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Gene set: V$SP1_Q6 (C3:TFAC:0127)
Standard nameV$SP1_Q6
Systematic nameC3:TFAC:0127
Brief descriptionGenes with 3'UTR containing motif NGGGGGCGGGGYN which matches annotation for SP1: Sp1 transcription factor
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA Sp1
 XX
 SY Sp1; simian-virus-40-protein-1.

XX
 OS human, Homo sapiens
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0001; CH; 2.3.1.0.2.
 XX
 SZ >696 AA;
105+95 kDa (SDS)
 XX
 XX
 SC translated from EMBL #J03133

XX
 FT 57 162 Q-rich region (23/106), domain A [52], necessary
for
 FT synergistic activation [4].
 FT 67 124 PS50322;
GLN_RICH_1.
 FT 263 405 Q-rich region (39/143), domain B, important
for
 FT multimerization [52].
 FT 263 391 PS50322; GLN_RICH_2.

FT 304 485 important for direct interaction with Oct-1 [3].

FT 471 537 charged region, domain C [52]; essential for synergistic
DNA
 FT binding along with SREBP-1 [4].
 FT 537 561 PF00096;
zf-C2H2.
 FT 537 561 SM00355; ZnF_C2H2.
 FT 539 561 zinc
finger 1.
 FT 539 696 interaction with YY1 [9].
 FT 567
591 PF00096; zf-C2H2.
 FT 567 591 SM00355; ZnF_C2H2.
 FT
569 591 zinc finger 2.
 FT 597 619 SM00355; ZnF_C2H2.
 FT
597 619 PF00096; zf-C2H2.
 FT 599 619 zinc finger 3.
 FT
620 696 domain D, required for synergism [20] [4].
 XX

SF Q-rich activation domain may mediate self-aggregation [7];

SF S/T-rich stretch [6];
 SF base contacts arise from the second
and the third zinc fingers [10];
 SF Zn2+ can be substituted
for Cd2+, Co2+, less favourable: Mn2+, Ni2+;
 SF thionein inhibits
DNA-binding;
 SF Kd 0.41-0.53 nM;
 SF t1/2 for binding to
and dissociation from DNA < 1 min;
 SF phosphorylation (DNA-dependent
protein kinase);
 SF homology to factors SP3  and SP4
 [12];
 SF possibly glycosylated [8];
 SF interacts
with NF-kappaB by its trans-acting domain when bound to an

SF adjacent site [6];
 SF interacts secies-specifically with
human, but not with Drosophila TFIID
 SF complex [2];
 XX

CP (HeLa); ubiquitous [14]
 XX
 FF multimerization leads
to superactivation;
 FF effect of Sp1-sites depends on distance
to TATA-box [22];
 FF synergistically cooperates with E2 at
BPV promoters [17];
 FF highly specific cooperation with NF-kappaB
[6];
 FF binding inhibited by formation of triple-stranded
structures [13];
 FF binds to its site even when reconstituted
into nucleosome cores [7];
 FF affinity for nucleosomal DNA
is reduced relative to naked DNA [7];
 XX
 IN T00205; E2;
BPV-1, bovine papilloma virus type 1.
 IN T00590; NF-kappaB;
human, Homo sapiens.
 IN T02375; NS-1; MVM(p), minute virus
of mice.
 IN T01486; p107; human, Homo sapiens.
 IN T00759;
Sp1; human, Homo sapiens.
 IN T02121; TAF(II)110; fruit fly,
Drosophila melanogaster.
 IN T02328; TAF(II)135; human, Homo
sapiens.
 IN T00782; TAF(II)55; human, Homo sapiens.
 IN
T00794; TBP; human, Homo sapiens.
 IN T00795; TBP; fission
yeast, Schizosaccharomyces pombe.
 IN T00796; TBP; mouse, Mus
musculus.
 IN T00797; TBP; fruit fly, Drosophila melanogaster.

IN T00798; TBP; yeast, Saccharomyces cerevisiae.
 IN T02399;
Vpr; HIV-1, human immunodeficiency virus type 1.
 IN T00915;
YY1; human, Homo sapiens.
 XX
 XX
 XX
 XX
 RN [1];
RE0006859.
 RX MEDLINE; 98108022.
 RA Emami K. H., Burke
T. W., Smale S. T.
 RT Sp1 activation of a TATA-less promoter
requires a species-specific
 RT interaction involving transcription
factor IID
 RL Nucleic Acids Res. 26:839-846 (1998).
 RN
[2]; RE0006858.
 RX MEDLINE; 98088918.
 RA Ton-That H.,
Kaestner K. H., Shields J. M., Mahatanankoon C. S., Yang V. W.

RT Expression of the gut-enriched Krueppel-like factor gene during
development
 RT and intestinal tumorigenesis
 RL FEBS Lett.
419:239-243 (1997).
 RN [3]; RE0006546.
 RX MEDLINE; 96251075.

RA Stroem A.-C., Forsberg M., Lillhager P., Westin G.
 RT The
transcription factors Sp1 and Oct-1 interact physically to regulate

RT human U2 snRNA gene expression
 RL Nucleic Acids Res. 24:1981-1986
(1996).
 RN [4]; RE0006739.
 RX MEDLINE; 95320223.
 RA
Yieh L., Sanchez H. B., Osborne T. F.
 RT Domains of transcription
factor Sp1 required for synergistic activation
 RT with sterol
regulatory element binding protein 1 of low density lipoprotein

RT receptor promoter
 RL Proc. Natl. Acad. Sci. USA 92:6102-6106
(1995).
 RN [5]; RE0001710.
 RX MEDLINE; 94158831.
 RA
Emili A., Greenblatt J., Ingles C. J.
 RT Species-specific
interaction of the glutamine-rich acitvation domains of
 RT
Sp1 with the TATA box-binding protein
 RL Mol. Cell. Biol.
14:1582-1593 (1994).
 RN [6]; RE0006654.
 RX MEDLINE; 95098605.

RA Majello B., de Luca P., Hagen G., Suske G., Lania L.
 RT
Different members of the Sp1 multigene family exert opposite

RT transcriptional regulation of the long terminal repeat of HIV-1

RL Nucleic Acids Res. 22:4914-4921 (1994).
 RN [7]; RE0006663.

