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Gene set: V$TAL1ALPHAE47_01 (C3:TFAC:0034)
Standard nameV$TAL1ALPHAE47_01
Systematic nameC3:TFAC:0034
Brief descriptionGenes with 3'UTR containing motif NNNAACAGATGKTNNN which matches annotation for TAL1: T-cell acute lymphocytic leukemia 1
TCF3: Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA Tal-1
 XX
 SY SCL; Tal-1; TCL5;
pp42-TAL1; Tal-1alpha; T-cell acute lymphocytic
 SY leukemia-1
protein; stem-cell leukemia protein.
 XX
 OS human, Homo
sapiens
 OC eukaryota; animalia; metazoa; chordata; vertebrata;
tetrapoda; mammalia;
 OC eutheria; primates
 XX
 CL C0010;
bHLH; 1.2.4.1.1.1.
 XX
 SZ 331 AA; 34.3 kDa (cDNA)
 XX

XX
 SC SwissProt #P17542
 XX
 FT 117 175 major trans-activating
domain [6].
 FT 176 176 alternative translation initiation
codon (TAL-1beta).
 FT 188 199 basic region.
 FT 188 240
PF00010; HLH.
 FT 193 245 SM00353; HLH.
 FT 200 240 helix-loop-helix
domain.
 FT 263 274 glycine-rich region (11/12).
 XX

SF N-terminally truncated forms arise from alternative translation
initiation
 SF at Met-26 (p39) or Met-176 (p22) [8];
 SF
the eight exons give rise to several splice variants [13];

SF no homodimers, no intrinsic DNA-binding capability, but DNA-binding

SF heterodimers with class A bHLH factors [11] [4];
 SF binding
sites contain one E-box-like half (AACAG) and one which is

SF contacted by Tal-1 (ATGGT) [4];
 SF Tal-1 peptides can be
phosphorylated at serine residues [10];
 SF multiple trans-activating
domains within 1-175 [6];
 SF Tal-1 complexes with LIM-proteins
Lmo2/RBTN2 in erythroid cells and
 SF Lmo1/RBTN1 in T-ALL cells
[3] [7];
 SF RBTN-interactions depend on an intact bHLH domain
and occur simultaneously
 SF with E47 heterodimerization [3];

SF specific for the bHLH domains of the Tal-1/Tal-2/Lyl-2 family
and for RBTN
 SF LIM proteins [3];
 XX
 CP erythroid
cells [5], early hematopoietic tissues, fetal liver [17]
 XX

FF activator [6];
 FF positive regulator of erythroid differentiation
[5];
 FF TAL1 gene rearrangements in patients with T-cell acute
lymphoblastic
 FF leukemia [16];
 FF most observed breakpoints
are between exons Ia and Ib within the 5'-UTR of
 FF the transcribed
region [14];
 FF after chromosomal translocation or deletion
leading to inappropriate
 FF expression, it may promoter erythroleukemia
[10];
 FF a C-terminally truncated variant found in a Jurkat
cell subline appears to
 FF cause premature apoptosis after
serum deprivation [1];
 XX
 IN T00204; E12; human, Homo
sapiens.
 IN T00207; E47; human, Homo sapiens.
 IN T00674;
E47; rat, Rattus norvegicus.
 IN T01788; E47; mouse, Mus musculus.

IN T00405; IEBP1; rat, Rattus norvegicus.
 IN T00433; ITF-2;
human, Homo sapiens.
 IN T02249; Lmo1; human, Homo sapiens.

IN T02250; Lmo2; human, Homo sapiens.
 XX
 XX
 XX

XX
 RN [1]; RE0005821.
 RX MEDLINE; 95292975.
 RA Leroy-Viard
K., Vinit M.-A., Lecointe N., Jouault H., Hibner U., Romeo

RA P.-H., Mathieu-Mahul D.
 RT Loss of TAL-1 protein activity
induces premature apoptosis of Jurkat
 RT leukemic T cells
upon medium depletion
 RL EMBO J. 14:2341-2349 (1995).

