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Gene set: V$XBP1_01 (C3:TFAC:0162)
Standard nameV$XBP1_01
Systematic nameC3:TFAC:0162
Brief descriptionGenes with 3'UTR containing motif NNGNTGACGTGKNNNWT which matches annotation for XBP1: X-box binding protein 1
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA XBP-1
 XX
 SY hXBP-1; TREB-5; XBP-1;
X-box binding protein 1.
 XX
 OS human, Homo sapiens

OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda;
mammalia;
 OC eutheria; primates
 XX
 XX
 CL C0008;
bZIP; 1.1.1.1.1.
 XX
 SZ 260 AA; 28.7 kDa (cDNA), 38 kDa
(SDS) [4]
 XX
 XX
 SC SwissProt #P17861
 XX
 FT
8 55 proline-rich region (9/48).
 FT 58 93 basic region (16/36).

FT 67 131 PF00170; bZIP.
 FT 67 131 SM00338; BRLZ.
 FT 97
132 leucine zipper (L6).
 FT 139 162 acidic region (7/24).

FT 173 183 glutamine-rich region (5/11).
 FT 194 216 serine-/threonine-rich
region (9/23).
 FT 220 257 glutamine-/proline-rich region (13/38).

XX
 SF conflicting data: A33,R34 is G33,Q34,A35 in [4]

XX
 CP ubiquitous [4]
 XX
 FF binds to the X-box elements
of class II MHC genes [2] [1] [3];
 FF different from RF-X;

XX
 IN T00122; c-Fos; mouse, Mus musculus.
 IN T00123; c-Fos;
human, Homo sapiens.
 IN T00124; c-Fos; rat, Rattus norvegicus.

IN T00125; c-Fos; chick, Gallus gallus.
 XX
 XX
 XX

XX
 RN [1]; RE0001619.
 RX MEDLINE; 91203859.
 RA Vilen
B. J., Cogswell J. P., Ting J. P.-Y.
 RT Stereospecific alignment
of the X and Y elements is required for major
 RT histocompatibility
complex class II DRA promoter function
 RL Mol. Cell. Biol.
11:2406-2415 (1991).
 RN [2]; RE0002482.
 RX MEDLINE; 91239557.

RA Ono S. J., Liou H.-C., Davidon R., Strominger J. L., Glimcher
L. H.
 RT Human X-box-binding protein 1 is required for the
transcription of a subset
 RT of human class II major histocompatibility
gene and forms a heterodimer
 RT with c-fos
 RL Proc. Natl.
Acad. Sci. USA 88:4309-4312 (1991).
 RN [3]; RE0002716.

RX MEDLINE; 90208323.
 RA Liou H.-C., Boothby M. R., Finn P.
W., Davidson R., Nabavi N., Zeleznik-Le
 RA N. J., Ting J.
P.-Y., Glimcher L. H.
 RT A new member of the leucine zipper
class of proteins that binds to the HLA
 RT DRalpha promoter

RL Science 247:1581-1584 (1990).
 RN [4]; RE0003157.
 RX
MEDLINE; 90316112.
 RA Yoshimura T., Fujisawa J.-I., Yoshida
M.
 RT Multiple cDNA clones encoding nuclear proteins that
bind to the
 RT tax-dependent enhancer of HTLV-1: all contain
a leucine zipper structure
 RT and basic amino acid domain

RL EMBO J. 9:2537-2542 (1990).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

137 genes, 137 accessions (Toggle view)