RX MEDLINE; 94171813.
 RA Li B., Adams C. C., Workman J. L.

RT Nucleosome binding by the constitutive transcription factor
Sp1
 RL J. Biol. Chem. 269:7756-7763 (1994).
 RN [8]; RE0006574.

RX MEDLINE; 93314966.
 RA Geiser A. G., Busam K. J., Kim S.-J.,
Lafyatis R., O'Reilly M. A., Webbink
 RA R., Roberts A. B.,
Sporn M. B.
 RT Regulation of the transforming growth factor-beta1
and -beta3 promoters by
 RT transcription factor Sp1
 RL
Gene 129:223-228 (1993).
 RN [9]; RE0006591.
 RX MEDLINE;
93317640.
 RA Lee J.-S., Galvin K. M., Shi Y.
 RT Evidence
for physical interaction between the zinc-finger transcription

RT factors YY1 and Sp1
 RL Proc. Natl. Acad. Sci. USA 90:6145-6149
(1993).
 RN [10]; RE0006637.
 RX MEDLINE; 93356835.

RA Nagaoka M., Kuwahara J., Sugiura Y.
 RT Alteration of DNA
binding specificity by nickel (II) substitution in three
 RT
zinc (II) fingers of transcription factor Sp1.
 RL Biochem.
Biophys. Res. Commun. 194:1515-1520 (1993).
 RN [11]; RE0002242.

RX MEDLINE; 92366166.
 RA Chen X., Azizkhan J. C., Lee D. C.

RT The binding of transcription factor SP1 to multiple sites is
required for
 RT maximal expression from the rat transforming
growth factor alpha promoter
 RL Oncogene 7:1805-1815 (1992).

RN [12]; RE0006538.
 RX MEDLINE; 93087156.
 RA Hagen G.,
Muller S., Beato M., Suske G.
 RT Cloning by recognition site
screening of two novel GT box binding proteins:
 RT a familiy
of Sp1 related genes
 RL Nucleic Acids Res. 20:5519-5525 (1992).

RN [13]; RE0006549.
 RX MEDLINE; 92283818.
 RA Gee J. E.,
Blume S., Snyder R. C., Ray R., Miller D. M.
 RT Triplex formation
prevents Sp1 binding to the dihydrofolate resuctase
 RT promoter

RL J. Biol. Chem. 267:11163-11167 (1992).
 RN [14]; RE0006565.

RX MEDLINE; 92307657.
 RA Avraham K. B., Prezioso V. R., Chen
W. S., Lai E., Sladek F. M., Zhong W.,
 RA Darnell jr J. E.,
Jenkins N. A., Copeland N. G.
 RT Murine Chromosomal Location
of Four Hepatocyte-Enriched Transcription
 RT Factors: HNF-3alpha,
HNF-3beta, HNF-3gamma, and HNF-4
 RL Genomics 13:264-268 (1992).

RN [15]; RE0000010.
 RX MEDLINE; 91151370.
 RA Thiesen H.-J.,
Schroeder B.
 RT Amino acid substitutions in the Sp1 zinc finger
domain alter the DNA
 RT binding affinity to cognate Sp1 target
site
 RL Biochem. Biophys. Res. Commun. 175:333-338 (1991).

RN [16]; RE0000011.
 RX MEDLINE; 91222214.
 RA Thiesen H.-J.,
Bach C.
 RT Transition metals modulate DNA-protein interactions
of Sp1 zinc finger
 RT domains with its cognate target site

RL Biochem. Biophys. Res. Commun. 176:551-557 (1991).
 RN [17];
RE0000237.
 RX MEDLINE; 91208686.
 RA Li R., Knight J. D.,
Jackson S. P., Tijan R., Botchan M. R.
 RT Direct interaction
between Sp1 and the BPV Enhancer E2 protein mediates
 RT synergistic
activation of transcription
 RL Cell 65:493-505 (1991).

RN [18]; RE0000581.
 RX MEDLINE; 91160740.
 RA Zeng J.,
Heuchel R., Schaffner W., Kaegi J. H. R.
 RT Thionein (apometallothionein)
can modulate DNA binding and transcription
 RT activation by
zinc finger containing factor Sp1
 RL FEBS Lett. 279:310-312
(1991).
 RN [19]; RE0000693.
 RX MEDLINE; 91224491.

RA Su W., Jackson S., Tjian R., Echols H.
 RT DNA looping between
site for transcriptional activation: self-association
 RT of
DNA-bound Sp1
 RL Genes Dev. 5:820-826 (1991).
 RN [20];
RE0000707.
 RX MEDLINE; 91357479.
 RA Pascal E., Tjian R.

RT Different activation domains of Sp1 govern formation of multimers
and
 RT mediate transcriptional synergism
 RL Genes Dev.
5:1646-1656 (1991).
 RN [21]; RE0000708.
 RX MEDLINE; 91224491.

RA Su W., Jackson S., Tjian R., Echols H.
 RT DNA looping between
site for transcriptional activation: self-association
 RT of
DNA-bound Sp1
 RL Genes Dev. 5:820-826 (1991).
 RN [22];
RE0000929.
 RX MEDLINE; 92041874.
 RA Segal R., Berk A.
J.
 RT Promoter activity and distance constraints of one versus
two Sp1 binding
 RT sites
 RL J. Biol. Chem. 266:20406-20411
(1991).
 RN [23]; RE0001001.
 RX MEDLINE; 91250433.

RA Kagawa N., Waterman M. R.
 RT Evidence that an adrenal-specific
nuclear protein regulates the cAMP
 RT responsiveness of the
human CYP21B (P450C21) gene
 RL J. Biol. Chem. 266:11199-11204
(1991).
 RN [24]; RE0001013.
 RX MEDLINE; 91139695.

RA Araki E., Murakami T., Shirotani T., Kanai F., Shinohara Y.,
Shimada F.,
 RA Mori M., Shichiri M., Ebina Y.
 RT A cluster
of four Sp1 binding sites required for efficient expression of

RT the human insulin receptor gene
 RL J. Biol. Chem. 266:3944-3948
(1991).
 RN [25]; RE0001022.
 RX MEDLINE; 91224987.

RA Yu C.-Y., Motamed K., Chen J., Bailey A. D., Shen C.-K. J.

