[an error occurred while processing this directive]
Gene set: V$MYCMAX_01 (C3:TFAC:0070)
Standard nameV$MYCMAX_01
Systematic nameC3:TFAC:0070
Brief descriptionGenes with 3'UTR containing motif NNACCACGTGGTNN which matches annotation for MYC: V-myc myelocytomatosis viral oncogene homolog (avian)
MAX: MAX protein
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

Toggle abstract view

XX
 XX
 XX
 FA Max1
 XX
 SY Max; Myn (mouse); p21.

XX
 OS human, Homo sapiens
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0012; bHLH-ZIP; 1.3.2.2.1.2.
 XX
 SZ 151
AA; 17.2 kDa (cDNA), 21kDa (SDS) [17]
 XX
 XX
 SC edited
SwissProt #P25912
 XX
 FT 2 2 Ser-phosphorylation by CKII
[8].
 FT 3 14 acidic region (7/12).
 FT 11 11 Ser-phosphorylation
by CKII [8].
 FT 15 26 basic region.
 FT 15 66 PF00010;
HLH.
 FT 20 71 SM00353; HLH.
 FT 27 66 helix-loop-helix
domain.
 FT 65 93 leucine zipper (MHL3).
 FT 90 151 replaced
in delta Max by GESES [16].
 FT 140 147 nuclear localization
signal (NLS) [13].
 XX
 SF several splice variants ,
 detected;
 SF Max homodimers and Myc/Max heterodimers
exhibit different preferences for
 SF the trinucleotides flanking
the core sequence (CACGTG) [5];
 SF Max1 and Max2 also differ
slightly in their DNA-binding specificity [5]
 SF [12];

SF heterodimers with either c-Myc or Mad exert higher DNA-binding
affinity
 SF than Max homodimers unless the inhibiting CKII
phosphorylation site is
 SF replaced by alanine [9] [14] [4];

SF heterodimerization requires the leucine zipper, but not homodimerization

SF [13] [20];
 SF DNA-binding by Max or Myc/Max induces bending
towards the minor groove by
 SF 74-82 deg, but possibly in
opposite orientiations [15] [19];
 SF belongs to group B HLH-proteins
that bind to CACGTG motif in DNA [2] which
 SF is due to certain
residues in DNA-binding domain (His at pos. 19, Glu at
 SF
pos. 23, Arg at pos. 27) [2] [1];
 XX
 FF enhances c-Myc
DNA-binding;
 FF in high concentrations: homodimers suppress
c-Myc activities by competition
 FF [13] [16] [6];
 FF after
CKII phosphorylation, increases in on- and off-rates of DNA-binding

FF of homo- and heterodimers have been found [8];
 FF preferentially
complexed with Mad instead of c-Myc upon myeloid
 FF differentiation
[11];
 XX
 IN T00140; c-Myc; human, Homo sapiens.
 IN
T00141; c-Myc; chick, Gallus gallus.
 IN T00142; c-Myc; rat,
Rattus norvegicus.
 IN T00143; c-Myc; mouse, Mus musculus.

IN T01566; deltaMax; human, Homo sapiens.
 IN T02385; L-Myc-1(long
form); human, Homo sapiens.
 IN T02388; L-Myc-1; clawed frog,
Xenopus laevis.
 IN T02389; L-Myc-2; clawed frog, Xenopus laevis.

IN T02387; L-Myc1; mouse, Mus musculus.
 IN T01565; Mad1; human,
Homo sapiens.
 IN T02390; Mad1; mouse, Mus musculus.
 IN
T02391; Mad3; mouse, Mus musculus.
 IN T02392; Mad4; mouse,
Mus musculus.
 IN T00489; Max1; human, Homo sapiens.
 IN
T01564; Mxi1; human, Homo sapiens.
 IN T01445; N-Myc; mouse,
Mus musculus.
 IN T02379; N-Myc; human, Homo sapiens.
 IN
T03268; Rox; human, Homo sapiens.
 XX
 XX
 XX
 XX