AccessionGeneTitleLinks
C6ORF209C6ORF209chromosome 6 open reading frame 209Source|GeneCards
SMAP-5YIPF5Yip1 domain family, member 5Source|GeneCards
SRP68SRP68signal recognition particle 68kDaSource|GeneCards
HOXB5HOXB5homeo box B5Source|GeneCards
RPL36ALRPL36ALribosomal protein L36a-likeSource|GeneCards
FLJ21616FLJ21616hypothetical protein FLJ21616Source|GeneCards
H17H17hypothetical protein H17Source|GeneCards
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)Source|GeneCards
PX19PX19px19-like proteinSource|GeneCards
EML1EML1echinoderm microtubule associated protein like 1Source|GeneCards
SULF1SULF1sulfatase 1Source|GeneCards
SEC61A1SEC61A1Sec61 alpha 1 subunit (S. cerevisiae)Source|GeneCards
MAP3K13MAP3K13mitogen-activated protein kinase kinase kinase 13Source|GeneCards
TRIM46TRIM46tripartite motif-containing 46Source|GeneCards
E2F3E2F3E2F transcription factor 3Source|GeneCards
GLAGLAgalactosidase, alphaSource|GeneCards
IL1RAPL1IL1RAPL1interleukin 1 receptor accessory protein-like 1Source|GeneCards
KDELR1KDELR1KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1Source|GeneCards
PIM1PIM1pim-1 oncogeneSource|GeneCards
CDC42CDC42cell division cycle 42 (GTP binding protein, 25kDa)Source|GeneCards
PPP2R3APPP2R3Aprotein phosphatase 2 (formerly 2A), regulatory subunit B'', alphaSource|GeneCards
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)Source|GeneCards
GOSR2GOSR2golgi SNAP receptor complex member 2Source|GeneCards
MAGEL2MAGEL2MAGE-like 2Source|GeneCards
EPB41EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)Source|GeneCards
PPP1R10PPP1R10protein phosphatase 1, regulatory subunit 10Source|GeneCards
C13ORF10C13ORF10chromosome 13 open reading frame 10Source|GeneCards
GYS1GYS1glycogen synthase 1 (muscle)Source|GeneCards
GLRA2GLRA2glycine receptor, alpha 2Source|GeneCards
TM4SF2TM4SF2transmembrane 4 superfamily member 2Source|GeneCards
IL10IL10interleukin 10Source|GeneCards
C9ORF84C9ORF84chromosome 9 open reading frame 84Source|GeneCards
RUVBL2RUVBL2RuvB-like 2 (E. coli)Source|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
GCS1GCS1glucosidase ISource|GeneCards
SFRS1SFRS1splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)Source|GeneCards
LOC152485LOC152485hypothetical protein LOC152485Source|GeneCards
DHDDSDHDDSdehydrodolichyl diphosphate synthaseSource|GeneCards
MRPS18BMRPS18Bmitochondrial ribosomal protein S18BSource|GeneCards
RNPC2RNPC2RNA-binding region (RNP1, RRM) containing 2Source|GeneCards
RAB1ARAB1ARAB1A, member RAS oncogene familySource|GeneCards
DNM3DNM3dynamin 3Source|GeneCards
PRRX1PRRX1paired related homeobox 1Source|GeneCards
RAB24RAB24RAB24, member RAS oncogene familySource|GeneCards
CCND1CCND1cyclin D1 (PRAD1: parathyroid adenomatosis 1)Source|GeneCards
MORF4L2MORF4L2mortality factor 4 like 2Source|GeneCards
PAX1PAX1paired box gene 1Source|GeneCards
SLC30A5SLC30A5solute carrier family 30 (zinc transporter), member 5Source|GeneCards
PLEKHF1PLEKHF1pleckstrin homology domain containing, family F (with FYVE domain) member 1Source|GeneCards
SEC24DSEC24DSEC24 related gene family, member D (S. cerevisiae)Source|GeneCards
JADE1PHF17PHD finger protein 17Source|GeneCards
TYRO3TYRO3TYRO3 protein tyrosine kinaseSource|GeneCards
FLJ45187FLJ45187FLJ45187 proteinSource|GeneCards
ABTB2ABTB2ankyrin repeat and BTB (POZ) domain containing 2Source|GeneCards
ARL1ARL1ADP-ribosylation factor-like 1Source|GeneCards
CITED1CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1Source|GeneCards
RNF29TRIM55tripartite motif-containing 55Source|GeneCards
WFIKKNRPWFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2Source|GeneCards
ARMETARMETarginine-rich, mutated in early stage tumorsSource|GeneCards
GTF2A1GTF2A1general transcription factor IIA, 1, 19/37kDaSource|GeneCards
NEUROD2NEUROD2neurogenic differentiation 2Source|GeneCards
FLJ20259FLJ20259FLJ20259 proteinSource|GeneCards
DUSP7DUSP7dual specificity phosphatase 7Source|GeneCards
PCYT1BPCYT1Bphosphate cytidylyltransferase 1, choline, beta isoformSource|GeneCards
TCF4TCF4Transcription factor 4Source|GeneCards
ARFGAP3ARFGAP3ADP-ribosylation factor GTPase activating protein 3Source|GeneCards
RAB25RAB25RAB25, member RAS oncogene familySource|GeneCards
SEMA3BSEMA3Bsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3BSource|GeneCards
APLNAPLNapelinSource|GeneCards
GALEGALEgalactose-4-epimerase, UDP-Source|GeneCards