RT The CACC box upstream of human embryonic epsilon globin gene
binds Sp1 and
 RT is a functional promoter element in vitro
and in vivo
 RL J. Biol. Chem. 266:8907-8915 (1991).
 RN
[26]; RE0001495.
 RX MEDLINE; 91172208.
 RA Saffer J. D.,
Jackson S. P., Annarella M. B.
 RT Developmental expression
of Sp1 in the mouse
 RL Mol. Cell. Biol. 11:2189-2199 (1991).

RN [27]; RE0001611.
 RX MEDLINE; 91172211.
 RA Spanopoulou
E., Giguere V., Grosveld F.
 RT The functional domains of the
murine Thy-1 gene promoter
 RL Mol. Cell. Biol. 11:2216-2228
(1991).
 RN [28]; RE0001615.
 RX MEDLINE; 91172179.

RA Anderson G. M., Freytag S. O.
 RT Synergistic activation
of a human promoter in vivo by transcription factor
 RT Sp1

RL Mol. Cell. Biol. 11:1935-1943 (1991).
 RN [29]; RE0001890.

RX MEDLINE; 91095025.
 RA Nardelli J., Gibson T. J., Vesque
C., Charnay P.
 RT Base sequence discrimination by zinc-finger
DNA-binding domains
 RL Nature 349:175-178 (1991).
 RN [30];
RE0002428.
 RX MEDLINE; 91288526.
 RA Mastrangelo I. A.,
Courey A. J., Wall J. S., Jackson S. P., Hough P. V. C.
 RT
DNA looping and Sp1 multimer links: a mechanism for transcriptional

RT synergism and enhancement
 RL Proc. Natl. Acad. Sci. USA
88:5670-5674 (1991).
 RN [31]; RE0002466.
 RX MEDLINE; 91142131.

RA Dou Q.-P., Fridovich-Keil J. L., Pardee A. B.
 RT Inducible
proteins binding to the murine thymidine kinase promoter in late

RT G1/S phase
 RL Proc. Natl. Acad. Sci. USA 88:1157-1161 (1991).

RN [32]; RE0000182.
 RX MEDLINE; 91004214.
 RA Jackson S.
P., MacDonald J. J., Lees-Miller S., Tjian R.
 RT GC box binding
induces phosphorylation by a DNA-dependent protein kinase

RL Cell 63:155-165 (1990).
 RN [33]; RE0000197.
 RX MEDLINE;
91004214.
 RA Jackson S. P., MacDonald J. J., Lees-Miller S.,
Tjian R.
 RT GC box binding induces phosphorylation by a DNA-dependent
protein kinase
 RL Cell 63:155-165 (1990).
 RN [34]; RE0000691.

RX MEDLINE; 91065526.
 RA Sartorelli V., Webster K. A., Kedes
L.
 RT Muscle-specific expression of the cardiac alpha-actin
gene requires MyoD1,
 RT CArG-box binding factor, and Sp1

RL Genes Dev. 4:1811-1822 (1990).
 RN [35]; RE0000692.

RX MEDLINE; 90299136.
 RA Saffer J. D., Jackson S. P., Thurston
S. J.
 RT SV40 stimulates expression of the trans-acting factor
Sp1 at the mRNA level
 RL Genes Dev. 4:659-666 (1990).

RN [36]; RE0000988.
 RX MEDLINE; 91056103.
 RA Boyer T.
G., Maquat L. E.
 RT Minimal sequence and factor requirements
for the initiation of
 RT transcription from an atypical, TATATAA
box-containing housekeeping promoter
 RL J. Biol. Chem. 265:20524-20532
(1990).
 RN [37]; RE0001271.
 RX MEDLINE; 90205866.

RA Lemaigre F. P., Lafontaine D. A., Courtois S. J., Durviaux
S. M., Rousseau
 RA G. G.
 RT Sp1 can displace GHF-1 from
its distal binding site and stimulate
 RT transcription from
the growth hormone gene promoter
 RL Mol. Cell. Biol. 10:1811-1814
(1990).
 RN [38]; RE0001437.
 RX MEDLINE; 90097868.

RA Sykes K., Kaufman R.
 RT A Naturally Occurring Gamma Globin
Gene Mutation Enhances SP1 Binding
 RT Activity
 RL Mol.
Cell. Biol. 10:95-102 (1990).
 RN [39]; RE0002113.
 RX MEDLINE;
90287694.
 RA Thiesen H.-J., Bach C.
 RT Target detection
assay (TDA): a versatile procedure to determine DNA
 RT binding
sites as demonstrated on SP1 protein
 RL Nucleic Acids Res.
18:3202-3209 (1990).
 RN [40]; RE0000196.
 RX MEDLINE; 90075227.

RA Courey A. J., Holtzman D. A., Jackson S. P., Tjian R.
 RT
Synergistic activation by the glutamine-rich domains of human
transcription
 RT factor Sp1
 RL Cell 59:827-836 (1989).

RN [41]; RE0000883.
 RX MEDLINE; 90037078.
 RA Kim S.-J.,
Denhez F., Kim K. Y., Holt J. T., Sporn M. B., Roberts A. B.

RT Activation of the Second Promoter of the Transforming Growth
Factor-beta1
 RT Gene by Transforming Growth Factor-beta1 and
Phorbol Ester Occurs through
 RT the Same Target Sequences

RL J. Biol. Chem. 264:19373-19378 (1989).
 RN [42]; RE0000899.

RX MEDLINE; 89340553.
 RA Evans M. J., Scarpulla R. C.

RT Interaction of Nuclear Factors with Multiple Sites in the Somatic

RT Cytochrome c Promoter
 RL J. Biol. Chem. 264:14361-14368
(1989).
 RN [43]; RE0001025.
 RX MEDLINE; 89278150.

RA Miralles V. J., Cortes P., Stone N., Reinberg D.
 RT The
adenovirus inverted terminal repeat functions as an enhancer in
a
 RT cell-free system
 RL J. Biol. Chem. 264:10763-10772
(1989).
 RN [44]; RE0001374.
 RX MEDLINE; 90014780.

RA Gustafson T. A., Kedes L.
 RT Identification of Multiple
Proteins That Interact with Functional Regions
 RT of the Human
Cardiac alpha-Actin Promoter
 RL Mol. Cell. Biol. 9:3269-3283
(1989).
 RN [45]; RE0001375.
 RX MEDLINE; 90014783.

