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Gene set: STTTCRNTTT_V$IRF_Q6 (C3:REPM:0141)
Standard nameSTTTCRNTTT_V$IRF_Q6
Systematic nameC3:REPM:0141
Brief descriptionGenes with 3'UTR containing motif STTTCRNTTT. Motif does not match any known transcription factor
CategoryC3: Motif
Sub-categoryREPM: Representative motifs
Full description or Abstract

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XX
 XX
 XX
 FA IRF-10
 XX
 SY IRF10; Interferon
regulatory factor 10.
 XX
 OS chick, Gallus gallus
 OC
eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes;

OC neognathae; galliformes; phasianidae
 XX
 XX
 CL C0022;
trp.
 XX
 SZ 416 AA; 47.6 kDa (calc), 46 kDa (SDS) [1]

XX
 XX
 SC translated from EMBL #AF380350
 XX
 FT
3 116 PF00605; IRF.
 FT 3 116 SM00348; IRF.
 FT 6 116 DNA-binding
domain (DBD) [1].
 FT 203 379 interaction domain (IAD) [1].

XX
 SF amino acid identity to mammalian and avian paralogs:
about 43% to IRF-4
 SF , 36% to IRF-8 , less than 30% to
 SF other IRFs [1]
 XX

FF expression inducible by interferons (IFN1 and IFNgamma: primary

FF fibroblasts) and concanavalin A (splenic culture) and dependent
on protein
 FF synthesis (blockable by cycloheximide) [1];

FF seems mainly located in the nucleus (when expressed in chicken
embryonic
 FF fibroblasts) [1];
 FF expression was maintained
for several weeks in fibroblast an DT40 line
 FF (contrast
to IRF-1 and IRF-8) [1]: modulates expression of IFN-induced

FF genes: increase of GBP  expression and decrease of
OAS 
 FF expression [1];
 FF contributes to the
regulation of MHC I expression [1];
 FF expressed in a variety
of hematopoietic transformed cell lines with very
 FF high
level in v-rel-transformed cell lines [1];
 FF expression inducible
by v-Rel and to a lesser degree by c-Rel (in lymphoid
 FF cells)
[1];
 FF IRF-4 also induces expression which is enhanced by
v-Rel [1];
 XX
 XX
 XX
 XX
 RN [1]; RE0017882.

RX MEDLINE; 21993151.
 RA Nehyba J., Hrdlickova R., Burnside
J., Bose HR J. r.
 RT A novel interferon regulatory factor
(IRF), IRF-10, has a unique role in
 RT immune defense and
is induced by the v-Rel oncoprotein
 RL Mol. Cell. Biol. 22:3942-3957
(2002).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

194 genes, 194 accessions (Toggle view)

