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Gene set: V$RSRFC4_Q2 (C3:TFAC:0208)
Standard nameV$RSRFC4_Q2
Systematic nameC3:TFAC:0208
Brief descriptionGenes with 3'UTR containing motif ANKCTAWAAATAGMHNN which matches annotation for MEF2A: MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
XX
XX
FA RSRFC4
XX
SY RSRFC4.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia;
OC eutheria; primates
XX
XX
CL C0014; MADS; 4.4.1.1.1.3.
XX
SZ 497 AA; 53.6 kDa (cDNA)
XX
XX
SC conceptually translated from EMBL/GenBank/DDBJ #X63381
XX
FT 1 28 DNA binding specificity.
FT 1 105 DNA binding domain.
FT 1 59 PF00319; SRF-TF.
FT 1 60 SM00432; MADS.
FT 2 57 MADS box.
FT 87 130 replaced by 87-130 in RSRFC9.
XX
SF splice variants are MEF-2, aMEF-2, and RSRFC9 [2] [1];
SF no stable heterodimers with SRF [2];
XX
CP ubiquitous (adult) [1]
CN fetal skeletal muscle [1]
XX
FF although RSRFC4 binding sequences can act as promoter elements in
FF transfection assays, co-transfection with RSRFC4 does not lead to
FF additional transcriptional activation [2]
XX
IN T01785; MEF-2B-1; mouse, Mus musculus.
IN T01012; MEF-2B; human, Homo sapiens.
IN T01009; RSRFC4; human, Homo sapiens.
XX
XX
XX
XX
RN [1]; RE0000768.
RX MEDLINE; 92387551.
RA Yu Y.-T., Breitbart R. E., Smoot L. B., Lee Y., Mahdavi V., Nadal-Ginard B.
RT Human myocyte-specific enhancer factor 2 comprises a group of
RT tissue-restricted MADS box transcription factors
RL Genes Dev. 6:1783-1798 (1992).
RN [2]; RE0000769.
RX MEDLINE; 92084105.
RA Pollock R., Treisman R.
RT Human SRF-related proteins: DNA-binding properties and potential regulatory
RT targets
RL Genes Dev. 5:2327-2341 (1991).
XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

219 genes, 219 accessions (Toggle view)

AccessionGeneTitleLinks
ATF3ATF3activating transcription factor 3Source|GeneCards
ZNF533ZNF533Zinc finger protein 533Source|GeneCards
TM4SF13TSPAN13tetraspanin 13Source|GeneCards
FLJ90637C1ORF118chromosome 1 open reading frame 118Source|GeneCards
ARHGAP26ARHGAP26Rho GTPase activating protein 26Source|GeneCards
CYP2E1CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1Source|GeneCards
PAK6PAK6p21(CDKN1A)-activated kinase 6Source|GeneCards
PLAGL2PLAGL2pleiomorphic adenoma gene-like 2Source|GeneCards
FBXO40FBXO40F-box protein 40Source|GeneCards
LECT1LECT1leukocyte cell derived chemotaxin 1Source|GeneCards
GPC4GPC4glypican 4Source|GeneCards
SLCO2A1SLCO2A1solute carrier organic anion transporter family, member 2A1Source|GeneCards
HDAC7AHDAC7Ahistone deacetylase 7ASource|GeneCards
PDLIM1PDLIM1PDZ and LIM domain 1 (elfin)Source|GeneCards
SCA1ATXN1ataxin 1Source|GeneCards
DKK2DKK2dickkopf homolog 2 (Xenopus laevis)Source|GeneCards
ZHX2ZHX2transcription factor ZHX2Source|GeneCards
MGC45562MGC45562hypothetical protein MGC45562Source|GeneCards
ACTCACTCactin, alpha, cardiac muscleSource|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
RG9MTD2RG9MTD2RNA (guanine-9-) methyltransferase domain containing 2Source|GeneCards
FLJ32447FLJ32447hypothetical protein FLJ32447Source|GeneCards
HRMT1L3HRMT1L3HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae)Source|GeneCards
STOML2STOML2stomatin (EPB72)-like 2Source|GeneCards
