[an error occurred while processing this directive]
Gene set: V$E47_02 (C3:TFAC:0038)
Standard nameV$E47_02
Systematic nameC3:TFAC:0038
Brief descriptionGenes with 3'UTR containing motif NNNMRCAGGTGTTMNN which matches annotation for TCF3: Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

Toggle abstract view

XX
 XX
 XX
 FA E47
 XX
 SY BCF-1; E2A.E47; E2A-E47;
E47; IEBP1 (rat); E2A.
 XX
 OS human, Homo sapiens
 OC
eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda;
mammalia;
 OC eutheria; primates
 XX
 XX
 CL C0010;
bHLH; 1.2.1.0.1.2.
 XX
 SZ 651 AA; 67.3 kDa (cDNA)
 XX

XX
 SC reconstituted from hE12 (common N- and C-termini) and
conceptually
 SC translated fragments from EMBL/GenBank/DDBJ
#M65214 and #M24404
 XX
 FT 1 83 trans-activation domain
[4].
 FT 345 408 trans-activation domain [4].
 FT 397 425
leucine repeat (L2TL2).
 FT 547 556 basic region.
 FT 547
600 PF00010; HLH.
 FT 552 605 SM00353; HLH.
 FT 557 600
helix-loop-helix domain.
 FT 560 577 Helix 1.
 FT 578 584
Loop.
 XX
 SF basic region contacts DNA, HLH domain is the
dimerization interface [18];
 SF binds DNA avidly as homodimer
(contrasting to E12), or as heterodimer [8];
 SF from crystal
structure: dimerization domain forms a parallel
 SF four-helix-bundle
[3];
 SF helix 1 is one turn longer than in other bHLH proteins
and does not
 SF terminate with a proline, the additional turn
allowing a salt bridge to
 SF form between H576 (at the end
of helix 1) and E600 of helix 2 of the other
 SF E47 peptide
[3];
 SF trans-activation domain is identical with that of
E12;
 SF that around 345-408 is targeted by the bZIP of c-Jun
when repressing
 SF activation by E2A proteins [1];
 XX

CP ubiquitous
 XX
 FF part of MEF-1 complex;
 FF induces
hyperphosphorylation of MyoD upon association;
 FF induces
transcription of IgH, but also of IgH-stimulating Oct-2 gene,
and
 FF recombination-activating genes RAG-1 and -2 thus stimulating
IgH
 FF rearrangement as well [12];
 FF in acute lymphoblastic
leukemias, a t(1,19)(q23,p13.3) translocation fuses
 FF the
trans-activation domain encoded by the E2A gene with the homeobox
of
 FF PBX1 [17] [19] [11];
 FF the resulting chimeric protein
causes acute myeloid leukemia [5] and
 FF induces enhanced
proliferation as well as apoptosis [6];
 XX
 IN T00003;
AS-C T3; fruit fly, Drosophila melanogaster.
 IN T01629; Atoh2;
mouse, Mus musculus.
 IN T01634; BETA2; hamster.
 IN T00204;
E12; human, Homo sapiens.
 IN T00675; E12; rat, Rattus norvegicus.

IN T01787; E12; clawed frog, Xenopus laevis.
 IN T00207; E47;
human, Homo sapiens.
 IN T01569; Hand1; mouse, Mus musculus.

IN T01447; HEN1; rat, Rattus norvegicus.
 IN T01652; HES-5;
rat, Rattus norvegicus.
 IN T00403; Id1; mouse, Mus musculus.

IN T00404; Id2; mouse, Mus musculus.
 IN T01212; Id2; human,
Homo sapiens.
 IN T01658; Id4; mouse, Mus musculus.
 IN
T00506; MEF1; mouse, Mus musculus.
 IN T00512; MRF4; rat, Rattus
norvegicus.
 IN T00520; Myf-4; human, Homo sapiens.
 IN
T00521; Myf-5; human, Homo sapiens.
 IN T00949; Myf-5; clawed
frog, Xenopus laevis.
 IN T00522; Myf-6; human, Homo sapiens.

IN T00524; MyoD; clawed frog, Xenopus laevis.
 IN T00525; MyoD;
human, Homo sapiens.
 IN T00526; MyoD; mouse, Mus musculus.

