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Gene set: V$STAT5A_02 (C3:TFAC:0244)
Standard nameV$STAT5A_02
Systematic nameC3:TFAC:0244
Brief descriptionGenes with 3'UTR containing motif TTCCNRGAANNNNNNTTCCNNGRR which matches annotation for STAT5A: signal transducer and activator of transcription 5A
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA STAT5A
 XX
 SY signal transducer
and activator of transcription 5a.
 XX
 OS human, Homo sapiens

OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda;
mammalia;
 OC eutheria; primates
 XX
 XX
 CL C0039;
STAT.
 XX
 SZ 794 AA; 90.6 kDa (calc)
 XX
 XX

SC translated from EMBL #L41142
 XX
 FT 2 126 PF02865; STAT_prot.

FT 138 330 PF01017; STAT.
 FT 332 583 PF02864; STAT_bind.

FT 587 700 SM00252; SH2.
 FT 589 670 PF00017; SH2.
 XX

SF binds as homodimer and homotetramer to consensus GAS (interferon

SF gamma-activated sequences) motifs TTC(T/C)N(G/A)GAA [1];

SF STAT5A tetramers bind to two tandem repeated GAS sites with
an optimal
 SF spacing of 6 bp [1];
 SF STAT5A binds to
the beta-casein promoter as well as to the CIS promoter as

SF a tetramer [2];
 XX
 XX
 XX
 XX
 RN [1]; RE0016782.

RX MEDLINE; 20063198.
 RA Soldaini E., John S., Moro S., Bollenbacher
J., Schindler U., Leonard W. J.
 RT DNA binding site selection
of dimeric and tetrameric Stat5 proteins reveals
 RT a large
repertoire of divergent tetrameric Stat5a binding sites.
 RL
Mol. Cell. Biol. 20:389-401 (2000).
 RN [2]; RE0023467.

RX MEDLINE; 9742102.
 RA Verdier F., Rabionet R., Gouilleux
F., Beisenherz-Huss C., Varlet P.,
 RA Muller O., Mayeux P.,
Lacombe C., Gisselbrecht S., Chretien S.
 RT A sequence of
the CIS gene promoter interacts preferentially with two
 RT
associated STAT5A dimers: a distinct biochemical difference between
STAT5A
 RT and STAT5B.
 RL Mol. Cell. Biol. 18:5852-5860
(1998).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

146 genes, 146 accessions (Toggle view)

