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Gene set: V$E47_01 (C3:TFAC:0002)
Standard nameV$E47_01
Systematic nameC3:TFAC:0002
Brief descriptionGenes with 3'UTR containing motif VSNGCAGGTGKNCNN which matches annotation for TCF3: Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
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FA E47
XX
SY BCF-1; E2A.E47; E2A-E47; E47; IEBP1 (rat); E2A.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; primates
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XX
CL C0010; bHLH; 1.2.1.0.1.2.
XX
SZ 651 AA; 67.3 kDa (cDNA)
XX
XX
SC reconstituted from hE12 (common N- and C-termini) and conceptually
SC translated fragments from EMBL/GenBank/DDBJ #M65214 and #M24404
XX
FT 1 83 trans-activation domain [4].
FT 345 408 trans-activation domain [4].
FT 397 425 leucine repeat (L2TL2).
FT 547 556 basic region.
FT 547 600 PF00010; HLH.
FT 552 605 SM00353; HLH.
FT 557 600 helix-loop-helix domain.
FT 560 577 Helix 1.
FT 578 584 Loop.
XX
SF basic region contacts DNA, HLH domain is the dimerization interface [18];
SF binds DNA avidly as homodimer (contrasting to E12), or as heterodimer [8];
SF from crystal structure: dimerization domain forms a parallel
SF four-helix-bundle [3];
SF helix 1 is one turn longer than in other bHLH proteins and does not
SF terminate with a proline, the additional turn allowing a salt bridge to
SF form between H576 (at the end of helix 1) and E600 of helix 2 of the other
SF E47 peptide [3];
SF trans-activation domain is identical with that of E12;
SF that around 345-408 is targeted by the bZIP of c-Jun when repressing
SF activation by E2A proteins [1];
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CP ubiquitous
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FF part of MEF-1 complex;
FF induces hyperphosphorylation of MyoD upon association;
FF induces transcription of IgH, but also of IgH-stimulating Oct-2 gene, and
FF recombination-activating genes RAG-1 and -2 thus stimulating IgH
FF rearrangement as well [12];
FF in acute lymphoblastic leukemias, a t(1,19)(q23,p13.3) translocation fuses
FF the trans-activation domain encoded by the E2A gene with the homeobox of
FF PBX1 [17] [19] [11];
FF the resulting chimeric protein causes acute myeloid leukemia [5] and
FF induces enhanced proliferation as well as apoptosis [6];
XX
IN T00003; AS-C T3; fruit fly, Drosophila melanogaster.
IN T01629; Atoh2; mouse, Mus musculus.
IN T01634; BETA2; hamster.
IN T00204; E12; human, Homo sapiens.
IN T00675; E12; rat, Rattus norvegicus.
IN T01787; E12; clawed frog, Xenopus laevis.
IN T00207; E47; human, Homo sapiens.
IN T01569; Hand1; mouse, Mus musculus.
IN T01447; HEN1; rat, Rattus norvegicus.
IN T01652; HES-5; rat, Rattus norvegicus.
IN T00403; Id1; mouse, Mus musculus.
IN T00404; Id2; mouse, Mus musculus.
IN T01212; Id2; human, Homo sapiens.
IN T01658; Id4; mouse, Mus musculus.
IN T00506; MEF1; mouse, Mus musculus.
IN T00512; MRF4; rat, Rattus norvegicus.
IN T00520; Myf-4; human, Homo sapiens.
IN T00521; Myf-5; human, Homo sapiens.
IN T00949; Myf-5; clawed frog, Xenopus laevis.
IN T00522; Myf-6; human, Homo sapiens.
IN T00524; MyoD; clawed frog, Xenopus laevis.
IN T00525; MyoD; human, Homo sapiens.
IN T00526; MyoD; mouse, Mus musculus.
IN T00527; MyoD; monkey, Cercopithecus aethiops.
IN T01128; MyoD; chick, Gallus gallus.
