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Gene set: V$AR_03 (C3:TFAC:0433)
Standard nameV$AR_03
Systematic nameC3:TFAC:0433
Brief descriptionGenes with 3'UTR containing motif NNNNNNRGNACRNNGTGTTCTNNNNNN which matches annotation for AR: androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA AR
 XX
 SY androgen receptor; AR;
NR3C4; dihydrotestosterone receptor.
 XX
 OS rat, Rattus
norvegicus
 OC eukaryota; animalia; metazoa; chordata; vertebrata;
tetrapoda; mammalia;
 OC eutheria; rodentia; myomorpha; muridae;
murinae
 XX
 XX
 CL C0002; CC (rec); 2.1.1.3.1.
 XX

SZ 902 AA; 98.2 kDa (cDNA), 98.9 kDa (SDS)
 XX
 XX
 SC
SwissProt #P15207
 XX
 FT 6 445 PF02166; Androgen_recep.

FT 539 610 SM00399; ZnF_C4.
 FT 540 606 region C, DNA-binding
domain (DBD).
 FT 540 615 PF00105; zf-C4.
 FT 689 853 SM00430;
HOLI.
 FT 692 878 PF00104; hormone_rec.
 XX
 SF can form
multimeric complexes [3]
 XX
 FF regulates androgen-dependent
gene expression by binding to
 FF androgen-responsive elements
(ARE) [4];
 FF its DNA-binding domain can interact with leucine
zipper of AP1 to result in
 FF mutual transrepression [2].;

XX
 XX
 XX
 XX
 RN [1]; RE0002368.
 RX MEDLINE;
89017168.
 RA Chang C., Kokontis J., Liao S.
 RT Structural
analysis of complementary DNA and amino acid sequences of human

RT and rat androgen receptors
 RL Proc. Natl. Acad. Sci. USA
85:7211-7215 (1988).
 RN [2]; RE0023374.
 RX MEDLINE; 9211894.

RA Sato N., Sadar M. D., Bruchovsky N., Saatcioglu F., Rennie
P. S., Sato S.,
 RA Lange P. H., Gleave M. E.
 RT Androgenic
induction of prostate-specific antigen gene is repressed by

RT protein-protein interaction between the androgen receptor and
AP-1/c-Jun in
 RT the human prostate cancer cell line LNCaP.

RL J. Biol. Chem. 272:17485-17494 (1997).
 RN [3]; RE0010237.

RA Kasper S., Rennie P. S., Bruchovsky N., Sheppard P. C., Cheng
H., Lin L.,
 RA Shiu R. P. C., Snoek R., Matusik R. J.

RT Cooperative binding of androgen receptors to two DNA sequences
is required
 RT for androgen induction of the probasin gene

RL J. Biol. Chem. 269:31763-31769 (1994).
 RN [4]; RE0001011.

RX MEDLINE; 91139625.
 RA de Vos P., Claessens F., Winderickx
J., van Dijck P., Celis L., Peeters B.,
 RA Rombauts W., Heyns
W., Verhoeven G.
 RT Interaction of androgen response elements
with the DNA-binding domain of
 RT the rat androgen receptor
expressed in Escherichia coli
 RL J. Biol. Chem. 266:3439-3443
(1991).
 RN [5]; RE0003759.
 RX MEDLINE; 91309548.
 RA
Danzo B. J., Parrot J. A., Skinner M. K.
 RT Analysis of the
steroid binding domain of rat androgen-binding protein
 RL
Endocrinology 129:690-696 (1991).
 RN [6]; RE0001752.
 RX
MEDLINE; 91042631.
 RA Forman B. M., Samuels H. H.
 RT Interactions
among a subfamily of nuclear hormone receptors: the regulatory

RT zipper model
 RL Mol. Endocrinol. 4:1293-1301 (1990).