IN T00527; MyoD; monkey, Cercopithecus aethiops.
 IN T01128;
MyoD; chick, Gallus gallus.
 IN T00528; myogenin; mouse, Mus
musculus.
 IN T00790; Tal-1; human, Homo sapiens.
 IN T01448;
Tal-1beta; human, Homo sapiens.
 IN T01630; Tal-2; human, Homo
sapiens.
 IN T01631; Tal-2; mouse, Mus musculus.
 XX

XX
 XX
 XX
 RN [1]; RE0005830.
 RX MEDLINE; 95166225.

RA Robinson G. L. W. G., Henderson E., Massari M. E., Murre C.,
Stein R.
 RT c-Jun inhibits insulin control element-mediated
transcription by affecting
 RT the transactivation potential
of the E2A gene products
 RL Mol. Cell. Biol. 15:1398-1404
(1995).
 RN [2]; RE0004023.
 RX MEDLINE; 94119077.
 RA
Hsu H.-L., Huang L., Tsan J. T., Funk W., Wright W. E., Hu J.-S.,
Klingston
 RA R. E., Baer R.
 RT Preferred sequence for
DNA recognition by the TAL1 helix-loop-helix proteins
 RL Mol.
Cell. Biol. 14:1256-1265 (1994).
 RN [3]; RE0004025.
 RX
MEDLINE; 95011595.
 RA Ellenberger T., Fass D., Arnaud M.,
Harrison S. C.
 RT Crystal structure of transcription factor
E47: E-box recognition by a basic
 RT region helix-loop-helix
dimer
 RL Genes Dev. 8:970-980 (1994).
 RN [4]; RE0003543.

RX MEDLINE; 93140777.
 RA Quong M. W., Massari M. E., Zwart
R., Murre C.
 RT A new transcriptional-activation motif restricted
to a class of
 RT helix-loop-helix proteins is functionally
conserved in both yeast and
 RT mammalian cells
 RL Mol.
Cell. Biol. 13:792-800 (1993).
 RN [5]; RE0004018.
 RX MEDLINE;
93109319.
 RA Kamps M. P., Baltimore D.
 RT E2A-Pbx1, the
t(1;19) translocation protein of human pre-B-cell acute
 RT
lymphocytic leukemia causes acute myeloid leukemia in mice

RL Mol. Cell. Biol. 13:351-357 (1993).
 RN [6]; RE0005180.

RX MEDLINE; 93386756.
 RA Dedera D. A., Waller E. K., LeBrun
D. P., Sen-Majumdar A., Stevens M. E.,
 RA Barsh G. S., Cleary
M. L.
 RT Chimeric homeobox gene E2A-PBX1 induces proliferation,
apoptosis, and
 RT malignant lymphomas in transgenic mice

RL Cell 74:833-843 (1993).
 RN [7]; RE0003408.
 RX MEDLINE;
92388090.
 RA Chakraborty T., Martin J. F., Olson E. N.

RT Analysis of the oligomerization of myogenin and E2A products
in vivo using
 RT a two-hybrid assay system
 RL J. Biol.
Chem. 267:17498-17501 (1992).
 RN [8]; RE0000231.
 RX MEDLINE;
91105861.
 RA Sun X.-H., Baltimore D.
 RT An inhibitory
domain of E12 transcription factor prevents DNA binding in

RT E12 homodimers but not in E12 heterodimers
 RL Cell 64:459-470
(1991).
 RN [9]; RE0000238.
 RX MEDLINE; 91309143.
 RA
Lassar A. B., Davis R. L., Wright W. E., Kadesch T., Murre C.,
Voronova A.,
 RA Baltimore D., Weintraub H.
 RT Functional
activity of myogenic HLH proteins requires
 RT hetero-oligomerization
with E12/E47-like proteins in vivo
 RL Cell 66:305-315 (1991).

RN [10]; RE0000670.
 RX MEDLINE; 91115096.
 RA Ruezinsky
D., Beckmann H., Kadesh T.
 RT Modulation of the Igh enhancer's
cell type through a genetic switch
 RL Genes Dev. 5:29-37 (1991).