SLC26A6SLC26A6solute carrier family 26, member 6Source|GeneCards
CPEB4CPEB4cytoplasmic polyadenylation element binding protein 4Source|GeneCards
MAB21L2MAB21L2mab-21-like 2 (C. elegans)Source|GeneCards
ITGB3BPITGB3BPintegrin beta 3 binding protein (beta3-endonexin)Source|GeneCards
ARHGEF15ARHGEF15Rho guanine nucleotide exchange factor (GEF) 15Source|GeneCards
FLJ45832FLJ45832FLJ45832 proteinSource|GeneCards
EYA1EYA1eyes absent homolog 1 (Drosophila)Source|GeneCards
ITGA7ITGA7integrin, alpha 7Source|GeneCards
DTNBDTNBdystrobrevin, betaSource|GeneCards
ZFPM2ZFPM2zinc finger protein, multitype 2Source|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
ESAMESAMendothelial cell adhesion moleculeSource|GeneCards
NR4A1NR4A1nuclear receptor subfamily 4, group A, member 1Source|GeneCards
RAB2RAB2RAB2, member RAS oncogene familySource|GeneCards
THBS2THBS2thrombospondin 2Source|GeneCards
KCNN1KCNN1potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1Source|GeneCards
LOC161247LOC161247similar to CG10671-likeSource|GeneCards
FBXW11FBXW11F-box and WD-40 domain protein 11Source|GeneCards
SLC8A3SLC8A3solute carrier family 8 (sodium-calcium exchanger), member 3Source|GeneCards
LYNLYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologSource|GeneCards
MYH4MYH4myosin, heavy polypeptide 4, skeletal muscleSource|GeneCards
RNF29TRIM55tripartite motif-containing 55Source|GeneCards
TMEPAITMEPAItransmembrane, prostate androgen induced RNASource|GeneCards
DGKIDGKIdiacylglycerol kinase, iotaSource|GeneCards
MYF6MYF6myogenic factor 6 (herculin)Source|GeneCards
SLCO3A1SLCO3A1solute carrier organic anion transporter family, member 3A1Source|GeneCards
SMARCA2SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2Source|GeneCards
ZNF216ZA20D2zinc finger, A20 domain containing 2Source|GeneCards
SCML1SCML1sex comb on midleg-like 1 (Drosophila)Source|GeneCards
RGS3RGS3regulator of G-protein signalling 3Source|GeneCards
EPHA7EPHA7EphA7Source|GeneCards
NR2F1NR2F1nuclear receptor subfamily 2, group F, member 1Source|GeneCards
TWIST1TWIST1twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)Source|GeneCards
FLJ31951FLJ31951hypothetical protein FLJ31951Source|GeneCards
STACSTACsrc homology three (SH3) and cysteine rich domainSource|GeneCards
ZNF143ZNF143zinc finger protein 143 (clone pHZ-1)Source|GeneCards
PTPROPTPROprotein tyrosine phosphatase, receptor type, OSource|GeneCards
POFUT1POFUT1protein O-fucosyltransferase 1Source|GeneCards
MEOX2MEOX2mesenchyme homeo box 2 (growth arrest-specific homeo box)Source|GeneCards
GPR153GPR153G protein-coupled receptor 153Source|GeneCards
PTCHPTCHpatched homolog (Drosophila)Source|GeneCards
KTN1KTN1kinectin 1 (kinesin receptor)Source|GeneCards
SSH3SSH3slingshot homolog 3 (Drosophila)Source|GeneCards
TGFB3TGFB3transforming growth factor, beta 3Source|GeneCards
ZNF161ZNF161zinc finger protein 161Source|GeneCards
CA7CA7carbonic anhydrase VIISource|GeneCards
BCL9LBCL9LB-cell CLL/lymphoma 9-likeSource|GeneCards
MYOZ2MYOZ2myozenin 2Source|GeneCards
TP73LTP73Ltumor protein p73-likeSource|GeneCards
HIBADHHIBADH3-hydroxyisobutyrate dehydrogenaseSource|GeneCards
MITFMITFmicrophthalmia-associated transcription factorSource|GeneCards