AccessionGeneTitleLinks
CASP1CASP1caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)Source|GeneCards
TCEB3BTCEB3Btranscription elongation factor B polypeptide 3B (elongin A2)Source|GeneCards
WNT5AWNT5Awingless-type MMTV integration site family, member 5ASource|GeneCards
CDK6CDK6cyclin-dependent kinase 6Source|GeneCards
TCF8TCF8transcription factor 8 (represses interleukin 2 expression)Source|GeneCards
HDAC4HDAC4histone deacetylase 4Source|GeneCards
EVLEVLEnah/Vasp-likeSource|GeneCards
MEIS1MEIS1Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)Source|GeneCards
RAPGEF6RAPGEF6Rap guanine nucleotide exchange factor (GEF) 6Source|GeneCards
LGALS3BPLGALS3BPlectin, galactoside-binding, soluble, 3 binding proteinSource|GeneCards
E2F3E2F3E2F transcription factor 3Source|GeneCards
ARHGAP5ARHGAP5Rho GTPase activating protein 5Source|GeneCards
NFATC1NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1Source|GeneCards
M11S1M11S1membrane component, chromosome 11, surface marker 1Source|GeneCards
SCA1ATXN1ataxin 1Source|GeneCards
FLT3LGFLT3LGfms-related tyrosine kinase 3 ligandSource|GeneCards
PITX2PITX2paired-like homeodomain transcription factor 2Source|GeneCards
TFDP2TFDP2transcription factor Dp-2 (E2F dimerization partner 2)Source|GeneCards
SSB1SSB1SPRY domain-containing SOCS box protein SSB-1Source|GeneCards
IFIT2IFIT2interferon-induced protein with tetratricopeptide repeats 2Source|GeneCards
PPP1R10PPP1R10protein phosphatase 1, regulatory subunit 10Source|GeneCards
MSCMSCmusculin (activated B-cell factor-1)Source|GeneCards
RNF31RNF31ring finger protein 31Source|GeneCards
BCL2L1BCL2L1BCL2-like 1Source|GeneCards
CBX4CBX4chromobox homolog 4 (Pc class homolog, Drosophila)Source|GeneCards
NR3C2NR3C2nuclear receptor subfamily 3, group C, member 2Source|GeneCards
MAB21L1MAB21L1mab-21-like 1 (C. elegans)Source|GeneCards
MRPS18BMRPS18Bmitochondrial ribosomal protein S18BSource|GeneCards
CIG5RSAD2radical S-adenosyl methionine domain containing 2Source|GeneCards
ETV6ETV6ets variant gene 6 (TEL oncogene)Source|GeneCards
CXCL10CXCL10chemokine (C-X-C motif) ligand 10Source|GeneCards
CCND1CCND1cyclin D1 (PRAD1: parathyroid adenomatosis 1)Source|GeneCards
FLJ46020FLJ46020FLJ46020 proteinSource|GeneCards
SLC15A3SLC15A3solute carrier family 15, member 3Source|GeneCards
HIP1RHIP1Rhuntingtin interacting protein-1-relatedSource|GeneCards
EGFL6EGFL6EGF-like-domain, multiple 6Source|GeneCards
BST2BST2bone marrow stromal cell antigen 2Source|GeneCards
FLJ40224PRR10proline rich 10Source|GeneCards
FMR1FMR1fragile X mental retardation 1Source|GeneCards
PBEF1PBEF1pre-B-cell colony enhancing factor 1Source|GeneCards
PSMB8PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7)Source|GeneCards
MSFPRG4proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)Source|GeneCards
TRPM3TRPM3transient receptor potential cation channel, subfamily M, member 3Source|GeneCards
HPCAL1HPCAL1hippocalcin-like 1Source|GeneCards
CLDN3CLDN3claudin 3Source|GeneCards
SFMBT1SFMBT1Scm-like with four mbt domains 1Source|GeneCards
FLJ45803FLJ45803FLJ45803 proteinSource|GeneCards
NPR3NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)Source|GeneCards
BAT5BAT5HLA-B associated transcript 5Source|GeneCards
TAPBPLTAPBPLTAP binding protein-likeSource|GeneCards
CASP7CASP7caspase 7, apoptosis-related cysteine proteaseSource|GeneCards
MAP3K11MAP3K11mitogen-activated protein kinase kinase kinase 11Source|GeneCards
MSX1MSX1msh homeo box homolog 1 (Drosophila)Source|GeneCards
OSR2OSR2odd-skipped-related 2A proteinSource|GeneCards
UBE1LUBE1Lubiquitin-activating enzyme E1-likeSource|GeneCards
NT5C3NT5C35'-nucleotidase, cytosolic IIISource|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
SORBS1SORBS1sorbin and SH3 domain containing 1Source|GeneCards
ECM2ECM2extracellular matrix protein 2, female organ and adipocyte specificSource|GeneCards
GSCGSCgoosecoidSource|GeneCards
KCNE4KCNE4potassium voltage-gated channel, Isk-related family, member 4Source|GeneCards
TCIRG1TCIRG1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a isoform 3Source|GeneCards
ZBP1ZBP1Z-DNA binding protein 1Source|GeneCards
EPSTI1EPSTI1epithelial stromal interaction 1 (breast)Source|GeneCards
