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Gene set: V$E2F1_Q3_01 (C3:TFAC:0425)
Standard nameV$E2F1_Q3_01
Systematic nameC3:TFAC:0425
Brief descriptionGenes with 3'UTR containing motif TTGGCGCGRAANNGNM which matches annotation for E2F1: E2F transcription factor 1
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA E2F-1
 XX
 SY RBB3.
 XX
 OS
human, Homo sapiens
 OC eukaryota; animalia; metazoa; chordata;
vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0023; fork head; 3.3.3.1.1.
 XX
 SZ 437
AA; 46.9 kDa (cDNA), 54 kDa (SDS) [21] [20], 60 kDa (SDS) [17]
[18]
 XX
 XX
 SC SwissProt #Q01094
 XX
 FT 1 124
cyclin A/cdk2 binding.
 FT 89 184 DNA-binding domain.
 FT
109 127 basic region.
 FT 123 338 PF02319; E2F_TDP.
 FT
128 181 potential helix-loop-helix domain.
 FT 128 142 helix
I.
 FT 150 191 dimerization domain.
 FT 156 181 helix II.

FT 199 234 potential leucine zipper (VL3CL).
 FT 368 437 transcription
activating region.
 FT 409 426 Rb-binding region.
 XX

SF homo- and heterodimerizes, heterodimers with DP-1 (= E2F activity)
show
 SF enhanced DNA- and Rb-binding;
 SF heterodimerization
with DP-1 depends on an intact zipper motif [16];
 SF prior
to crystal structure belongs to bHLH-zip factors [2];
 SF also
binds cyclinA/cdk2, but not the individual subunits [5];
 SF
the Rb-binding region also contacts TBP [15];
 XX
 FF E2F-1
contributes the transcriptional activation domain to E2F-1/DP-1

FF heterodimers (E2F) [17] [18];
 FF overexpression may cause
neoplastic transformation [8];
 FF deregulated function in
cooperation with ras causes oncogenic
 FF transformation [14];

FF autoregulates its own promoter in a cell cycle-dependent manner
[6] [10]
 FF [12];
 FF binding of Rb masks the transcription
activation region and prevents it
 FF from interacting with
TBP [15];
 FF phosphorylation at Ser-332 and Ser-337 at the
end of G1 phase, presumably
 FF by cdc2 or cdk2, inhibits Rb
binding [7], inhibits DNA-binding by a
 FF E2F-1/cyclin A/cdk2
complex [5] [9] [13], largely enhances interaction with
 FF
adenoviral E4 [7];
 FF no phosphorylation by cyclin E/cdk2
[9];
 FF expression of E2F-1 activity is lost upon senescence
of cells [11];
 FF E2F-1 regulates the expression of Apaf-1,
the gene for apoptosis
 FF protease-activating factor 1;

FF provides a direct link between the deregulation of the pRB
pathway and
 FF apoptosis [1];
 FF expression is up-regulated
in G1/S phase transition and during S phase in
 FF T-cells,
where E2F-1 is predominantly present in a free form without bound

FF regulatory protein (pRb) [4];
 XX
 IN T03240; DDB; human,
Homo sapiens.
 IN T01548; DP-1; human, Homo sapiens.
 IN
T01549; DP-1; mouse, Mus musculus.
 IN T03000; DP-2; human,
Homo sapiens.
 IN T01542; E2F-1; human, Homo sapiens.
 IN
T01544; E2F-2; human, Homo sapiens.
 IN T00671; p53; human,
Homo sapiens.
 IN T00722; pRb; human, Homo sapiens.
 IN
T00794; TBP; human, Homo sapiens.
 XX
 XX
 XX
 XX

RN [1]; RE0016344.
 RX MEDLINE; 21283226.
 RA Moroni M.
C., Hickman E. S., Denchi E. L., Caprara G., Colli E., Cecconi

RA F., Muller H., Helin K.
 RT Apaf-1 is a transcriptional
target for E2F and p53.
 RL Nat. Cell Biol. 3:552-558 (2001).

