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Gene set: V$POU1F1_Q6 (C3:TFAC:0358)
Standard nameV$POU1F1_Q6
Systematic nameC3:TFAC:0358
Brief descriptionGenes with 3'UTR containing motif ATGAATAAWT which matches annotation for POU1F1: POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA POU1F1b
 XX
 SY LSF-1; PUF-1; GHF-1.

XX
 OS rat, Rattus norvegicus
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; rodentia;
myomorpha; muridae; murinae
 XX
 XX
 CL C0007; POU; 3.1.2.1.1.2.

XX
 SZ 291 AA; 32.9 kDa (cDNA), 33-34.5 kDa (SDS) [25]

XX
 XX
 SC translated from EMBL #M23253
 XX
 FT 1
71 trans-activating domain.
 FT 2 87 serine-/threonine-rich
region (20/86).
 FT 124 198 PF00157; pou.
 FT 124 198 SM00352;
POU.
 FT 125 198 POU-specific domain.
 FT 214 273 POU homeo
domain.
 FT 214 276 SM00389; HOX.
 FT 215 271 PF00046; homeobox.

XX
 SF alternative splicing gives rise to a 26 AA insertion
after position 47
 SF leading to an altered trans-activation
domain in Pit-1a/GHF-2;
 SF Pit-1b is the predominant form
[7] [5];
 SF alternative translation initiation gives rise
to another product of 31 kDa
 SF [11];
 SF both POUs and
POUh contact DNA [17];
 SF POUh domain is sufficient for DNA-binding,
POUs and the linker region
 SF between POUs and POUh augment
in enhancing affinity and specificity [22]
 SF [17] [6];

SF POUs induces bending of the DNA [9];
 SF free in solution:
Pit-1 monomers or Pit-1/Oct-1 heterodimers, homodimers
 SF
form upon DNA-binding [17] [14];
 XX
 CP lactotrophs, somatotrophs
and thyrotrophs of anterior pituitary gland [25]
 CP [21] [18]

CN gonadotrophs of anterior pituitary gland, posterior pituitary,
heart,
 CN hypothalamus, kidney, liver, prostate, testis, thyroid
[25] [21] [18]
 XX
 FF tissue-specific activator [25] [22];

FF activates the genes for growth hormone (GH), prolactin (Prl)
and its own
 FF (GHF1) promoter [5];
 FF transcription of
the pit-1 gene is triggered by environmental stimuli that

FF enhance intracellular cAMP concentrations [20];
 FF autoregulation
through several promoter and enhancer elements [19] [20] [3];

FF may also be regulated through a potent vitamin D3 responsive
element [3];
 FF may be subject of differential cell-type specific
translational control
 FF [18];
 FF activity at the GH promoter
is counteracted by activin [4];
 FF synergistic action with
estrogen receptor at the Prl distal enhancer [18]
 FF and with
Ets-factors at the Prl promoter [1];
 FF the latter occurs
through a composite element where Pit-1 ensures
 FF tissue-specific
basal transcription and the Ets-like component mediates the

FF inducibility by hormones and/or growth factors [1];
 FF
phosphorylation in response to phorbol esters or cAMP decreases
the
 FF affinity to some Pit-1 elements, but increases that
to others [12];
 FF in general, binding to Prl and GH gene
sites is reduced, while interaction
 FF with binding sites
in TSH-beta is enhanced by 3-8-fold, most likely by
 FF shifting
the DNA-binding specificity from awwTatncat to awwAatncat [8];

FF thus, elevated cAMP levels inhibit Pit-1 activity on the Prl
gene [2];
 FF in contrast, a calcium-mediated pathway is used
by thyrotropin-releasing
 FF hormone (TRH) to enhance Prl and
TSH-beta expression [15] [2];
 XX
 XX
 XX
 XX

RN [1]; RE0004421.
 RX MEDLINE; 95403315.
 RA Howard P.
W., Maurer R. A.
 RT A composite Ets/Pit-1 binding site in
the prolactin gene can mediate
 RT transcriptional response
to multiple signal transduction pathways
 RL J. Biochem. 270:20930-20936
(1995).
 RN [2]; RE0004439.
 RX MEDLINE; 94216311.
 RA
Lew A. M., Yao H., Elsholtz H. P.
 RT Gia2- and G0a-mediated
signaling in the Pit-1-dependent inhibition of the
 RT prolactin
gene promoter
 RL J. Biol. Chem. 269:12007-12013 (1994).