RN [11]; RE0000671.
 RX MEDLINE; 91160969.
 RA Kamps M.
P., Look A. T., Baltimore D.
 RT The human t(1;19) translocation
in pre-B ALL produces multiple nuclear
 RT E2A-Pbx1 fusion
proteins with differing transforming potentials
 RL Genes Dev.
5:358-368 (1991).
 RN [12]; RE0000672.
 RX MEDLINE; 91331308.

RA Schlissel M., Voronova A., Baltimore D.
 RT Helix-loop-helix
transcription factor E47 activates germ-line
 RT immunoglobulin
heavy-chain gene transcription and rearrangement in a
 RT pre-T-cell
line
 RL Genes Dev. 5:1367-1376 (1991).
 RN [13]; RE0001469.

RX MEDLINE; 91117219.
 RA Murre C., Voronova A., Baltimore
D.
 RT B-cell- and myocyte-specific E2-box-binding factors
contain E12/E47-like
 RT subunits
 RL Mol. Cell. Biol. 11:1156-1160
(1991).
 RN [14]; RE0001629.
 RX MEDLINE; 91246170.

RA Hsu H.-L., Cheng J.-T., Chen Q., Baer R.
 RT Enhancer-binding
activity of the tal-1 oncoprotein in association with the

RT E47/E12 helix-loop-helix proteins
 RL Mol. Cell. Biol. 11:3037-3042
(1991).
 RN [15]; RE0004160.
 RX MEDLINE; 91141527.

RA Cordle S. R., Henderson E., Masuoka H., Weil P. A., Stein R.

RT Pancreatic beta-cell-type-specific transcription of the insulin
gene is
 RT mediated by basic helix-loop-helix DNA-binding
proteins
 RL Mol. Cell. Biol. 11:1734-1738 (1991).
 RN [16];
RE0000055.
 RX MEDLINE; 90199896.
 RA Benezra R., Davis
R. L., Lockshon D., Turner D. L., Weintraub H.
 RT The protein
Id: a negative regulator of helix-loop-helix DNA binding
 RT
proteins
 RL Cell 61:49-59 (1990).
 RN [17]; RE0000161.

RX MEDLINE; 90150281.
 RA Nourse J., Mellentin J. D., Galili
N., Wilkinson J., Stanbridge E., Smith
 RA S. D., Cleary M.
L.
 RT Chromosomal translocation t(1;19) results in synthesis
of a homeobox fusion
 RT mRNA that codes for a potential chimeric
transcription factor
 RL Cell 60:535-545 (1990).
 RN [18];
RE0002524.
 RX MEDLINE; 90280447.
 RA Voronova A., Baltimore
D.
 RT Mutations that disrupt DNA binding and dimer formation
in the E47
 RT helix-loop-helix protein map to distinct domains

RL Proc. Natl. Acad. Sci. USA 87:4722-4726 (1990).
 RN [19];
RE0004014.
 RX MEDLINE; 90150282.
 RA Kamps M. P., Murre
C., Sun X. H., Baltimore D.
 RT A new homeobox gene contributes
the DNA binding domain oft the t(1; 19)
 RT translocation protein
in pre-B ALL
 RL Cell 60:547-555 (1990).
 RN [20]; RE0000053.

RX MEDLINE; 89336785.
 RA Murre C., McCaw P. S., Vaessin H.,
Caudy M., Jan L. Y., Jan Y. N., Cabrera
 RA C. V., Buskin J.
N., Hauschka S. D., Lassar A. B., Weintraub H., Baltimore

RA D.
 RT Interactions between heterologous helix-loop-helix
proteins generate
 RT complexes that bind specifically to a
common DNA sequence
 RL Cell 58:537-544 (1989).
 RN [21];
RE0000092.
 RX MEDLINE; 89168418.
 RA Murre C., McCaw P.
S., Baltimore D.
 RT A new DNA binding and dimerization motif
in immunoglobulin enhancer
 RT binding, daughterless, MyoD,
and myc proteins
 RL Cell 56:777-783 (1989).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

260 genes, 260 accessions (Toggle view)