RN [2]; RE0015322.
 RX MEDLINE; 99190701.
 RA Zheng N.,
Fraenkel E., Pabo C. O., Pavletich N. P.
 RT Structural basis
of DNA recognition by the heterodimeric cell cycle
 RT transcription
factor E2F-DP
 RL Genes Dev. 13:666-674 (1999).
 RN [3];
RE0014167.
 RX MEDLINE; 98078680.
 RA Hayes S., Shiyanov
P., Chen X., Raychaudhuri P.
 RT DDB, a putative DNA repair
protein, can function as a transcriptional
 RT partner of E2F1

RL Mol. Biol. Cell 18:240-249 (1998).
 RN [4]; RE0012605.

RX MEDLINE; 96239498.
 RA Moberg K., Starz M. A., Lees J. A.

RT E2F-4 switches from p130 to p107 and pRB in response to cell
cycle reentry
 RL Mol. Cell. Biol. 16:1436-1449 (1996).

RN [5]; RE0003299.
 RX MEDLINE; 95059071.
 RA Xu M., Sheppard
K. A., Peng C.-Y., Yee A. S., Piwnica-Worms H.
 RT Cyclin A/CDK2
binds directly to E2F-1 and inhibits the DNA-binding activity

RT of E2F-1/DP-1 by phosphorylation
 RL Mol. Cell. Biol. 14:8420-8431
(1994).
 RN [6]; RE0003306.
 RX MEDLINE; 95021188.
 RA
Neuman E., Flemington E. K., Sellers W. R., Kaelin jr W. G.

RT Transcription of the E2F-1 gene is rendered cell cycle dependent
by E2F
 RT DNA-binding sites within its promoter
 RL Mol.
Cell. Biol. 14:6607-6615 (1994).
 RN [7]; RE0003308.
 RX
MEDLINE; 94373816.
 RA Fagan R., Flint K. J., Jones N.

RT Phosphorylation of E2F-1 modulates its interaction with the
retinoblastoma
 RT gene product and the adenoviral E4 19 kDa
protein
 RL Cell 78:799-811 (1994).
 RN [8]; RE0003309.

RX MEDLINE; 94320597.
 RA Singh P., Wong S. H., Hong W.

RT Overexpression of E2F-1 in rat embryo fibroblasts leads to
neoplastic
 RT transformation
 RL EMBO J. 13:3329-3338 (1994).

RN [9]; RE0003310.
 RX MEDLINE; 95047332.
 RA Dynlacht B.
D., Flores O., Lees J. A., Harlow E.
 RT Differential regulation
of E2F trans-activation by cyclin/cdk2 complexes
 RL Genes
Dev. 8:1772-1786 (1994).
 RN [10]; RE0003311.
 RX MEDLINE;
95047312.
 RA Hsiao K. M., McMahon S. L., Farnham P. J.

RT Multiple DNA elements are required for the growth regulation
of the mouse
 RT E2F1 promoter
 RL Genes Dev. 8:1526-1537
(1994).
 RN [11]; RE0003312.
 RX MEDLINE; 94266806.

RA Dimri G. P., Hara E., Campisi J.
 RT Regulation of two E2F-related
genes in presenescent and senescent human
 RT fibroblasts

RL J. Biol. Chem. 269:16180-16186 (1994).
 RN [12]; RE0003313.

RX MEDLINE; 95047311.
 RA Johnson D. G., Ohtani K., Nevins
J. R.
 RT Autoregulatory control of E2F1 expression in response
to positive and
 RT negative regulators of cell cycle progression

RL Genes Dev. 8:1514-1525 (1994).
 RN [13]; RE0003314.

