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Gene set: V$EGR2_01 (C3:TFAC:0158)
Standard nameV$EGR2_01
Systematic nameC3:TFAC:0158
Brief descriptionGenes with 3'UTR containing motif NTGCGTRGGCGK which matches annotation for EGR2: early growth response 2 (Krox-20 homolog, Drosophila)
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA Krox-20
 XX
 SY EGR2 (human); Krox-20.

XX
 OS mouse, Mus musculus
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; rodentia;
myomorpha; muridae; murinae
 XX
 XX
 CL C0001; CH; 2.3.2.1.3.

XX
 SZ 420 AA
 XX
 XX
 SC SwissProt #P08152
 XX

FT 287 311 PF00096; zf-C2H2.
 FT 287 311 SM00355; ZnF_C2H2.

FT 289 314 zinc finger 1.
 FT 317 339 SM00355; ZnF_C2H2.

FT 317 339 PF00096; zf-C2H2.
 FT 319 339 zinc finger 2.

FT 345 367 PF00096; zf-C2H2.
 FT 345 367 SM00355; ZnF_C2H2.

FT 347 367 zinc finger 3.
 XX
 SF 3 zinc finger motifs;

SF phosphorylation;
 SF glycosylation;
 SF each finger spans
3 nucleotides;
 SF discrimination between Krox-20 and Sp1 binding
sites by 2 side chains;
 XX
 CP hindbrain (rhombomeres 3
and 5), neural crest, neural crest-derived
 CP boundary caps,
glial components of cranial and spinal ganglia; in immune

CP system, is expressed equally in both T-helpers 1 and T-helpers
2 cells [1]
 XX
 IN T02370; Nab1; mouse, Mus musculus.

XX
 XX
 XX
 XX
 RN [1]; RE0022852.
 RX MEDLINE;
10755616.
 RA Rengarajan J., Mittelstadt P. R., Mages H. W.,
Gerth A. J., Kroczek R. A.,
 RA Ashwell J. D., Glimcher L.
H.
 RT Sequential involvement of NFAT and Egr transcription
factors in FasL
 RT regulation.
 RL Immunity 12:293-300
(2000).
 RN [2]; RE0000031.
 RX MEDLINE; 91234777.
 RA
Gilardi P., Schneider-Maunoury S., Charnay P.
 RT Krox-20:
a candidate gene for the regulation of pattern formation in the

RT hindbrain
 RL Biochimie 73:85-91 (1991).
 RN [3]; RE0001890.

RX MEDLINE; 91095025.
 RA Nardelli J., Gibson T. J., Vesque
C., Charnay P.
 RT Base sequence discrimination by zinc-finger
DNA-binding domains
 RL Nature 349:175-178 (1991).
 RN [4];
RE0002757.
 RX MEDLINE; 90287135.
 RA Lemaire P., Vesque
C., Schmitt J., Stunnenberg H., Frank R., Charnay P.
 RT The
serum-inducible mouse gene Krox-24 encodes a sequence-specific

RT transcriptional activator
 RL Mol. Cell. Biol. 10:3456-3467
(1990).
 RN [5]; RE0001889.
 RX MEDLINE; 89127493.
 RA
Wilkinson D. G., Bhatt S., Chavrier P., Bravo R., Charnay P.

RT Segment-specific expression of a zinc-finger gene in the developing
nervous
 RT system of the mouse
 RL Nature 337:461-464 (1989).

XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

203 genes, 203 accessions (Toggle view)

AccessionGeneTitleLinks
EGR3EGR3early growth response 3Source|GeneCards
ASE-1CD3EAPCD3E antigen, epsilon polypeptide associated proteinSource|GeneCards
SOX4SOX4SRY (sex determining region Y)-box 4Source|GeneCards
EGR1EGR1early growth response 1Source|GeneCards
RALGPS2RALGPS2Ral GEF with PH domain and SH3 binding motif 2Source|GeneCards
TAF11TAF11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDaSource|GeneCards
GPC4GPC4glypican 4Source|GeneCards
FUSFUSfusion (involved in t(12;16) in malignant liposarcoma)Source|GeneCards
SPG3ASPG3Aspastic paraplegia 3A (autosomal dominant)Source|GeneCards
MNTMNTMAX binding proteinSource|GeneCards
LOC138046LOC138046hypothetical protein LOC138046Source|GeneCards
SUMO2SUMO2SMT3 suppressor of mif two 3 homolog 2 (yeast)Source|GeneCards
ERFERFEts2 repressor factorSource|GeneCards
LOC144747LOC144747hypothetical protein LOC144747Source|GeneCards
ZHX2ZHX2transcription factor ZHX2Source|GeneCards
LOC285513LOC285513hypothetical protein LOC285513Source|GeneCards
ITPKAITPKAinositol 1,4,5-trisphosphate 3-kinase ASource|GeneCards
WWP2WWP2Nedd-4-like ubiquitin-protein ligaseSource|GeneCards
HNRPDLHNRPDLheterogeneous nuclear ribonucleoprotein D-likeSource|GeneCards
HRKHRKharakiri, BCL2 interacting protein (contains only BH3 domain)Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
PTPN7PTPN7protein tyrosine phosphatase, non-receptor type 7Source|GeneCards
CRSP2CRSP2cofactor required for Sp1 transcriptional activation, subunit 2, 150kDaSource|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
MAP3K3MAP3K3mitogen-activated protein kinase kinase kinase 3Source|GeneCards
NRCAMNRCAMneuronal cell adhesion moleculeSource|GeneCards
MRC2MRC2mannose receptor, C type 2Source|GeneCards
DNCL1DNCL1dynein, cytoplasmic, light polypeptide 1Source|GeneCards
SCN5ASCN5Asodium channel, voltage-gated, type V, alpha (long QT syndrome 3)Source|GeneCards
FLJ11011UBE2Wubiquitin-conjugating enzyme E2W (putative)Source|GeneCards
USP4USP4ubiquitin specific protease 4 (proto-oncogene)Source|GeneCards
USP37USP37ubiquitin specific protease 37Source|GeneCards
SRFSRFserum response factor (c-fos serum response element-binding transcription factor)Source|GeneCards
VGFVGFVGF nerve growth factor inducibleSource|GeneCards
GABRA1GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 1Source|GeneCards
SDBCAG84SDBCAG84serologically defined breast cancer antigen 84Source|GeneCards
SH3GL3SH3GL3SH3-domain GRB2-like 3Source|GeneCards
DKFZP686L20145WDR44WD repeat domain 44Source|GeneCards
RRBP1RRBP1ribosome binding protein 1 homolog 180kDa (dog)Source|GeneCards
ATP6V1C1ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1Source|GeneCards
DESDESdesminSource|GeneCards
NRGNNRGNneurogranin (protein kinase C substrate, RC3)Source|GeneCards
MGC23937MGC23937hypothetical protein MGC23937 similar to CG4798Source|GeneCards
MGC35138C11ORF35chromosome 11 open reading frame 35Source|GeneCards
REREREREarginine-glutamic acid dipeptide (RE) repeatsSource|GeneCards
GPR132GPR132G protein-coupled receptor 132Source|GeneCards
KIAA1449WDR48WD repeat domain 48Source|GeneCards
YME1L1YME1L1YME1-like 1 (S. cerevisiae)Source|GeneCards
NFATC3NFATC3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3Source|GeneCards