AccessionGeneTitleLinks
FLJ20202FAM46Cfamily with sequence similarity 46, member CSource|GeneCards
OFCC1OFCC1orofacial cleft 1 candidate 1Source|GeneCards
C17ORF37C17ORF37chromosome 17 open reading frame 37 /// chromosome 17 open reading frame 37Source|GeneCards
HIVEP3HIVEP3human immunodeficiency virus type I enhancer binding protein 3Source|GeneCards
MGAT1MGAT1mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferaseSource|GeneCards
IRX4IRX4iroquois homeobox protein 4Source|GeneCards
MGC14161FRMD5FERM domain containing 5Source|GeneCards
DRD3DRD3dopamine receptor D3Source|GeneCards
ZNF532ZNF532zinc finger protein 532Source|GeneCards
FRMD4FRMD4AFERM domain containing 4ASource|GeneCards
SHOX2SHOX2short stature homeobox 2Source|GeneCards
CHRM1CHRM1cholinergic receptor, muscarinic 1Source|GeneCards
PSMD3PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 3Source|GeneCards
MEIS2MEIS2Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)Source|GeneCards
GNA12GNA12guanine nucleotide binding protein (G protein) alpha 12Source|GeneCards
FLJ25323FLJ25323FLJ25323 proteinSource|GeneCards
MLL5MLL5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)Source|GeneCards
SOX12SOX12SRY (sex determining region Y)-box 12Source|GeneCards
SSB1SSB1SPRY domain-containing SOCS box protein SSB-1Source|GeneCards
COL22A1COL22A1collagen, type XXII, alpha 1Source|GeneCards
SEMA4GSEMA4Gsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4GSource|GeneCards
CDH7CDH7cadherin 7, type 2Source|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
BCL2L1BCL2L1BCL2-like 1Source|GeneCards
NR2F6NR2F6nuclear receptor subfamily 2, group F, member 6Source|GeneCards
PLEKHB1PLEKHB1pleckstrin homology domain containing, family B (evectins) member 1Source|GeneCards
MYOCDMYOCDMyocardinSource|GeneCards
DERP6DERP6S-phase 2 proteinSource|GeneCards
PKD1-LIKEPKD1-LIKEpolycystic kidney disease 1-likeSource|GeneCards
ALX3ALX3aristaless-like homeobox 3Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
TRERF1TRERF1transcriptional regulating factor 1Source|GeneCards
IRF1IRF1interferon regulatory factor 1Source|GeneCards
GATMGATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)Source|GeneCards
DDAH1DDAH1dimethylarginine dimethylaminohydrolase 1Source|GeneCards
SERPINI2SERPINI2serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2Source|GeneCards
SCN5ASCN5Asodium channel, voltage-gated, type V, alpha (long QT syndrome 3)Source|GeneCards
SLC9A7SLC9A7solute carrier family 9 (sodium/hydrogen exchanger), isoform 7Source|GeneCards
TFAP2ATFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)Source|GeneCards
C5ORF16C5ORF16chromosome 5 open reading frame 16Source|GeneCards
MGC26594C1ORF169chromosome 1 open reading frame 169Source|GeneCards
NOL4NOL4nucleolar protein 4Source|GeneCards
JPH3JPH3junctophilin 3Source|GeneCards
PCDH17PCDH17protocadherin 17Source|GeneCards
GABREGABREgamma-aminobutyric acid (GABA) A receptor, epsilonSource|GeneCards
CALB1CALB1calbindin 1, 28kDaSource|GeneCards
PCDHA6PCDHA6protocadherin alpha 6Source|GeneCards
BAZ2ABAZ2Abromodomain adjacent to zinc finger domain, 2ASource|GeneCards
HSD3B7HSD3B7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7Source|GeneCards
PCM1PCM1pericentriolar material 1Source|GeneCards
HAPLN2HAPLN2hyaluronan and proteoglycan link protein 2Source|GeneCards