RX MEDLINE; 94306513.
 RA Krek W., Ewen M. E., Shirodkar S.,
Arany Z., Kaelin jr W. G., Livingston D.
 RA M.
 RT Negative
regulation of the growth-promoting transcription factor E2F-1
by a
 RT stably bound cyclin A-dependent protein kinase

RL Cell 78:161-172 (1994).
 RN [14]; RE0003545.
 RX MEDLINE;
95108050.
 RA Johnson D. G., Cress W. D., Jakoi L., Nevins
J. R.
 RT Oncogenic capacity of the E2F1 gene
 RL Proc.
Natl. Acad. Sci. USA 91:12823-12827 (1994).
 RN [15]; RE0003294.

RX MEDLINE; 94077697.
 RA Hagemeier C., Cook A., Kouzarides
T.
 RT The retinoblastoma protein binds E2F residues required
for activation in
 RT vivo and TBP binding in vitro
 RL
Nucleic Acids Res. 21:4998-5004 (1993).
 RN [16]; RE0003300.

RX MEDLINE; 94069342.
 RA Krek W., Livingston D. M., Shirodkar
S.
 RT Binding to DNA and the retinoblastoma gene product promoted
by complex
 RT formation of different E2F family members

RL Science 262:1557-1560 (1993).
 RN [17]; RE0003281.
 RX
MEDLINE; 92346721.
 RA Kaelin W. G., Krek W., Sellers W. R.,
DeCaprio J. A., Ajchenbaum F., fuchs
 RA C. S., Chittenden
T., Blanar M. A., Livingston D. M., Flemington E. K.
 RT Expression
cloning of a cDNA encoding a retinoblastoma-binding protein with

RT E2F-like properties
 RL Cell 70:351-364 (1992).
 RN [18];
RE0003282.
 RX MEDLINE; 92346720.
 RA Helin K., Lees J.
A., Vidal M., Dyson N., Fattaey A.
 RT A cDNA encoding a pRB-binding
protein with properties of the transcription
 RT factor E2F

RL Cell 70:337-350 (1992).
 RN [19]; RE0003284.
 RX MEDLINE;
93078763.
 RA Shan B., Zhu X., Chen P.-L., Durfee T., Yang
Y., Sharp D., Lee W.-H.
 RT Molecular cloning of cellular genes
encoding retinoblastoma-associated
 RT proteins: identification
of a gene with properties of the transcription
 RT factor E2F

RL Mol. Cell. Biol. 12:5620-5631 (1992).
 RN [20]; RE0000163.

RX MEDLINE; 91256306.
 RA Chellappan S. P., Hiebert S., Mudryj
M., Horowitz J. M., Nevins J. R.
 RT The E2F transcription
factor is a cellular target for the RB protein
 RL Cell 65:1053-1061
(1991).
 RN [21]; RE0001236.
 RX MEDLINE; 89219051.

RA Yee A. S., Raychaudhuri P., Jakoi L., Nevins J. R.
 RT The
Adenovirus-Inducible Factor E2F Stimulates Transcription after
Specific
 RT DNA Binding
 RL Mol. Cell. Biol. 9:578-585
(1989).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

254 genes, 254 accessions (Toggle view)