RA Schmidt M. C., Zhou Q., Berk A. J.
 RT Sp1 Activates Transcription
without Enhancing DNA-Binding Activity of the
 RT TATA Box
Factor
 RL Mol. Cell. Biol. 9:3299-3307 (1989).
 RN [46];
RE0001383.
 RX MEDLINE; 89384647.
 RA Morgan W. D.
 RT
Transcriptional Factor Sp1 Binds to and Activates a Human hsp70
Gene
 RT Promoter
 RL Mol. Cell. Biol. 9:4099-4104 (1989).

RN [47]; RE0002041.
 RX MEDLINE; 89240024.
 RA Letovsky
J., Dynan W. S.
 RT Measurement of the binding of transcription
factor Sp1 to a single GC box
 RT recognition sequence

RL Nucleic Acids Res. 17:2639-2653 (1989).
 RN [48]; RE0002053.

RX MEDLINE; 90067825.
 RA Hughes M. J., Jost J.-P.
 RT The
ubiquitous nuclear protein, NHP1, binds with high affinity to
different
 RT sequences of the chicken vitellogenin II gene

RL Nucleic Acids Res. 17:8511-8520 (1989).
 RN [49]; RE0002066.

RX MEDLINE; 90098860.
 RA Ben-Hattar J., Beard P., Jiricny
J.
 RT Cytosine methylation in CTF and Sp1 recognition sites
of an HSV tk
 RT promoter: effects on transcription in vivo
and on factor binding in vitro
 RL Nucleic Acids Res. 17:10179-10190
(1989).
 RN [50]; RE0002067.
 RX MEDLINE; 90098865.

RA Ronchi A., Nicolis S., Santoro C., Ottolenghi S.
 RT Increased
Sp1 binding mediates erythroid-specific overexpression of a

RT mutated (HPFH) gamma-globulin promoter
 RL Nucleic Acids
Res. 17:10231-10241 (1989).
 RN [51]; RE0000101.
 RX MEDLINE;
89051877.
 RA Angel P., Hattori K., Smeal T., Karin M.

RT The jun proto-oncogene is positively autoregulated by its product,
Jun/AP-1
 RL Cell 55:875-885 (1988).
 RN [52]; RE0000121.

RX MEDLINE; 89051878.
 RA Courey A. J., Tjian R.
 RT Analysis
of Sp1 in vivo reveals multiple transcriptional domains, including

RT a novel glutamine-rich activation motif
 RL Cell 55:887-898
(1988).
 RN [53]; RE0000380.
 RX MEDLINE; 89091123.

RA Westin G., Schaffner W.
 RT A zinc-responsive factor interacts
with a metal-regulated enhancer element
 RT (MRE) of the mouse
metallothionein-I gene
 RL EMBO J. 7:3763-3770 (1988).

RN [54]; RE0000817.
 RX MEDLINE; 88228059.
 RA Smith J.
D., Melian A., Leff T., Breslow J. L.
 RT Expression of the
Human Apolipoprotein E Gene is Regulated by Multiple
 RT Positive
and Negative Elements
 RL J. Biol. Chem. 263:8300-8308 (1988).

RN [55]; RE0000818.
 RX MEDLINE; 88330840.
 RA Paik Y.-K.,
Chang D. J., Reardon C. A., Walker M. D., Taxman E., Taylor J.

RA M.
 RT Identification and Characterization of Transcriptional
Regulatory Regions
 RT Associated with Expression of the Human
Apolipoprotein E Gene
 RL J. Biol. Chem. 263:13340-13349 (1988).

RN [56]; RE0001242.
 RX MEDLINE; 89039842.
 RA Johnson A.
C., Jinno Y., Merlino G. T.
 RT Modulation of Epidermal Growth
Factor Receptor Proto-Oncogene Transcription
 RT by a promoter
Site Sensitive to S1 Nuclease
 RL Mol. Cell. Biol. 8:4174-4184
(1988).
 RN [57]; RE0001953.
 RX MEDLINE; 88335604.

RA Dush M. K., Briggs M. R., Royce M. E., Schaff D. A., Khan S.
A., Tischfeld
 RA J. A., Stambrook P. J.
 RT Identification
of DNA sequences required for mouse APRT gene expression
 RL
Nucleic Acids Res. 16:8509-8524 (1988).
 RN [58]; RE0002025.

RX MEDLINE; 88289333.
 RA Westin G., Schaffner W.
 RT Heavy
metal ions in transcription factors from HeLa cells: Sp1, but
not
 RT octamer transcription factor requires zinc for DNA
binding and for
 RT activator functions
 RL Nucleic Acids
Res. 16:5771-5781 (1988).
 RN [59]; RE0002324.
 RX MEDLINE;
88176887.
 RA Harrington M., Jones P. A., Imagawa M., Karin
M.
 RT Cytosine methylation does not affect binding of transcription
factor Sp1
 RL Proc. Natl. Acad. Sci. USA 85:2066-2070 (1988).

RN [60]; RE0000105.
 RX MEDLINE; 87301729.
 RA Mitchell
P., Wang C., Tjian R.
 RT Positive and Negative Regulation
of Transcription In Vitro:
 RT Enhancer-Binding Protein AP-2
Is Inhibited by SV40 T Antigen
 RL Cell 50:847-861 (1987).

RN [61]; RE0000138.
 RX MEDLINE; 88080466.
 RA Kadonaga
J. T., Carner K. R., Masiarz F. R., Tjian R.
 RT Isolation
of cDNA encoding transcription factor Sp1 and functional analysis

RT of the DNA binding domain
 RL Cell 51:1079-1090 (1987).

RN [62]; RE0000354.
 RX MEDLINE; 88111565.
 RA Garcia J.
A., Wu F. K., Mitsuyasu R., Gaynor R. B.
 RT Interaction of
cellular proteins involved in the transcriptional regulation

RT of the human immunodeficiency virus
 RL EMBO J. 6:3761-3770
(1987).
 RN [63]; RE0001283.
 RX MEDLINE; 88065503.

RA Greene J. M., Larin Z., Taylor I. C. A., Prentice H., Gwinn
K. A., Kingston
 RA R. E.
 RT Multiple Basal Elements of
a Human hsp70 Promoter Function Differently in
 RT Human and
Rodent Cell Lines
 RL Mol. Cell. Biol. 7:3646-3655 (1987).