RN [3]; RE0004438.
 RX MEDLINE; 93279469.
 RA Rhodes S.
J., Chen R., DiMattia G. E., Scully K. M., Kalla K. A., Lin

RA S.-C., Yu V. C., Rosenfeld M. G.
 RT A tissue-specific enhancer
confers Pit-1-dependent morphogen inducibility
 RT and autoregulation
on the pit-1 gene
 RL Genes Dev. 7:913-932 (1993).
 RN [4];
RE0002950.
 RX MEDLINE; 93087546.
 RA Struthers R. S., Gaddy-Kurten
D., Vale W. W.
 RT Activin inhibits binding of transcription
factor Pit-1 to the growth
 RT hormone promoter
 RL Proc.
Natl. Acad. Sci. USA 89:11451-11455 (1992).
 RN [5]; RE0003111.

RX MEDLINE; 92289691.
 RA Theill L. E., Hattori K., Lazzaro
D., Castrillo J.-L., Karin M.
 RT Differential splicing of
the GHF1 primary transcript gives rise to two
 RT functionally
distinct homeodomain proteins
 RL EMBO J. 11:2261-2269 (1992).

RN [6]; RE0004205.
 RX MEDLINE; 92123172.
 RA Aurora R.,
Herr W.
 RT Segments of the POU domain influence one another's
DNA-binding specificity
 RL Mol. Cell. Biol. 12:455-467 (1992).

RN [7]; RE0004420.
 RX MEDLINE; 92220611.
 RA Morris A.
E., Kloss B., McCesney R. E., Bancroft C., Chasin L. A.
 RT
An alternatively spliced Pit-1 isoform altered in its ability
to
 RT trans-activate
 RL Nucleic Acids Res. 20:1355-1361
(1992).
 RN [8]; RE0004435.
 RX MEDLINE; 92335213.
 RA
Steinfelder H. J., Wondisford F. E., Radovick S.
 RT Hormonal
regulation of the thyrotropin b-subunit gene by phosphorylation
of
 RT the pituitary-specific transcription factor PIT-1

RL Proc. Natl. Acad. Sci. USA 89:5942-5945 (1992).
 RN [9];
RE0000528.
 RX MEDLINE; 92007745.
 RA Verrijzer C. P., van
Oosterhout J. A. W. M., van Weperen W. W., van der
 RA Vliet
P. C.
 RT POU proteins bend DNA via the POU-specific domain

RL EMBO J. 10:3007-3014 (1991).
 RN [10]; RE0002474.
 RX
MEDLINE; 91195306.
 RA Steinfelder H. J., Hauser P., Nakayama
Y., Radovick S., McClaskey J. H.,
 RA Taylor T., Weintraub
B. D., Wondisford F. E.
 RT Thyrotropin-releasing hormone regulation
of human TSHB expression: Role of
 RT a pituitary-specific
transcription factor (Pit-1/GHF-1) and potential
 RT interaction
with a thyroid hormone-inhibitory element
 RL Proc. Natl. Acad.
Sci. USA 88:3130-3134 (1991).
 RN [11]; RE0004428.
 RX MEDLINE;
91302290.
 RA Voss J. W., Yao T.-P., Rosenfeld M. G.
 RT
Alternative translation initiation site usage results in two structurally

RT distinct forms of Pit-1
 RL J. Biol. Chem. 266:12832-12835
(1991).
 RN [12]; RE0004430.
 RX MEDLINE; 91343911.

RA Kapiloff M. S., Farkash Y., Wegner M., Rosenfeld M. G.

RT Variable effects of phosphorylation of Pit-1 dictated by the
DNA response
 RT elements
 RL Science 253:789-789 (1991).