RN [1]; RE0017817.
 RX MEDLINE; 20528627.
 RA Billin A.
N., Eilers A. L., Coulter K. L., Logan J. S., Ayer D. E.
 RT
MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional

RT activator that constitutes a positive branch of a max-like
network
 RL Mol. Cell. Biol. 20:8845-8854 (2000).
 RN [2];
RE0017805.
 RX MEDLINE; 99075645.
 RA Meng X., Lu X., Li
Z., Green E. D., Massa H., Trask B. J., Morris C. A.,
 RA Keating
M. T.
 RT Complete physical map of the common deletion region
in Williams syndrome
 RT and identification and characterization
of three novel genes
 RL Hum. Genet. 103:590-599 (1998).

RN [3]; RE0014442.
 RX MEDLINE; 97327566.
 RA Meroni G.,
Reymond A., Alcalay M., Borsani G., Tanigami A., Tonlorenzi R.,

RA Nigro C. L., Messali S., Zollo M., Ledbetter D. H., Brent R.,
Ballabio A.,
 RA Carrozzo R.
 RT Rox, a novel bHLHZip protein
expressed in quiescent cells that
 RT heterodimerizes with
Max, binds a non-canonical E box and acts as a
 RT transcriptional
repressor
 RL EMBO J. 16:2892-2906 (1997).
 RN [4]; RE0005829.

RX MEDLINE; 96081945.
 RA Kohlhuber F., Hermeking H., Graessmann
A., Eick D.
 RT Induction of apoptosis by the c-Myc helix-loop-helix/leucine
zipper domain
 RT in mouse 3T3-L1 fibroblasts
 RL J. Biol.
Chem. 270:28797-28805 (1995).
 RN [5]; RE0002937.
 RX MEDLINE;
94089386.
 RA Solomon D. L. C., Amati B., Land H.
 RT Distinct
DNA binding preferences for the c-Myc/Max and Max/Max dimers

RL Nucleic Acids Res. 21:5372-5376 (1993).
 RN [6]; RE0003361.

RX MEDLINE; 93145325.
 RA Amati B., Brooks M. W., Levy N.,
Littlewood T. D., Evan G. I., Land H.
 RT Oncogenic activity
of the c-Myc protein requires dimerization with Max
 RL Cell
72:233-245 (1993).
 RN [7]; RE0003399.
 RX MEDLINE; 94085381.

RA Fisher F., Crouch D. H., Jayaraman P. S., Clark W., Gillespie
D. A. F.,
 RA Goding C. R.
 RT Transcription activation
by Myc and Max: flanking sequences target
 RT activation to
a subset of CACGTG motifs in vivo
 RL EMBO J. 12:5075-5082
(1993).
 RN [8]; RE0003400.
 RX MEDLINE; 94067769.
 RA
Bousset K., Henriksson M., Luescher-Firzlaff J. M., Litchfield
D. W.,
 RA Luescher B.
 RT Identification of casein kinase
II phosphorylation sites in Max: effects on
 RT DNA-binding
kinetics of Max homo- and Myc/Max heterodimers
 RL Oncogene
8:3211-3220 (1993).
 RN [9]; RE0003401.
 RX MEDLINE; 93145323.

RA Ayer D. E., Kretzner L., Eisenman R. N.
 RT Mad: a heterodimeric
partner for Max that antagonizes Myc transcriptional
 RT activity

RL Cell 72:211-222 (1993).
 RN [10]; RE0003402.
 RX MEDLINE;
93145324.
 RA Zervos A. S., Gyuris J., Brent R.
 RT Mxi1,
a protein that specifically interacts with Max to bind Myc-Max

RT recognition sites
 RL Cell 72:223-232 (1993).
 RN [11];
RE0003403.
 RX MEDLINE; 94040733.
 RA Ayer D. E., Eisenman
R. N.
 RT A switch from Myc:Max to Mad:Max heterocomplexes
accompanies
 RT monocyte/macrophage differentiation
 RL
Genes Dev. 7:2110-2119 (1993).
 RN [12]; RE0003404.
 RX
MEDLINE; 93157390.
 RA Prochownik E. V., Antwerp M. E.

