protein MGC5395Source|GeneCards
LOC220074LOC220074Hypothetical 55.1 kDa protein F09G8.5 in chromosome IIISource|GeneCards
MDS018PPCDCphosphopantothenoylcysteine decarboxylaseSource|GeneCards
LUC7LLUC7LLUC7-like (S. cerevisiae)Source|GeneCards
C10ORF81C10ORF81chromosome 10 open reading frame 81Source|GeneCards
MAGED2MAGED2melanoma antigen, family D, 2Source|GeneCards
JUNJUNv-jun sarcoma virus 17 oncogene homolog (avian)Source|GeneCards
ROBO4ROBO4roundabout homolog 4, magic roundabout (Drosophila)Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
SEC14L3SEC14L3SEC14-like 3 (S. cerevisiae)Source|GeneCards
MAP4K4MAP4K4mitogen-activated protein kinase kinase kinase kinase 4Source|GeneCards
KIAA1318RGAG1retrotransposon gag domain containing 1Source|GeneCards
SEMA7ASEMA7Asema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7ASource|GeneCards
FLJ14281DNAJB14DnaJ (Hsp40) homolog, subfamily B, member 14Source|GeneCards
CEBPBCEBPBCCAAT/enhancer binding protein (C/EBP), betaSource|GeneCards
SSX2IPSSX2IPsynovial sarcoma, X breakpoint 2 interacting proteinSource|GeneCards
MAP2K3MAP2K3mitogen-activated protein kinase kinase 3Source|GeneCards
NR1D1NR1D1nuclear receptor subfamily 1, group D, member 1Source|GeneCards
MBNL2MBNL2muscleblind-like 2 (Drosophila)Source|GeneCards
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1Source|GeneCards
CACNG2CACNG2calcium channel, voltage-dependent, gamma subunit 2Source|GeneCards

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