RN [2]; RE0002932.
 RX MEDLINE; 94119077.
 RA Hsu H.-L.,
Huang L., Tsan J. T., Funk W., Wright W. E., Hu J.-S., Kingston

RA R. E., Baer R.
 RT Preferred sequences for DNA recognition
by the TAL1 helix-loop-helix
 RT proteins
 RL Mol. Cell.
Biol. 14:1256-1265 (1994).
 RN [3]; RE0003640.
 RX MEDLINE;
95045374.
 RA Wadman I., Li J., Bash R. O., Forster A., Osada
H., Rabbitts T. H., Baer R.
 RT Specific in vivo association
between the bHLH and LIM proteins implicated
 RT in human T
cell leukemia
 RL EMBO J. 13:4831-4839 (1994).
 RN [4];
RE0004023.
 RX MEDLINE; 94119077.
 RA Hsu H.-L., Huang L.,
Tsan J. T., Funk W., Wright W. E., Hu J.-S., Klingston
 RA
R. E., Baer R.
 RT Preferred sequence for DNA recognition by
the TAL1 helix-loop-helix proteins
 RL Mol. Cell. Biol. 14:1256-1265
(1994).
 RN [5]; RE0004039.
 RX MEDLINE; 94344763.
 RA
Carver L. A., Hogenesch J. B., Bradfield C. A.
 RT Tissue specific
expression of the rat Ah-receptor and ARNT mRNAs
 RL Nucleic
Acids Res. 22:3038-3044 (1994).
 RN [6]; RE0004040.
 RX
MEDLINE; 94344074.
 RA Reick M., Robertson R. W., Pasco D.
S., Fagan J. B.
 RT Down-regulation of nuclear aryl hydrocarbon
receptor DNA-binding and
 RT transactivation functions: requirement
for a labile or inducible factor
 RL Mol. Cell. Biol. 14:5653-5660
(1994).
 RN [7]; RE0006083.
 RX MEDLINE; 94359982.
 RA
Valge-Archer V. E., Osada H., Warren A. J., Forster A., Li J.,
Baer R.,
 RA Rabbitts T. H.
 RT The LIM protein RBTN2 and
the basic helix-loop-helix protein TAL1 are
 RT present in
a complex in erythroid cells
 RL Proc. Natl. Acad. Sci. USA
91:8617-8621 (1994).
 RN [8]; RE0004038.
 RX MEDLINE; 94038899.

RA Whitelaw M. L., Goettlicher M., Gustafsson J. A., Poelinger
L.
 RT Definition of a novel ligand binding domain of a nuclear
bHLH receptor:
 RT co-localization of ligand and hsp90 binding
activities within the regulable
 RT inactivation domain of
the dioxin receptor
 RL EMBO J. 12:4169-4179 (1993).
 RN
[9]; RE0004035.
 RX MEDLINE; 92163103.
 RA Aplan P. D.,
Lombardi D. P., Reaman G. H., Sather H. N., Hammond G. D.,

RA Kirsch I. R.
 RT Involvement of the putative hematopoitic
transcription factor SCL in T-cell
 RT acute lymphoblastic
leukemia
 RL Blood 79:1327-1333 (1992).
 RN [10]; RE0004043.

RX MEDLINE; 92390411.
 RA Burbach K. M., Poland A., Bradfield
C. A.
 RT Cloning of the Ah-receptor cDNA reveals a distinctive-ligand-activated

RT transcription factor
 RL Proc. Natl. Acad. Sci. USA 89:8185-8189
(1992).
 RN [11]; RE0001629.
 RX MEDLINE; 91246170.

RA Hsu H.-L., Cheng J.-T., Chen Q., Baer R.
 RT Enhancer-binding
activity of the tal-1 oncoprotein in association with the

RT E47/E12 helix-loop-helix proteins
 RL Mol. Cell. Biol. 11:3037-3042
(1991).
 RN [12]; RE0004029.
 RX MEDLINE; 90151616.