RN [13]; RE0004431.
 RX MEDLINE; 92140406.
 RA Hoggard N.,
Davis J. R. E., Berwaer M., Monget P., Peers B., Belayew A.,

RA Martial J. A.
 RT Pit-1 binding sequences permit calcium
regulation of human prolactin gene
 RT expression
 RL Mol.
Endocrinol. 5:1748-1754 (1991).
 RN [14]; RE0004432.
 RX
MEDLINE; 91293590.
 RA Voss J. W., Wilson L., Rosenfeld M.
G.
 RT POU-domain proteins Pit-1 and Oct-1 interact to form
a heteromeric complex
 RT and can cooperate to induce expression
of the prolactin promoter
 RL Genes Dev. 5:1309-1320 (1991).

RN [15]; RE0004445.
 RX MEDLINE; 92130998.
 RA Yan G. Z.,
Bancroft C.
 RT Mediation by calcium of thyrotropin--releasing
hormone action on the
 RT prolactin promoter via transcription
factor pit-1
 RL Mol. Endocrinol. 5:1488-1497 (1991).
 RN
[16]; RE0000616.
 RX MEDLINE; 90169515.
 RA Elsholtz H.
P., Albert V. R., Treacy M. N., Rosenfeld M. G.
 RT A two-base
change in a POU factor-binding site switches pituitary-specific

RT to lymphoid-specific gene expression
 RL Genes Dev. 4:43-51
(1990).
 RN [17]; RE0002735.
 RX MEDLINE; 90275599.

RA Ingraham H. A., Flynn S. E., Voss J. W., Albert V. R., Kapiloff
M. S.,
 RA Wilson L., Rosenfeld M. G.
 RT The POU-specific
domain of Pit-1 is essential for sequence-specific, high
 RT
affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions

RL Cell 61:1021-1033 (1990).
 RN [18]; RE0003182.
 RX MEDLINE;
90337309.
 RA Simmons D.M., Voss J.W., Ingraham H.A., Holloway
J.M., Broide R.S.,
 RA Rosenfeld M.G., Swanson L.W.
 RT
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation
and
 RT synergistic interactions with other classes of transcription
factors
 RL Genes Dev. 4:695-711 (1990).
 RN [19]; RE0004424.

RX MEDLINE; 90332047.
 RA Chen R., Ingraham H. A., Treacy M.
N., Albert V. R., Wilson L., Rosenfeld
 RA M. G.
 RT Autoregulation
of pit-1 gene expression mediated by two cis-active promoter

RT elements
 RL Nature 346:583-586 (1990).
 RN [20]; RE0004427.

RX MEDLINE; 90294931.
 RA McCormick A., Brady H., Theill L.
E., Karin M.
 RT Regulation of the pituitary-specific homeobox
gene GHF1 by cell-autonomous
 RT and environmental cues

RL Nature 345:829-832 (1990).
 RN [21]; RE0000645.
 RX MEDLINE;
89378742.
 RA Mangalam H. J., Albert V. R., Ingraham H. A.,
Kapiloff M., Wilson L.,
 RA Nelson Ch., Elsholtz H., Rosenfeld
M. G.
 RT A pituitary POU domain protein, Pit-1, activates
both growth hormone and
 RT prolactin promoters transcriptionally

RL Genes Dev. 3:946-958 (1989).
 RN [22]; RE0001790.
 RX
MEDLINE; 90081880.
 RA Theill L. E., Castrillo J.-L., Wu D.,
Karin M.
 RT Dissection of functional domains of the pituitary-specific
transcription
 RT factor GHF-1
 RL Nature 342:945-948 (1989).

RN [23]; RE0002021.
 RX MEDLINE; 89240028.
 RA Sharp Z.
D., Helsel S., Cao Z., Barron E. A., Sanchez Y.
 RT DNA recognition
element required for PUF-I mediated cell-type specific
 RT
transcription of the rat prolactin gene
 RL Nucleic Acids Res.
17:2705-2722 (1989).
 RN [24]; RE0002639.
 RX MEDLINE; 89130154.

RA Castrillo J.-L., Bodner M., Karin M.
 RT Purification of
growth hormone-specific transcription factor GHF-1
 RT containing
homeobox
 RL Science 243:814-817 (1989).
 RN [25]; RE0000076.