RT Differential patterns of DNA binding by myc and max proteins

RL Proc. Natl. Acad. Sci. USA 90:960-964 (1993).
 RN [13];
RE0000704.
 RX MEDLINE; 92112038.
 RA Kato G. J., Lee W.
M. F., Chen L., Dang C. V.
 RT Max: functional domains and
interaction with c-Myc
 RL Genes Dev. 6:81-92 (1992).
 RN
[14]; RE0000705.
 RX MEDLINE; 92146952.
 RA Berberich S.
J., Cole M. D.
 RT Casein kinase II inhibits the DNA-binding
activity of Max homodimers but
 RT not Myc/Max heterodimers

RL Genes Dev. 6:166-176 (1992).
 RN [15]; RE0003338.
 RX
MEDLINE; 93101610.
 RA Fisher D. E., Parent L. A., Sharp P.
A.
 RT Myc/Max and other helix-loop-helix/leucine zipper proteins
bend DNA toward
 RT the minor groove
 RL Proc. Natl. Acad.
Sci. USA 89:11779-11783 (1992).
 RN [16]; RE0003350.
 RX
MEDLINE; 92229468.
 RA Maekelae T. P., Koskinen P. J., Vaestrik
I., Alitalo K.
 RT Alternative forms of Max as enhancers or
suppressors of Myc-Ras
 RT cotransformation
 RL Science
256:373-377 (1992).
 RN [17]; RE0003353.
 RX MEDLINE; 92112037.

RA Blackwood E. M., Luescher B., Eisenman R. N.
 RT Myc and
Max associate in vivo
 RL Genes Dev. 6:71-80 (1992).
 RN
[18]; RE0003387.
 RX MEDLINE; 92334862.
 RA Min S., Taparowsky
E. J.
 RT v-Myc, but not Max, possesses domains that function
in both transcription
 RT activation and cellular transformation

RL Oncogene 7:1531-1540 (1992).
 RN [19]; RE0003396.
 RX
MEDLINE; 92366516.
 RA Wechsler D. S., Dang C. V.
 RT Opposite
directions of DNA bending by c-Myc and Max
 RL Proc. Natl.
Acad. Sci. USA 89:7635-7639 (1992).
 RN [20]; RE0003397.

RX MEDLINE; 93026389.
 RA Reddy C. D., Dasgupta P., Saikumar
P., Dudek H., Rauscher III F. J., Reddy
 RA E. P.
 RT Mutational
analysis of Max: role of basic, helix-loop-helix/leucine zipper

RT domains in DNA binding, dimerization and regulation of Myc-mediated

RT transcriptional activation
 RL Oncogene 7:2085-2092 (1992).

RN [21]; RE0003398.
 RX MEDLINE; 92212978.
 RA Wagner A.
J., Le Beau M. M., Diaz M. O., Hay N.
 RT Expression, regulation,
and chromosomal localization of the Max gene
 RL Proc. Natl.
Acad. Sci. USA 89:3111-3115 (1992).
 RN [22]; RE0000477.

RX MEDLINE; 92037532.
 RA Wenzel A., Cziepluch C., Hamann U.,
Schuermann J., Schwab M.
 RT The N-Myc oncoprotein is associated
in vivo with the phosphoprotein
 RT Max(p20/22) in human neuroblastoma
cells
 RL EMBO J. 10:3703-3712 (1991).
 RN [23]; RE0002653.

RX MEDLINE; 91173288.
 RA Blackwood E. M., Eisenman R. N.

RT Max: a helix-loop-helix zipper protein that forms a sequence-specific

RT DNA-binding complex with Myc
 RL Science 251:1211-1217 (1991).

XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

261 genes, 261 accessions (Toggle view)

AccessionGeneTitleLinks
PITX3PITX3paired-like homeodomain transcription factor 3Source|GeneCards
LOC147727LOC147727hypothetical protein LOC147727Source|GeneCards
ASE-1CD3EAPCD3E antigen, epsilon polypeptide associated proteinSource|GeneCards
RUNX2RUNX2runt-related transcription factor 2Source|GeneCards
DKFZP547B139DKFZP547B139hypothetical protein DKFZp547B139Source|GeneCards
H3F3AH3F3AH3 histone, family 3ASource|GeneCards
KCNN4KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4Source|GeneCards
FOXD3FOXD3forkhead box D3Source|GeneCards
FLJ14451ZC3H10zinc finger CCCH-type containing 10Source|GeneCards
TRIM46TRIM46tripartite motif-containing 46Source|GeneCards
GPC3GPC3glypican 3Source|GeneCards
CADCADcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotaseSource|GeneCards
BCAS3BCAS3breast carcinoma amplified sequence 3Source|GeneCards
CHRM1CHRM1cholinergic receptor, muscarinic 1Source|GeneCards
MYCL1MYCL1v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)Source|GeneCards
MNTMNTMAX binding proteinSource|GeneCards
MGC8407CAMKVCaM kinase-like vesicle-associatedSource|GeneCards
DAZAP1DAZAP1DAZ associated protein 1Source|GeneCards
DD5EDD1E3 ubiquitin protein ligase, HECT domain containing, 1Source|GeneCards
RANBP1RANBP1RAN binding protein 1Source|GeneCards
PDIPPDIPprotein disulfide isomerase, pancreaticSource|GeneCards
TOP1TOP1topoisomerase (DNA) ISource|GeneCards
ZHX2ZHX2transcription factor ZHX2Source|GeneCards
ILF3ILF3interleukin enhancer binding factor 3, 90kDaSource|GeneCards
ARL3ARL3ADP-ribosylation factor-like 3Source|GeneCards
HNRPDLHNRPDLheterogeneous nuclear ribonucleoprotein D-likeSource|GeneCards
TAFA4FAM19A4family with sequence similarity 19 (chemokine (C-C motif)-like), member A4Source|GeneCards
MXD4MXD4MAX dimerization protein 4Source|GeneCards
TESK2TESK2testis-specific kinase 2Source|GeneCards
LIN28LIN28lin-28 homolog (C. elegans)Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
D1S155ECSDE1cold shock domain containing E1, RNA-bindingSource|GeneCards
GCSHGCSHglycine cleavage system protein H (aminomethyl carrier)Source|GeneCards
FKBP11FKBP11FK506 binding protein 11, 19 kDaSource|GeneCards
MRPL40MRPL40mitochondrial ribosomal protein L40Source|GeneCards
SNX5SNX5sorting nexin 5Source|GeneCards
FLJ20032FLJ20032hypothetical protein FLJ20032Source|GeneCards
ELAVL3ELAVL3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)Source|GeneCards
PPRC1PPRC1peroxisome proliferative activated receptor, gamma, coactivator-related 1Source|GeneCards
WIPI49WIPI49WD40 repeat protein Interacting with phosphoInositides of 49kDaSource|GeneCards
MGC35555RSPO2R-spondin 2 homolog (Xenopus laevis)Source|GeneCards
QTRT1QTRT1queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)Source|GeneCards
CBX5CBX5chromobox homolog 5 (HP1 alpha homolog, Drosophila)Source|GeneCards
TIMM10TIMM10translocase of inner mitochondrial membrane 10 homolog (yeast)Source|GeneCards
PRPS1PRPS1phosphoribosyl pyrophosphate synthetase 1Source|GeneCards
HRMT1L2HRMT1L2HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)Source|GeneCards
SC65SC65synaptonemal complex protein SC65Source|GeneCards
RPS19RPS19ribosomal protein S19Source|GeneCards
RBAF600RBAF600retinoblastoma-associated factor 600Source|GeneCards