AccessionGeneTitleLinks
BTEB1KLF9Kruppel-like factor 9Source|GeneCards
WNT10AWNT10Awingless-type MMTV integration site family, member 10ASource|GeneCards
DSG1DSG1desmoglein 1Source|GeneCards
ZNF184ZNF184zinc finger protein 184 (Kruppel-like)Source|GeneCards
ATF4ATF4activating transcription factor 4 (tax-responsive enhancer element B67)Source|GeneCards
STC1STC1stanniocalcin 1Source|GeneCards
IL9IL9interleukin 9Source|GeneCards
ELMO1ELMO1engulfment and cell motility 1 (ced-12 homolog, C. elegans)Source|GeneCards
ATP5JATP5JATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6Source|GeneCards
ABHD7ABHD7abhydrolase domain containing 7Source|GeneCards
DDX25DDX25DEAD (Asp-Glu-Ala-Asp) box polypeptide 25Source|GeneCards
OPN3OPN3opsin 3 (encephalopsin, panopsin)Source|GeneCards
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
ARF3ARF3ADP-ribosylation factor 3Source|GeneCards
FLJ32112C1ORF83chromosome 1 open reading frame 83Source|GeneCards
SCN2A2SCN2A2sodium channel, voltage-gated, type II, alpha 2Source|GeneCards
NFATC2NFATC2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2Source|GeneCards
MGC26988FAM71Bfamily with sequence similarity 71, member BSource|GeneCards
BDNFBDNFbrain-derived neurotrophic factorSource|GeneCards
C20ORF152C20ORF152chromosome 20 open reading frame 152Source|GeneCards
FLJ33651FLJ33651hypothetical protein FLJ33651Source|GeneCards
ERBB4ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)Source|GeneCards
ZNF180ZNF180zinc finger protein 180 (HHZ168)Source|GeneCards
C9ORF99HSDL2Hydroxysteroid dehydrogenase like 2Source|GeneCards
DDX17DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17Source|GeneCards
PCSK2PCSK2proprotein convertase subtilisin/kexin type 2Source|GeneCards
VIPVIPvasoactive intestinal peptideSource|GeneCards
ZNF278ZNF278zinc finger protein 278Source|GeneCards
LAMA1LAMA1laminin, alpha 1Source|GeneCards
SP110SP110SP110 nuclear body proteinSource|GeneCards
IRF2BP1IRF2BP1interferon regulatory factor 2 binding protein 1Source|GeneCards
SOCS2SOCS2suppressor of cytokine signaling 2Source|GeneCards
LOC57149LOC57149hypothetical protein A-211C6.1Source|GeneCards
MGC34713MGC34713hypothetical protein MGC34713Source|GeneCards
HNF4GHNF4Ghepatocyte nuclear factor 4, gammaSource|GeneCards
GLRA2GLRA2glycine receptor, alpha 2Source|GeneCards
BCL2L1BCL2L1BCL2-like 1Source|GeneCards
DARSDARSaspartyl-tRNA synthetaseSource|GeneCards
C6ORF80C6ORF80chromosome 6 open reading frame 80Source|GeneCards
CHD2CHD2chromodomain helicase DNA binding protein 2Source|GeneCards
BCL6BCL6B-cell CLL/lymphoma 6 (zinc finger protein 51)Source|GeneCards
GSNGSNgelsolin (amyloidosis, Finnish type)Source|GeneCards
CCND2CCND2cyclin D2Source|GeneCards
ATOH8ATOH8Atonal homolog 8 (Drosophila)Source|GeneCards
TIAL1TIAL1TIA1 cytotoxic granule-associated RNA binding protein-like 1Source|GeneCards
LOC339168LOC339168hypothetical protein LOC339168Source|GeneCards
CACNB2CACNB2calcium channel, voltage-dependent, beta 2 subunitSource|GeneCards
ACOX3ACOX3acyl-Coenzyme A oxidase 3, pristanoylSource|GeneCards
GRID2GRID2glutamate receptor, ionotropic, delta 2Source|GeneCards
PILRBPILRBpaired immunoglobin-like type 2 receptor betaSource|GeneCards
LOC115509LOC115509hypothetical protein BC014000Source|GeneCards
TLX2TLX2T-cell leukemia, homeobox 2Source|GeneCards
POU6F2POU6F2POU domain, class 6, transcription factor 2Source|GeneCards
7H3SYDE1synapse defective 1, Rho GTPase, homolog 1 (C. elegans)Source|GeneCards
LRRN3LRRN3leucine rich repeat neuronal 3Source|GeneCards
PMS2L5PMS2L5postmeiotic segregation increased 2-like 5Source|GeneCards
SSBP3SSBP3single stranded DNA binding protein 3Source|GeneCards
FLJ10415FLJ10415hypothetical protein FLJ10415Source|GeneCards
DYRK2DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2Source|GeneCards
IPO11IPO11importin 11Source|GeneCards
SYMPKSYMPKsymplekinSource|GeneCards
C10ORF3C10ORF3chromosome 10 open reading frame 3Source|GeneCards
EMP1EMP1epithelial membrane protein 1Source|GeneCards
A2BP1A2BP1ataxin 2-binding protein 1Source|GeneCards
CYP46A1CYP46A1cytochrome P450, family 46, subfamily A, polypeptide 1Source|GeneCards
ARL4AARL4ADP-ribosylation factor-like 4Source|GeneCards
LOC90768LOC90768hypothetical protein LOC90768Source|GeneCards
MAT1AMAT1Amethionine adenosyltransferase I, alphaSource|GeneCards
NTF5NTF5neurotrophin 5 (neurotrophin 4/5)Source|GeneCards
PRDM13PRDM13PR domain containing 13Source|GeneCards
MGC48972DCUN1D3DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)Source|GeneCards
DKFZP434I099C16ORF50chromosome 16 open reading frame 50Source|GeneCards
KCNJ8KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8Source|GeneCards