RA Chen Q., Cheng J. T., Tsai L. H., Schneider N., Buchanan G.,
Carroll A.,
 RA Crist W., Ozanne B., Siciliano M. J., Baer
R.
 RT The tal gene undergoes chromosome translocation in T
cell leukemia and
 RT potentially encodes a helix-loop-helix
protein
 RL EMBO J. 9:415-424 (1990).
 RN [13]; RE0004030.

RX MEDLINE; 91061750.
 RA Aplan P. D., Begley C. G., Bertness
V., Nussmeier M., Ezquerra A., Coligan
 RA J., Kirsch I. R.

RT The SCL gene is formed from a transcriptionally complex locus

RL Mol. Cell. Biol. 10:6426-6435 (1990).
 RN [14]; RE0004031.

RX MEDLINE; 91037802.
 RA Chen Q., Yang C. Y. C., Tsan J. T.,
Xia Y., Ragab A. H., Peiper S. C.,
 RA Carroll A., Baer R.

RT Coding sequences of the tal-1 gene are disrupted by chromosome

RT translocation in human T cell leukemia
 RL J. Exp. Med.
172:1403-1408 (1990).
 RN [15]; RE0004036.
 RX MEDLINE;
91075236.
 RA Aplan P. D., Lombardi D. P., Ginsberg A. M.,
Cossman J., Bertness V. L.,
 RA Kirsch I. R.
 RT Disruption
of the human SCL locus by 'illegitime' V(D)J recombinase activity

RL Science 250:1426-1429 (1990).
 RN [16]; RE0004037.
 RX
MEDLINE; 91006030.
 RA Brown L., Cheng J.-T., Chen Q., Siciliano
M. J., Christ W., Buchanan G.,
 RA Baer R.
 RT Site-specific
recombination of the tal-1 gene is a common occurence in
 RT
human T cell leukemia
 RL EMBO J. 9:3343-3351 (1990).
 RN
[17]; RE0004028.
 RX MEDLINE; 90099309.
 RA Begley C. G.,
Aplan P. D., Denning S. M., Haynes B. F., Waldmann T. A.,

RA Kirsch I. R.
 RT The gene SCL is expressed during early
hematopiesis and encodes a
 RT differentiation-related DNA-binding
motif
 RL Proc. Natl. Acad. Sci. USA 86:10128-10132 (1989).

RN [18]; RE0004034.
 RX MEDLINE; 89184561.
 RA Begley C.
G., Aplan P. D., Davey M. P., Nakahara K., Tchorz K., Kurtzberg

RA J., Hershfield M., Haynes B. F., Cohen D. I., Waldmann T. A.,
Kirsch I. R.
 RT Chromosomal translocation in a human leukemic
stem-cell line disrupts the
 RT T-cell antigen receptor delta-chain
diversity region and results in a
 RT previously unreported
fusion transcript
 RL Proc. Natl. Acad. Sci. USA 86:2031-2035
(1989).
 RN [19]; RE0004042.
 RX MEDLINE; 87230998.

RA Fujisawa-Sehara A., Sogawa K., Yamane M., Fuji-Kurijama Y.

RT Characterization of xenobiotic response elements upstream from
the
 RT drug-metabolizing cytochrome P450c gene: a similarity
to glucocorticoid
 RT regulatoty elements
 RL Nucleic Acids
Res. 15:4179-4191 (1987).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

259 genes, 259 accessions (Toggle view)