IN T00528; myogenin; mouse, Mus musculus.
IN T00790; Tal-1; human, Homo sapiens.
IN T01448; Tal-1beta; human, Homo sapiens.
IN T01630; Tal-2; human, Homo sapiens.
IN T01631; Tal-2; mouse, Mus musculus.
XX
XX
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RN [1]; RE0005830.
RX MEDLINE; 95166225.
RA Robinson G. L. W. G., Henderson E., Massari M. E., Murre C., Stein R.
RT c-Jun inhibits insulin control element-mediated transcription by affecting
RT the transactivation potential of the E2A gene products
RL Mol. Cell. Biol. 15:1398-1404 (1995).
RN [2]; RE0004023.
RX MEDLINE; 94119077.
RA Hsu H.-L., Huang L., Tsan J. T., Funk W., Wright W. E., Hu J.-S., Klingston
RA R. E., Baer R.
RT Preferred sequence for DNA recognition by the TAL1 helix-loop-helix proteins
RL Mol. Cell. Biol. 14:1256-1265 (1994).
RN [3]; RE0004025.
RX MEDLINE; 95011595.
RA Ellenberger T., Fass D., Arnaud M., Harrison S. C.
RT Crystal structure of transcription factor E47: E-box recognition by a basic
RT region helix-loop-helix dimer
RL Genes Dev. 8:970-980 (1994).
RN [4]; RE0003543.
RX MEDLINE; 93140777.
RA Quong M. W., Massari M. E., Zwart R., Murre C.
RT A new transcriptional-activation motif restricted to a class of
RT helix-loop-helix proteins is functionally conserved in both yeast and
RT mammalian cells
RL Mol. Cell. Biol. 13:792-800 (1993).
RN [5]; RE0004018.
RX MEDLINE; 93109319.
RA Kamps M. P., Baltimore D.
RT E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute
RT lymphocytic leukemia causes acute myeloid leukemia in mice
RL Mol. Cell. Biol. 13:351-357 (1993).
RN [6]; RE0005180.
RX MEDLINE; 93386756.
RA Dedera D. A., Waller E. K., LeBrun D. P., Sen-Majumdar A., Stevens M. E.,
RA Barsh G. S., Cleary M. L.
RT Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and
RT malignant lymphomas in transgenic mice
RL Cell 74:833-843 (1993).
RN [7]; RE0003408.
RX MEDLINE; 92388090.
RA Chakraborty T., Martin J. F., Olson E. N.
RT Analysis of the oligomerization of myogenin and E2A products in vivo using
RT a two-hybrid assay system
RL J. Biol. Chem. 267:17498-17501 (1992).
RN [8]; RE0000231.
RX MEDLINE; 91105861.
RA Sun X.-H., Baltimore D.
RT An inhibitory domain of E12 transcription factor prevents DNA binding in
RT E12 homodimers but not in E12 heterodimers
RL Cell 64:459-470 (1991).
RN [9]; RE0000238.
RX MEDLINE; 91309143.
RA Lassar A. B., Davis R. L., Wright W. E., Kadesch T., Murre C., Voronova A.,
RA Baltimore D., Weintraub H.
RT Functional activity of myogenic HLH proteins requires
RT hetero-oligomerization with E12/E47-like proteins in vivo
RL Cell 66:305-315 (1991).
RN [10]; RE0000670.
RX MEDLINE; 91115096.
RA Ruezinsky D., Beckmann H., Kadesh T.
RT Modulation of the Igh enhancer's cell type through a genetic switch
RL Genes Dev. 5:29-37 (1991).
RN [11]; RE0000671.
RX MEDLINE; 91160969.
RA Kamps M. P., Look A. T., Baltimore D.
RT The human t(1;19) translocation in pre-B ALL produces multiple nuclear
RT E2A-Pbx1 fusion proteins with differing transforming potentials
RL Genes Dev. 5:358-368 (1991).
