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Gene set: V$RSRFC4_01 (C3:TFAC:0013)
Standard nameV$RSRFC4_01
Systematic nameC3:TFAC:0013
Brief descriptionGenes with 3'UTR containing motif RNKCTATTTWTAGMWN which matches annotation for MEF2A: MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
XX
XX
FA RSRFC4
XX
SY RSRFC4.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; primates
XX
XX
CL C0014; MADS; 4.4.1.1.1.3.
XX
SZ 497 AA; 53.6 kDa (cDNA)
XX
XX
SC conceptually translated from EMBL/GenBank/DDBJ #X63381
XX
FT 1 28 DNA binding specificity.
FT 1 105 DNA binding domain.
FT 1 59 PF00319; SRF-TF.
FT 1 60 SM00432; MADS.
FT 2 57 MADS box.
FT 87 130 replaced by 87-130 in RSRFC9.
XX
SF splice variants are MEF-2, aMEF-2, and RSRFC9 [2] [1];
SF no stable heterodimers with SRF [2];
XX
CP ubiquitous (adult) [1]
CN fetal skeletal muscle [1]
XX
FF although RSRFC4 binding sequences can act as promoter elements in
FF transfection assays, co-transfection with RSRFC4 does not lead to
FF additional transcriptional activation [2]
XX
IN T01785; MEF-2B-1; mouse, Mus musculus.
IN T01012; MEF-2B; human, Homo sapiens.
IN T01009; RSRFC4; human, Homo sapiens.
XX
XX
XX
XX
RN [1]; RE0000768.
RX MEDLINE; 92387551.
RA Yu Y.-T., Breitbart R. E., Smoot L. B., Lee Y., Mahdavi V., Nadal-Ginard B.
RT Human myocyte-specific enhancer factor 2 comprises a group of
RT tissue-restricted MADS box transcription factors
RL Genes Dev. 6:1783-1798 (1992).
RN [2]; RE0000769.
RX MEDLINE; 92084105.
RA Pollock R., Treisman R.
RT Human SRF-related proteins: DNA-binding properties and potential regulatory
RT targets
RL Genes Dev. 5:2327-2341 (1991).
XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

251 genes, 251 accessions (Toggle view)

AccessionGeneTitleLinks
ATF3ATF3activating transcription factor 3Source|GeneCards
TM4SF13TSPAN13tetraspanin 13Source|GeneCards
ZNF533ZNF533Zinc finger protein 533Source|GeneCards
FLJ90637C1ORF118chromosome 1 open reading frame 118Source|GeneCards
ARHGAP26ARHGAP26Rho GTPase activating protein 26Source|GeneCards
CYP2E1CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1Source|GeneCards
PAK6PAK6p21(CDKN1A)-activated kinase 6Source|GeneCards
PLAGL2PLAGL2pleiomorphic adenoma gene-like 2Source|GeneCards
SLC9A5SLC9A5solute carrier family 9 (sodium/hydrogen exchanger), isoform 5Source|GeneCards
FBXO40FBXO40F-box protein 40Source|GeneCards
LECT1LECT1leukocyte cell derived chemotaxin 1Source|GeneCards
GPC4GPC4glypican 4Source|GeneCards
PDLIM1PDLIM1PDZ and LIM domain 1 (elfin)Source|GeneCards
EXTL1EXTL1exostoses (multiple)-like 1Source|GeneCards
PPP2R3APPP2R3Aprotein phosphatase 2 (formerly 2A), regulatory subunit B'', alphaSource|GeneCards
SCA1ATXN1ataxin 1Source|GeneCards
URPUNC50unc-50 homolog (C. elegans)Source|GeneCards
ACTA1ACTA1actin, alpha 1, skeletal muscleSource|GeneCards
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)Source|GeneCards
DKK2DKK2dickkopf homolog 2 (Xenopus laevis)Source|GeneCards
ZHX2ZHX2transcription factor ZHX2Source|GeneCards
ACTCACTCactin, alpha, cardiac muscleSource|GeneCards
FLJ20152FLJ20152hypothetical protein FLJ20152Source|GeneCards
RG9MTD2RG9MTD2RNA (guanine-9-) methyltransferase domain containing 2Source|GeneCards
PPP1R3DPPP1R3Dprotein phosphatase 1, regulatory subunit 3DSource|GeneCards
FLJ32447FLJ32447hypothetical protein FLJ32447Source|GeneCards
SLC26A6SLC26A6solute carrier family 26, member 6Source|GeneCards
HRMT1L3HRMT1L3HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae)Source|GeneCards
STOML2STOML2stomatin (EPB72)-like 2Source|GeneCards