G1P2G1P2interferon, alpha-inducible protein (clone IFI-15K)Source|GeneCards
CRK7CRK7CDC2-related protein kinase 7Source|GeneCards
NYREN18NYREN18NEDD8 ultimate buster-1Source|GeneCards
HIAN7HIAN7immune associated nucleotideSource|GeneCards
INDOINDOindoleamine-pyrrole 2,3 dioxygenaseSource|GeneCards
ESR1ESR1estrogen receptor 1Source|GeneCards
SYNE2SYNE2spectrin repeat containing, nuclear envelope 2Source|GeneCards
NAV3NAV3neuron navigator 3Source|GeneCards
SFRS12SFRS12splicing factor, arginine/serine-rich 12Source|GeneCards
IL27IL27Interleukin 27Source|GeneCards
CHCHD1CHCHD1Coiled-coil-helix-coiled-coil-helix domain containing 1Source|GeneCards
NRG1NRG1neuregulin 1Source|GeneCards
DLX4DLX4distal-less homeobox 4Source|GeneCards
PGM5PGM5phosphoglucomutase 5Source|GeneCards
ELK4ELK4ELK4, ETS-domain protein (SRF accessory protein 1)Source|GeneCards
MOV10MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)Source|GeneCards
PRKD2PRKD2protein kinase D2Source|GeneCards
SOX5SOX5SRY (sex determining region Y)-box 5Source|GeneCards
IFIT4IFIT3interferon-induced protein with tetratricopeptide repeats 3Source|GeneCards
FLJ11286FLJ11286hypothetical protein FLJ11286Source|GeneCards
VAMP5VAMP5vesicle-associated membrane protein 5 (myobrevin)Source|GeneCards
USP18USP18ubiquitin specific protease 18Source|GeneCards
HOXB6HOXB6homeo box B6Source|GeneCards
FLJ39827FLJ39827hypothetical protein FLJ39827Source|GeneCards
DDX58DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 58Source|GeneCards
C20ORF18C20ORF18chromosome 20 open reading frame 18Source|GeneCards
MGAT4AMGAT4Amannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme ASource|GeneCards
GRAP2GRAP2GRB2-related adaptor protein 2Source|GeneCards
CCDC6CCDC6coiled-coil domain containing 6Source|GeneCards
MGC20410MGC20410hypothetical protein BC012330Source|GeneCards
DDR2DDR2discoidin domain receptor family, member 2Source|GeneCards
LRP2LRP2low density lipoprotein-related protein 2Source|GeneCards
CPT1ACPT1Acarnitine palmitoyltransferase 1A (liver)Source|GeneCards
PIGRPIGRpolymeric immunoglobulin receptorSource|GeneCards
NSE2FAM84Bfamily with sequence similarity 84, member BSource|GeneCards
ZNF503ZNF503zinc finger protein 503Source|GeneCards
TAPBPTAPBPTAP binding protein (tapasin)Source|GeneCards
PRKCL2PKN2protein kinase N2Source|GeneCards
PSME1PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)Source|GeneCards
PTK2PTK2PTK2 protein tyrosine kinase 2Source|GeneCards
KIRREL3KIRREL3kin of IRRE like 3 (Drosophila)Source|GeneCards
SFRS6SFRS6splicing factor, arginine/serine-rich 6Source|GeneCards
LGI1LGI1leucine-rich, glioma inactivated 1Source|GeneCards
TCTEL1TCTEL1t-complex-associated-testis-expressed 1-like 1Source|GeneCards
ZDHHC14ZDHHC14zinc finger, DHHC domain containing 14Source|GeneCards
RNF159PCGF5polycomb group ring finger 5Source|GeneCards
MHC2TAMHC2TAMHC class II transactivatorSource|GeneCards
NEDD4NEDD4neural precursor cell expressed, developmentally down-regulated 4Source|GeneCards
PIK3R3PIK3R3phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)Source|GeneCards
CD200RCD200R1CD200 receptor 1Source|GeneCards
ITGB7ITGB7integrin, beta 7Source|GeneCards
PSIP1PSIP1PC4 and SFRS1 interacting protein 1Source|GeneCards
FLJ33387FLJ33387hypothetical protein FLJ33387Source|GeneCards
KIAA0140FAM53Bfamily with sequence similarity 53, member BSource|GeneCards
SLC12A7SLC12A7solute carrier family 12 (potassium/chloride transporters), member 7Source|GeneCards
THRAP1THRAP1Thyroid hormone receptor associated protein 1Source|GeneCards
FLJ20477PIGVphosphatidylinositol glycan, class VSource|GeneCards
PHF15PHF15PHD finger protein 15Source|GeneCards
OSMOSMoncostatin MSource|GeneCards
GSH1GSH1GS homeobox 1Source|GeneCards
PSMB10PSMB10proteasome (prosome, macropain) subunit, beta type, 10Source|GeneCards
IL22RA1IL22RA1interleukin 22 receptor, alpha 1Source|GeneCards
PSME2PSME2proteasome (prosome, macropain) activator subunit 2 (PA28 beta)Source|GeneCards
COL4A1COL4A1collagen, type IV, alpha 1Source|GeneCards
PSMB9PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)Source|GeneCards
IL12RB1IL12RB1interleukin 12 receptor, beta 1Source|GeneCards
NCF1NCF1neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1)Source|GeneCards