RN [7]; RE0002369.
 RX MEDLINE; 89098909.
 RA Tilley W.,
Marcelli M., Wilson J. D., McPhaul M. J.
 RT Characterization
and expression of a cDNA encoding the human androgen
 RT receptor

RL Proc. Natl. Acad. Sci. USA 86:327-331 (1989).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

60 genes, 60 accessions (Toggle view)

AccessionGeneTitleLinks
KLHL5KLHL5kelch-like 5 (Drosophila)Source|GeneCards
NRGNNRGNneurogranin (protein kinase C substrate, RC3)Source|GeneCards
PYGMPYGMphosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)Source|GeneCards
SLC9A1SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)Source|GeneCards
LOC113251LOC113251c-Mpl binding proteinSource|GeneCards
CCDC6CCDC6coiled-coil domain containing 6Source|GeneCards
ADCY6ADCY6adenylate cyclase 6Source|GeneCards
REREREREarginine-glutamic acid dipeptide (RE) repeatsSource|GeneCards
DNAJB4DNAJB4DnaJ (Hsp40) homolog, subfamily B, member 4Source|GeneCards
TENC1TENC1tensin like C1 domain-containing phosphataseSource|GeneCards
NCDNNCDNneurochondrinSource|GeneCards
BDNFBDNFbrain-derived neurotrophic factorSource|GeneCards
WNT9AWNT9Awingless-type MMTV integration site family, member 9ASource|GeneCards
RNF28TRIM63tripartite motif-containing 63Source|GeneCards
ITGA6ITGA6integrin, alpha 6Source|GeneCards
LOC253012LOC253012hypothetical protein LOC253012Source|GeneCards
BHC80PHF21APHD finger protein 21ASource|GeneCards
SMOXSMOXspermine oxidaseSource|GeneCards
NLKNLKnemo like kinaseSource|GeneCards
SDC1SDC1syndecan 1Source|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
USP54USP54ubiquitin specific protease 54Source|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
ZCCHC5ZCCHC5zinc finger, CCHC domain containing 5Source|GeneCards
FLJ10997ZNF654zinc finger protein 654Source|GeneCards
SMYD5SMYD5SMYD family member 5Source|GeneCards
KCNH5KCNH5potassium voltage-gated channel, subfamily H (eag-related), member 5Source|GeneCards
RAB1BRAB1BRAB1B, member RAS oncogene familySource|GeneCards
MGC41945MGC41945hypothetical protein MGC41945Source|GeneCards
AMY2AAMY2Aamylase, alpha 2A; pancreaticSource|GeneCards
FSTL5FSTL5follistatin-like 5Source|GeneCards
KIAA1632KIAA1632KIAA1632 proteinSource|GeneCards
PKD1-LIKEPKD1-LIKEpolycystic kidney disease 1-likeSource|GeneCards
CPEB4CPEB4cytoplasmic polyadenylation element binding protein 4Source|GeneCards
GSDMGSDM1gasdermin 1Source|GeneCards
BCL6BCL6B-cell CLL/lymphoma 6 (zinc finger protein 51)Source|GeneCards
SFRS12SFRS12splicing factor, arginine/serine-rich 12Source|GeneCards
DLX3DLX3distal-less homeo box 3Source|GeneCards
FLJ27255FLJ27255FLJ27255 proteinSource|GeneCards
KCNJ1KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1Source|GeneCards
BAI3BAI3brain-specific angiogenesis inhibitor 3Source|GeneCards
MAP4K5MAP4K5mitogen-activated protein kinase kinase kinase kinase 5Source|GeneCards
OTPOTPorthopedia homolog (Drosophila)Source|GeneCards
RCN1RCN1reticulocalbin 1, EF-hand calcium binding domainSource|GeneCards
CXCL14CXCL14chemokine (C-X-C motif) ligand 14Source|GeneCards
RBM24RBM24RNA binding motif protein 24Source|GeneCards
JPH1JPH1junctophilin 1Source|GeneCards
IHPK2IHPK2inositol hexaphosphate kinase 2Source|GeneCards
ELAVL4ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)Source|GeneCards
ZP3ZP3zona pellucida glycoprotein 3 (sperm receptor)Source|GeneCards
KHDRBS1KHDRBS1KH domain containing, RNA binding, signal transduction associated 1Source|GeneCards
RANBP9RANBP9RAN binding protein 9Source|GeneCards
ADNPADNPactivity-dependent neuroprotectorSource|GeneCards
NSD1NSD1nuclear receptor binding SET domain protein 1Source|GeneCards
SLC7A8SLC7A8solute carrier family 7 (cationic amino acid transporter, y+ system), member 8Source|GeneCards
KIAA1468KIAA1468KIAA1468 proteinSource|GeneCards
LOC148523LOC148523hypothetical protein BC017397Source|GeneCards
SCNN1ASCNN1Asodium channel, nonvoltage-gated 1 alphaSource|GeneCards
FLJ30046FLJ30046hypothetical protein FLJ30046Source|GeneCards
UVRAGUVRAGUV radiation resistance associated geneSource|GeneCards

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