RN [12]; RE0000672.
RX MEDLINE; 91331308.
RA Schlissel M., Voronova A., Baltimore D.
RT Helix-loop-helix transcription factor E47 activates germ-line
RT immunoglobulin heavy-chain gene transcription and rearrangement in a
RT pre-T-cell line
RL Genes Dev. 5:1367-1376 (1991).
RN [13]; RE0001469.
RX MEDLINE; 91117219.
RA Murre C., Voronova A., Baltimore D.
RT B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like
RT subunits
RL Mol. Cell. Biol. 11:1156-1160 (1991).
RN [14]; RE0001629.
RX MEDLINE; 91246170.
RA Hsu H.-L., Cheng J.-T., Chen Q., Baer R.
RT Enhancer-binding activity of the tal-1 oncoprotein in association with the
RT E47/E12 helix-loop-helix proteins
RL Mol. Cell. Biol. 11:3037-3042 (1991).
RN [15]; RE0004160.
RX MEDLINE; 91141527.
RA Cordle S. R., Henderson E., Masuoka H., Weil P. A., Stein R.
RT Pancreatic beta-cell-type-specific transcription of the insulin gene is
RT mediated by basic helix-loop-helix DNA-binding proteins
RL Mol. Cell. Biol. 11:1734-1738 (1991).
RN [16]; RE0000055.
RX MEDLINE; 90199896.
RA Benezra R., Davis R. L., Lockshon D., Turner D. L., Weintraub H.
RT The protein Id: a negative regulator of helix-loop-helix DNA binding
RT proteins
RL Cell 61:49-59 (1990).
RN [17]; RE0000161.
RX MEDLINE; 90150281.
RA Nourse J., Mellentin J. D., Galili N., Wilkinson J., Stanbridge E., Smith
RA S. D., Cleary M. L.
RT Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion
RT mRNA that codes for a potential chimeric transcription factor
RL Cell 60:535-545 (1990).
RN [18]; RE0002524.
RX MEDLINE; 90280447.
RA Voronova A., Baltimore D.
RT Mutations that disrupt DNA binding and dimer formation in the E47
RT helix-loop-helix protein map to distinct domains
RL Proc. Natl. Acad. Sci. USA 87:4722-4726 (1990).
RN [19]; RE0004014.
RX MEDLINE; 90150282.
RA Kamps M. P., Murre C., Sun X. H., Baltimore D.
RT A new homeobox gene contributes the DNA binding domain oft the t(1; 19)
RT translocation protein in pre-B ALL
RL Cell 60:547-555 (1990).
RN [20]; RE0000053.
RX MEDLINE; 89336785.
RA Murre C., McCaw P. S., Vaessin H., Caudy M., Jan L. Y., Jan Y. N., Cabrera
RA C. V., Buskin J. N., Hauschka S. D., Lassar A. B., Weintraub H., Baltimore
RA D.
RT Interactions between heterologous helix-loop-helix proteins generate
RT complexes that bind specifically to a common DNA sequence
RL Cell 58:537-544 (1989).
RN [21]; RE0000092.
RX MEDLINE; 89168418.
RA Murre C., McCaw P. S., Baltimore D.
RT A new DNA binding and dimerization motif in immunoglobulin enhancer
RT binding, daughterless, MyoD, and myc proteins
RL Cell 56:777-783 (1989).