AccessionGeneTitleLinks
EGR3EGR3early growth response 3Source|GeneCards
CDK6CDK6cyclin-dependent kinase 6Source|GeneCards
APOEAPOEapolipoprotein ESource|GeneCards
MSI1MSI1musashi homolog 1 (Drosophila)Source|GeneCards
MEIS1MEIS1Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)Source|GeneCards
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)Source|GeneCards
TLK2TLK2tousled-like kinase 2Source|GeneCards
ARHGEF12ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12Source|GeneCards
GGA1GGA1golgi associated, gamma adaptin ear containing, ARF binding protein 1Source|GeneCards
CDK9CDK9cyclin-dependent kinase 9 (CDC2-related kinase)Source|GeneCards
FKBP2FKBP2FK506 binding protein 2, 13kDaSource|GeneCards
SLC25A11SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11Source|GeneCards
TLE3TLE3transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)Source|GeneCards
SIAT9SIAT9sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)Source|GeneCards
PLK4PLK4polo-like kinase 4 (Drosophila)Source|GeneCards
NKX6-2NKX6-2NK6 transcription factor related, locus 2 (Drosophila)Source|GeneCards
BHC80PHF21APHD finger protein 21ASource|GeneCards
FLJ20257BCDIN3bin3, bicoid-interacting 3, homolog (Drosophila)Source|GeneCards
CTDSP1CTDSP1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1Source|GeneCards
POLR1DPOLR1Dpolymerase (RNA) I polypeptide D, 16kDaSource|GeneCards
MEIS2MEIS2Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)Source|GeneCards
TMEM25TMEM25Transmembrane protein 25Source|GeneCards
SCA1ATXN1ataxin 1Source|GeneCards
DD5EDD1E3 ubiquitin protein ligase, HECT domain containing, 1Source|GeneCards
RANBP1RANBP1RAN binding protein 1Source|GeneCards
ZNF318ZNF318zinc finger protein 318Source|GeneCards
MLL5MLL5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)Source|GeneCards
GMNNGMNNgeminin, DNA replication inhibitorSource|GeneCards
YWHAQYWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptideSource|GeneCards
IRF2BP1IRF2BP1interferon regulatory factor 2 binding protein 1Source|GeneCards
ITPKAITPKAinositol 1,4,5-trisphosphate 3-kinase ASource|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
PTPRUPTPRUprotein tyrosine phosphatase, receptor type, USource|GeneCards
ARXARXaristaless related homeoboxSource|GeneCards
DUSP6DUSP6dual specificity phosphatase 6Source|GeneCards
UNC13BUNC13Bunc-13 homolog B (C. elegans)Source|GeneCards
DKFZP566M1046DKFZP566M1046hypothetical protein DKFZp566M1046Source|GeneCards
PHF12PHF12PHD finger protein 12Source|GeneCards
RECKRECKreversion-inducing-cysteine-rich protein with kazal motifsSource|GeneCards
EIF5EIF5eukaryotic translation initiation factor 5Source|GeneCards
PPP1CCPPP1CCprotein phosphatase 1, catalytic subunit, gamma isoformSource|GeneCards
EZH2EZH2enhancer of zeste homolog 2 (Drosophila)Source|GeneCards
MRC2MRC2mannose receptor, C type 2Source|GeneCards
ROR1ROR1receptor tyrosine kinase-like orphan receptor 1Source|GeneCards
C10ORF119C10ORF119chromosome 10 open reading frame 119Source|GeneCards
PRIM1PRIM1primase, polypeptide 1, 49kDaSource|GeneCards
P2RY2P2RY2purinergic receptor P2Y, G-protein coupled, 2Source|GeneCards
CALM2CALM2calmodulin 2 (phosphorylase kinase, delta)Source|GeneCards
FXR2FXR2fragile X mental retardation, autosomal homolog 2Source|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