RN [64]; RE0001813.
 RX MEDLINE; 87115798.
 RA Lee W., Haslinger
A., Karin M., Tjian R.
 RT Activation of transcription by two
factors that bind promoter and enhancer
 RT sequences of the
human metallothionein gene and SV40
 RL Nature 325:368-372
(1987).
 RN [65]; RE0002028.
 RX MEDLINE; 87259982.

RA Janson L., Bark C., Petterson U.
 RT Identification of proteins
interacting with the enhancer of human U2 small
 RT nuclear
RNA genes
 RL Nucleic Acids Res. 15:4997-5016 (1987).
 RN
[66]; RE0001774.
 RX MEDLINE; 86118666.
 RA Dynan W. S.,
Sazer S., Tjian R., Schimke R. T.
 RT Transcription factor
Sp1 recognizes a DNA sequence in the mouse
 RT dihydrofolate
reductase promoter
 RL Nature 319:246-248 (1986).
 RN [67];
RE0002361.
 RX MEDLINE; 86205850.
 RA Das G. C., Piatigorsky
J.
 RT The chicken delta1-crystallin gene promoter: binding
of transcription
 RT factor(s) to the upstream G+C-rich region
is necessary for promoter
 RT function invitro
 RL Proc.
Natl. Acad. Sci. USA 83:3131-3135 (1986).
 RN [68]; RE0002606.

RX MEDLINE; 86179897.
 RA Jones K. A., Kadonaga J. T., Luciw
P. A., Tjian R.
 RT Activation of the AIDS retrovirus promoter
by the cellular transcription
 RT factor, Sp1
 RL Science
232:755-759 (1986).
 RN [69]; RE0002626.
 RX MEDLINE; 86235432.

RA Ishii S., Kadonaga J. T., Tjian R., Brady J. N., Merlin G.
T., Pastan I.
 RT Binding of the Sp1 Transcription Factor by
the Human Harvey ras1
 RT Proto-oncogene Promoter
 RL Science
232:1410-1413 (1986).
 RN [70]; RE0000126.
 RX MEDLINE;
85282613.
 RA Jones K. A., Yamamoto K. R., Tjian R.
 RT
Two distinct transcription factors that bind to the HSV thymidine
kinase
 RT promoter in vitro
 RL Cell 42:559-572 (1985).

RN [71]; RE0001798.
 RX MEDLINE; 85296380.
 RA Jones K.
A., Tjian R.
 RT Sp1 binds to promoter sequences and activates
herpes simplex virus
 RT 'immediate-early' gene transcription
in vitro
 RL Nature 317:179-182 (1985).
 RN [72]; RE0002349.

RX MEDLINE; 85270437.
 RA Dynan W. S., Safer J. D., Lee W.
S., Tjian R.
 RT Transcription factor Sp1 recognizes promoter
sequences from the monkey
 RT genome that are similiar to the
simian virus 40 promoter
 RL Proc. Natl. Acad. Sci. USA 82:4915-4919
(1985).
 RN [73]; RE0002628.
 RX MEDLINE; 86018849.

RA Gidoni D., Kadonaga J. T., Barrera-Saldana H., Takahashi K.,
Chambon P.,
 RA Tjian R.
 RT Bidirectional SV40 transcription
mediated by tandem Sp1 binding interactions
 RL Science 230:511-517
(1985).
 RN [74]; RE0001823.
 RX MEDLINE; 85061571.

RA Gidoni D., Dynan W. S., Tjian R.
 RT Multiple specific contacts
between a mammalian transcription factor and its
 RT cognate
promoters
 RL Nature 312:409-413 (1984).
 RN [75]; RE0000122.

RX MEDLINE; 84026540.
 RA Dynan W. S., Tjian R.
 RT The
Promoter-Specific transcription Factor Sp1 Binds to Upstream Sequences

RT in the Sv40 Early Promoter
 RL Cell 35:79-87 (1983).

XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

261 genes, 261 accessions (Toggle view)