AccessionGeneTitleLinks
KIF9KIF9kinesin family member 9Source|GeneCards
FLNAFLNAfilamin A, alpha (actin binding protein 280)Source|GeneCards
KIAA0795KLHL18kelch-like 18 (Drosophila)Source|GeneCards
NXPH4NXPH4neurexophilin 4Source|GeneCards
TM4SF13TSPAN13tetraspanin 13Source|GeneCards
MSI1MSI1musashi homolog 1 (Drosophila)Source|GeneCards
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)Source|GeneCards
SULF1SULF1sulfatase 1Source|GeneCards
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2CSource|GeneCards
GABARAPL2GABARAPL2GABA(A) receptor-associated protein-like 2Source|GeneCards
NTF3NTF3neurotrophin 3Source|GeneCards
FHL3FHL3four and a half LIM domains 3Source|GeneCards
FGF7FGF7fibroblast growth factor 7 (keratinocyte growth factor)Source|GeneCards
NXPH3NXPH3neurexophilin 3Source|GeneCards
KERAKERAkeratocanSource|GeneCards
NHLH1NHLH1nescient helix loop helix 1Source|GeneCards
SHOX2SHOX2short stature homeobox 2Source|GeneCards
SAP30LSAP30LSin3A associated protein p30-likeSource|GeneCards
MLL5MLL5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)Source|GeneCards
ACVR1ACVR1activin A receptor, type ISource|GeneCards
TFDP2TFDP2transcription factor Dp-2 (E2F dimerization partner 2)Source|GeneCards
SOX12SOX12SRY (sex determining region Y)-box 12Source|GeneCards
SSB1SSB1SPRY domain-containing SOCS box protein SSB-1Source|GeneCards
ARHGAP22ARHGAP22Rho GTPase activating protein 22Source|GeneCards
JMJD2CJMJD2CJumonji domain containing 2CSource|GeneCards
AP3S1AP3S1adaptor-related protein complex 3, sigma 1 subunitSource|GeneCards
ARHGEF2ARHGEF2rho/rac guanine nucleotide exchange factor (GEF) 2Source|GeneCards
DERP6DERP6S-phase 2 proteinSource|GeneCards
CBFA2T1RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)Source|GeneCards
HRMT1L3HRMT1L3HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae)Source|GeneCards
HRKHRKharakiri, BCL2 interacting protein (contains only BH3 domain)Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
RAB27ARAB27ARAB27A, member RAS oncogene familySource|GeneCards
MGC48332MARCH3membrane-associated ring finger (C3HC4) 3Source|GeneCards
CHRNGCHRNGcholinergic receptor, nicotinic, gamma polypeptideSource|GeneCards
SLNSLNsarcolipinSource|GeneCards
SCN5ASCN5Asodium channel, voltage-gated, type V, alpha (long QT syndrome 3)Source|GeneCards
COLMGLDNgliomedinSource|GeneCards
PMF1PMF1polyamine-modulated factor 1Source|GeneCards
HOXC12HOXC12homeo box C12Source|GeneCards
MYCL2MYCL2v-myc myelocytomatosis viral oncogene homolog 2 (avian)Source|GeneCards
MKRN4MKRN4makorin, ring finger protein, 4Source|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
JADE1PHF17PHD finger protein 17Source|GeneCards
FBXW11FBXW11F-box and WD-40 domain protein 11Source|GeneCards
DUSP10DUSP10dual specificity phosphatase 10Source|GeneCards
OGTOGTO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)Source|GeneCards
LAF4LAF4lymphoid nuclear protein related to AF4Source|GeneCards
NEUROD2NEUROD2neurogenic differentiation 2Source|GeneCards
GJB2GJB2gap junction protein, beta 2, 26kDa (connexin 26)Source|GeneCards
KENAEKENAEKenaeSource|GeneCards
KIRREL2KIRREL2kin of IRRE like 2 (Drosophila)Source|GeneCards
SCN1BSCN1Bsodium channel, voltage-gated, type I, betaSource|GeneCards