XTP3TPAXTP3TPAXTP3-transactivated protein ASource|GeneCards
MGC13272MON1AMON1 homolog A (yeast)Source|GeneCards
MIST1BHLHB8basic helix-loop-helix domain containing, class B, 8Source|GeneCards
FKBP10FKBP10FK506 binding protein 10, 65 kDaSource|GeneCards
HIRAHIRAHIR histone cell cycle regulation defective homolog A (S. cerevisiae)Source|GeneCards
PABPC1PABPC1poly(A) binding protein, cytoplasmic 1Source|GeneCards
HMGA1HMGA1high mobility group AT-hook 1Source|GeneCards
CSPG6CSPG6chondroitin sulfate proteoglycan 6 (bamacan)Source|GeneCards
TGFB2TGFB2transforming growth factor, beta 2Source|GeneCards
PAI-RBP1SERBP1SERPINE1 mRNA binding protein 1Source|GeneCards
FLJ32549FLJ32549hypothetical protein FLJ32549Source|GeneCards
CHD4CHD4chromodomain helicase DNA binding protein 4Source|GeneCards
USP34USP34ubiquitin specific protease 34Source|GeneCards
POU3F2POU3F2POU domain, class 3, transcription factor 2Source|GeneCards
NOL5ANOL5Anucleolar protein 5A (56kDa with KKE/D repeat)Source|GeneCards
LRP8LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptorSource|GeneCards
HTF9CHTF9CHpaII tiny fragments locus 9CSource|GeneCards
IPO13IPO13importin 13Source|GeneCards
ETV1ETV1ets variant gene 1Source|GeneCards
MEOX2MEOX2mesenchyme homeo box 2 (growth arrest-specific homeo box)Source|GeneCards
RFX5RFX5regulatory factor X, 5 (influences HLA class II expression)Source|GeneCards
ESRRAESRRAestrogen-related receptor alphaSource|GeneCards
HHIPHHIPhedgehog interacting proteinSource|GeneCards
ZNF509ZNF509zinc finger protein 509Source|GeneCards
BOKBOKBCL2-related ovarian killerSource|GeneCards
UBE2BUBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)Source|GeneCards
TRIB1TRIB1tribbles homolog 1 (Drosophila)Source|GeneCards
PTMAPTMAprothymosin, alpha (gene sequence 28)Source|GeneCards
SDC1SDC1syndecan 1Source|GeneCards
NRASNRASneuroblastoma RAS viral (v-ras) oncogene homologSource|GeneCards
TERE1UBIAD1UbiA prenyltransferase domain containing 1Source|GeneCards
FLJ43965CCDC4coiled-coil domain containing 4Source|GeneCards
IPO7IPO7importin 7Source|GeneCards
SLC43A1SLC43A1solute carrier family 43, member 1Source|GeneCards
ZBTB10ZBTB10Zinc finger and BTB domain containing 10Source|GeneCards
RTN4RL2RTN4RL2reticulon 4 receptor-like 2Source|GeneCards
CDC14ACDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae)Source|GeneCards
PPATPPATphosphoribosyl pyrophosphate amidotransferaseSource|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
DAZLDAZLdeleted in azoospermia-likeSource|GeneCards
APOA5APOA5apolipoprotein A-VSource|GeneCards
FLJ12355FLJ12355hypothetical protein FLJ12355Source|GeneCards
STXBP2STXBP2syntaxin binding protein 2Source|GeneCards
C20ORF112C20ORF112chromosome 20 open reading frame 112Source|GeneCards
PUS1PUS1pseudouridylate synthase 1Source|GeneCards
HNRPA1HNRPA1heterogeneous nuclear ribonucleoprotein A1Source|GeneCards
GPS1GPS1G protein pathway suppressor 1Source|GeneCards
TCERG1TCERG1transcription elongation regulator 1 (CA150)Source|GeneCards
NDUFS1NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)Source|GeneCards
CRMP1CRMP1collapsin response mediator protein 1Source|GeneCards
KCTD15KCTD15potassium channel tetramerisation domain containing 15Source|GeneCards
RORCRORCRAR-related orphan receptor CSource|GeneCards
EIF4EEIF4Eeukaryotic translation initiation factor 4ESource|GeneCards