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Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

256 genes, 256 accessions (Toggle view)

AccessionGeneTitleLinks
PELOPELOpelota homolog (Drosophila)Source|GeneCards
FLJ90637C1ORF118chromosome 1 open reading frame 118Source|GeneCards
CORO1ACORO1Acoronin, actin binding protein, 1ASource|GeneCards
MGAT1MGAT1mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferaseSource|GeneCards
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)Source|GeneCards
KHDRBS2KHDRBS2KH domain containing, RNA binding, signal transduction associated 2Source|GeneCards
PAK3PAK3p21 (CDKN1A)-activated kinase 3Source|GeneCards
C20ORF178C20ORF178chromosome 20 open reading frame 178Source|GeneCards
TSHRTSHRthyroid stimulating hormone receptorSource|GeneCards
MGC14161FRMD5FERM domain containing 5Source|GeneCards
ZNF532ZNF532zinc finger protein 532Source|GeneCards
PLK4PLK4polo-like kinase 4 (Drosophila)Source|GeneCards
ITGA6ITGA6integrin, alpha 6Source|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)Source|GeneCards
KCNB1KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1Source|GeneCards
NLKNLKnemo like kinaseSource|GeneCards
DKFZP564F0522DKFZP564F0522DKFZP564F0522 proteinSource|GeneCards
SORCS2SORCS2VPS10 domain receptor proteinSource|GeneCards
MLL5MLL5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)Source|GeneCards
SOX12SOX12SRY (sex determining region Y)-box 12Source|GeneCards
ERFERFEts2 repressor factorSource|GeneCards
OTOSOTOSotospiralinSource|GeneCards
SPI1SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi1Source|GeneCards
CORO1CCORO1Ccoronin, actin binding protein, 1CSource|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
WTAPWTAPWilms tumor 1 associated proteinSource|GeneCards
FLJ13848FLJ13848hypothetical protein FLJ13848Source|GeneCards
PLCB3PLCB3phospholipase C, beta 3 (phosphatidylinositol-specific)Source|GeneCards
CACNB3CACNB3calcium channel, voltage-dependent, beta 3 subunitSource|GeneCards
DERP6DERP6S-phase 2 proteinSource|GeneCards
FLNCFLNCfilamin C, gamma (actin binding protein 280)Source|GeneCards
IRF1IRF1interferon regulatory factor 1Source|GeneCards
DELGEFDELGEFdeafness locus associated putative guanine nucleotide exchange factorSource|GeneCards
ANKRD2ANKRD2ankyrin repeat domain 2 (stretch responsive muscle)Source|GeneCards
MAP3K3MAP3K3mitogen-activated protein kinase kinase kinase 3Source|GeneCards
CCND2CCND2cyclin D2Source|GeneCards
SH3GLB2SH3GLB2SH3-domain GRB2-like endophilin B2Source|GeneCards
ABLIM3ABLIM3actin binding LIM protein family, member 3Source|GeneCards
FLJ38792FLJ38792hypothetical protein FLJ38792Source|GeneCards
EIF4ENIF1EIF4ENIF1eukaryotic translation initiation factor 4E nuclear import factor 1Source|GeneCards
SCN5ASCN5Asodium channel, voltage-gated, type V, alpha (long QT syndrome 3)Source|GeneCards
ELAVL3ELAVL3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)Source|GeneCards
LOC147650LOC147650hypothetical protein LOC147650Source|GeneCards
C5ORF16C5ORF16chromosome 5 open reading frame 16Source|GeneCards
UBE2D3UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)Source|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
PCDH17PCDH17protocadherin 17Source|GeneCards
CD47CD47CD47 antigen (Rh-related antigen, integrin-associated signal transducer)Source|GeneCards