AccessionGeneTitleLinks
NXPH4NXPH4neurexophilin 4Source|GeneCards
FBXO36FBXO36F-box protein 36Source|GeneCards
KIAA0252RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)Source|GeneCards
PSMC6PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 6Source|GeneCards
FLJ90013FLJ90013hypothetical protein FLJ90013Source|GeneCards
FLJ90811PUSL1pseudouridylate synthase-like 1Source|GeneCards
LOC90557LOC90557hypothetical protein BC016861Source|GeneCards
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)Source|GeneCards
PEX14PEX14peroxisomal biogenesis factor 14Source|GeneCards
CBLN1CBLN1cerebellin 1 precursorSource|GeneCards
APLP2APLP2amyloid beta (A4) precursor-like protein 2Source|GeneCards
GGA1GGA1golgi associated, gamma adaptin ear containing, ARF binding protein 1Source|GeneCards
FLJ40342FLJ40342hypothetical protein FLJ40342Source|GeneCards
SLC18A3SLC18A3solute carrier family 18 (vesicular acetylcholine), member 3Source|GeneCards
TAF11TAF11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDaSource|GeneCards
NXPH3NXPH3neurexophilin 3Source|GeneCards
TMEM24TMEM24transmembrane protein 24Source|GeneCards
BHC80PHF21APHD finger protein 21ASource|GeneCards
KCNB1KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1Source|GeneCards
IQGAP1IQGAP1IQ motif containing GTPase activating protein 1Source|GeneCards
CRYABCRYABcrystallin, alpha BSource|GeneCards
NLKNLKnemo like kinaseSource|GeneCards
ASCL2ASCL2achaete-scute complex-like 2 (Drosophila)Source|GeneCards
CKAP1CKAP1cytoskeleton associated protein 1Source|GeneCards
DKFZP434E2321DKFZP434E2321hypothetical protein DKFZp434E2321Source|GeneCards
SLC9A6SLC9A6solute carrier family 9 (sodium/hydrogen exchanger), isoform 6Source|GeneCards
SOX12SOX12SRY (sex determining region Y)-box 12Source|GeneCards
CHKACHKAcholine kinase alphaSource|GeneCards
CDC40CDC40cell division cycle 40 homolog (yeast)Source|GeneCards
LOC57149LOC57149hypothetical protein A-211C6.1Source|GeneCards
CORO1CCORO1Ccoronin, actin binding protein, 1CSource|GeneCards
DMTF1DMTF1cyclin D binding myb-like transcription factor 1Source|GeneCards
LOC114926LOC114926hypothetical protein BC013035Source|GeneCards
CRY1CRY1cryptochrome 1 (photolyase-like)Source|GeneCards
PPP1R3DPPP1R3Dprotein phosphatase 1, regulatory subunit 3DSource|GeneCards
DKFZP566M1046DKFZP566M1046hypothetical protein DKFZp566M1046Source|GeneCards
MXD4MXD4MAX dimerization protein 4Source|GeneCards
PAK4PAK4p21(CDKN1A)-activated kinase 4Source|GeneCards
SNAPAPSNAPAPSNARE associated protein snapinSource|GeneCards
HIPK1HIPK1homeodomain interacting protein kinase 1Source|GeneCards
LOC149420LOC149420casein kinaseSource|GeneCards
ELLELLelongation factor RNA polymerase IISource|GeneCards
MGC10871RBM30RNA binding motif protein 30Source|GeneCards
FLJ35827EML3echinoderm microtubule associated protein like 3Source|GeneCards
SH2BP1SH2BP1SH2 domain binding protein 1 (tetratricopeptide repeat containing)Source|GeneCards
DNCL1DNCL1dynein, cytoplasmic, light polypeptide 1Source|GeneCards
EFEMP2EFEMP2EGF-containing fibulin-like extracellular matrix protein 2Source|GeneCards
SNX2SNX2sorting nexin 2Source|GeneCards
RNF110PCGF2polycomb group ring finger 2Source|GeneCards
FBXL11FBXL11F-box and leucine-rich repeat protein 11Source|GeneCards
ZFYVE16ZFYVE16zinc finger, FYVE domain containing 16Source|GeneCards
TLX2TLX2T-cell leukemia, homeobox 2Source|GeneCards
ACVR2ACVR2activin A receptor, type IISource|GeneCards
MGC2941PHF23PHD finger protein 23Source|GeneCards
C20ORF67C20ORF67chromosome 20 open reading frame 67Source|GeneCards
SPATA6SPATA6spermatogenesis associated 6Source|GeneCards
HYAL2HYAL2hyaluronoglucosaminidase 2Source|GeneCards
HRMT1L2HRMT1L2HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)Source|GeneCards
RAB9ARAB9ARAB9A, member RAS oncogene familySource|GeneCards
SIPA1SIPA1signal-induced proliferation-associated gene 1Source|GeneCards
TIEG2KLF11Kruppel-like factor 11Source|GeneCards
LOC143425LOC143425similar to synaptotagmin VSource|GeneCards
LDB1LDB1LIM domain binding 1Source|GeneCards
TCF4TCF4Transcription factor 4Source|GeneCards
FLJ39653FLJ39653hypothetical protein FLJ39653Source|GeneCards
IRX3IRX3iroquois homeobox protein 3Source|GeneCards
COPS5COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)Source|GeneCards
GLIGLI1glioma-associated oncogene homolog 1 (zinc finger protein)Source|GeneCards
SLBPSLBPstem-loop (histone) binding proteinSource|GeneCards
CPDCPDcarboxypeptidase DSource|GeneCards
POU3F2POU3F2POU domain, class 3, transcription factor 2Source|GeneCards
ROM1ROM1retinal outer segment membrane protein 1Source|GeneCards
PIAS3PIAS3protein inhibitor of activated STAT3Source|GeneCards
RAB2BRAB2BRAB2B, member RAS oncogene familySource|GeneCards
C14ORF50C14ORF50chromosome 14 open reading frame 50Source|GeneCards
SNAG1SNAG1sorting nexin associated golgi protein 1Source|GeneCards
MAP3K11MAP3K11mitogen-activated protein kinase kinase kinase 11Source|GeneCards
CACNA1DCACNA1Dcalcium channel, voltage-dependent, L type, alpha 1D subunitSource|GeneCards
C20ORF23C20ORF23chromosome 20 open reading frame 23Source|GeneCards
PIAS1PIAS1protein inhibitor of activated STAT, 1Source|GeneCards
SPAG9SPAG9sperm associated antigen 9Source|GeneCards
RBBP7RBBP7retinoblastoma binding protein 7Source|GeneCards
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)Source|GeneCards
ZNF524ZNF524zinc finger protein 524Source|GeneCards
GCN5L2GCN5L2GCN5 general control of amino-acid synthesis 5-like 2 (yeast)Source|GeneCards
CACNA1BCACNA1Bcalcium channel, voltage-dependent, L type, alpha 1B subunitSource|GeneCards
SH3KBP1SH3KBP1SH3-domain kinase binding protein 1Source|GeneCards
WASF1WASF1WAS protein family, member 1Source|GeneCards