KLHL13KLHL13kelch-like 13 (Drosophila)Source|GeneCards
SATB2SATB2SATB family member 2Source|GeneCards
CHGBCHGBchromogranin B (secretogranin 1)Source|GeneCards
ALDH1A1ALDH1A1aldehyde dehydrogenase 1 family, member A1Source|GeneCards
GATA6GATA6GATA binding protein 6Source|GeneCards
GSDMDC1GSDMDC1gasdermin domain containing 1Source|GeneCards
NFIXNFIXnuclear factor I/X (CCAAT-binding transcription factor)Source|GeneCards
TAP1TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)Source|GeneCards
C9ORF150C9ORF150chromosome 9 open reading frame 150Source|GeneCards
LRMPLRMPlymphoid-restricted membrane proteinSource|GeneCards
BBAPDTX3Ldeltex 3-like (Drosophila)Source|GeneCards
YWHAGYWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptideSource|GeneCards
CARD15CARD15caspase recruitment domain family, member 15Source|GeneCards
OTX1OTX1orthodenticle homolog 1 (Drosophila)Source|GeneCards
BCORBCORBCL6 co-repressorSource|GeneCards
VGLL4VGLL4vestigial like 4 (Drosophila)Source|GeneCards
HOXA13HOXA13homeo box A13Source|GeneCards
IL4IL4interleukin 4Source|GeneCards
HGFHGFhepatocyte growth factor (hepapoietin A; scatter factor)Source|GeneCards
USP44USP44ubiquitin specific protease 44Source|GeneCards
MLLT3MLLT3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3Source|GeneCards
COL4A2COL4A2collagen, type IV, alpha 2Source|GeneCards
SSA1TRIM21tripartite motif-containing 21Source|GeneCards
MXI1MXI1MAX interacting protein 1Source|GeneCards
SLC25A28SLC25A28solute carrier family 25, member 28Source|GeneCards
IL18BPIL18BPinterleukin 18 binding proteinSource|GeneCards
IFNB1IFNB1interferon, beta 1, fibroblastSource|GeneCards
TCF12TCF12transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)Source|GeneCards
UBDUBDubiquitin DSource|GeneCards
TNFSF13BTNFSF13Btumor necrosis factor (ligand) superfamily, member 13bSource|GeneCards
LGP2LGP2likely ortholog of mouse D11lgp2Source|GeneCards
IFI44IFI44interferon-induced protein 44Source|GeneCards
IGFBP5IGFBP5insulin-like growth factor binding protein 5Source|GeneCards
BALPARP9poly (ADP-ribose) polymerase family, member 9Source|GeneCards
ZNF366ZNF366zinc finger protein 366Source|GeneCards
B2MB2Mbeta-2-microglobulinSource|GeneCards
ADAM12ADAM12a disintegrin and metalloproteinase domain 12 (meltrin alpha)Source|GeneCards
USF1USF1upstream transcription factor 1Source|GeneCards
CITED2CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2Source|GeneCards
EDIL3EDIL3EGF-like repeats and discoidin I-like domains 3Source|GeneCards
LIFLIFleukemia inhibitory factor (cholinergic differentiation factor)Source|GeneCards
ASPAASPAaspartoacylase (aminoacylase 2, Canavan disease)Source|GeneCards
TCF15TCF15transcription factor 15 (basic helix-loop-helix)Source|GeneCards
CXORF1CXORF1chromosome X open reading frame 1Source|GeneCards
LSM6LSM6LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)Source|GeneCards
RPL23RPL23Ribosomal protein L23Source|GeneCards
BHLHB3BHLHB3basic helix-loop-helix domain containing, class B, 3Source|GeneCards
CXORF21CXORF21Chromosome X open reading frame 21Source|GeneCards
ARHGEF6ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6Source|GeneCards
DKFZP547A023CTTNBP2NLCTTNBP2 N-terminal likeSource|GeneCards
CDKN2CCDKN2Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Source|GeneCards
EIF5AEIF5Aeukaryotic translation initiation factor 5ASource|GeneCards
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)Source|GeneCards
PSMA5PSMA5proteasome (prosome, macropain) subunit, alpha type, 5Source|GeneCards
IL17RCIL17RCinterleukin 17 receptor CSource|GeneCards
ASXL1ASXL1additional sex combs like 1 (Drosophila)Source|GeneCards
PPARGC1APPARGC1Aperoxisome proliferative activated receptor, gamma, coactivator 1, alphaSource|GeneCards
HSXIAPAF1HSXIAPAF1XIAP associated factor-1Source|GeneCards
PLXNC1PLXNC1plexin C1Source|GeneCards
CREB1CREB1cAMP responsive element binding protein 1Source|GeneCards
PSMA3PSMA3proteasome (prosome, macropain) subunit, alpha type, 3Source|GeneCards
FLJ20321CASZ1castor homolog 1, zinc finger (Drosophila)Source|GeneCards
FEZLZNF312zinc finger protein 312Source|GeneCards

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