RX MEDLINE; 89028661.
 RA Ingraham H. A., Chen R., Mangalam
H. J., Elsholtz H. P., Flynn S. E., Lin
 RA C. R., Simmons
D. M., Swanson L., Rosenfeld M. G.
 RT A tissue-specific transcription
factor containing a homeodomain specifies a
 RT pituitary phenotype

RL Cell 55:519-529 (1988).
 RN [26]; RE0002599.
 RX MEDLINE;
88159230.
 RA Nelson C., Albert V. R., Elsholtz H. P., Lu L.
I.-W., Rosenfeld M. G.
 RT Activation of cell-specific expression
of rat growth hormone and prolactin
 RT genes by a common transcription
factor
 RL Science 239:1400-1405 (1988).
 RN [27]; RE0000072.

RX MEDLINE; 87244342.
 RA Bodner M., Karin M.
 RT A Pituitary-Specific
Trans-Acting Factor Can Stimulate Transcription from
 RT the
Growth Hormone Promoter in Extracts of Nonexpressing Cells

RL Cell 50:267-275 (1987).
 RN [28]; RE0000347.
 RX MEDLINE;
87246534.
 RA Lefevre C., Imagawa M., Dana S., Grindlay J.,
Bodner M., Karin M.
 RT Tissue-specific expression of the human
growth hormone gene is conferred in
 RT part by the binding
of a specific trans-acting factor
 RL EMBO J. 6:971-981 (1987).

RN [29]; RE0001331.
 RX MEDLINE; 88065474.
 RA Cao Z., Barron
E. A., Carillo A. J., Sharp Z. D.
 RT Reconstitution of Cell-Type-Specific
Transcription of the Rat Prolactin
 RT Gene In Vitro
 RL
Mol. Cell. Biol. 7:3402-3408 (1987).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

242 genes, 242 accessions (Toggle view)