DNAJA4DNAJA4DnaJ (Hsp40) homolog, subfamily A, member 4Source|GeneCards
TPM2TPM2tropomyosin 2 (beta)Source|GeneCards
SMPXSMPXsmall muscle protein, X-linkedSource|GeneCards
ESR1ESR1estrogen receptor 1Source|GeneCards
SLAMF1SLAMF1signaling lymphocytic activation molecule family member 1Source|GeneCards
TNNC1TNNC1troponin C type 1 (slow)Source|GeneCards
PAX3PAX3paired box gene 3 (Waardenburg syndrome 1)Source|GeneCards
CUL3CUL3cullin 3Source|GeneCards
MIG12MID1IP1MID1 interacting protein 1 (gastrulation specific G12-like (zebrafish))Source|GeneCards
PRDM1PRDM1PR domain containing 1, with ZNF domainSource|GeneCards
HAPLN1HAPLN1hyaluronan and proteoglycan link protein 1Source|GeneCards
SOX5SOX5SRY (sex determining region Y)-box 5Source|GeneCards
FLJ20811ARMCX6armadillo repeat containing, X-linked 6Source|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
C21ORF29C21ORF29chromosome 21 open reading frame 29Source|GeneCards
HFE2HFE2Hemochromatosis type 2 (juvenile)Source|GeneCards
SLC26A9SLC26A9solute carrier family 26, member 9Source|GeneCards
CNTN1CNTN1contactin 1Source|GeneCards
TGFB1I4TSC22D1TSC22 domain family, member 1Source|GeneCards
EDG1EDG1endothelial differentiation, sphingolipid G-protein-coupled receptor, 1Source|GeneCards
RAP2CRAP2CRAP2C, member of RAS oncogene familySource|GeneCards
CSPG3CSPG3chondroitin sulfate proteoglycan 3 (neurocan)Source|GeneCards
HAO1HAO1hydroxyacid oxidase (glycolate oxidase) 1Source|GeneCards
FLJ33069TMEM71transmembrane protein 71Source|GeneCards
HAS2HAS2hyaluronan synthase 2Source|GeneCards
ALS2CR3ALS2CR3amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3Source|GeneCards
SLC2A4SLC2A4solute carrier family 2 (facilitated glucose transporter), member 4Source|GeneCards
DLG2DLG2Discs, large homolog 2, chapsyn-110 (Drosophila)Source|GeneCards
TCEA3TCEA3transcription elongation factor A (SII), 3Source|GeneCards
KBTBD5KBTBD5kelch repeat and BTB (POZ) domain containing 5Source|GeneCards
ART5ART5ADP-ribosyltransferase 5Source|GeneCards
CASQ1CASQ1calsequestrin 1 (fast-twitch, skeletal muscle)Source|GeneCards
ARR3ARR3arrestin 3, retinal (X-arrestin)Source|GeneCards
MGC35097MGC35097hypothetical protein MGC35097Source|GeneCards
SMYD1SMYD1SET and MYND domain containing 1Source|GeneCards
FGF12FGF12fibroblast growth factor 12Source|GeneCards
FLJ13725FAM65Afamily with sequence similarity 65, member ASource|GeneCards
KBTBD10KBTBD10kelch repeat and BTB (POZ) domain containing 10Source|GeneCards
IRS1IRS1insulin receptor substrate 1Source|GeneCards
TTYH2TTYH2tweety homolog 2 (Drosophila)Source|GeneCards
LOC146174LOC146174hypothetical protein LOC146174Source|GeneCards
CUTL1CUTL1cut-like 1, CCAAT displacement protein (Drosophila)Source|GeneCards
NRXN3NRXN3neurexin 3Source|GeneCards
KCNJ9KCNJ9potassium inwardly-rectifying channel, subfamily J, member 9Source|GeneCards
CASQ2CASQ2calsequestrin 2 (cardiac muscle)Source|GeneCards
ALS2CR2ALS2CR2amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2Source|GeneCards
ZCCHC5ZCCHC5zinc finger, CCHC domain containing 5Source|GeneCards
NME5NME5non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)Source|GeneCards