C1QTNF4C1QTNF4C1q and tumor necrosis factor related protein 4Source|GeneCards
PDLIM4PDLIM4PDZ and LIM domain 4Source|GeneCards
FLJ44313FLJ44313FLJ44313 proteinSource|GeneCards
TPH2TPH2tryptophan hydroxylase 2Source|GeneCards
ARL4AARL4ADP-ribosylation factor-like 4Source|GeneCards
SIAT7ESIAT7Esialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) ESource|GeneCards
FAPFAPfibroblast activation protein, alphaSource|GeneCards
KIAA0922KIAA0922KIAA0922 proteinSource|GeneCards
NPR2NPR2natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)Source|GeneCards
C1ORF6UBQLN4ubiquilin 4Source|GeneCards
BAT5BAT5HLA-B associated transcript 5Source|GeneCards
STARD13STARD13START domain containing 13Source|GeneCards
LTBP1LTBP1latent transforming growth factor beta binding protein 1Source|GeneCards
TAFA1TAFA1TAFA1 proteinSource|GeneCards
SSH2SSH2slingshot 2Source|GeneCards
TAC1TAC1tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)Source|GeneCards
PCDH1PCDH1protocadherin 1 (cadherin-like 1)Source|GeneCards
FLJ33790FLJ33790hypothetical protein FLJ33790Source|GeneCards
PHOX2BPHOX2Bpaired-like homeobox 2bSource|GeneCards
EYA3EYA3eyes absent homolog 3 (Drosophila)Source|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
HECTD1HECTD1HECT domain containing 1Source|GeneCards
PBXIP1PBXIP1pre-B-cell leukemia transcription factor interacting protein 1Source|GeneCards
SH3KBP1SH3KBP1SH3-domain kinase binding protein 1Source|GeneCards
DLL4DLL4delta-like 4 (Drosophila)Source|GeneCards
TP53INP2TP53INP2tumor protein p53 inducible nuclear protein 2Source|GeneCards
KIBRAKIBRAKIBRA proteinSource|GeneCards
TGFB3TGFB3transforming growth factor, beta 3Source|GeneCards
MBD6MBD6methyl-CpG binding domain protein 6Source|GeneCards
MRPL11MRPL11mitochondrial ribosomal protein L11Source|GeneCards
SREB3GPR173G-protein coupled receptor 173Source|GeneCards
PABPC5PABPC5poly(A) binding protein, cytoplasmic 5Source|GeneCards
YT521YT521splicing factor YT521-BSource|GeneCards
SIX6SIX6sine oculis homeobox homolog 6 (Drosophila)Source|GeneCards
EHD4EHD4EH-domain containing 4Source|GeneCards
TP73LTP73Ltumor protein p73-likeSource|GeneCards
HOXA1HOXA1homeo box A1Source|GeneCards
ATOH7ATOH7atonal homolog 7 (Drosophila)Source|GeneCards
NPAS2NPAS2neuronal PAS domain protein 2Source|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
MGC14376MGC14376hypothetical protein MGC14376Source|GeneCards
B3GALT2B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2Source|GeneCards
182-FIP182-FIP82-kD FMRP Interacting ProteinSource|GeneCards
NAV3NAV3neuron navigator 3Source|GeneCards
EPLINEPLINepithelial protein lost in neoplasm betaSource|GeneCards
NKD1NKD1naked cuticle homolog 1 (Drosophila)Source|GeneCards
ITGA8ITGA8integrin, alpha 8Source|GeneCards
ARPC1AARPC1Aactin related protein 2/3 complex, subunit 1A, 41kDaSource|GeneCards
KCNJ2KCNJ2potassium inwardly-rectifying channel, subfamily J, member 2Source|GeneCards
RHOBTB1RHOBTB1Rho-related BTB domain containing 1Source|GeneCards
INHBEINHBEactivin beta ESource|GeneCards
CDC42EP4CDC42EP4CDC42 effector protein (Rho GTPase binding) 4Source|GeneCards
SIM1SIM1single-minded homolog 1 (Drosophila)Source|GeneCards
E2IG4LRRC54leucine rich repeat containing 54Source|GeneCards