TCF2TCF2transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factorSource|GeneCards
WFIKKNRPWFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2Source|GeneCards
LAF4LAF4lymphoid nuclear protein related to AF4Source|GeneCards
AMACOAMACOA-domain containing protein similar to matrilin and collagenSource|GeneCards
LOC284296LOC284296hypothetical protein LOC284296Source|GeneCards
CELCELcarboxyl ester lipase (bile salt-stimulated lipase)Source|GeneCards
FLJ44313FLJ44313FLJ44313 proteinSource|GeneCards
LOC92558LOC92558hypothetical protein LOC92558Source|GeneCards
HUMMLC2BHUMMLC2Bmyosin light chain 2Source|GeneCards
ARL4AARL4ADP-ribosylation factor-like 4Source|GeneCards
DKFZP564J0123DKFZP564J0123nuclear protein E3-3Source|GeneCards
GLIGLI1glioma-associated oncogene homolog 1 (zinc finger protein)Source|GeneCards
KIAA0922KIAA0922KIAA0922 proteinSource|GeneCards
TOSOFAIM3Fas apoptotic inhibitory molecule 3 /// Fas apoptotic inhibitory molecule 3Source|GeneCards
CUGBP1CUGBP1CUG triplet repeat, RNA binding protein 1Source|GeneCards
POU3F2POU3F2POU domain, class 3, transcription factor 2Source|GeneCards
PURAPURApurine-rich element binding protein ASource|GeneCards
DOC2BDOC2Bdouble C2-like domains, betaSource|GeneCards
ACCN1ACCN1amiloride-sensitive cation channel 1, neuronal (degenerin)Source|GeneCards
KLK1KLK1kallikrein 1, renal/pancreas/salivarySource|GeneCards
TRAM1TRAM1Translocation associated membrane protein 1Source|GeneCards
RAB33ARAB33ARAB33A, member RAS oncogene familySource|GeneCards
NCDNNCDNneurochondrinSource|GeneCards
BMXBMXBMX non-receptor tyrosine kinaseSource|GeneCards
DSCAMDSCAMDown syndrome cell adhesion moleculeSource|GeneCards
KLHL1KLHL1kelch-like 1 (Drosophila)Source|GeneCards
C1ORF22C1ORF22chromosome 1 open reading frame 22Source|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
FOXI1FOXI1forkhead box I1Source|GeneCards
DUSP9DUSP9dual specificity phosphatase 9Source|GeneCards
SLC7A11SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11Source|GeneCards
EHD4EHD4EH-domain containing 4Source|GeneCards
TPM2TPM2tropomyosin 2 (beta)Source|GeneCards
FUT8FUT8fucosyltransferase 8 (alpha (1,6) fucosyltransferase)Source|GeneCards
NPAS2NPAS2neuronal PAS domain protein 2Source|GeneCards
ATOH7ATOH7atonal homolog 7 (Drosophila)Source|GeneCards
RRM2BRRM2Bribonucleotide reductase M2 B (TP53 inducible)Source|GeneCards
TRIB2TRIB2tribbles homolog 2 (Drosophila)Source|GeneCards
BCL9BCL9B-cell CLL/lymphoma 9Source|GeneCards
NOVNOVnephroblastoma overexpressed geneSource|GeneCards
SYNE2SYNE2spectrin repeat containing, nuclear envelope 2Source|GeneCards
PGM3PGM3phosphoglucomutase 3Source|GeneCards
PNUTL2SEPT4septin 4Source|GeneCards
HMGN2HMGN2high-mobility group nucleosomal binding domain 2Source|GeneCards
CPB1CPB1carboxypeptidase B1 (tissue)Source|GeneCards
PRELPPRELPproline arginine-rich end leucine-rich repeat proteinSource|GeneCards
RHOBTB1RHOBTB1Rho-related BTB domain containing 1Source|GeneCards
LISCH7LISCH7liver-specific bHLH-Zip transcription factorSource|GeneCards
FLJ14084TMEM35transmembrane protein 35Source|GeneCards
GRIA1GRIA1glutamate receptor, ionotropic, AMPA 1Source|GeneCards
KIAA0672KIAA0672KIAA0672 gene productSource|GeneCards
CHRNB1CHRNB1cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)Source|GeneCards