ANP32AANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member ASource|GeneCards
G22P1G22P1thyroid autoantigen 70kDa (Ku antigen)Source|GeneCards
SMARCA5SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5Source|GeneCards
ARHGEF1ARHGEF1Rho guanine nucleotide exchange factor (GEF) 1Source|GeneCards
POLR2IPOLR2Ipolymerase (RNA) II (DNA directed) polypeptide I, 14.5kDaSource|GeneCards
LHX3LHX3LIM homeobox 3Source|GeneCards
SH2D3CSH2D3CSH2 domain containing 3CSource|GeneCards
MGC3794TIPRLTIP41, TOR signalling pathway regulator-like (S. cerevisiae)Source|GeneCards
EDG8EDG8endothelial differentiation, sphingolipid G-protein-coupled receptor, 8Source|GeneCards
CGI-48WDR50WD repeat domain 50Source|GeneCards
FLJ20920FLJ20920hypothetical protein FLJ20920Source|GeneCards
NYREN18NYREN18NEDD8 ultimate buster-1Source|GeneCards
MGC14376MGC14376hypothetical protein MGC14376Source|GeneCards
RPL7RPL7ribosomal protein L7Source|GeneCards
TRPC4APTRPC4APtransient receptor potential cation channel, subfamily C, member 4 associated proteinSource|GeneCards
GLTPGLTPglycolipid transfer proteinSource|GeneCards
ZNF282ZNF282zinc finger protein 282Source|GeneCards
CGGBP1CGGBP1CGG triplet repeat binding protein 1Source|GeneCards
SH3BP5SH3BP5SH3-domain binding protein 5 (BTK-associated)Source|GeneCards
RHBDL4RHBDL4rhomboid, veinlet-like 4 (Drosophila)Source|GeneCards
ZNF553ZNF553zinc finger protein 553Source|GeneCards
HES7HES7hairy and enhancer of split 7 (Drosophila)Source|GeneCards
CSNK1DCSNK1Dcasein kinase 1, deltaSource|GeneCards
GGNGGNgametogenetinSource|GeneCards
LPPR2LPPR2lipid phosphate phosphatase-related protein type 2Source|GeneCards
PRKRAPRKRAprotein kinase, interferon-inducible double stranded RNA dependent activatorSource|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
NDRG1NDRG1N-myc downstream regulated gene 1Source|GeneCards
CHD6CHD6chromodomain helicase DNA binding protein 6Source|GeneCards
NEF3NEF3neurofilament 3 (150kDa medium)Source|GeneCards
FLJ21839FLJ21839hypothetical protein FLJ21839Source|GeneCards
DLC2STARD13START domain containing 13Source|GeneCards
CYP26B1CYP26B1cytochrome P450, family 26, subfamily B, polypeptide 1Source|GeneCards
ACCN2ACCN2amiloride-sensitive cation channel 2, neuronalSource|GeneCards
PRSS12PRSS12protease, serine, 12 (neurotrypsin, motopsin)Source|GeneCards
FEVFEVFEV (ETS oncogene family)Source|GeneCards
GOLGA3GOLGA3golgi autoantigen, golgin subfamily a, 3Source|GeneCards
PHOX2APHOX2Apaired-like (aristaless) homeobox 2aSource|GeneCards
PER1PER1period homolog 1 (Drosophila)Source|GeneCards
SMARCE1SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1Source|GeneCards
ELK1ELK1ELK1, member of ETS oncogene familySource|GeneCards
PHCAPHCAphytoceramidase, alkalineSource|GeneCards
C11ORF30C11ORF30chromosome 11 open reading frame 30Source|GeneCards
CDKL5CDKL5cyclin-dependent kinase-like 5Source|GeneCards
IMP-1IMP-1IGF-II mRNA-binding protein 1Source|GeneCards
SMCR7SMCR7Smith-Magenis syndrome chromosome region, candidate 7Source|GeneCards
HUMAGCGBRBM15BRNA binding motif protein 15BSource|GeneCards
NRG2NRG2neuregulin 2Source|GeneCards
FNTAFNTAfarnesyltransferase, CAAX box, alphaSource|GeneCards
TIMP3TIMP3tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)Source|GeneCards
RELARELAv-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)Source|GeneCards
FLIIFLIIflightless I homolog (Drosophila)Source|GeneCards
ZFP91ZFP91zinc finger protein 91 homolog (mouse)Source|GeneCards
FGF12FGF12fibroblast growth factor 12Source|GeneCards
MYLIPMYLIPmyosin regulatory light chain interacting proteinSource|GeneCards
MAP2K7MAP2K7mitogen-activated protein kinase kinase 7Source|GeneCards
KCNQ4KCNQ4potassium voltage-gated channel, KQT-like subfamily, member 4Source|GeneCards
FLJ23861FLJ23861hypothetical protein FLJ23861Source|GeneCards
DKFZP586B1621DAKdihydroxyacetone kinase 2 homolog (yeast)Source|GeneCards
AKT2AKT2v-akt murine thymoma viral oncogene homolog 2Source|GeneCards
POU5F1POU5F1POU domain, class 5, transcription factor 1Source|GeneCards
GRB2GRB2growth factor receptor-bound protein 2Source|GeneCards
MGC15716ZNF414zinc finger protein 414Source|GeneCards
HCN4HCN4hyperpolarization activated cyclic nucleotide-gated potassium channel 4Source|GeneCards
ANKS1ANKS1ankyrin repeat and sterile alpha motif domain containing 1Source|GeneCards
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)Source|GeneCards
CHATCHATCholine acetyltransferaseSource|GeneCards
ING1LING2inhibitor of growth family, member 2Source|GeneCards
CLSTN1CLSTN1calsyntenin 1Source|GeneCards
ERBB3ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)Source|GeneCards
TAF6TAF6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDaSource|GeneCards
FLJ20477PIGVphosphatidylinositol glycan, class VSource|GeneCards
FLJ30058FLJ30058hypothetical protein FLJ30058Source|GeneCards
GASPGPRASP1G protein-coupled receptor associated sorting protein 1Source|GeneCards
LOC283932LOC283932hypothetical protein LOC283932Source|GeneCards
PHF15PHF15PHD finger protein 15Source|GeneCards
NFAT5NFAT5nuclear factor of activated T-cells 5, tonicity-responsiveSource|GeneCards
ZBTB5ZBTB5zinc finger and BTB domain containing 5Source|GeneCards
BCL6BBCL6BB-cell CLL/lymphoma 6, member B (zinc finger protein)Source|GeneCards
RFPRFPRet finger proteinSource|GeneCards
KIAA0276DCUN1D4DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)Source|GeneCards
NFYCNFYCnuclear transcription factor Y, gammaSource|GeneCards
MAP4K2MAP4K2mitogen-activated protein kinase kinase kinase kinase 2Source|GeneCards
UGP2UGP2UDP-glucose pyrophosphorylase 2Source|GeneCards
HSPB9HSPB9small heat shock protein B9Source|GeneCards