CALB1CALB1calbindin 1, 28kDaSource|GeneCards
DUSP10DUSP10dual specificity phosphatase 10Source|GeneCards
KCNK12KCNK12potassium channel, subfamily K, member 12Source|GeneCards
TNRC4TNRC4trinucleotide repeat containing 4Source|GeneCards
HSD3B7HSD3B7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7Source|GeneCards
NODALNODALnodal homolog (mouse)Source|GeneCards
VPS13AVPS13Avacuolar protein sorting 13A (yeast)Source|GeneCards
WFIKKNRPWFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2Source|GeneCards
GNB3GNB3guanine nucleotide binding protein (G protein), beta polypeptide 3Source|GeneCards
NSD1NSD1nuclear receptor binding SET domain protein 1Source|GeneCards
KIRREL2KIRREL2kin of IRRE like 2 (Drosophila)Source|GeneCards
IRX5IRX5iroquois homeobox protein 5Source|GeneCards
MGC5309MGC5309hypothetical protein MGC5309Source|GeneCards
NBL1NBL1neuroblastoma, suppression of tumorigenicity 1Source|GeneCards
ARL4AARL4ADP-ribosylation factor-like 4Source|GeneCards
POU2F3POU2F3POU domain, class 2, transcription factor 3Source|GeneCards
CER1CER1cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)Source|GeneCards
PAI-RBP1SERBP1SERPINE1 mRNA binding protein 1Source|GeneCards
DRCTNNB1ADRCTNNB1Adown-regulated by Ctnnb1, aSource|GeneCards
NETO2NETO2neuropilin (NRP) and tolloid (TLL)-like 2Source|GeneCards
CHRDL1CHRDL1chordin-like 1Source|GeneCards
IL23AIL23Ainterleukin 23, alpha subunit p19Source|GeneCards
C6ORF142C6ORF142chromosome 6 open reading frame 142Source|GeneCards
DSCAMDSCAMDown syndrome cell adhesion moleculeSource|GeneCards
EPHB2EPHB2EphB2Source|GeneCards
MTSS1MTSS1metastasis suppressor 1Source|GeneCards
TRIM8TRIM8tripartite motif-containing 8Source|GeneCards
SPTAN1SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)Source|GeneCards
DUSP9DUSP9dual specificity phosphatase 9Source|GeneCards
SORBS1SORBS1sorbin and SH3 domain containing 1Source|GeneCards
DLL4DLL4delta-like 4 (Drosophila)Source|GeneCards
ITGA3ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)Source|GeneCards
TGFB3TGFB3transforming growth factor, beta 3Source|GeneCards
GABRG2GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 2Source|GeneCards
LOC51123LOC51123HSPC038 proteinSource|GeneCards
HRH3HRH3histamine receptor H3Source|GeneCards
TAZTAZtafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)Source|GeneCards
CA7CA7carbonic anhydrase VIISource|GeneCards
BCL9LBCL9LB-cell CLL/lymphoma 9-likeSource|GeneCards
AKAP12AKAP12A kinase (PRKA) anchor protein (gravin) 12Source|GeneCards
ITGA1ITGA1integrin, alpha 1Source|GeneCards
GRCAGPR162G protein-coupled receptor 162Source|GeneCards
STK29STK29serine/threonine kinase 29Source|GeneCards
RORCRORCRAR-related orphan receptor CSource|GeneCards
GJB1GJB1gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)Source|GeneCards
CDYL2CDYL2chromodomain protein, Y-like 2Source|GeneCards
DEF6DEF6differentially expressed in FDCP 6 homolog (mouse)Source|GeneCards
GGNGGNgametogenetinSource|GeneCards
ERN1ERN1ER to nucleus signalling 1Source|GeneCards
MGC50844TSPAN33tetraspanin 33Source|GeneCards
TA-PP2CTA-PP2CT-cell activation protein phosphatase 2CSource|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
HDAC3HDAC3histone deacetylase 3Source|GeneCards
KCNJ4KCNJ4potassium inwardly-rectifying channel, subfamily J, member 4Source|GeneCards