CPEB4CPEB4cytoplasmic polyadenylation element binding protein 4Source|GeneCards
MAB21L2MAB21L2mab-21-like 2 (C. elegans)Source|GeneCards
ITGB3BPITGB3BPintegrin beta 3 binding protein (beta3-endonexin)Source|GeneCards
ARHGEF15ARHGEF15Rho guanine nucleotide exchange factor (GEF) 15Source|GeneCards
FLJ45832FLJ45832FLJ45832 proteinSource|GeneCards
SH3GLB2SH3GLB2SH3-domain GRB2-like endophilin B2Source|GeneCards
FLJ25476FLJ25476FLJ25476 proteinSource|GeneCards
EYA1EYA1eyes absent homolog 1 (Drosophila)Source|GeneCards
MYH3MYH3myosin, heavy polypeptide 3, skeletal muscle, embryonicSource|GeneCards
ITGA7ITGA7integrin, alpha 7Source|GeneCards
DTNBDTNBdystrobrevin, betaSource|GeneCards
ZFPM2ZFPM2zinc finger protein, multitype 2Source|GeneCards
RICSRICSRho GTPase-activating proteinSource|GeneCards
ESAMESAMendothelial cell adhesion moleculeSource|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
CENTD1CENTD1centaurin, delta 1Source|GeneCards
THBS2THBS2thrombospondin 2Source|GeneCards
RAB2RAB2RAB2, member RAS oncogene familySource|GeneCards
NR4A1NR4A1nuclear receptor subfamily 4, group A, member 1Source|GeneCards
KCNN1KCNN1potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1Source|GeneCards
SIPA1L1SIPA1L1signal-induced proliferation-associated 1 like 1Source|GeneCards
LOC161247LOC161247similar to CG10671-likeSource|GeneCards
FBXW11FBXW11F-box and WD-40 domain protein 11Source|GeneCards
SLC8A3SLC8A3solute carrier family 8 (sodium-calcium exchanger), member 3Source|GeneCards
LRRTM4LRRTM4leucine-rich repeat transmembrane neuronal 4 proteinSource|GeneCards
CAV3CAV3caveolin 3Source|GeneCards
TMEPAITMEPAItransmembrane, prostate androgen induced RNASource|GeneCards
DGKIDGKIdiacylglycerol kinase, iotaSource|GeneCards
ADCY2ADCY2adenylate cyclase 2 (brain)Source|GeneCards
HIST1H2AAHIST1H2AAhistone 1, H2aaSource|GeneCards
SIAT7ESIAT7Esialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) ESource|GeneCards
SLCO3A1SLCO3A1solute carrier organic anion transporter family, member 3A1Source|GeneCards
SMARCA2SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2Source|GeneCards
ZNF216ZA20D2zinc finger, A20 domain containing 2Source|GeneCards
RGS3RGS3regulator of G-protein signalling 3Source|GeneCards
SCML1SCML1sex comb on midleg-like 1 (Drosophila)Source|GeneCards
EPHA7EPHA7EphA7Source|GeneCards
NDRG2NDRG2NDRG family member 2Source|GeneCards
NR2F1NR2F1nuclear receptor subfamily 2, group F, member 1Source|GeneCards
TWIST1TWIST1twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)Source|GeneCards
FLJ31951FLJ31951hypothetical protein FLJ31951Source|GeneCards
STACSTACsrc homology three (SH3) and cysteine rich domainSource|GeneCards
ZNF143ZNF143zinc finger protein 143 (clone pHZ-1)Source|GeneCards
DLX5DLX5distal-less homeo box 5Source|GeneCards
PTPROPTPROprotein tyrosine phosphatase, receptor type, OSource|GeneCards
GPR153GPR153G protein-coupled receptor 153Source|GeneCards
MEOX2MEOX2mesenchyme homeo box 2 (growth arrest-specific homeo box)Source|GeneCards
PYYPYYpeptide YYSource|GeneCards
PTCHPTCHpatched homolog (Drosophila)Source|GeneCards
KTN1KTN1kinectin 1 (kinesin receptor)Source|GeneCards
SSH3SSH3slingshot homolog 3 (Drosophila)Source|GeneCards
FLJ38608FLJ38608hypothetical protein FLJ38608Source|GeneCards
ZNF161ZNF161zinc finger protein 161Source|GeneCards
CA7CA7carbonic anhydrase VIISource|GeneCards
MYOZ2MYOZ2myozenin 2Source|GeneCards
TP73LTP73Ltumor protein p73-likeSource|GeneCards
DNAJA4DNAJA4DnaJ (Hsp40) homolog, subfamily A, member 4Source|GeneCards