NXFNPAS4neuronal PAS domain protein 4Source|GeneCards
GKGKGlycerol kinaseSource|GeneCards
MGC40107MGC40107hypothetical protein MGC40107Source|GeneCards
OSBPL9OSBPL9oxysterol binding protein-like 9Source|GeneCards
ELKSRAB6IP2RAB6 interacting protein 2Source|GeneCards
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)Source|GeneCards
RNF24RNF24ring finger protein 24Source|GeneCards
ATP2A2ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2Source|GeneCards
TTC11TTC11tetratricopeptide repeat domain 11Source|GeneCards
E2-230KE2-230Klikely ortholog of mouse ubiquitin-conjugating enzyme E2-230KSource|GeneCards
RHOGRHOGras homolog gene family, member G (rho G)Source|GeneCards
ASC1P100ASCC2activating signal cointegrator 1 complex subunit 2Source|GeneCards
C11ORF4MRPL49mitochondrial ribosomal protein L49Source|GeneCards
RAP1GDS1RAP1GDS1RAP1, GTP-GDP dissociation stimulator 1Source|GeneCards
SPG4SPG4spastic paraplegia 4 (autosomal dominant; spastin)Source|GeneCards
IGSF4IGSF4immunoglobulin superfamily, member 4Source|GeneCards
HTR7HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)Source|GeneCards
ONECUT1ONECUT1one cut domain, family member 1Source|GeneCards
HAP1HAP1huntingtin-associated protein 1 (neuroan 1)Source|GeneCards
DDAH2DDAH2dimethylarginine dimethylaminohydrolase 2Source|GeneCards
DRAP1DRAP1DR1-associated protein 1 (negative cofactor 2 alpha)Source|GeneCards
NTF5NTF5neurotrophin 5 (neurotrophin 4/5)Source|GeneCards
MAP3K7MAP3K7mitogen-activated protein kinase kinase kinase 7Source|GeneCards
GAS7GAS7growth arrest-specific 7Source|GeneCards
FAPP2PLEKHA8Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8Source|GeneCards
WNT2WNT2wingless-type MMTV integration site family member 2Source|GeneCards
FLJ90024FLJ90024fasting-inducible integral membrane protein TM6P1Source|GeneCards
PMM1PMM1phosphomannomutase 1Source|GeneCards
ME3ME3malic enzyme 3, NADP(+)-dependent, mitochondrialSource|GeneCards
SMARCD1SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1Source|GeneCards
VPRBPVPRBPVpr-binding proteinSource|GeneCards
CDCA7CDCA7cell division cycle associated 7Source|GeneCards
VKORC1L1VKORC1L1vitamin K epoxide reductase complex, subunit 1-like 1Source|GeneCards
FKBP8FKBP8FK506 binding protein 8, 38kDaSource|GeneCards
KCNN2KCNN2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
CDC25ACDC25Acell division cycle 25ASource|GeneCards
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2ASource|GeneCards
MGC40499MGC40499hypothetical protein MGC40499Source|GeneCards
C9ORF37C9ORF37chromosome 9 open reading frame 37Source|GeneCards
EPS15EPS15epidermal growth factor receptor pathway substrate 15Source|GeneCards
KIAA1259KIAA1259hypothetical protein KIAA1259Source|GeneCards
ACEACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1Source|GeneCards
WNT2BWNT2Bwingless-type MMTV integration site family, member 2BSource|GeneCards
TRIM28TRIM28tripartite motif-containing 28Source|GeneCards
TEAD2TEAD2TEA domain family member 2Source|GeneCards
CNNM4CNNM4cyclin M4Source|GeneCards
PTOV1PTOV1prostate tumor overexpressed gene 1Source|GeneCards
KLF13KLF13Kruppel-like factor 13Source|GeneCards
PITPNPITPNAPhosphatidylinositol transfer protein, alphaSource|GeneCards
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunitSource|GeneCards
PTK7PTK7PTK7 protein tyrosine kinase 7Source|GeneCards
ROD1ROD1ROD1 regulator of differentiation 1 (S. pombe)Source|GeneCards
HSPB2HSPB2heat shock 27kDa protein 2Source|GeneCards
P5326P5326hypothetical protein p5326Source|GeneCards
DDB1DDB1damage-specific DNA binding protein 1, 127kDaSource|GeneCards
CDC37CDC37CDC37 cell division cycle 37 homolog (S. cerevisiae)Source|GeneCards
PTPN2PTPN2protein tyrosine phosphatase, non-receptor type 2Source|GeneCards
THRATHRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Source|GeneCards
TIMELESSTIMELESStimeless homolog (Drosophila)Source|GeneCards
SOX2SOX2SRY (sex determining region Y)-box 2Source|GeneCards
C20ORF177C20ORF177chromosome 20 open reading frame 177Source|GeneCards
FLJ33817FLJ33817hypothetical protein FLJ33817Source|GeneCards
SLC35F5SLC35F5solute carrier family 35, member F5Source|GeneCards
FKBP14FKBP14FK506 binding protein 14, 22 kDaSource|GeneCards
ANKRD25ANKRD25ankyrin repeat domain 25Source|GeneCards
OAZ2OAZ2ornithine decarboxylase antizyme 2Source|GeneCards
DKFZP547A023CTTNBP2NLCTTNBP2 N-terminal likeSource|GeneCards
GNA11GNA11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)Source|GeneCards
UPF2UPF2UPF2 regulator of nonsense transcripts homolog (yeast)Source|GeneCards
CAMK2GCAMK2Gcalcium/calmodulin-dependent protein kinase (CaM kinase) II gammaSource|GeneCards
LOXL4LOXL4lysyl oxidase-like 4Source|GeneCards
KLF2KLF2Kruppel-like factor 2 (lung)Source|GeneCards
IGSF4DIGSF4Dimmunoglobulin superfamily, member 4DSource|GeneCards
ERO1LBERO1LBERO1-like beta (S. cerevisiae)Source|GeneCards
DFNB31DFNB31deafness, autosomal recessive 31Source|GeneCards
GPR3GPR3G protein-coupled receptor 3Source|GeneCards
FLJ23420LRRC8Eleucine rich repeat containing 8 family, member ESource|GeneCards
STMN1STMN1stathmin 1/oncoprotein 18Source|GeneCards
BADBADBCL2-antagonist of cell deathSource|GeneCards
LMO6LMO6LIM domain only 6Source|GeneCards
BCL2L2BCL2L2BCL2-like 2Source|GeneCards
NCOA6NCOA6nuclear receptor coactivator 6Source|GeneCards
MGC9564MGC9564similar to RIKEN cDNA 1110002C08 geneSource|GeneCards
CREB1CREB1cAMP responsive element binding protein 1Source|GeneCards
PPARGC1BPPARGC1Bperoxisome proliferative activated receptor, gamma, coactivator 1, betaSource|GeneCards
FLJ31842TMEM56transmembrane protein 56Source|GeneCards
ABHD1ABHD1abhydrolase domain containing 1Source|GeneCards

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