DKFZP547K1113DKFZP547K1113hypothetical protein DKFZp547K1113Source|GeneCards
MGC50844TSPAN33tetraspanin 33Source|GeneCards
MIG12MID1IP1MID1 interacting protein 1 (gastrulation specific G12-like (zebrafish))Source|GeneCards
PFTK1PFTK1PFTAIRE protein kinase 1Source|GeneCards
STK22BSTK22Bserine/threonine kinase 22B (spermiogenesis associated)Source|GeneCards
TA-PP2CTA-PP2CT-cell activation protein phosphatase 2CSource|GeneCards
ACCN4ACCN4amiloride-sensitive cation channel 4, pituitarySource|GeneCards
TNFSF13TNFSF13tumor necrosis factor (ligand) superfamily, member 13Source|GeneCards
PRKCQPRKCQprotein kinase C, thetaSource|GeneCards
HDAC3HDAC3histone deacetylase 3Source|GeneCards
SEN54LTSEN54tRNA splicing endonuclease 54 homolog (SEN54, S. cerevisiae)Source|GeneCards
CHD6CHD6chromodomain helicase DNA binding protein 6Source|GeneCards
PPP2R2BPPP2R2Bprotein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoformSource|GeneCards
PARD6APARD6Apar-6 partitioning defective 6 homolog alpha (C.elegans)Source|GeneCards
POU2AF1POU2AF1POU domain, class 2, associating factor 1Source|GeneCards
PCSK4PCSK4proprotein convertase subtilisin/kexin type 4Source|GeneCards
EDG1EDG1endothelial differentiation, sphingolipid G-protein-coupled receptor, 1Source|GeneCards
PNMA1PNMA1paraneoplastic antigen MA1Source|GeneCards
PLEC1PLEC1plectin 1, intermediate filament binding protein 500kDaSource|GeneCards
FLJ13611FLJ13611hypothetical protein FLJ13611Source|GeneCards
HSPB3HSPB3heat shock 27kDa protein 3Source|GeneCards
FGD4FGD4FGD1 family, member 4Source|GeneCards
PYMWIBGwithin bgcn homolog (Drosophila)Source|GeneCards
FLJ10496DALRD3DALR anticodon binding domain containing 3Source|GeneCards
KCNA4KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4Source|GeneCards
BTBD11BTBD11BTB (POZ) domain containing 11Source|GeneCards
WNT10BWNT10Bwingless-type MMTV integration site family, member 10BSource|GeneCards
ABRABRactive BCR-related geneSource|GeneCards
CPNE1CPNE1RNA binding motif protein 12Source|GeneCards
FGF11FGF11fibroblast growth factor 11Source|GeneCards
SNAP25SNAP25synaptosomal-associated protein, 25kDaSource|GeneCards
NUMBLNUMBLnumb homolog (Drosophila)-likeSource|GeneCards
MESDC1MESDC1mesoderm development candidate 1Source|GeneCards
GALR3GALR3galanin receptor 3Source|GeneCards
C11ORF8C11ORF8chromosome 11 open reading frame 8Source|GeneCards
OR10J1OR10J1olfactory receptor, family 10, subfamily J, member 1Source|GeneCards
ZNF503ZNF503zinc finger protein 503Source|GeneCards
SLITRK3SLITRK3SLIT and NTRK-like family, member 3Source|GeneCards
LYL1LYL1lymphoblastic leukemia derived sequence 1Source|GeneCards
MYCMYCV-myc myelocytomatosis viral oncogene homolog (avian)Source|GeneCards
PADI4PADI4peptidyl arginine deiminase, type IVSource|GeneCards
TSGA14TSGA14testis specific, 14Source|GeneCards
AKT2AKT2v-akt murine thymoma viral oncogene homolog 2Source|GeneCards
FLJ35976C1ORF104chromosome 1 open reading frame 104Source|GeneCards
FIBL-6FIBL-6hemicentinSource|GeneCards
TRIFRNF36ring finger protein 36Source|GeneCards
LRRN1LRRN1leucine rich repeat neuronal 1Source|GeneCards
TTNTTNtitinSource|GeneCards
AIG1AIG1androgen-induced 1Source|GeneCards
C13ORF10C13ORF10chromosome 13 open reading frame 10Source|GeneCards