DKFZP547K1113DKFZP547K1113hypothetical protein DKFZp547K1113Source|GeneCards
FLJ32384HEXIM2hexamthylene bis-acetamide inducible 2Source|GeneCards
KIAA0528KIAA0528KIAA0528 gene productSource|GeneCards
PHEXPHEXphosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets)Source|GeneCards
LOC389119LOC389119similar to RIKEN cDNA 6530418L21Source|GeneCards
TRIM3TRIM3tripartite motif-containing 3Source|GeneCards
KIAA0746KIAA0746KIAA0746 proteinSource|GeneCards
GTDC1GTDC1glycosyltransferase-like domain containing 1Source|GeneCards
PRG4PRG4proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)Source|GeneCards
SYNPRSYNPRsynaptoporinSource|GeneCards
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)Source|GeneCards
KCNQ1DNKCNQ1DNKCNQ1 downstream neighborSource|GeneCards
DKFZP434N1817C3ORF20Chromosome 3 open reading frame 20Source|GeneCards
PNMA1PNMA1paraneoplastic antigen MA1Source|GeneCards
DSCR1L1DSCR1L1Down syndrome critical region gene 1-like 1Source|GeneCards
FOXP2FOXP2forkhead box P2Source|GeneCards
DDIT3DDIT3DNA-damage-inducible transcript 3Source|GeneCards
WNT6WNT6wingless-type MMTV integration site family, member 6Source|GeneCards
FLJ33069TMEM71transmembrane protein 71Source|GeneCards
DAPK1DAPK1death-associated protein kinase 1Source|GeneCards
ZNF238ZNF238zinc finger protein 238Source|GeneCards
LOC112885LOC112885hypothetical protein BC012187Source|GeneCards
ELMO1ELMO1engulfment and cell motility 1 (ced-12 homolog, C. elegans)Source|GeneCards
CPNE1CPNE1RNA binding motif protein 12Source|GeneCards
ABCD2ABCD2ATP-binding cassette, sub-family D (ALD), member 2Source|GeneCards
NUMBLNUMBLnumb homolog (Drosophila)-likeSource|GeneCards
ANGPTL1ANGPTL1angiopoietin-like 1Source|GeneCards
HCKHCKhemopoietic cell kinaseSource|GeneCards
MTAC2D1MTAC2D1membrane targeting (tandem) C2 domain containing 1Source|GeneCards
GFI1GFI1growth factor independent 1Source|GeneCards
OR10J1OR10J1olfactory receptor, family 10, subfamily J, member 1Source|GeneCards
RAG2RAG2recombination activating gene 2Source|GeneCards
NEUROD6NEUROD6neurogenic differentiation 6Source|GeneCards
ELL2ELL2elongation factor, RNA polymerase II, 2Source|GeneCards
EIF3S10EIF3S10eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDaSource|GeneCards
FLJ43855FLJ43855similar to sodium- and chloride-dependent creatine transporterSource|GeneCards
PRKCBP1PRKCBP1protein kinase C binding protein 1Source|GeneCards
RNF133RNF133ring finger protein 133Source|GeneCards
LOC56901LOC56901NADH:ubiquinone oxidoreductase MLRQ subunit homologSource|GeneCards
STAG1STAG1Stromal antigen 1Source|GeneCards
TFAP2BL1TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta)Source|GeneCards
ICT1ICT1immature colon carcinoma transcript 1Source|GeneCards
LRRN1LRRN1leucine rich repeat neuronal 1Source|GeneCards
TTNTTNtitinSource|GeneCards
KIAA1001KIAA1001Arylsulfatase GSource|GeneCards
C7ORF33C7ORF33chromosome 7 open reading frame 33Source|GeneCards
PCDH12PCDH12protocadherin 12Source|GeneCards
ASB4ASB4ankyrin repeat and SOCS box-containing 4Source|GeneCards
HMP19HMP19HMP19 proteinSource|GeneCards
SEC15L1SEC15L1SEC15-like 1 (S. cerevisiae)Source|GeneCards
MPRP-1OMA1OMA1 homolog, zinc metallopeptidase (S. cerevisiae)Source|GeneCards