EEF1A2EEF1A2eukaryotic translation elongation factor 1 alpha 2Source|GeneCards
CKMCKMcreatine kinase, muscleSource|GeneCards
TNNC2TNNC2troponin C2, fastSource|GeneCards
NEDD4NEDD4neural precursor cell expressed, developmentally down-regulated 4Source|GeneCards
CARTCARTcocaine- and amphetamine-regulated transcriptSource|GeneCards
PIK3R3PIK3R3phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)Source|GeneCards
TNNI3KTNNI3KTNNI3 interacting kinaseSource|GeneCards
KCNQ5KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5Source|GeneCards
PRKAG1PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunitSource|GeneCards
AMPD1AMPD1adenosine monophosphate deaminase 1 (isoform M)Source|GeneCards
ASB16ASB16ankyrin repeat and SOCS box-containing 16Source|GeneCards
ARP3BETAACTR3BARP3 actin-related protein 3 homolog B (yeast)Source|GeneCards
TNNI1TNNI1troponin I, skeletal, slowSource|GeneCards
FLJ30058FLJ30058hypothetical protein FLJ30058Source|GeneCards
C6ORF162C6ORF162chromosome 6 open reading frame 162Source|GeneCards
BAI3BAI3brain-specific angiogenesis inhibitor 3Source|GeneCards
COL8A1COL8A1collagen, type VIII, alpha 1Source|GeneCards
BZW2BZW2basic leucine zipper and W2 domains 2Source|GeneCards
MYL2MYL2myosin, light polypeptide 2, regulatory, cardiac, slowSource|GeneCards
BNIP3BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3Source|GeneCards
VIAATSLC32A1solute carrier family 32 (GABA vesicular transporter), member 1Source|GeneCards
NFAT5NFAT5nuclear factor of activated T-cells 5, tonicity-responsiveSource|GeneCards
POU4F1POU4F1POU domain, class 4, transcription factor 1Source|GeneCards
MYL1MYL1myosin, light polypeptide 1, alkali; skeletal, fastSource|GeneCards
C7ORF20C7ORF20chromosome 7 open reading frame 20Source|GeneCards
FLJ20184FLJ20184hypothetical protein FLJ20184Source|GeneCards
TAF5LTAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDaSource|GeneCards
CAPN3CAPN3calpain 3, (p94)Source|GeneCards
TYRO3TYRO3TYRO3 protein tyrosine kinaseSource|GeneCards
MUSKMUSKmuscle, skeletal, receptor tyrosine kinaseSource|GeneCards
MYL3MYL3myosin, light polypeptide 3, alkali; ventricular, skeletal, slowSource|GeneCards
ANKMY2ANKMY2ankyrin repeat and MYND domain containing 2Source|GeneCards
RALYRALYRNA binding protein (autoantigenic, hnRNP-associated with lethal yellow)Source|GeneCards
CRTAPCRTAPcartilage associated proteinSource|GeneCards
CACNA2D3CACNA2D3calcium channel, voltage-dependent, alpha 2/delta 3 subunitSource|GeneCards
TNFRSF17TNFRSF17tumor necrosis factor receptor superfamily, member 17Source|GeneCards
DIRAS1DIRAS1DIRAS family, GTP-binding RAS-like 1Source|GeneCards
JMJD1CJMJD1Cjumonji domain containing 1CSource|GeneCards
SLC29A2SLC29A2solute carrier family 29 (nucleoside transporters), member 2Source|GeneCards
SV2ASV2Asynaptic vesicle glycoprotein 2ASource|GeneCards
FILIP1FILIP1filamin A interacting protein 1Source|GeneCards
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptideSource|GeneCards
KPNA3KPNA3karyopherin alpha 3 (importin alpha 4)Source|GeneCards
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2BSource|GeneCards
PEPP3PLEKHA6pleckstrin homology domain containing, family A member 6Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