KIAA0427KIAA0427KIAA0427Source|GeneCards
KIAA0664KIAA0664KIAA0664 proteinSource|GeneCards
ENO3ENO3enolase 3, (beta, muscle)Source|GeneCards
MAP1DMAP1Dmethionine aminopeptidase 1DSource|GeneCards
FOXO3AFOXO3Aforkhead box O3ASource|GeneCards
MIG12MID1IP1MID1 interacting protein 1 (gastrulation specific G12-like (zebrafish))Source|GeneCards
ETV4ETV4ets variant gene 4 (E1A enhancer binding protein, E1AF)Source|GeneCards
SFXN2SFXN2sideroflexin 2Source|GeneCards
C20ORF72C20ORF72chromosome 20 open reading frame 72Source|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
EWSR1EWSR1Ewing sarcoma breakpoint region 1Source|GeneCards
RAB3IL1RAB3IL1RAB3A interacting protein (rabin3)-like 1Source|GeneCards
TIMM9TIMM9translocase of inner mitochondrial membrane 9 homolog (yeast)Source|GeneCards
NEUROD1NEUROD1neurogenic differentiation 1Source|GeneCards
PAICSPAICSphosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetaseSource|GeneCards
GADD45GGADD45Ggrowth arrest and DNA-damage-inducible, gammaSource|GeneCards
BTBD5BTBD5BTB (POZ) domain containing 5Source|GeneCards
PER1PER1period homolog 1 (Drosophila)Source|GeneCards
MGC13053MGC13053hypothetical protein MGC13053Source|GeneCards
NTN2LNTN2Lnetrin 2-like (chicken)Source|GeneCards
EEF1B2EEF1B2eukaryotic translation elongation factor 1 beta 2Source|GeneCards
KRTCAP2KRTCAP2keratinocyte associated protein 2Source|GeneCards
KCMF1KCMF1potassium channel modulatory factor 1Source|GeneCards
NPM1NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)Source|GeneCards
UBE1UBE1ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing)Source|GeneCards
FLT3FLT3fms-related tyrosine kinase 3Source|GeneCards
IMP-1IMP-1IGF-II mRNA-binding protein 1Source|GeneCards
HSPBAP1HSPBAP1HSPB (heat shock 27kDa) associated protein 1Source|GeneCards
POGKPOGKpogo transposable element with KRAB domainSource|GeneCards
HOXB5HOXB5homeo box B5Source|GeneCards
KIAA1407KIAA1407KIAA1407 proteinSource|GeneCards
MGC10772PRR7proline rich 7 (synaptic)Source|GeneCards
RAMP2RAMP2receptor (calcitonin) activity modifying protein 2Source|GeneCards
PA2G4PA2G4proliferation-associated 2G4, 38kDaSource|GeneCards
OPRS1OPRS1opioid receptor, sigma 1Source|GeneCards
MPP3MPP3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)Source|GeneCards
IVNS1ABPIVNS1ABPinfluenza virus NS1A binding proteinSource|GeneCards
JMJD1AJMJD1Ajumonji domain containing 1ASource|GeneCards
C22ORF14DERL3Der1-like domain family, member 3Source|GeneCards
G6PC3G6PC3glucose-6-phosphatase catalytic subunit 3Source|GeneCards
GPM6BGPM6Bglycoprotein M6BSource|GeneCards
FLJ23861FLJ23861hypothetical protein FLJ23861Source|GeneCards
USP15USP15ubiquitin specific protease 15Source|GeneCards
AMPD2AMPD2adenosine monophosphate deaminase 2 (isoform L)Source|GeneCards
COL2A1COL2A1collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)Source|GeneCards
DKFZP564O0463WDSOF1WD repeats and SOF1 domain containingSource|GeneCards
NUDCNUDCnuclear distribution gene C homolog (A. nidulans)Source|GeneCards
ACY1ACY1aminoacylase 1Source|GeneCards
MGEA6CTAGE5CTAGE family, member 5Source|GeneCards
FLJ20071DYMDymeclinSource|GeneCards
PTGES2PTGES2prostaglandin E synthase 2Source|GeneCards
GJA1GJA1gap junction protein, alpha 1, 43kDa (connexin 43)Source|GeneCards
TCOF1TCOF1Treacher Collins-Franceschetti syndrome 1Source|GeneCards