LPHN2LPHN2latrophilin 2Source|GeneCards
SEMA6DSEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6DSource|GeneCards
DARSDARSaspartyl-tRNA synthetaseSource|GeneCards
THRAP1THRAP1Thyroid hormone receptor associated protein 1Source|GeneCards
ARRDC3ARRDC3arrestin domain containing 3Source|GeneCards
OSMOSMoncostatin MSource|GeneCards
FLJ23751ACPL2acid phosphatase-like 2Source|GeneCards
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)Source|GeneCards
STC2STC2stanniocalcin 2Source|GeneCards
ZADH2ZADH2zinc binding alcohol dehydrogenase, domain containing 2Source|GeneCards
CDK11CDC2L6cell division cycle 2-like 6 (CDK8-like)Source|GeneCards
TJP4TJP4tight junction protein 4 (peripheral)Source|GeneCards
LRRN5LRRN5leucine rich repeat neuronal 5Source|GeneCards
GRID2GRID2glutamate receptor, ionotropic, delta 2Source|GeneCards
MGC34646MGC34646hypothetical protein MGC34646Source|GeneCards
CHST9CHST9carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9Source|GeneCards
HES6HES6hairy and enhancer of split 6 (Drosophila)Source|GeneCards
MAP1AMAP1Amicrotubule-associated protein 1ASource|GeneCards
CPECPEcarboxypeptidase ESource|GeneCards
STAG2STAG2stromal antigen 2Source|GeneCards
GKGKGlycerol kinaseSource|GeneCards
FMNL3FMNL3formin-like 3Source|GeneCards
MAPBPIPMAPBPIPmitogen-activated protein-binding protein-interacting proteinSource|GeneCards
ALDH1A1ALDH1A1aldehyde dehydrogenase 1 family, member A1Source|GeneCards
PHACTR3PHACTR3Phosphatase and actin regulator 3Source|GeneCards
GFRA3GFRA3GDNF family receptor alpha 3Source|GeneCards
RAB30RAB30RAB30, member RAS oncogene familySource|GeneCards
FLJ10159FLJ10159hypothetical protein FLJ10159Source|GeneCards
SRPULSRPX2sushi-repeat-containing protein, X-linked 2Source|GeneCards
HTR7HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)Source|GeneCards
ELF4ELF4E74-like factor 4 (ets domain transcription factor)Source|GeneCards
REPS2REPS2RALBP1 associated Eps domain containing 2Source|GeneCards
ONECUT1ONECUT1one cut domain, family member 1Source|GeneCards
E2F7E2F7E2F transcription factor 7Source|GeneCards
DCXDCXdoublecortex; lissencephaly, X-linked (doublecortin)Source|GeneCards
MACF1MACF1microtubule-actin crosslinking factor 1Source|GeneCards
DDAH2DDAH2dimethylarginine dimethylaminohydrolase 2Source|GeneCards
ONECUT2ONECUT2one cut domain, family member 2Source|GeneCards
PDE1APDE1Aphosphodiesterase 1A, calmodulin-dependentSource|GeneCards
AMPHAMPHamphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)Source|GeneCards
HRMT1L6HRMT1L6HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae)Source|GeneCards
C5ORF11C5ORF11chromosome 5 open reading frame 11Source|GeneCards
RNF19RNF19ring finger protein 19Source|GeneCards
MARK1MARK1MAP/microtubule affinity-regulating kinase 1Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
GPD1GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)Source|GeneCards
GRM8GRM8glutamate receptor, metabotropic 8Source|GeneCards
LOC55565LOC55565hypothetical protein LOC55565Source|GeneCards
NDPNDPNorrie disease (pseudoglioma)Source|GeneCards
CD79BCD79BCD79B antigen (immunoglobulin-associated beta)Source|GeneCards
MAP7MAP7microtubule-associated protein 7Source|GeneCards