RARARARAretinoic acid receptor, alphaSource|GeneCards
MGC15912MGC15912hypothetical protein MGC15912Source|GeneCards
LOC153222LOC153222adult retina proteinSource|GeneCards
SNAG1SNAG1sorting nexin associated golgi protein 1Source|GeneCards
NAP5NAP5Nck-associated protein 5Source|GeneCards
MBNL3MBNL3muscleblind-like 3 (Drosophila)Source|GeneCards
OBSCNOBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEFSource|GeneCards
PTCHPTCHpatched homolog (Drosophila)Source|GeneCards
GABPAGABPAGA binding protein transcription factor, alpha subunit 60kDaSource|GeneCards
TRAF6TRAF6TNF receptor-associated factor 6Source|GeneCards
C1ORF8TMEM59transmembrane protein 59Source|GeneCards
RBM21RBM21RNA binding motif protein 21Source|GeneCards
MGC34034MGC34034hypothetical protein MGC34034Source|GeneCards
SPTBN2SPTBN2spectrin, beta, non-erythrocytic 2Source|GeneCards
KITLGKITLGKIT ligandSource|GeneCards
SDC1SDC1syndecan 1Source|GeneCards
MGRN1MGRN1mahogunin, ring finger 1Source|GeneCards
SREBF1SREBF1sterol regulatory element binding transcription factor 1Source|GeneCards
DKFZP434C0328DKFZP434C0328hypothetical protein DKFZp434C0328Source|GeneCards
AP1G2AP1G2adaptor-related protein complex 1, gamma 2 subunitSource|GeneCards
MBNL1MBNL1muscleblind-like (Drosophila)Source|GeneCards
SMC1L1SMC1L1SMC1 structural maintenance of chromosomes 1-like 1 (yeast)Source|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
GBX2GBX2gastrulation brain homeo box 2Source|GeneCards
FOXA3FOXA3forkhead box A3Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
POLAPOLApolymerase (DNA directed), alphaSource|GeneCards
IL1RNIL1RNinterleukin 1 receptor antagonistSource|GeneCards
TAL1TAL1T-cell acute lymphocytic leukemia 1Source|GeneCards
FLJ13195FLJ13195hypothetical protein FLJ13195 similar to stromal antigen 3Source|GeneCards
MITFMITFmicrophthalmia-associated transcription factorSource|GeneCards
CREMCREMcAMP responsive element modulatorSource|GeneCards
GFAPGFAPglial fibrillary acidic proteinSource|GeneCards
RAB37RAB37RAB37, member of RAS oncogene familySource|GeneCards
STARD3STARD3START domain containing 3Source|GeneCards
PDK4PDK4pyruvate dehydrogenase kinase, isoenzyme 4Source|GeneCards
PCDH9PCDH9protocadherin 9Source|GeneCards
FLJ10408FAM90A1family with sequence similarity 90, member A1Source|GeneCards
C9ORF48C9ORF48chromosome 9 open reading frame 48Source|GeneCards
MPP6MPP6membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)Source|GeneCards
RUNX1RUNX1runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)Source|GeneCards
GABRB1GABRB1gamma-aminobutyric acid (GABA) A receptor, beta 1Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
CDC37L1CDC37L1Cell division cycle 37 homolog (S. cerevisiae)-like 1Source|GeneCards
GJA5GJA5gap junction protein, alpha 5, 40kDa (connexin 40)Source|GeneCards
BMP5BMP5bone morphogenetic protein 5Source|GeneCards
CITED4CITED4Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4Source|GeneCards
KIAA0672KIAA0672KIAA0672 gene productSource|GeneCards
FZD6FZD6frizzled homolog 6 (Drosophila)Source|GeneCards
OXA1LOXA1Loxidase (cytochrome c) assembly 1-likeSource|GeneCards
SHRMLSHRMLShroom-related proteinSource|GeneCards
ZNF42ZNF42zinc finger protein 42 (myeloid-specific retinoic acid-responsive)Source|GeneCards
ZNF384ZNF384zinc finger protein 384Source|GeneCards
ENPP2ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)Source|GeneCards
LHX6LHX6LIM homeobox 6Source|GeneCards
TRIM47TRIM47tripartite motif-containing 47Source|GeneCards
CDC10SEPT7septin 7Source|GeneCards
BTRCBTRCbeta-transducin repeat containingSource|GeneCards
HYPBHYPBhuntingtin interacting protein BSource|GeneCards
KLF4KLF4Kruppel-like factor 4 (gut)Source|GeneCards
BTKBTKBruton agammaglobulinemia tyrosine kinaseSource|GeneCards
SRPXSRPXsushi-repeat-containing protein, X-linkedSource|GeneCards
GPRC5CGPRC5CG protein-coupled receptor, family C, group 5, member CSource|GeneCards
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3Source|GeneCards
MGC17839MGC17839hypothetical protein MGC17839Source|GeneCards
PPP1R16BPPP1R16Bprotein phosphatase 1, regulatory (inhibitor) subunit 16BSource|GeneCards
ASXL1ASXL1additional sex combs like 1 (Drosophila)Source|GeneCards
ZNF423ZNF423zinc finger protein 423Source|GeneCards
TRADRAD51L3RAD51-like 3 (S. cerevisiae)Source|GeneCards
ZFRZFRzinc finger RNA binding proteinSource|GeneCards
FOSFOSv-fos FBJ murine osteosarcoma viral oncogene homologSource|GeneCards
HOXB6HOXB6homeo box B6Source|GeneCards
PTPN21PTPN21protein tyrosine phosphatase, non-receptor type 21Source|GeneCards

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