SMPXSMPXsmall muscle protein, X-linkedSource|GeneCards
ESR1ESR1estrogen receptor 1Source|GeneCards
SLAMF1SLAMF1signaling lymphocytic activation molecule family member 1Source|GeneCards
TNNC1TNNC1troponin C type 1 (slow)Source|GeneCards
PAX3PAX3paired box gene 3 (Waardenburg syndrome 1)Source|GeneCards
TOB2TOB2transducer of ERBB2, 2Source|GeneCards
ENO3ENO3enolase 3, (beta, muscle)Source|GeneCards
CLDN14CLDN14claudin 14Source|GeneCards
CUL3CUL3cullin 3Source|GeneCards
MIG12MID1IP1MID1 interacting protein 1 (gastrulation specific G12-like (zebrafish))Source|GeneCards
PRDM1PRDM1PR domain containing 1, with ZNF domainSource|GeneCards
HRASLSHRASLSHRAS-like suppressorSource|GeneCards
HAPLN1HAPLN1hyaluronan and proteoglycan link protein 1Source|GeneCards
SOX5SOX5SRY (sex determining region Y)-box 5Source|GeneCards
FLJ20811ARMCX6armadillo repeat containing, X-linked 6Source|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
C21ORF29C21ORF29chromosome 21 open reading frame 29Source|GeneCards
HFE2HFE2Hemochromatosis type 2 (juvenile)Source|GeneCards
SLC26A9SLC26A9solute carrier family 26, member 9Source|GeneCards
CYP26B1CYP26B1cytochrome P450, family 26, subfamily B, polypeptide 1Source|GeneCards
CNTN1CNTN1contactin 1Source|GeneCards
TGFB1I4TSC22D1TSC22 domain family, member 1Source|GeneCards
EDG1EDG1endothelial differentiation, sphingolipid G-protein-coupled receptor, 1Source|GeneCards
PANK1PANK1pantothenate kinase 1Source|GeneCards
RAP2CRAP2CRAP2C, member of RAS oncogene familySource|GeneCards
CSPG3CSPG3chondroitin sulfate proteoglycan 3 (neurocan)Source|GeneCards
HAO1HAO1hydroxyacid oxidase (glycolate oxidase) 1Source|GeneCards
RBMS3RBMS3RNA binding motif, single stranded interacting proteinSource|GeneCards
FLJ33069TMEM71transmembrane protein 71Source|GeneCards
HAS2HAS2hyaluronan synthase 2Source|GeneCards
SMCR7SMCR7Smith-Magenis syndrome chromosome region, candidate 7Source|GeneCards
ALS2CR3ALS2CR3amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3Source|GeneCards
ADAM23ADAM23ADAM metallopeptidase domain 23Source|GeneCards
CSRP3CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)Source|GeneCards
HOXB4HOXB4homeo box B4Source|GeneCards
DLG2DLG2Discs, large homolog 2, chapsyn-110 (Drosophila)Source|GeneCards
TCEA3TCEA3transcription elongation factor A (SII), 3Source|GeneCards
ZNF238ZNF238zinc finger protein 238Source|GeneCards
KBTBD5KBTBD5kelch repeat and BTB (POZ) domain containing 5Source|GeneCards
ELMO1ELMO1engulfment and cell motility 1 (ced-12 homolog, C. elegans)Source|GeneCards
ART5ART5ADP-ribosyltransferase 5Source|GeneCards
CASQ1CASQ1calsequestrin 1 (fast-twitch, skeletal muscle)Source|GeneCards
KIAA0999KIAA0999KIAA0999 proteinSource|GeneCards
ARR3ARR3arrestin 3, retinal (X-arrestin)Source|GeneCards
SMYD1SMYD1SET and MYND domain containing 1Source|GeneCards
FGF12FGF12fibroblast growth factor 12Source|GeneCards
FLJ13725FAM65Afamily with sequence similarity 65, member ASource|GeneCards
KBTBD10KBTBD10kelch repeat and BTB (POZ) domain containing 10Source|GeneCards
IRS1IRS1insulin receptor substrate 1Source|GeneCards
CDW92CDW92CDW92 antigenSource|GeneCards
TTYH2TTYH2tweety homolog 2 (Drosophila)Source|GeneCards
CUTL1CUTL1cut-like 1, CCAAT displacement protein (Drosophila)Source|GeneCards
NRXN3NRXN3neurexin 3Source|GeneCards
LOC146174LOC146174hypothetical protein LOC146174Source|GeneCards
CASQ2CASQ2calsequestrin 2 (cardiac muscle)Source|GeneCards
ALS2CR2ALS2CR2amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2Source|GeneCards
LRRC20LRRC20leucine rich repeat containing 20Source|GeneCards