AccessionGeneTitleLinks
FZD8FZD8frizzled homolog 8 (Drosophila)Source|GeneCards
RTN3RTN3reticulon 3Source|GeneCards
GH1GH1growth hormone 1Source|GeneCards
SOX4SOX4SRY (sex determining region Y)-box 4Source|GeneCards
FOXD3FOXD3forkhead box D3Source|GeneCards
CD68CD68CD68 antigenSource|GeneCards
TLE3TLE3transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)Source|GeneCards
HESX1HESX1homeo box (expressed in ES cells) 1Source|GeneCards
GPC3GPC3glypican 3Source|GeneCards
SIAT9SIAT9sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)Source|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
NRP1NRP1Neuropilin 1Source|GeneCards
FLJ20257BCDIN3bin3, bicoid-interacting 3, homolog (Drosophila)Source|GeneCards
NHLH1NHLH1nescient helix loop helix 1Source|GeneCards
ZNF593ZNF593zinc finger protein 593Source|GeneCards
MEIS2MEIS2Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)Source|GeneCards
KRT20KRT20keratin 20Source|GeneCards
GW112OLFM4olfactomedin 4Source|GeneCards
FLJ25323FLJ25323FLJ25323 proteinSource|GeneCards
NPM3NPM3nucleophosmin/nucleoplasmin, 3Source|GeneCards
RTN4RTN4reticulon 4Source|GeneCards
CSH2CSH2Chorionic somatomammotropin hormone 2Source|GeneCards
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)Source|GeneCards
RAI17RAI17retinoic acid induced 17Source|GeneCards
GAP43GAP43growth associated protein 43Source|GeneCards
SLC25A26SLC25A26solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26Source|GeneCards
CSH1CSH1chorionic somatomammotropin hormone 1 (placental lactogen)Source|GeneCards
ZHX1ZHX1zinc-fingers and homeoboxes 1Source|GeneCards
DIO2DIO2deiodinase, iodothyronine, type IISource|GeneCards
STOML2STOML2stomatin (EPB72)-like 2Source|GeneCards
HUCEP11TMCC2transmembrane and coiled-coil domain family 2Source|GeneCards
DLGAP4DLGAP4discs, large (Drosophila) homolog-associated protein 4Source|GeneCards
LIN28LIN28lin-28 homolog (C. elegans)Source|GeneCards
SESN3SESN3sestrin 3Source|GeneCards
RNPC2RNPC2RNA-binding region (RNP1, RRM) containing 2Source|GeneCards
FLJ36031FLJ36031hypothetical protein FLJ36031Source|GeneCards
ANK3ANK3ankyrin 3, node of Ranvier (ankyrin G)Source|GeneCards
TIAL1TIAL1TIA1 cytotoxic granule-associated RNA binding protein-like 1Source|GeneCards
C1ORF25C1ORF25chromosome 1 open reading frame 25Source|GeneCards
FLJ14888WDR73WD repeat domain 73Source|GeneCards
STAC2STAC2SH3 and cysteine rich domain 2Source|GeneCards
TRPM8TRPM8transient receptor potential cation channel, subfamily M, member 8Source|GeneCards
PRKAA1PRKAA1Protein kinase, AMP-activated, alpha 1 catalytic subunitSource|GeneCards
FLJ31846FLJ31846hypothetical protein FLJ31846Source|GeneCards
TMIETMIEtransmembrane inner ear proteinSource|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
THBS2THBS2thrombospondin 2Source|GeneCards
RRAGARRAGARas-related GTP binding ASource|GeneCards
ANKRD3RIPK4receptor-interacting serine-threonine kinase 4Source|GeneCards
DC12DC12DC12 proteinSource|GeneCards
DKFZP547C176ELMOD1ELMO domain containing 1Source|GeneCards
FLJ11752SCYL1BP1SCY1-like 1 binding protein 1Source|GeneCards
VGFVGFVGF nerve growth factor inducibleSource|GeneCards
UHRF1UHRF1ubiquitin-like, containing PHD and RING finger domains, 1Source|GeneCards
SIX1SIX1sine oculis homeobox homolog 1 (Drosophila)Source|GeneCards
LOC220032LOC220032GDPD domain containing proteinSource|GeneCards
FLJ39458SAMD12Sterile alpha motif domain containing 12Source|GeneCards
EPOEPOerythropoietinSource|GeneCards
FLJ44313FLJ44313FLJ44313 proteinSource|GeneCards
MYH2MYH2myosin, heavy polypeptide 2, skeletal muscle, adultSource|GeneCards
DPYDDPYDdihydropyrimidine dehydrogenaseSource|GeneCards