C9ORF126C9ORF126chromosome 9 open reading frame 126Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
WFDC1WFDC1WAP four-disulfide core domain 1Source|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
CLCN1CLCN1chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)Source|GeneCards
NDPNDPNorrie disease (pseudoglioma)Source|GeneCards
SSPNSSPNsarcospan (Kras oncogene-associated gene)Source|GeneCards
LOC81558LOC81558C/EBP-induced proteinSource|GeneCards
RASGRP3RASGRP3RAS guanyl releasing protein 3 (calcium and DAG-regulated)Source|GeneCards
USP2USP2ubiquitin specific protease 2Source|GeneCards
MGC44287VSIG1V-set and immunoglobulin domain containing 1Source|GeneCards
TPP2TPP2tripeptidyl peptidase IISource|GeneCards
MRPS23MRPS23mitochondrial ribosomal protein S23Source|GeneCards
ATP2A3ATP2A3ATPase, Ca++ transporting, ubiquitousSource|GeneCards
SLC30A1SLC30A1solute carrier family 30 (zinc transporter), member 1Source|GeneCards
CDC42EP3CDC42EP3CDC42 effector protein (Rho GTPase binding) 3Source|GeneCards
FLJ41603FLJ41603FLJ41603 proteinSource|GeneCards
WBP4WBP4WW domain binding protein 4 (formin binding protein 21)Source|GeneCards
KLF14KLF14Kruppel-like factor 14Source|GeneCards
PCDH9PCDH9protocadherin 9Source|GeneCards
LIFLIFleukemia inhibitory factor (cholinergic differentiation factor)Source|GeneCards
GABRB2GABRB2gamma-aminobutyric acid (GABA) A receptor, beta 2Source|GeneCards
LUC7LLUC7LLUC7-like (S. cerevisiae)Source|GeneCards
TRIM33TRIM33tripartite motif-containing 33Source|GeneCards
FLJ44968FLJ44968FLJ44968 proteinSource|GeneCards
PCBP2PCBP2poly(rC) binding protein 2Source|GeneCards
PTPN1PTPN1protein tyrosine phosphatase, non-receptor type 1Source|GeneCards
KIAA1318RGAG1retrotransposon gag domain containing 1Source|GeneCards
MGST3MGST3microsomal glutathione S-transferase 3Source|GeneCards
HOXD4HOXD4homeo box D4Source|GeneCards
TRPS1TRPS1trichorhinophalangeal syndrome ISource|GeneCards
B3GTLB3GTLbeta 3-glycosyltransferase-likeSource|GeneCards
USH3AUSH3AUsher syndrome 3ASource|GeneCards
BNC2BNC2basonuclin 2Source|GeneCards
INPP4AINPP4Ainositol polyphosphate-4-phosphatase, type I, 107kDaSource|GeneCards
ADAM11ADAM11a disintegrin and metalloproteinase domain 11Source|GeneCards
BRUNOL4BRUNOL4bruno-like 4, RNA binding protein (Drosophila)Source|GeneCards
FLJ33207KYkyphoscoliosis peptidaseSource|GeneCards
ASPHASPHaspartate beta-hydroxylaseSource|GeneCards
MBNL2MBNL2muscleblind-like 2 (Drosophila)Source|GeneCards
LOC221143LOC221143hypothetical protein LOC221143Source|GeneCards
CTNND2CTNND2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)Source|GeneCards
RASGEF1BRASGEF1BRasGEF domain family, member 1BSource|GeneCards
PYY2PYY2peptide YY, 2 (seminalplasmin)Source|GeneCards
SDHCSDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDaSource|GeneCards
FLJ41841FLJ41841FLJ41841 proteinSource|GeneCards
TRDNTRDNtriadinSource|GeneCards
MAP2K5MAP2K5mitogen-activated protein kinase kinase 5Source|GeneCards
HS3ST5HS3ST5heparan sulfate (glucosamine) 3-O-sulfotransferase 5Source|GeneCards
ATP1B2ATP1B2ATPase, Na+/K+ transporting, beta 2 polypeptideSource|GeneCards


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