EEF1A2EEF1A2eukaryotic translation elongation factor 1 alpha 2Source|GeneCards
CKMCKMcreatine kinase, muscleSource|GeneCards
TIMP2TIMP2tissue inhibitor of metalloproteinase 2Source|GeneCards
TNNC2TNNC2troponin C2, fastSource|GeneCards
NEDD4NEDD4neural precursor cell expressed, developmentally down-regulated 4Source|GeneCards
PIK3R3PIK3R3phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)Source|GeneCards
CARTCARTcocaine- and amphetamine-regulated transcriptSource|GeneCards
KCNQ5KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5Source|GeneCards
TNNI3KTNNI3KTNNI3 interacting kinaseSource|GeneCards
PRKAG1PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunitSource|GeneCards
AMPD1AMPD1adenosine monophosphate deaminase 1 (isoform M)Source|GeneCards
S100A4S100A4S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)Source|GeneCards
ASB16ASB16ankyrin repeat and SOCS box-containing 16Source|GeneCards
ARP3BETAACTR3BARP3 actin-related protein 3 homolog B (yeast)Source|GeneCards
FLJ30058FLJ30058hypothetical protein FLJ30058Source|GeneCards
C6ORF162C6ORF162chromosome 6 open reading frame 162Source|GeneCards
BAI3BAI3brain-specific angiogenesis inhibitor 3Source|GeneCards
COL8A1COL8A1collagen, type VIII, alpha 1Source|GeneCards
HCFC1R1HCFC1R1host cell factor C1 regulator 1 (XPO1 dependant)Source|GeneCards
MYL2MYL2myosin, light polypeptide 2, regulatory, cardiac, slowSource|GeneCards
BNIP3BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3Source|GeneCards
BZW2BZW2basic leucine zipper and W2 domains 2Source|GeneCards
VIAATSLC32A1solute carrier family 32 (GABA vesicular transporter), member 1Source|GeneCards
NFAT5NFAT5nuclear factor of activated T-cells 5, tonicity-responsiveSource|GeneCards
POU4F1POU4F1POU domain, class 4, transcription factor 1Source|GeneCards
FLJ20184FLJ20184hypothetical protein FLJ20184Source|GeneCards
CAPN3CAPN3calpain 3, (p94)Source|GeneCards
GCKGCKglucokinase (hexokinase 4, maturity onset diabetes of the young 2)Source|GeneCards
TYRO3TYRO3TYRO3 protein tyrosine kinaseSource|GeneCards
MUSKMUSKmuscle, skeletal, receptor tyrosine kinaseSource|GeneCards
STAG2STAG2stromal antigen 2Source|GeneCards
MYL3MYL3myosin, light polypeptide 3, alkali; ventricular, skeletal, slowSource|GeneCards
ANKMY2ANKMY2ankyrin repeat and MYND domain containing 2Source|GeneCards
RALYRALYRNA binding protein (autoantigenic, hnRNP-associated with lethal yellow)Source|GeneCards
MGC14816LRRC39leucine rich repeat containing 39Source|GeneCards
MGC29643LYPD1LY6/PLAUR domain containing 1Source|GeneCards
MGC23947TCEAL7transcription elongation factor A (SII)-like 7Source|GeneCards
CRTAPCRTAPcartilage associated proteinSource|GeneCards
CACNA2D3CACNA2D3calcium channel, voltage-dependent, alpha 2/delta 3 subunitSource|GeneCards
TNFRSF17TNFRSF17tumor necrosis factor receptor superfamily, member 17Source|GeneCards
DIRAS1DIRAS1DIRAS family, GTP-binding RAS-like 1Source|GeneCards
SV2ASV2Asynaptic vesicle glycoprotein 2ASource|GeneCards
FILIP1FILIP1filamin A interacting protein 1Source|GeneCards
C10ORF71C10ORF71chromosome 10 open reading frame 71Source|GeneCards
POU4F2POU4F2POU domain, class 4, transcription factor 2Source|GeneCards
EHD1EHD1EH-domain containing 1Source|GeneCards
PCDH11YPCDH11Yprotocadherin 11 Y-linkedSource|GeneCards
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptideSource|GeneCards
KPNA3KPNA3karyopherin alpha 3 (importin alpha 4)Source|GeneCards
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2BSource|GeneCards