CDH23CDH23cadherin related 23Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
PDE4BPDE4Bphosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)Source|GeneCards
DTX2DTX2deltex homolog 2 (Drosophila)Source|GeneCards
SND1SND1staphylococcal nuclease domain containing 1Source|GeneCards
TCF12TCF12transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)Source|GeneCards
NR6A1NR6A1nuclear receptor subfamily 6, group A, member 1Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
CDH6CDH6cadherin 6, type 2, K-cadherin (fetal kidney)Source|GeneCards
SMAD3SMAD3SMAD, mothers against DPP homolog 3 (Drosophila)Source|GeneCards
SWAP70SWAP70SWAP-70 proteinSource|GeneCards
C20ORF179C20ORF179chromosome 20 open reading frame 179Source|GeneCards
GFRA1GFRA1GDNF family receptor alpha 1Source|GeneCards
PI15PI15protease inhibitor 15Source|GeneCards
SPATS1SPATS1spermatogenesis associated, serine-rich 1Source|GeneCards
SULT2A1SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1Source|GeneCards
FGF9FGF9fibroblast growth factor 9 (glia-activating factor)Source|GeneCards
FLJ10324FLJ10324hypothetical protein FLJ10324Source|GeneCards
SELMSELMselenoprotein SelMSource|GeneCards
MGC33993RNF182ring finger protein 182Source|GeneCards
MAFMAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)Source|GeneCards
MAP2MAP2microtubule-associated protein 2Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
MGC8974LRRC42leucine rich repeat containing 42Source|GeneCards
BRD4BRD4bromodomain containing 4Source|GeneCards
FLJ33817FLJ33817hypothetical protein FLJ33817Source|GeneCards
C17ORF28C17ORF28chromosome 17 open reading frame 28Source|GeneCards
LOC284018LOC284018hypothetical protein LOC284018Source|GeneCards
PDGFBPDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)Source|GeneCards
FBXO16FBXO16F-box only protein 16Source|GeneCards
PICALMPICALMphosphatidylinositol binding clathrin assembly proteinSource|GeneCards
TBDN100NARG1NMDA receptor regulated 1Source|GeneCards
TRIM37TRIM37tripartite motif-containing 37Source|GeneCards
RIOK3RIOK3RIO kinase 3 (yeast)Source|GeneCards
MEF2CMEF2CMADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)Source|GeneCards
STK3STK3serine/threonine kinase 3 (STE20 homolog, yeast)Source|GeneCards
HAAOHAAO3-hydroxyanthranilate 3,4-dioxygenaseSource|GeneCards
NHLH2NHLH2nescient helix loop helix 2Source|GeneCards
DULLARDDULLARDdullard homolog (Xenopus laevis)Source|GeneCards
IGSF4DIGSF4Dimmunoglobulin superfamily, member 4DSource|GeneCards
SCGNSCGNsecretagogin, EF-hand calcium binding proteinSource|GeneCards
NCKIPSDNCKIPSDNCK interacting protein with SH3 domainSource|GeneCards
ACLYACLYATP citrate lyaseSource|GeneCards
CBFA2T3CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 3Source|GeneCards
MBNL2MBNL2muscleblind-like 2 (Drosophila)Source|GeneCards
APG12LAPG12LAPG12 autophagy 12-like (S. cerevisiae)Source|GeneCards
SLC2A12SLC2A12solute carrier family 2 (facilitated glucose transporter), member 12Source|GeneCards
GNASGNASGNAS complex locusSource|GeneCards
FLJ14107FLJ14107hypothetical protein FLJ14107Source|GeneCards
ITGBL1ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)Source|GeneCards

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