HAN11WDR68WD repeat domain 68Source|GeneCards
PRKCEPRKCEprotein kinase C, epsilonSource|GeneCards
DSCAMDSCAMDown syndrome cell adhesion moleculeSource|GeneCards
GABRQGABRQgamma-aminobutyric acid (GABA) receptor, thetaSource|GeneCards
PPP1R1BPPP1R1Bprotein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32)Source|GeneCards
FSHBFSHBfollicle stimulating hormone, beta polypeptideSource|GeneCards
MYBMYBv-myb myeloblastosis viral oncogene homolog (avian)Source|GeneCards
CMASCMAScytidine monophosphate N-acetylneuraminic acid synthetaseSource|GeneCards
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)Source|GeneCards
BCL2A1BCL2A1BCL2-related protein A1Source|GeneCards
EMID2EMID2EMI domain containing 2Source|GeneCards
RIMS1RIMS1regulating synaptic membrane exocytosis 1Source|GeneCards
SMARCA5SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5Source|GeneCards
KIAA1036VASH1vasohibin 1Source|GeneCards
FBXL19FBXL19F-box and leucine-rich repeat protein 19Source|GeneCards
DOC2ADOC2Adouble C2-like domains, alphaSource|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
EPHB1EPHB1EphB1Source|GeneCards
LOC133619LOC133619hypothetical protein MGC12103Source|GeneCards
DNASE1L2DNASE1L2deoxyribonuclease I-like 2Source|GeneCards
KCNJ1KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1Source|GeneCards
C11ORF13RASSF7Ras association (RalGDS/AF-6) domain family 7Source|GeneCards
EPHB3EPHB3EphB3Source|GeneCards
ZNF281ZNF281zinc finger protein 281Source|GeneCards
UNC84BUNC84Bunc-84 homolog B (C. elegans)Source|GeneCards
HMGN2HMGN2high-mobility group nucleosomal binding domain 2Source|GeneCards
CGGBP1CGGBP1CGG triplet repeat binding protein 1Source|GeneCards
RBBP6RBBP6retinoblastoma binding protein 6Source|GeneCards
KLF5KLF5Kruppel-like factor 5 (intestinal)Source|GeneCards
RHBDL4RHBDL4rhomboid, veinlet-like 4 (Drosophila)Source|GeneCards
PDZK7PDZK7PDZ domain containing 7Source|GeneCards
ETV4ETV4ets variant gene 4 (E1A enhancer binding protein, E1AF)Source|GeneCards
DVL2DVL2dishevelled, dsh homolog 2 (Drosophila)Source|GeneCards
XKXKKell blood group precursor (McLeod phenotype)Source|GeneCards
HRD1SYVN1synovial apoptosis inhibitor 1, synoviolinSource|GeneCards
PCOLCEPCOLCEprocollagen C-endopeptidase enhancerSource|GeneCards
SORCS3SORCS3VPS10 domain receptor protein SORCS 3Source|GeneCards
CFL1CFL1cofilin 1 (non-muscle)Source|GeneCards
KLF4KLF4Kruppel-like factor 4 (gut)Source|GeneCards
KREMEN2KREMEN2kringle containing transmembrane protein 2Source|GeneCards
KPI2LMTK2lemur tyrosine kinase 2Source|GeneCards
PDCD6IPPDCD6IPprogrammed cell death 6 interacting proteinSource|GeneCards
CSTF3CSTF3cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDaSource|GeneCards
SERTAD1SERTAD1SERTA domain containing 1Source|GeneCards
SH3BP1SH3BP1SH3-domain binding protein 1Source|GeneCards
CA11CA11carbonic anhydrase XISource|GeneCards
THPOTHPOthrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor)Source|GeneCards
HOXB6HOXB6homeo box B6Source|GeneCards
SEC14L1SEC14L1SEC14-like 1 (S. cerevisiae)Source|GeneCards
IMP-1IMP-1IGF-II mRNA-binding protein 1Source|GeneCards
TP53I11TP53I11tumor protein p53 inducible protein 11Source|GeneCards
CLTCCLTCclathrin, heavy polypeptide (Hc)Source|GeneCards
CHRDCHRDchordinSource|GeneCards
MAN2A2MAN2A2mannosidase, alpha, class 2A, member 2Source|GeneCards
XPR1XPR1xenotropic and polytropic retrovirus receptorSource|GeneCards