EDG5EDG5endothelial differentiation, sphingolipid G-protein-coupled receptor, 5Source|GeneCards
RAB2RAB2RAB2, member RAS oncogene familySource|GeneCards
MGC2941PHF23PHD finger protein 23Source|GeneCards
C19ORF26C19ORF26chromosome 19 open reading frame 26Source|GeneCards
C9ORF25C9ORF25chromosome 9 open reading frame 25Source|GeneCards
EIF4G1EIF4G1eukaryotic translation initiation factor 4 gamma, 1Source|GeneCards
NEUROD2NEUROD2neurogenic differentiation 2Source|GeneCards
DKFZP566H073RNF167ring finger protein 167Source|GeneCards
LOC51315LOC51315hypothetical protein LOC51315Source|GeneCards
LMX1BLMX1BLIM homeobox transcription factor 1, betaSource|GeneCards
PRO0149PRO0149PRO0149 proteinSource|GeneCards
XTP3TPAXTP3TPAXTP3-transactivated protein ASource|GeneCards
SHFM3FBXW4F-box and WD-40 domain protein 4Source|GeneCards
SENP3SENP3sentrin/SUMO-specific protease 3Source|GeneCards
HIST1H2BKHIST1H2BKhistone 1, H2bkSource|GeneCards
POMZP3POMZP3POM (POM121 homolog, rat) and ZP3 fusionSource|GeneCards
FLJ44313FLJ44313FLJ44313 proteinSource|GeneCards
DUSP7DUSP7dual specificity phosphatase 7Source|GeneCards
EDEM1EDEM1ER degradation enhancer, mannosidase alpha-like 1Source|GeneCards
MGC9850MGC9850hypothetical protein MGC9850Source|GeneCards
NRGNNRGNneurogranin (protein kinase C substrate, RC3)Source|GeneCards
LHX2LHX2LIM homeobox 2Source|GeneCards
TPK1TPK1thiamin pyrophosphokinase 1Source|GeneCards
TPBGTPBGtrophoblast glycoproteinSource|GeneCards
LRP8LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptorSource|GeneCards
HTF9CHTF9CHpaII tiny fragments locus 9CSource|GeneCards
FBXO9FBXO9F-box only protein 9Source|GeneCards
NCAM1NCAM1neural cell adhesion molecule 1Source|GeneCards
VAX1VAX1ventral anterior homeobox 1Source|GeneCards
MGC29814MGC29814hypothetical protein MGC29814Source|GeneCards
ZBTB12ZBTB12zinc finger and BTB domain containing 12Source|GeneCards
RAD23ARAD23ARAD23 homolog A (S. cerevisiae)Source|GeneCards
CLPTM1CLPTM1cleft lip and palate associated transmembrane protein 1Source|GeneCards
GNB2GNB2guanine nucleotide binding protein (G protein), beta polypeptide 2Source|GeneCards
ARHGEF19ARHGEF19Rho guanine nucleotide exchange factor (GEF) 19Source|GeneCards
HMBSHMBShydroxymethylbilane synthaseSource|GeneCards
HSYNRIC8Bresistance to inhibitors of cholinesterase 8 homolog B (C. elegans)Source|GeneCards
ITGA3ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)Source|GeneCards
KPNB1KPNB1karyopherin (importin) beta 1Source|GeneCards
POLAPOLApolymerase (DNA directed), alphaSource|GeneCards
YT521YT521splicing factor YT521-BSource|GeneCards
DDX50DDX50DEAD (Asp-Glu-Ala-Asp) box polypeptide 50Source|GeneCards
ZNF521ZNF521zinc finger protein 521Source|GeneCards
SNF1LKSNF1LKSNF1-like kinaseSource|GeneCards
KIAA0101KIAA0101KIAA0101 gene productSource|GeneCards
FUT8FUT8fucosyltransferase 8 (alpha (1,6) fucosyltransferase)Source|GeneCards
MGC24665MGC24665hypothetical protein MGC24665Source|GeneCards
HBXAPHBXAPhepatitis B virus x associated proteinSource|GeneCards
SFRS7SFRS7splicing factor, arginine/serine-rich 7, 35kDaSource|GeneCards
HRHRhairless homolog (mouse)Source|GeneCards
ELMO2ELMO2engulfment and cell motility 2 (ced-12 homolog, C. elegans)Source|GeneCards