KIAA1001KIAA1001Arylsulfatase GSource|GeneCards
CARTCARTcocaine- and amphetamine-regulated transcriptSource|GeneCards
MGC3265MGC3265hypothetical protein MGC3265Source|GeneCards
HMP19HMP19HMP19 proteinSource|GeneCards
FLJ40457FLJ40457hypothetical protein FLJ40457Source|GeneCards
FLJ46072FLJ46072FLJ46072 proteinSource|GeneCards
ERBB3ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)Source|GeneCards
DSCAML1DSCAML1Down syndrome cell adhesion molecule like 1Source|GeneCards
MGC21416YIPF6Yip1 domain family, member 6Source|GeneCards
AP4S1AP4S1adaptor-related protein complex 4, sigma 1 subunitSource|GeneCards
RWDD2RWDD2RWD domain containing 2Source|GeneCards
BMFBMFBcl-2 modifying factorSource|GeneCards
BZW2BZW2basic leucine zipper and W2 domains 2Source|GeneCards
CNTN5CNTN5contactin 5Source|GeneCards
NDUFS4NDUFS4NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)Source|GeneCards
MKL1MKL1megakaryoblastic leukemia (translocation) 1Source|GeneCards
STC2STC2stanniocalcin 2Source|GeneCards
STRN3STRN3striatin, calmodulin binding protein 3Source|GeneCards
DGKADGKAdiacylglycerol kinase, alpha 80kDaSource|GeneCards
HES6HES6hairy and enhancer of split 6 (Drosophila)Source|GeneCards
MADAMPD1adenosine monophosphate deaminase 1 (isoform M)Source|GeneCards
MAPK12MAPK12mitogen-activated protein kinase 12Source|GeneCards
NXFNPAS4neuronal PAS domain protein 4Source|GeneCards
PCDHA10PCDHA10protocadherin alpha 10Source|GeneCards
LRRN3LRRN3leucine rich repeat neuronal 3Source|GeneCards
KLHL13KLHL13kelch-like 13 (Drosophila)Source|GeneCards
ANXA8ANXA8annexin A8Source|GeneCards
R3HDMR3HDMR3H domain (binds single-stranded nucleic acids) containingSource|GeneCards
UNC5BUNC5Bunc-5 homolog B (C. elegans)Source|GeneCards
CUEDC1CUEDC1CUE domain containing 1Source|GeneCards
SDPRSDPRserum deprivation response (phosphatidylserine binding protein)Source|GeneCards
JMJD1CJMJD1Cjumonji domain containing 1CSource|GeneCards
IDEIDEinsulin-degrading enzymeSource|GeneCards
TNFSF5CD40LGCD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)Source|GeneCards
FAM31BDENND1BDENN/MADD domain containing 1BSource|GeneCards
WDR6WDR6WD repeat domain 6Source|GeneCards
FOXA1FOXA1forkhead box A1Source|GeneCards
A2BP1A2BP1ataxin 2-binding protein 1Source|GeneCards
CASKIN2CASKIN2CASK interacting protein 2Source|GeneCards
FGF13FGF13fibroblast growth factor 13Source|GeneCards
SASH1SASH1SAM and SH3 domain containing 1Source|GeneCards
RIMS2RIMS2regulating synaptic membrane exocytosis 2Source|GeneCards
DDAH2DDAH2dimethylarginine dimethylaminohydrolase 2Source|GeneCards
AMPHAMPHamphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)Source|GeneCards
C9ORF67PPAPDC3phosphatidic acid phosphatase type 2 domain containing 3Source|GeneCards
MEF2DMEF2DMADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)Source|GeneCards
ART1ART1ADP-ribosyltransferase 1Source|GeneCards
24432ACDadrenocortical dysplasia homolog (mouse)Source|GeneCards
RASL10BRASL10BRAS-like, family 10, member BSource|GeneCards
NGFRNGFRnerve growth factor receptor (TNFR superfamily, member 16)Source|GeneCards
GIT1GIT1G protein-coupled receptor kinase-interactor 1Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
ASXL2ASXL2additional sex combs like 2 (Drosophila)Source|GeneCards