RANGAP1RANGAP1Ran GTPase activating protein 1Source|GeneCards
SLC26A9SLC26A9solute carrier family 26, member 9Source|GeneCards
ARHGAP8ARHGAP8Rho GTPase activating protein 8Source|GeneCards
DRP2DRP2dystrophin related protein 2Source|GeneCards
TRIP10TRIP10thyroid hormone receptor interactor 10Source|GeneCards
CFL1CFL1cofilin 1 (non-muscle)Source|GeneCards
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)Source|GeneCards
FLJ14166FLJ14166hypothetical protein FLJ14166Source|GeneCards
KCNH2KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2Source|GeneCards
PPP2R2BPPP2R2Bprotein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoformSource|GeneCards
KCNQ1DNKCNQ1DNKCNQ1 downstream neighborSource|GeneCards
PLEC1PLEC1plectin 1, intermediate filament binding protein 500kDaSource|GeneCards
SH3BP1SH3BP1SH3-domain binding protein 1Source|GeneCards
AF1QMLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11Source|GeneCards
WNT6WNT6wingless-type MMTV integration site family, member 6Source|GeneCards
FLT3FLT3fms-related tyrosine kinase 3Source|GeneCards
CDK5CDK5cyclin-dependent kinase 5Source|GeneCards
C11ORF30C11ORF30chromosome 11 open reading frame 30Source|GeneCards
WNT10AWNT10Awingless-type MMTV integration site family, member 10ASource|GeneCards
SCAM-1SORBS3sorbin and SH3 domain containing 3Source|GeneCards
NEURLNEURLneuralized-like (Drosophila)Source|GeneCards
SOSTSOSTsclerosteosisSource|GeneCards
BTBD11BTBD11BTB (POZ) domain containing 11Source|GeneCards
CACNA2D2CACNA2D2calcium channel, voltage-dependent, alpha 2/delta subunit 2Source|GeneCards
CHRDCHRDchordinSource|GeneCards
ASB2ASB2ankyrin repeat and SOCS box-containing 2Source|GeneCards
KBTBD5KBTBD5kelch repeat and BTB (POZ) domain containing 5Source|GeneCards
RBPSUHRBPSUHrecombining binding protein suppressor of hairless (Drosophila)Source|GeneCards
AMD1AMD1adenosylmethionine decarboxylase 1Source|GeneCards
NUMBLNUMBLnumb homolog (Drosophila)-likeSource|GeneCards
EIF2C1EIF2C1eukaryotic translation initiation factor 2C, 1Source|GeneCards
ARV1ARV1likely ortholog of yeast ARV1Source|GeneCards
KIAA1221ZNF644Zinc finger protein 644Source|GeneCards
PRM2PRM2protamine 2Source|GeneCards
MYLIPMYLIPmyosin regulatory light chain interacting proteinSource|GeneCards
H63CASC4cancer susceptibility candidate 4Source|GeneCards
C11ORF8C11ORF8chromosome 11 open reading frame 8Source|GeneCards
DAAM1DAAM1dishevelled associated activator of morphogenesis 1Source|GeneCards
MAZMAZMYC-associated zinc finger protein (purine-binding transcription factor)Source|GeneCards
TTC17TTC17Tetratricopeptide repeat domain 17Source|GeneCards
LOC389792
RXRGRXRGretinoid X receptor, gammaSource|GeneCards
SEC31L2SEC31L2SEC31-like 2 (S. cerevisiae)Source|GeneCards
GPM6BGPM6Bglycoprotein M6BSource|GeneCards
C5ORF6FAM53Cfamily with sequence similarity 53, member CSource|GeneCards
GCNT3GCNT3glucosaminyl (N-acetyl) transferase 3, mucin typeSource|GeneCards
GRB2GRB2growth factor receptor-bound protein 2Source|GeneCards
CORO2ACORO2Acoronin, actin binding protein, 2ASource|GeneCards
TIEGKLF10Kruppel-like factor 10Source|GeneCards
LOC56901LOC56901NADH:ubiquinone oxidoreductase MLRQ subunit homologSource|GeneCards
CKMCKMcreatine kinase, muscleSource|GeneCards
ID1ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinSource|GeneCards