FBXW7FBXW7F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)Source|GeneCards
CYP46A1CYP46A1cytochrome P450, family 46, subfamily A, polypeptide 1Source|GeneCards
TPH2TPH2tryptophan hydroxylase 2Source|GeneCards
APBB1APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)Source|GeneCards
SKP1ASKP1AS-phase kinase-associated protein 1A (p19A)Source|GeneCards
ZA20D1ZA20D1zinc finger, A20 domain containing 1Source|GeneCards
HOXD10HOXD10homeo box D10Source|GeneCards
DICER1DICER1Dicer1, Dcr-1 homolog (Drosophila)Source|GeneCards
PURAPURApurine-rich element binding protein ASource|GeneCards
HOXC6HOXC6homeo box C6Source|GeneCards
UBE4BUBE4Bubiquitination factor E4B (UFD2 homolog, yeast)Source|GeneCards
FLJ22582BAIAP2L2BAI1-associated protein 2-like 2Source|GeneCards
CACNA1DCACNA1Dcalcium channel, voltage-dependent, L type, alpha 1D subunitSource|GeneCards
PIAS1PIAS1protein inhibitor of activated STAT, 1Source|GeneCards
EBF2EBF2early B-cell factor 2Source|GeneCards
PHOX2BPHOX2Bpaired-like homeobox 2bSource|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
DUSP9DUSP9dual specificity phosphatase 9Source|GeneCards
GBX2GBX2gastrulation brain homeo box 2Source|GeneCards
CNTNAP5CNTNAP5Contactin associated protein-like 5Source|GeneCards
DKFZP762A217DKFZP762A217hypothetical protein DKFZp762A217Source|GeneCards
MGC4796STK40serine/threonine kinase 40Source|GeneCards
DLX1DLX1distal-less homeo box 1Source|GeneCards
SMPXSMPXsmall muscle protein, X-linkedSource|GeneCards
SYT14LSYT14Lsynaptotagmin XIV-likeSource|GeneCards
IDN3NIPBLNipped-B homolog (Drosophila)Source|GeneCards
ZIC5ZIC5Zic family member 5 (odd-paired homolog, Drosophila)Source|GeneCards
EIF4EEIF4Eeukaryotic translation initiation factor 4ESource|GeneCards
TIAF1TIAF1TGFB1-induced anti-apoptotic factor 1Source|GeneCards
P518P518P518 precursor proteinSource|GeneCards
FLJ10945FLJ10945hypothetical protein FLJ10945Source|GeneCards
PRDM8PRDM8PR domain containing 8Source|GeneCards
CNTNAP4CNTNAP4contactin associated protein-like 4Source|GeneCards
FLJ39075FLJ39075hypothetical protein FLJ39075Source|GeneCards
IL21IL21Interleukin 21Source|GeneCards
IARSIARSisoleucine-tRNA synthetaseSource|GeneCards
SKILSKILSKI-likeSource|GeneCards
PRLPRLprolactinSource|GeneCards
FLRT3FLRT3fibronectin leucine rich transmembrane protein 3Source|GeneCards
BACE2BACE2beta-site APP-cleaving enzyme 2Source|GeneCards
ZNF384ZNF384zinc finger protein 384Source|GeneCards
PDZRN4PDZRN4PDZ domain containing RING finger 4Source|GeneCards
PCSK5PCSK5proprotein convertase subtilisin/kexin type 5Source|GeneCards
FLJ22386FLJ22386leucine zipper domain proteinSource|GeneCards
IL3IL3interleukin 3 (colony-stimulating factor, multiple)Source|GeneCards
SYT12SYT12synaptotagmin XIISource|GeneCards
GR6GR6putative GR6 proteinSource|GeneCards
SLC26A8SLC26A8solute carrier family 26, member 8Source|GeneCards
ZNF423ZNF423zinc finger protein 423Source|GeneCards
FOXP2FOXP2forkhead box P2Source|GeneCards
COMMD10COMMD10COMM domain containing 10Source|GeneCards
POU2F1POU2F1POU domain, class 2, transcription factor 1Source|GeneCards
KIAA1404KIAA1404KIAA1404 proteinSource|GeneCards
C1ORF26C1ORF26chromosome 1 open reading frame 26Source|GeneCards
EN1EN1engrailed homolog 1Source|GeneCards
ZNF238ZNF238zinc finger protein 238Source|GeneCards
HOXB5HOXB5homeo box B5Source|GeneCards
CPNE1CPNE1RNA binding motif protein 12Source|GeneCards
MGC34761MGC34761Hypothetical protein MGC34761Source|GeneCards
MAP3K13MAP3K13mitogen-activated protein kinase kinase kinase 13Source|GeneCards
CREB5CREB5cAMP responsive element binding protein 5Source|GeneCards
RHODRHODras homolog gene family, member DSource|GeneCards