ELK3ELK3ELK3, ETS-domain protein (SRF accessory protein 2)Source|GeneCards
YTHDF2YTHDF2YTH domain family, member 2Source|GeneCards
HMGN2HMGN2high-mobility group nucleosomal binding domain 2Source|GeneCards
CGGBP1CGGBP1CGG triplet repeat binding protein 1Source|GeneCards
DHHDHHdesert hedgehog homolog (Drosophila)Source|GeneCards
LNX2LNX2ligand of numb-protein X 2Source|GeneCards
INSM1INSM1insulinoma-associated 1Source|GeneCards
FOXO3AFOXO3Aforkhead box O3ASource|GeneCards
SIAHBP1SIAHBP1fuse-binding protein-interacting repressorSource|GeneCards
TOPBP1TOPBP1topoisomerase (DNA) II binding proteinSource|GeneCards
LOC130617LOC130617hypothetical protein BC018415Source|GeneCards
SSR4SSR4signal sequence receptor, delta (translocon-associated protein delta)Source|GeneCards
BRAFBRAFv-raf murine sarcoma viral oncogene homolog B1Source|GeneCards
C6ORF89C6ORF89chromosome 6 open reading frame 89Source|GeneCards
KLF4KLF4Kruppel-like factor 4 (gut)Source|GeneCards
PSCD2PSCD2pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)Source|GeneCards
DNAJC9DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 9Source|GeneCards
CENPBCENPBcentromere protein B, 80kDaSource|GeneCards
PCSK4PCSK4proprotein convertase subtilisin/kexin type 4Source|GeneCards
MAML1MAML1mastermind-like 1 (Drosophila)Source|GeneCards
CPNE5CPNE5copine VSource|GeneCards
LOC338692LOC338692hypothetical protein LOC338692Source|GeneCards
RELNRELNreelinSource|GeneCards
IDH3GIDH3Gisocitrate dehydrogenase 3 (NAD+) gammaSource|GeneCards
CXORF12CXORF12chromosome X open reading frame 12Source|GeneCards
VAMP3VAMP3vesicle-associated membrane protein 3 (cellubrevin)Source|GeneCards
NRG2NRG2neuregulin 2Source|GeneCards
ADAM23ADAM23ADAM metallopeptidase domain 23Source|GeneCards
RASD2RASD2RASD family, member 2Source|GeneCards
EN1EN1engrailed homolog 1Source|GeneCards
KCNA1KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)Source|GeneCards
XPR1XPR1xenotropic and polytropic retrovirus receptorSource|GeneCards
FGF11FGF11fibroblast growth factor 11Source|GeneCards
ARPC5LARPC5Lactin related protein 2/3 complex, subunit 5-likeSource|GeneCards
MAZMAZMYC-associated zinc finger protein (purine-binding transcription factor)Source|GeneCards
ARNTLARNTLaryl hydrocarbon receptor nuclear translocator-likeSource|GeneCards
TTC17TTC17Tetratricopeptide repeat domain 17Source|GeneCards
BRMS1LBRMS1Lbreast cancer metastasis-suppressor 1-likeSource|GeneCards
SLITRK3SLITRK3SLIT and NTRK-like family, member 3Source|GeneCards
LYL1LYL1lymphoblastic leukemia derived sequence 1Source|GeneCards
DLEU1DLEU1deleted in lymphocytic leukemia, 1Source|GeneCards
NR2E1NR2E1nuclear receptor subfamily 2, group E, member 1Source|GeneCards
MYCMYCV-myc myelocytomatosis viral oncogene homolog (avian)Source|GeneCards
ID3ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix proteinSource|GeneCards
DLEU2DLEU2deleted in lymphocytic leukemia, 2Source|GeneCards
FLJ13491FLJ13491hypothetical protein FLJ13491Source|GeneCards
TIEGKLF10Kruppel-like factor 10Source|GeneCards
ZNF262ZNF262zinc finger protein 262Source|GeneCards
STAG1STAG1Stromal antigen 1Source|GeneCards
UNQ470UNQ470GAAI470Source|GeneCards
DCKDCKdeoxycytidine kinaseSource|GeneCards
HS6ST2HS6ST2heparan sulfate 6-O-sulfotransferase 2Source|GeneCards