RELARELAv-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)Source|GeneCards
PRR3PRR3Proline rich 3Source|GeneCards
SNAP25SNAP25synaptosomal-associated protein, 25kDaSource|GeneCards
ARPP-21ARPP-21cyclic AMP-regulated phosphoprotein, 21 kDSource|GeneCards
SIRT1SIRT1sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)Source|GeneCards
ITGB8ITGB8integrin, beta 8Source|GeneCards
GLTSCR2GLTSCR2glioma tumor suppressor candidate region gene 2Source|GeneCards
KIF1CKIF1Ckinesin family member 1CSource|GeneCards
EIF3S9EIF3S9eukaryotic translation initiation factor 3, subunit 9 eta, 116kDaSource|GeneCards
NAB2NAB2NGFI-A binding protein 2 (EGR1 binding protein 2)Source|GeneCards
DC-UBPDC-UBPdendritic cell-derived ubiquitin-like proteinSource|GeneCards
FBXL20FBXL20F-box and leucine-rich repeat protein 20Source|GeneCards
LGI1LGI1leucine-rich, glioma inactivated 1Source|GeneCards
ZCCHC5ZCCHC5zinc finger, CCHC domain containing 5Source|GeneCards
LOC56901LOC56901NADH:ubiquinone oxidoreductase MLRQ subunit homologSource|GeneCards
SMYD5SMYD5SMYD family member 5Source|GeneCards
ANKS1ANKS1ankyrin repeat and sterile alpha motif domain containing 1Source|GeneCards
KCNQ5KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5Source|GeneCards
PRKAG1PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunitSource|GeneCards
TBC1D10TBC1D10ATBC1 domain family, member 10ASource|GeneCards
GPRGPRputative G protein coupled receptorSource|GeneCards
BCL6BCL6B-cell CLL/lymphoma 6 (zinc finger protein 51)Source|GeneCards
ADAMTS15ADAMTS15a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15Source|GeneCards
CX3CL1CX3CL1chemokine (C-X3-C motif) ligand 1Source|GeneCards
PRG-3PRG-3plasticity related gene 3Source|GeneCards
BDG29ZCCHC14zinc finger, CCHC domain containing 14Source|GeneCards
BAI3BAI3brain-specific angiogenesis inhibitor 3Source|GeneCards
DIAPH1DIAPH1diaphanous homolog 1 (Drosophila)Source|GeneCards
MASAMASAE-1 enzymeSource|GeneCards
GSH1GSH1GS homeobox 1Source|GeneCards
ZNF575ZNF575zinc finger protein 575Source|GeneCards
VTNVTNvitronectin (serum spreading factor, somatomedin B, complement S-protein)Source|GeneCards
MAP1AMAP1Amicrotubule-associated protein 1ASource|GeneCards
RQCD1RQCD1RCD1 required for cell differentiation1 homolog (S. pombe)Source|GeneCards
MASTLMASTLmicrotubule associated serine/threonine kinase-likeSource|GeneCards
COLEC12COLEC12collectin sub-family member 12Source|GeneCards
KCNIP2KCNIP2Kv channel interacting protein 2Source|GeneCards
A2LPATXN2Lataxin 2-likeSource|GeneCards
ATP2A2ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2Source|GeneCards
TNFSF5CD40LGCD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)Source|GeneCards
AK2AK2adenylate kinase 2Source|GeneCards
TNFSF6FASLGFas ligand (TNF superfamily, member 6)Source|GeneCards
PABPC4PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)Source|GeneCards
SNIPSNIPSNAP25-interacting proteinSource|GeneCards
WNT1WNT1wingless-type MMTV integration site family, member 1Source|GeneCards
CGI-69CGI-69CGI-69 proteinSource|GeneCards
LOC153222LOC153222adult retina proteinSource|GeneCards
MGC45419PNCKpregnancy upregulated non-ubiquitously expressed CaM kinaseSource|GeneCards
PDGFRBPDGFRBplatelet-derived growth factor receptor, beta polypeptideSource|GeneCards
C9ORF126C9ORF126chromosome 9 open reading frame 126Source|GeneCards