FGF12FGF12fibroblast growth factor 12Source|GeneCards
FLJ33651FLJ33651hypothetical protein FLJ33651Source|GeneCards
EN2EN2engrailed homolog 2Source|GeneCards
CASQ2CASQ2calsequestrin 2 (cardiac muscle)Source|GeneCards
PTPRDPTPRDprotein tyrosine phosphatase, receptor type, DSource|GeneCards
RORARORARAR-related orphan receptor ASource|GeneCards
HH114HH114hypothetical protein HH114Source|GeneCards
KRT25DKRT25Dtype I inner root sheath specific keratin 25 irs4Source|GeneCards
SALL3SALL3sal-like 3 (Drosophila)Source|GeneCards
STK32CSTK32Cserine/threonine kinase 32CSource|GeneCards
TFAP2BL1TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta)Source|GeneCards
AQP3AQP3aquaporin 3Source|GeneCards
SP6SP6Sp6 transcription factorSource|GeneCards
SARS2SARS2seryl-tRNA synthetase 2Source|GeneCards
MRPL17MRPL17mitochondrial ribosomal protein L17Source|GeneCards
PIK3R3PIK3R3phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)Source|GeneCards
ZNF579ZNF579zinc finger protein 579Source|GeneCards
PRKAG1PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunitSource|GeneCards
BMP4BMP4bone morphogenetic protein 4Source|GeneCards
PCF11PCF11pre-mRNA cleavage complex II protein Pcf11Source|GeneCards
LOC147991DPY19L3dpy-19-like 3 (C. elegans)Source|GeneCards
RORBRORBRAR-related orphan receptor BSource|GeneCards
HIVEP1HIVEP1human immunodeficiency virus type I enhancer binding protein 1Source|GeneCards
DIAPH1DIAPH1diaphanous homolog 1 (Drosophila)Source|GeneCards
BZW2BZW2basic leucine zipper and W2 domains 2Source|GeneCards
LOC283932LOC283932hypothetical protein LOC283932Source|GeneCards
PRKCHPRKCHprotein kinase C, etaSource|GeneCards
TNFRSF12ATNFRSF12Atumor necrosis factor receptor superfamily, member 12ASource|GeneCards
TBR1TBR1T-box, brain, 1Source|GeneCards
GRK6GRK6G protein-coupled receptor kinase 6Source|GeneCards
MYL1MYL1myosin, light polypeptide 1, alkali; skeletal, fastSource|GeneCards
FLJ14800FLJ14800hypothetical protein FLJ14800Source|GeneCards
SFRS14SFRS14splicing factor, arginine/serine-rich 14Source|GeneCards
C14ORF138C14ORF138chromosome 14 open reading frame 138Source|GeneCards
PDE2APDE2Aphosphodiesterase 2A, cGMP-stimulatedSource|GeneCards
PRIMA1PRIMA1proline rich membrane anchor 1Source|GeneCards
ASF1AASF1AASF1 anti-silencing function 1 homolog A (S. cerevisiae)Source|GeneCards
TYRO3TYRO3TYRO3 protein tyrosine kinaseSource|GeneCards
IL5IL5interleukin 5 (colony-stimulating factor, eosinophil)Source|GeneCards
C20ORF46C20ORF46chromosome 20 open reading frame 46Source|GeneCards
ANKMY2ANKMY2ankyrin repeat and MYND domain containing 2Source|GeneCards
CALCRCALCRcalcitonin receptorSource|GeneCards
MAPK9MAPK9mitogen-activated protein kinase 9Source|GeneCards
GATA6GATA6GATA binding protein 6Source|GeneCards
CSHL1CSHL1chorionic somatomammotropin hormone-like 1Source|GeneCards
CYFIP2CYFIP2cytoplasmic FMR1 interacting protein 2Source|GeneCards
INHBAINHBAinhibin, beta A (activin A, activin AB alpha polypeptide)Source|GeneCards
HSPC152HSPC152hypothetical protein HSPC152Source|GeneCards
MYBPC1MYBPC1myosin binding protein C, slow typeSource|GeneCards
KIAA0555KIAA0555KIAA0555 gene productSource|GeneCards
FCHSD1FCHSD1FCH and double SH3 domains 1Source|GeneCards
PTHLHPTHLHparathyroid hormone-like hormoneSource|GeneCards
IGSF4IGSF4immunoglobulin superfamily, member 4Source|GeneCards
ESRRGESRRGestrogen-related receptor gammaSource|GeneCards
DCXDCXdoublecortex; lissencephaly, X-linked (doublecortin)Source|GeneCards
VGLL4VGLL4vestigial like 4 (Drosophila)Source|GeneCards
SLC37A2SLC37A2solute carrier family 37 (glycerol-3-phosphate transporter), member 2Source|GeneCards