CAM-KIINCAMK2N2calcium/calmodulin-dependent protein kinase II inhibitor 2Source|GeneCards
TNPO3TNPO3transportin 3Source|GeneCards
OSBPL7OSBPL7oxysterol binding protein-like 7Source|GeneCards
JUNBJUNBjun B proto-oncogeneSource|GeneCards
NONONONOnon-POU domain containing, octamer-bindingSource|GeneCards
SATB1SATB1special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)Source|GeneCards
HNRPUL1HNRPUL1heterogeneous nuclear ribonucleoprotein U-like 1Source|GeneCards
PSMD2PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2Source|GeneCards
ZFP36L2ZFP36L2zinc finger protein 36, C3H type-like 2Source|GeneCards
SLC12A5SLC12A5solute carrier family 12, (potassium-chloride transporter) member 5Source|GeneCards
TJP4TJP4tight junction protein 4 (peripheral)Source|GeneCards
KLHL11KLHL11kelch-like 11 (Drosophila)Source|GeneCards
GSPT1GSPT1G1 to S phase transition 1Source|GeneCards
ANKRD13ANKRD13ankyrin repeat domain 13Source|GeneCards
LGALS1LGALS1lectin, galactoside-binding, soluble, 1 (galectin 1)Source|GeneCards
MCM7MCM7MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)Source|GeneCards
MAP1AMAP1Amicrotubule-associated protein 1ASource|GeneCards
DNAJC11DNAJC11DnaJ (Hsp40) homolog, subfamily C, member 11Source|GeneCards
STAG2STAG2stromal antigen 2Source|GeneCards
MARCKSMARCKSmyristoylated alanine-rich protein kinase C substrateSource|GeneCards
ALDH6A1ALDH6A1aldehyde dehydrogenase 6 family, member A1Source|GeneCards
CDKN1CCDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)Source|GeneCards
C20ORF104PHF20PHD finger protein 20Source|GeneCards
MGC40107MGC40107hypothetical protein MGC40107Source|GeneCards
SATB2SATB2SATB family member 2Source|GeneCards
GTF2A1GTF2A1general transcription factor IIA, 1, 19/37kDaSource|GeneCards
NR2F2NR2F2Nuclear receptor subfamily 2, group F, member 2Source|GeneCards
RBL1RBL1retinoblastoma-like 1 (p107)Source|GeneCards
SPOCK2SPOCK2sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2Source|GeneCards
FLJ20487FLJ20487hypothetical protein FLJ20487Source|GeneCards
LOC148872LOC148872LOC148872 proteinSource|GeneCards
PVRL1PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin)Source|GeneCards
LOC286016LOC286016hypothetical protein LOC286016Source|GeneCards
AK2AK2adenylate kinase 2Source|GeneCards
IGSF4IGSF4immunoglobulin superfamily, member 4Source|GeneCards
FGF13FGF13fibroblast growth factor 13Source|GeneCards
PELI2PELI2pellino homolog 2 (Drosophila)Source|GeneCards
DKFZP434B168C1ORF73chromosome 1 open reading frame 73Source|GeneCards
FOSL1FOSL1FOS-like antigen 1Source|GeneCards
HOXA13HOXA13homeo box A13Source|GeneCards
PRDM16PRDM16PR domain containing 16Source|GeneCards
ZNF367ZNF367zinc finger protein 367Source|GeneCards
ABI2ABI2abl interactor 2Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
FLJ90024FLJ90024fasting-inducible integral membrane protein TM6P1Source|GeneCards
TRIM39TRIM39tripartite motif-containing 39Source|GeneCards
DNMT1DNMT1DNA (cytosine-5-)-methyltransferase 1Source|GeneCards
MLLT6MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6Source|GeneCards
HIST1H2AHHIST1H2AHhistone 1, H2ahSource|GeneCards
SLC25A28SLC25A28solute carrier family 25, member 28Source|GeneCards
ISL1ISL1ISL1 transcription factor, LIM/homeodomain, (islet-1)Source|GeneCards
DCAMKL1DCAMKL1doublecortin and CaM kinase-like 1Source|GeneCards