EPB41EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)Source|GeneCards
FLJ10201YEATS2YEATS domain containing 2Source|GeneCards
KCNQ5KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5Source|GeneCards
BMP4BMP4bone morphogenetic protein 4Source|GeneCards
LOC145741
SLC6A15SLC6A15solute carrier family 6 (neurotransmitter transporter), member 15Source|GeneCards
DIAPH1DIAPH1diaphanous homolog 1 (Drosophila)Source|GeneCards
U2AF2U2AF2U2 (RNU2) small nuclear RNA auxiliary factor 2Source|GeneCards
ATOH8ATOH8Atonal homolog 8 (Drosophila)Source|GeneCards
PSME3PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)Source|GeneCards
MASAMASAE-1 enzymeSource|GeneCards
SLC12A5SLC12A5solute carrier family 12, (potassium-chloride transporter) member 5Source|GeneCards
ADAMTS17ADAMTS17a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17Source|GeneCards
SLC1A7SLC1A7solute carrier family 1 (glutamate transporter), member 7Source|GeneCards
SFRS14SFRS14splicing factor, arginine/serine-rich 14Source|GeneCards
ZADH2ZADH2zinc binding alcohol dehydrogenase, domain containing 2Source|GeneCards
TUBA1TUBA1tubulin, alpha 1 (testis specific)Source|GeneCards
QTRTD1QTRTD1queuine tRNA-ribosyltransferase domain containing 1Source|GeneCards
MTHFD1MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetaseSource|GeneCards
LAP3LAP3Leucine aminopeptidase 3Source|GeneCards
KIAA0586KIAA0586KIAA0586Source|GeneCards
CAB45SDF4stromal cell derived factor 4Source|GeneCards
EIF2C2EIF2C2eukaryotic translation initiation factor 2C, 2Source|GeneCards
FGF14FGF14fibroblast growth factor 14Source|GeneCards
ADAMTS19ADAMTS19a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19Source|GeneCards
PCDHA10PCDHA10protocadherin alpha 10Source|GeneCards
IFRD2IFRD2interferon-related developmental regulator 2Source|GeneCards
SATB2SATB2SATB family member 2Source|GeneCards
ARMETARMETarginine-rich, mutated in early stage tumorsSource|GeneCards
TUBA4TUBA4tubulin, alpha 4Source|GeneCards
CGREF1CGREF1cell growth regulator with EF hand domain 1Source|GeneCards
CNNM1CNNM1cyclin M1Source|GeneCards
KIAA0423KIAA0423KIAA0423Source|GeneCards
ODC1ODC1ornithine decarboxylase 1Source|GeneCards
MAT2AMAT2Amethionine adenosyltransferase II, alphaSource|GeneCards
RCL1RCL1RNA terminal phosphate cyclase-like 1Source|GeneCards
OPRD1OPRD1opioid receptor, delta 1Source|GeneCards
TIMM8ATIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast)Source|GeneCards
LYARLYARhypothetical protein FLJ20425Source|GeneCards
LOC51333LOC51333mesenchymal stem cell protein DSC43Source|GeneCards
CSKCSKc-src tyrosine kinaseSource|GeneCards
CA14CA14carbonic anhydrase XIVSource|GeneCards
HSPA9BHSPA9Bheat shock 70kDa protein 9B (mortalin-2)Source|GeneCards
MLLMLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
GIT1GIT1G protein-coupled receptor kinase-interactor 1Source|GeneCards
RHEBL1RHEBL1Ras homolog enriched in brain like 1Source|GeneCards
ERP70PDIA4protein disulfide isomerase family A, member 4Source|GeneCards
DNAJB5DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5Source|GeneCards
SMAD2SMAD2SMAD, mothers against DPP homolog 2 (Drosophila)Source|GeneCards
FLJ37794FLJ37794hypothetical protein FLJ37794Source|GeneCards
ATF7IPATF7IPactivating transcription factor 7 interacting proteinSource|GeneCards
PFN1PFN1profilin 1Source|GeneCards
PRDX4PRDX4peroxiredoxin 4Source|GeneCards