AIG1AIG1androgen-induced 1Source|GeneCards
EPB41EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)Source|GeneCards
C1ORF14C1ORF14chromosome 1 open reading frame 14Source|GeneCards
HMP19HMP19HMP19 proteinSource|GeneCards
SEC15L1SEC15L1SEC15-like 1 (S. cerevisiae)Source|GeneCards
PSIP1PSIP1PC4 and SFRS1 interacting protein 1Source|GeneCards
SEMA4BSEMA4Bsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4BSource|GeneCards
C1QGC1QGcomplement component 1, q subcomponent, gamma polypeptideSource|GeneCards
RAB26RAB26RAB26, member RAS oncogene familySource|GeneCards
CYP26A1CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 1Source|GeneCards
FLJ30058FLJ30058hypothetical protein FLJ30058Source|GeneCards
CHD5CHD5chromodomain helicase DNA binding protein 5Source|GeneCards
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)Source|GeneCards
STC2STC2stanniocalcin 2Source|GeneCards
INHAINHAinhibin, alphaSource|GeneCards
CCL27CCL27chemokine (C-C motif) ligand 27Source|GeneCards
GPR37GPR37G protein-coupled receptor 37 (endothelin receptor type B-like)Source|GeneCards
TREML2TREML2Triggering receptor expressed on myeloid cells-like 2Source|GeneCards
LGALS1LGALS1lectin, galactoside-binding, soluble, 1 (galectin 1)Source|GeneCards
HES6HES6hairy and enhancer of split 6 (Drosophila)Source|GeneCards
MAP1AMAP1Amicrotubule-associated protein 1ASource|GeneCards
MUSKMUSKmuscle, skeletal, receptor tyrosine kinaseSource|GeneCards
GKGKGlycerol kinaseSource|GeneCards
FLJ40432FLJ40432hypothetical protein FLJ40432Source|GeneCards
CNNM2CNNM2cyclin M2Source|GeneCards
KLHL13KLHL13kelch-like 13 (Drosophila)Source|GeneCards
CAMK1DCAMK1Dcalcium/calmodulin-dependent protein kinase IDSource|GeneCards
KCNIP2KCNIP2Kv channel interacting protein 2Source|GeneCards
CYLDCYLDcylindromatosis (turban tumor syndrome)Source|GeneCards
SDPRSDPRserum deprivation response (phosphatidylserine binding protein)Source|GeneCards
SPEC1CDC42SE1CDC42 small effector 1Source|GeneCards
FLJ44881FLJ44881FLJ44881 proteinSource|GeneCards
RBL1RBL1retinoblastoma-like 1 (p107)Source|GeneCards
DGKDDGKDdiacylglycerol kinase, delta 130kDaSource|GeneCards
IDEIDEinsulin-degrading enzymeSource|GeneCards
PTK2BPTK2BPTK2B protein tyrosine kinase 2 betaSource|GeneCards
C9ORF150C9ORF150chromosome 9 open reading frame 150Source|GeneCards
TRPV3TRPV3transient receptor potential cation channel, subfamily V, member 3Source|GeneCards
MGC8685MGC8685tubulin, beta polypeptide paralogSource|GeneCards
OTX1OTX1orthodenticle homolog 1 (Drosophila)Source|GeneCards
ONECUT1ONECUT1one cut domain, family member 1Source|GeneCards
MACF1MACF1microtubule-actin crosslinking factor 1Source|GeneCards
GIT2GIT2G protein-coupled receptor kinase-interactor 2Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
C9ORF126C9ORF126chromosome 9 open reading frame 126Source|GeneCards
DNAJB5DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5Source|GeneCards
WNT9AWNT9Awingless-type MMTV integration site family, member 9ASource|GeneCards
EFNA1EFNA1ephrin-A1Source|GeneCards
VKORC1L1VKORC1L1vitamin K epoxide reductase complex, subunit 1-like 1Source|GeneCards
KIAA0182KIAA0182KIAA0182 proteinSource|GeneCards
PPP1R9BPPP1R9Bprotein phosphatase 1, regulatory subunit 9B, spinophilinSource|GeneCards
ISL1ISL1ISL1 transcription factor, LIM/homeodomain, (islet-1)Source|GeneCards