PCDH11XPCDH11Xprotocadherin 11 X-linkedSource|GeneCards
PEPP3PLEKHA6pleckstrin homology domain containing, family A member 6Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
RTBDNRTBDNretbindinSource|GeneCards
C9ORF126C9ORF126chromosome 9 open reading frame 126Source|GeneCards
FLJ12666C1ORF108chromosome 1 open reading frame 108Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
WFDC1WFDC1WAP four-disulfide core domain 1Source|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
WSB2WSB2WD repeat and SOCS box containing protein 2Source|GeneCards
CLCN1CLCN1chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)Source|GeneCards
MGC2655WDR58WD repeat domain 58Source|GeneCards
NDPNDPNorrie disease (pseudoglioma)Source|GeneCards
LOC81558LOC81558C/EBP-induced proteinSource|GeneCards
RASGRP3RASGRP3RAS guanyl releasing protein 3 (calcium and DAG-regulated)Source|GeneCards
USP2USP2ubiquitin specific protease 2Source|GeneCards
CFL2CFL2cofilin 2 (muscle)Source|GeneCards
MGC44287VSIG1V-set and immunoglobulin domain containing 1Source|GeneCards
TPP2TPP2tripeptidyl peptidase IISource|GeneCards
MRPS23MRPS23mitochondrial ribosomal protein S23Source|GeneCards
ATP2A3ATP2A3ATPase, Ca++ transporting, ubiquitousSource|GeneCards
CDC42EP3CDC42EP3CDC42 effector protein (Rho GTPase binding) 3Source|GeneCards
KLF14KLF14Kruppel-like factor 14Source|GeneCards
WBP4WBP4WW domain binding protein 4 (formin binding protein 21)Source|GeneCards
LCP1LCP1lymphocyte cytosolic protein 1 (L-plastin)Source|GeneCards
PCDH9PCDH9protocadherin 9Source|GeneCards
LIFLIFleukemia inhibitory factor (cholinergic differentiation factor)Source|GeneCards
SHANK1SHANK1SH3 and multiple ankyrin repeat domains 1Source|GeneCards
LUC7LLUC7LLUC7-like (S. cerevisiae)Source|GeneCards
HIST1H2BAHIST1H2BAhistone 1, H2baSource|GeneCards
HAKALPK2alpha-kinase 2Source|GeneCards
FSTFSTfollistatinSource|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
TNNI2TNNI2troponin I, skeletal, fastSource|GeneCards
PTPN1PTPN1protein tyrosine phosphatase, non-receptor type 1Source|GeneCards
ITSN1ITSN1intersectin 1 (SH3 domain protein)Source|GeneCards
KIAA1318RGAG1retrotransposon gag domain containing 1Source|GeneCards
MGST3MGST3microsomal glutathione S-transferase 3Source|GeneCards
HOXD4HOXD4homeo box D4Source|GeneCards
TRPS1TRPS1trichorhinophalangeal syndrome ISource|GeneCards
B3GTLB3GTLbeta 3-glycosyltransferase-likeSource|GeneCards
C18ORF25C18ORF25chromosome 18 open reading frame 25Source|GeneCards
USH3AUSH3AUsher syndrome 3ASource|GeneCards
MEF2CMEF2CMADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)Source|GeneCards
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1Source|GeneCards
ADAM11ADAM11a disintegrin and metalloproteinase domain 11Source|GeneCards
INPP4AINPP4Ainositol polyphosphate-4-phosphatase, type I, 107kDaSource|GeneCards
BRUNOL4BRUNOL4bruno-like 4, RNA binding protein (Drosophila)Source|GeneCards
CLDN23CLDN23claudin 23Source|GeneCards
GAL3ST3GAL3ST3Galactose-3-O-sulfotransferase 3Source|GeneCards
MBNL2MBNL2muscleblind-like 2 (Drosophila)Source|GeneCards
CTNND2CTNND2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)Source|GeneCards
RASGEF1BRASGEF1BRasGEF domain family, member 1BSource|GeneCards
PYY2PYY2peptide YY, 2 (seminalplasmin)Source|GeneCards
FLJ41841FLJ41841FLJ41841 proteinSource|GeneCards
TRDNTRDNtriadinSource|GeneCards
MAP2K5MAP2K5mitogen-activated protein kinase kinase 5Source|GeneCards
ATP1B2ATP1B2ATPase, Na+/K+ transporting, beta 2 polypeptideSource|GeneCards


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