LOC338773LOC338773hypothetical protein LOC338773Source|GeneCards
FLJ31461FLJ31461hypothetical protein FLJ31461Source|GeneCards
SLITRK1SLITRK1SLIT and NTRK-like family, member 1Source|GeneCards
HT007HT007uncharacterized hypothalamus protein HT007Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
LOC92162LOC92162similar to RIKEN cDNA 2600017H02Source|GeneCards
ZIC1ZIC1Zic family member 1 (odd-paired homolog, Drosophila)Source|GeneCards
HOXA5HOXA5homeo box A5Source|GeneCards
KIAA1727KIAA1727KIAA1727 proteinSource|GeneCards
RNF12RNF12ring finger protein 12Source|GeneCards
FLJ10925FLJ10925hypothetical protein FLJ10925Source|GeneCards
ZIC4ZIC4Zic family member 4Source|GeneCards
JAG1JAG1jagged 1 (Alagille syndrome)Source|GeneCards
MGC19595ARMC6armadillo repeat containing 6Source|GeneCards
SPTBSPTBspectrin, beta, erythrocytic (includes spherocytosis, clinical type I)Source|GeneCards
SMAD1SMAD1SMAD, mothers against DPP homolog 1 (Drosophila)Source|GeneCards
NAALADL2NAALADL2N-acetylated alpha-linked acidic dipeptidase 2Source|GeneCards
MRPS12MRPS12mitochondrial ribosomal protein S12Source|GeneCards
SEPHS1SEPHS1selenophosphate synthetase 1Source|GeneCards
CRIM1CRIM1cysteine-rich motor neuron 1Source|GeneCards
CDC42EP3CDC42EP3CDC42 effector protein (Rho GTPase binding) 3Source|GeneCards
ZIC2ZIC2Zic family member 2 (odd-paired homolog, Drosophila)Source|GeneCards
MLLT7MLLT7myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7Source|GeneCards
FLJ20345FLJ20345hypothetical protein FLJ20345Source|GeneCards
H2AFY2H2AFY2H2A histone family, member Y2Source|GeneCards
BCAR3BCAR3breast cancer anti-estrogen resistance 3Source|GeneCards
SLITRK4SLITRK4SLIT and NTRK-like family, member 4Source|GeneCards
FGF9FGF9fibroblast growth factor 9 (glia-activating factor)Source|GeneCards
CHRNA10CHRNA10cholinergic receptor, nicotinic, alpha polypeptide 10Source|GeneCards
MGC35440MGC35440hypothetical protein MGC35440Source|GeneCards
RUNX1RUNX1runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)Source|GeneCards
GPR88GPR88G-protein coupled receptor 88Source|GeneCards
NPHP4NPHP4nephronophthisis 4Source|GeneCards
LIMPDLIM5PDZ and LIM domain 5Source|GeneCards
MAP2MAP2microtubule-associated protein 2Source|GeneCards
OTPOTPorthopedia homolog (Drosophila)Source|GeneCards
MYO15AMYO15Amyosin XVASource|GeneCards
FLJ23342FLJ23342hypothetical protein FLJ23342Source|GeneCards
TRPS1TRPS1trichorhinophalangeal syndrome ISource|GeneCards
DLSTDLSTdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)Source|GeneCards
ADAMTS5ADAMTS5a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)Source|GeneCards
LMNALMNAlamin A/CSource|GeneCards
USH3AUSH3AUsher syndrome 3ASource|GeneCards
BNC2BNC2basonuclin 2Source|GeneCards
WNT11WNT11wingless-type MMTV integration site family, member 11Source|GeneCards
ZCWPW1ZCWPW1zinc finger, CW-type with PWWP domain 1Source|GeneCards
OTX2OTX2orthodenticle homolog 2 (Drosophila)Source|GeneCards
KCTD8KCTD8potassium channel tetramerisation domain containing 8Source|GeneCards
PRDX5PRDX5peroxiredoxin 5Source|GeneCards
MYO1CMYO1Cmyosin ICSource|GeneCards
OA48-18
DOCK7DOCK7dedicator of cytokinesis 7Source|GeneCards
PKP4PKP4plakophilin 4Source|GeneCards
FMNL1FMNL1formin-like 1Source|GeneCards
CACNG2CACNG2calcium channel, voltage-dependent, gamma subunit 2Source|GeneCards
ATRNL1ATRNL1attractin-like 1Source|GeneCards
SOX14SOX14SRY (sex determining region Y)-box 14Source|GeneCards
PPOXPPOXprotoporphyrinogen oxidaseSource|GeneCards
STMN2STMN2stathmin-like 2Source|GeneCards
TDRD5TDRD5tudor domain containing 5Source|GeneCards
GTPBP1GTPBP1GTP binding protein 1Source|GeneCards

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