EPHA2EPHA2EphA2Source|GeneCards
MGC11271MGC11271hypothetical protein MGC11271Source|GeneCards
DDIT4LDDIT4LDNA-damage-inducible transcript 4-likeSource|GeneCards
SCRT2SCRT2scratch homolog 2, zinc finger protein (Drosophila)Source|GeneCards
DTX2DTX2deltex homolog 2 (Drosophila)Source|GeneCards
VEGFVEGFvascular endothelial growth factorSource|GeneCards
WNT2BWNT2Bwingless-type MMTV integration site family, member 2BSource|GeneCards
RYR1RYR1ryanodine receptor 1 (skeletal)Source|GeneCards
TTC13TTC13tetratricopeptide repeat domain 13Source|GeneCards
SPOPSPOPspeckle-type POZ proteinSource|GeneCards
CACNA1HCACNA1Hcalcium channel, voltage-dependent, alpha 1H subunitSource|GeneCards
PEX10PEX10peroxisome biogenesis factor 10Source|GeneCards
EMILIN3EMILIN3Elastin microfibril interfacer 3Source|GeneCards
FLJ21019FLJ21019hypothetical protein FLJ21019Source|GeneCards
ARRB2ARRB2arrestin, beta 2Source|GeneCards
KIAA0089GPD1Lglycerol-3-phosphate dehydrogenase 1-likeSource|GeneCards
CITED2CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2Source|GeneCards
FGF9FGF9fibroblast growth factor 9 (glia-activating factor)Source|GeneCards
MTVR1MTVR1Mouse Mammary Turmor Virus Receptor homolog 1Source|GeneCards
MYO7AMYO7Amyosin VIIA (Usher syndrome 1B (autosomal recessive, severe))Source|GeneCards
RUNX1RUNX1runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)Source|GeneCards
THRATHRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
RNF13RNF13ring finger protein 13Source|GeneCards
C7ORF16C7ORF16chromosome 7 open reading frame 16Source|GeneCards
PDGFBPDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)Source|GeneCards
KIAA1318RGAG1retrotransposon gag domain containing 1Source|GeneCards
EPB41L4BEPB41L4Berythrocyte membrane protein band 4.1 like 4BSource|GeneCards
PRKCABPPRKCABPprotein kinase C, alpha binding proteinSource|GeneCards
DPYSL5DPYSL5dihydropyrimidinase-like 5Source|GeneCards
GNA11GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)Source|GeneCards
CAMK2GCAMK2Gcalcium/calmodulin-dependent protein kinase (CaM kinase) II gammaSource|GeneCards
LOC129285LOC129285smooth muscle myosin heavy chain 11 isoform SM1-likeSource|GeneCards
CAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase (CaM kinase) II alphaSource|GeneCards
SLC39A5SLC39A5solute carrier family 39 (metal ion transporter), member 5Source|GeneCards
DULLARDDULLARDdullard homolog (Xenopus laevis)Source|GeneCards
HOXA7HOXA7homeo box A7Source|GeneCards
WIG1WIG1p53 target zinc finger proteinSource|GeneCards
RAB5BRAB5BRAB5B, member RAS oncogene familySource|GeneCards
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3Source|GeneCards
PODXLPODXLpodocalyxin-likeSource|GeneCards
CBFA2T3CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 3Source|GeneCards
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1Source|GeneCards
GNASGNASGNAS complex locusSource|GeneCards
SLC4A2SLC4A2solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)Source|GeneCards
EPHB6EPHB6EphB6Source|GeneCards
FLJ21308PARP8Poly (ADP-ribose) polymerase family, member 8Source|GeneCards
NCOA5NCOA5nuclear receptor coactivator 5Source|GeneCards
MINKKCNE1potassium voltage-gated channel, Isk-related family, member 1Source|GeneCards


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