RAPGEFL1RAPGEFL1Rap guanine nucleotide exchange factor (GEF)-like 1Source|GeneCards
HMG20BHMG20Bhigh-mobility group 20BSource|GeneCards
HDAC9HDAC9histone deacetylase 9Source|GeneCards
KIAA0182KIAA0182KIAA0182 proteinSource|GeneCards
ODDGJA1gap junction protein, alpha 1, 43kDa (connexin 43)Source|GeneCards
SPTBSPTBspectrin, beta, erythrocytic (includes spherocytosis, clinical type I)Source|GeneCards
SMAD1SMAD1SMAD, mothers against DPP homolog 1 (Drosophila)Source|GeneCards
PTGESPTGESprostaglandin E synthaseSource|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
C10ORF4C10ORF4chromosome 10 open reading frame 4Source|GeneCards
NKX2-2NKX2-2NK2 transcription factor related, locus 2 (Drosophila)Source|GeneCards
VEGFVEGFvascular endothelial growth factorSource|GeneCards
EGFL9EGFL9EGF-like-domain, multiple 9Source|GeneCards
FLJ30296PTCHD1Patched domain containing 1Source|GeneCards
SSTR1SSTR1somatostatin receptor 1Source|GeneCards
GUCY1A2GUCY1A2guanylate cyclase 1, soluble, alpha 2Source|GeneCards
C9ORF72C9ORF72chromosome 9 open reading frame 72Source|GeneCards
H2AFY2H2AFY2H2A histone family, member Y2Source|GeneCards
MGC5395MGC5395hypothetical protein MGC5395Source|GeneCards
BA108L7.2BA108L7.2similar to rat tricarboxylate carrier-like proteinSource|GeneCards
GNL1GNL1guanine nucleotide binding protein-like 1Source|GeneCards
KIAA1539KIAA1539KIAA1539Source|GeneCards
SSTR3SSTR3somatostatin receptor 3Source|GeneCards
GNAI2GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2Source|GeneCards
BAHD1BAHD1bromo adjacent homology domain containing 1Source|GeneCards
RUNX1RUNX1runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)Source|GeneCards
THRATHRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)Source|GeneCards
AKAP10AKAP10A kinase (PRKA) anchor protein 10Source|GeneCards
KIAA1959KIAA1959nm23-phosphorylated unknown substrateSource|GeneCards
PDGFBPDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)Source|GeneCards
SIN3ASIN3ASIN3 homolog A, transcriptional regulator (yeast)Source|GeneCards
ITPR1ITPR1inositol 1,4,5-triphosphate receptor, type 1Source|GeneCards
CDKN2CCDKN2Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Source|GeneCards
LOC159090LOC159090similar to hypothetical protein MGC17347Source|GeneCards
CAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase (CaM kinase) II alphaSource|GeneCards
KCNB2KCNB2potassium voltage-gated channel, Shab-related subfamily, member 2Source|GeneCards
KCNH3KCNH3potassium voltage-gated channel, subfamily H (eag-related), member 3Source|GeneCards
BRUNOL4BRUNOL4bruno-like 4, RNA binding protein (Drosophila)Source|GeneCards
AP1S1AP1S1adaptor-related protein complex 1, sigma 1 subunitSource|GeneCards
ANKHANKHankylosis, progressive homolog (mouse)Source|GeneCards
INCA1INCA1Inhibitor of CDK interacting with cyclin A1Source|GeneCards
NUP107NUP107nuclear pore complex proteinSource|GeneCards
SARM1SARM1sterile alpha and TIR motif containing 1Source|GeneCards
PLXNC1PLXNC1plexin C1Source|GeneCards
AXUD1AXUD1AXIN1 up-regulated 1Source|GeneCards
FLJ10546RNF184ring finger protein 184Source|GeneCards
FLJ21918RBM35BRNA binding motif protein 35BSource|GeneCards
PKD1PKD1polycystic kidney disease 1 (autosomal dominant)Source|GeneCards
AFTIPHILINAFTIPHILINaftiphilin proteinSource|GeneCards

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