PPP1R9BPPP1R9Bprotein phosphatase 1, regulatory subunit 9B, spinophilinSource|GeneCards
HOXC11HOXC11homeo box C11Source|GeneCards
ODDGJA1gap junction protein, alpha 1, 43kDa (connexin 43)Source|GeneCards
MAP7MAP7microtubule-associated protein 7Source|GeneCards
MGC19595ARMC6armadillo repeat containing 6Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
SRP72SRP72signal recognition particle 72kDaSource|GeneCards
SCRT2SCRT2scratch homolog 2, zinc finger protein (Drosophila)Source|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
RFX4RFX4regulatory factor X, 4 (influences HLA class II expression)Source|GeneCards
NR6A1NR6A1nuclear receptor subfamily 6, group A, member 1Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
DKFZP566E144REXO2REX2, RNA exonuclease 2 homolog (S. cerevisiae)Source|GeneCards
SNCAIPSNCAIPsynuclein, alpha interacting protein (synphilin)Source|GeneCards
ZNF565ZNF565zinc finger protein 565Source|GeneCards
SUCLG2SUCLG2succinate-CoA ligase, GDP-forming, beta subunitSource|GeneCards
TFRCTFRCtransferrin receptor (p90, CD71)Source|GeneCards
BCL7CBCL7CB-cell CLL/lymphoma 7CSource|GeneCards
ATAD3AATAD3AATPase family, AAA domain containing 3ASource|GeneCards
CYP2D6CYP2D6cytochrome P450, family 2, subfamily D, polypeptide 6Source|GeneCards
MGC3040MGC3040hypothetical protein MGC3040Source|GeneCards
CLN3CLN3ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)Source|GeneCards
DIABLODIABLOdiablo homolog (Drosophila)Source|GeneCards
APG5LAPG5LAPG5 autophagy 5-like (S. cerevisiae)Source|GeneCards
ATAD3BATAD3BATPase family, AAA domain containing 3BSource|GeneCards
WDR23WDR23WD repeat domain 23Source|GeneCards
KCNH4KCNH4potassium voltage-gated channel, subfamily H (eag-related), member 4Source|GeneCards
HNRPH3HNRPH3heterogeneous nuclear ribonucleoprotein H3 (2H9)Source|GeneCards
SYT3SYT3synaptotagmin IIISource|GeneCards
ABCA1ABCA1ATP-binding cassette, sub-family A (ABC1), member 1Source|GeneCards
EFNB1EFNB1ephrin-B1Source|GeneCards
C19ORF4C19ORF4chromosome 19 open reading frame 4Source|GeneCards
ISGF3GISGF3Ginterferon-stimulated transcription factor 3, gamma 48kDaSource|GeneCards
FOXJ3FOXJ3forkhead box J3Source|GeneCards
CEBPACEBPACCAAT/enhancer binding protein (C/EBP), alphaSource|GeneCards
IQGAP2IQGAP2IQ motif containing GTPase activating protein 2Source|GeneCards
RAI14RAI14retinoic acid induced 14Source|GeneCards
NRIP3NRIP3nuclear receptor interacting protein 3Source|GeneCards
NCLNCLnucleolinSource|GeneCards
NOP5/NOP58NOP5/NOP58nucleolar protein NOP5/NOP58Source|GeneCards
GPRC5CGPRC5CG protein-coupled receptor, family C, group 5, member CSource|GeneCards
ASXL1ASXL1additional sex combs like 1 (Drosophila)Source|GeneCards
C22ORF3C22ORF3chromosome 22 open reading frame 3Source|GeneCards
STMN1STMN1stathmin 1/oncoprotein 18Source|GeneCards
MFTCSLC25A32solute carrier family 25, member 32Source|GeneCards
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5Source|GeneCards
C20ORF59C20ORF59chromosome 20 open reading frame 59Source|GeneCards
FLJ21918RBM35BRNA binding motif protein 35BSource|GeneCards
PPARGC1BPPARGC1Bperoxisome proliferative activated receptor, gamma, coactivator 1, betaSource|GeneCards
FGF6FGF6fibroblast growth factor 6Source|GeneCards
DIRC2DIRC2disrupted in renal carcinoma 2Source|GeneCards

[an error occurred while processing this directive]