RAPGEFL1RAPGEFL1Rap guanine nucleotide exchange factor (GEF)-like 1Source|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
HT017HT017HT017 proteinSource|GeneCards
MLLT6MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6Source|GeneCards
USP46USP46ubiquitin specific protease 46Source|GeneCards
PCDHA1PCDHA1protocadherin alpha 1Source|GeneCards
KIAA0182KIAA0182KIAA0182 proteinSource|GeneCards
ELAVL2ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)Source|GeneCards
KCNN2KCNN2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2Source|GeneCards
PDE4BPDE4Bphosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)Source|GeneCards
USP54USP54ubiquitin specific protease 54Source|GeneCards
EGLN1EGLN1egl nine homolog 1 (C. elegans)Source|GeneCards
SNCAIPSNCAIPsynuclein, alpha interacting protein (synphilin)Source|GeneCards
SYTL2SYTL2synaptotagmin-like 2Source|GeneCards
TAL1TAL1T-cell acute lymphocytic leukemia 1Source|GeneCards
FLJ30296PTCHD1Patched domain containing 1Source|GeneCards
TEAD2TEAD2TEA domain family member 2Source|GeneCards
ASB5ASB5ankyrin repeat and SOCS box-containing 5Source|GeneCards
EGFL4EGFL4EGF-like-domain, multiple 4Source|GeneCards
DMPKDMPKdystrophia myotonica-protein kinaseSource|GeneCards
GFAPGFAPglial fibrillary acidic proteinSource|GeneCards
FLJ20619TTC22tetratricopeptide repeat domain 22Source|GeneCards
ADAM12ADAM12a disintegrin and metalloproteinase domain 12 (meltrin alpha)Source|GeneCards
CRSP7CRSP7cofactor required for Sp1 transcriptional activation, subunit 7, 70kDaSource|GeneCards
RIPXRIPXrap2 interacting protein xSource|GeneCards
LUC7LLUC7LLUC7-like (S. cerevisiae)Source|GeneCards
TRIM23TRIM23tripartite motif-containing 23Source|GeneCards
MMP16MMP16matrix metalloproteinase 16 (membrane-inserted)Source|GeneCards
ARMCX2ARMCX2armadillo repeat containing, X-linked 2Source|GeneCards
THRATHRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Source|GeneCards
LMO2LMO2LIM domain only 2 (rhombotin-like 1)Source|GeneCards
MYO18AMYO18Amyosin XVIIIASource|GeneCards
CNTN6CNTN6contactin 6Source|GeneCards
NPTX2NPTX2neuronal pentraxin IISource|GeneCards
FLJ33817FLJ33817hypothetical protein FLJ33817Source|GeneCards
TBDN100NARG1NMDA receptor regulated 1Source|GeneCards
ARID5AARID5AAT rich interactive domain 5A (MRF1-like)Source|GeneCards
BNC2BNC2basonuclin 2Source|GeneCards
MEF2CMEF2CMADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)Source|GeneCards
C6ORF62C6ORF62chromosome 6 open reading frame 62Source|GeneCards
STK3STK3serine/threonine kinase 3 (STE20 homolog, yeast)Source|GeneCards
DULLARDDULLARDdullard homolog (Xenopus laevis)Source|GeneCards
BRUNOL4BRUNOL4bruno-like 4, RNA binding protein (Drosophila)Source|GeneCards
TPI1TPI1triosephosphate isomerase 1Source|GeneCards
HOXA7HOXA7homeo box A7Source|GeneCards
FLJ10970FLJ10970hypothetical protein FLJ10970Source|GeneCards
PODXLPODXLpodocalyxin-likeSource|GeneCards
GJA4GJA4gap junction protein, alpha 4, 37kDa (connexin 37)Source|GeneCards
MGC42157MGC42157hypothetical protein MGC42157Source|GeneCards
FLJ14107FLJ14107hypothetical protein FLJ14107Source|GeneCards
BTBD3BTBD3BTB (POZ) domain containing 3Source|GeneCards
FLJ21918RBM35BRNA binding motif protein 35BSource|GeneCards
EPHB6EPHB6EphB6Source|GeneCards
AFTIPHILINAFTIPHILINaftiphilin proteinSource|GeneCards

[an error occurred while processing this directive]