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2ASource|GeneCards
NTN1NTN1netrin 1Source|GeneCards
CDC25ACDC25Acell division cycle 25ASource|GeneCards
USP2USP2ubiquitin specific protease 2Source|GeneCards
C9ORF37C9ORF37chromosome 9 open reading frame 37Source|GeneCards
AP4M1AP4M1adaptor-related protein complex 4, mu 1 subunitSource|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
KCNH5KCNH5potassium voltage-gated channel, subfamily H (eag-related), member 5Source|GeneCards
ZNF565ZNF565zinc finger protein 565Source|GeneCards
FLJ30296PTCHD1Patched domain containing 1Source|GeneCards
AXIN2AXIN2axin 2 (conductin, axil)Source|GeneCards
KLF13KLF13Kruppel-like factor 13Source|GeneCards
TEBPTITF1thyroid transcription factor 1Source|GeneCards
SMARCA1SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1Source|GeneCards
ATAD2ATAD2ATPase family, AAA domain containing 2Source|GeneCards
TCF15TCF15transcription factor 15 (basic helix-loop-helix)Source|GeneCards
C19ORF4C19ORF4chromosome 19 open reading frame 4Source|GeneCards
WEE1WEE1WEE1 homolog (S. pombe)Source|GeneCards
TRPM7TRPM7transient receptor potential cation channel, subfamily M, member 7Source|GeneCards
UHRF2UHRF2ubiquitin-like, containing PHD and RING finger domains, 2Source|GeneCards
SYT6SYT6synaptotagmin VISource|GeneCards
FLJ12529FLJ12529pre-mRNA cleavage factor I, 59 kDa subunitSource|GeneCards
TRPS1TRPS1trichorhinophalangeal syndrome ISource|GeneCards
ARHNARHNras homolog gene family, member NSource|GeneCards
HNRPDHNRPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)Source|GeneCards
NICE-3C1ORF43chromosome 1 open reading frame 43Source|GeneCards
EIF5AEIF5Aeukaryotic translation initiation factor 5ASource|GeneCards
E2F1E2F1E2F transcription factor 1Source|GeneCards
KCND3KCND3potassium voltage-gated channel, Shal-related subfamily, member 3Source|GeneCards
EIF1AYEIF1AYeukaryotic translation initiation factor 1A, Y-linkedSource|GeneCards
SLC35D1SLC35D1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1Source|GeneCards
ZCWPW1ZCWPW1zinc finger, CW-type with PWWP domain 1Source|GeneCards
APXLAPXLapical protein-like (Xenopus laevis)Source|GeneCards
KCNB2KCNB2potassium voltage-gated channel, Shab-related subfamily, member 2Source|GeneCards
MLR2MLR2ligand-dependent corepressorSource|GeneCards
BRUNOL4BRUNOL4bruno-like 4, RNA binding protein (Drosophila)Source|GeneCards
FLJ33207KYkyphoscoliosis peptidaseSource|GeneCards
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3Source|GeneCards
ELYSAHCTF1AT hook containing transcription factor 1Source|GeneCards
RAMPZNF198zinc finger protein 198Source|GeneCards
PPP1CAPPP1CAprotein phosphatase 1, catalytic subunit, alpha isoformSource|GeneCards
STMN1STMN1stathmin 1/oncoprotein 18Source|GeneCards
GABPB2GABPB2GA binding protein transcription factor, beta subunit 2, 47kDaSource|GeneCards
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5Source|GeneCards
ABCB9ABCB9ATP-binding cassette, sub-family B (MDR/TAP), member 9Source|GeneCards
FLJ37478FLJ37478hypothetical protein FLJ37478Source|GeneCards
FOSL2FOSL2FOS-like antigen 2Source|GeneCards
PTD015PTD015PTD015 proteinSource|GeneCards
IMPDH2IMPDH2IMP (inosine monophosphate) dehydrogenase 2Source|GeneCards

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