RBP5RBP5Retinol binding protein 5, cellularSource|GeneCards
ITCHITCHitchy homolog E3 ubiquitin protein ligase (mouse)Source|GeneCards
CASKCASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)Source|GeneCards
PURAPURApurine-rich element binding protein ASource|GeneCards
HCRTR2HCRTR2hypocretin (orexin) receptor 2Source|GeneCards
EPC1EPC1enhancer of polycomb homolog 1, (Drosophila)Source|GeneCards
DNAJB4DNAJB4DnaJ (Hsp40) homolog, subfamily B, member 4Source|GeneCards
RGS1RGS1regulator of G-protein signalling 1Source|GeneCards
FLJ44635FLJ44635TPT1-like proteinSource|GeneCards
RHEBL1RHEBL1Ras homolog enriched in brain like 1Source|GeneCards
ERP70PDIA4protein disulfide isomerase family A, member 4Source|GeneCards
ASXL2ASXL2additional sex combs like 2 (Drosophila)Source|GeneCards
C2ORF11C2ORF11chromosome 2 open reading frame 11Source|GeneCards
PRDX4PRDX4peroxiredoxin 4Source|GeneCards
KIAA0460KIAA0460KIAA0460 proteinSource|GeneCards
ARMCX3ARMCX3armadillo repeat containing, X-linked 3Source|GeneCards
ELAVL2ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)Source|GeneCards
VDPVDPvesicle docking protein p115Source|GeneCards
KISS1KISS1KiSS-1 metastasis-suppressorSource|GeneCards
UBE2BUBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)Source|GeneCards
GRIA3GRIA3glutamate receptor, ionotrophic, AMPA 3Source|GeneCards
SND1SND1staphylococcal nuclease domain containing 1Source|GeneCards
SOX21SOX21SRY (sex determining region Y)-box 21Source|GeneCards
TP53INP2TP53INP2tumor protein p53 inducible nuclear protein 2Source|GeneCards
OSBPOSBPoxysterol binding proteinSource|GeneCards
KIAA1190ZNF651zinc finger protein 651Source|GeneCards
C10ORF74C10ORF74chromosome 10 open reading frame 74Source|GeneCards
NKX2-2NKX2-2NK2 transcription factor related, locus 2 (Drosophila)Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
KIF12KIF12kinesin family member 12Source|GeneCards
ELF1ELF1E74-like factor 1 (ets domain transcription factor)Source|GeneCards
CADPSCADPSCa2+-dependent activator protein for secretionSource|GeneCards
FLJ30296PTCHD1Patched domain containing 1Source|GeneCards
NPAS2NPAS2neuronal PAS domain protein 2Source|GeneCards
MGC17299MGC17299hypothetical protein MGC17299Source|GeneCards
TRIB2TRIB2tribbles homolog 2 (Drosophila)Source|GeneCards
MMP14MMP14matrix metalloproteinase 14 (membrane-inserted)Source|GeneCards
PRO1855PRO1855hypothetical protein PRO1855Source|GeneCards
SIK2SNF1LK2SNF1-like kinase 2Source|GeneCards
SNTB2SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)Source|GeneCards
GARSGARSGlycyl-tRNA synthetaseSource|GeneCards
SP1SP1Sp1 transcription factorSource|GeneCards
ARMCX2ARMCX2armadillo repeat containing, X-linked 2Source|GeneCards
TRPC4APTRPC4APtransient receptor potential cation channel, subfamily C, member 4 associated proteinSource|GeneCards
SYT3SYT3synaptotagmin IIISource|GeneCards
C18ORF23C18ORF23chromosome 18 open reading frame 23Source|GeneCards
HNRPH2HNRPH2heterogeneous nuclear ribonucleoprotein H2 (H')Source|GeneCards
LHX5LHX5LIM homeobox 5Source|GeneCards
C17ORF28C17ORF28chromosome 17 open reading frame 28Source|GeneCards
FKBP14FKBP14FK506 binding protein 14, 22 kDaSource|GeneCards
STAT3STAT3signal transducer and activator of transcription 3 (acute-phase response factor)Source|GeneCards
TM9SF1TM9SF1transmembrane 9 superfamily member 1Source|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
RAB6IP1RAB6IP1RAB6 interacting protein 1Source|GeneCards
IRS4IRS4insulin receptor substrate 4Source|GeneCards
NMNAT2NMNAT2nicotinamide nucleotide adenylyltransferase 2Source|GeneCards
XPNPEP1XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, solubleSource|GeneCards
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3Source|GeneCards
SRPRSRPRsignal recognition particle receptor ('docking protein')Source|GeneCards
HBP1HBP1HMG-box transcription factor 1Source|GeneCards
GPR3GPR3G protein-coupled receptor 3Source|GeneCards
MGAT2MGAT2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferaseSource|GeneCards
SFRS5SFRS5splicing factor, arginine/serine-rich 5Source|GeneCards
CLSTN3CLSTN3calsyntenin 3Source|GeneCards
LOC51334LOC51334mesenchymal stem cell protein DSC54Source|GeneCards
KRTCAP2KRTCAP2keratinocyte associated protein 2Source|GeneCards
FLJ10871FLJ10871hypothetical protein FLJ10871Source|GeneCards

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