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Gene set: V$GATA2_01 (C3:TFAC:0041)
Standard nameV$GATA2_01
Systematic nameC3:TFAC:0041
Brief descriptionGenes with 3'UTR containing motif NNNGATRNNN which matches annotation for GATA2: GATA binding protein 2
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA GATA-2
 XX
 SY GATA-2; NF-E1b (chick).

XX
 OS human, Homo sapiens
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0003; CC (g); 2.2.1.1.2.
 XX
 SZ 480 AA;
50.3 kDa (cDNA)
 XX
 XX
 SC SwissProt #P23769
 XX

FT 289 339 SM00401; ZnF_GATA.
 FT 291 330 PF00320; GATA.

FT 295 319 zinc finger 1.
 FT 343 393 SM00401; ZnF_GATA.

FT 345 384 PF00320; GATA.
 FT 349 373 zinc finger 2.
 XX

SF 2 zinc finger motifs
 XX
 CN T-lymphocyte cell lines
(MOLT4, Jurkat) [2]
 EX blood,neutrophil granulocyte,,adult;very
high; northern blot; total RNA;
 EX [1].
 EX prepuce of
penis,fibroblast,,adult;detectable; northern blot; total RNA;

EX [3].
 XX
 FF down-regulated in HL-60 <0111> and EA.hy926
<0970> cells upon retinoic acid
 FF treatment [2]
 XX

IN T04110; HDAC3; human, Homo sapiens.
 IN T05252; HDAC5; human,
Homo sapiens.
 IN T02251; Lmo2; mouse, Mus musculus.
 XX

XX
 XX
 XX
 RN [1]; RE0013448.
 RX MEDLINE; 93283670.

RA Zon L. I., Yamaguchi Y., Yee K., Albee E. A., Kimura A., Bennett
J. C.,
 RA Orkin S. H., Ackerman S. J.
 RT Expression of
mRNA for the GATA-binding proteins in human eosinophils and

RT basophils: potential role in gene transcription.
 RL Blood
81:3234-3241 (1993).
 RN [2]; RE0013452.
 RX MEDLINE; 92112773.

RA Dorfman D. M., Wilson D. B., Bruns G. A. P., Orkin S. H.

RT Human transcription factor GATA-2. Evidence for regulation
of
 RT preproendothelin-1 gene expression in endothelial cells.

RL J. Biol. Chem. 267:1279-1285 (1992).
 RN [3]; RE0000948.

RX MEDLINE; 91340773.
 RA Lee M.-H., Temizer D. H., Clifford
J. A., Quertermous T.
 RT Cloning of the GATA-binding protein
that regulates endothelin-1 gene
 RT expression in endothelial
cells
 RL J. Biol. Chem. 266:16188-16192 (1991).
 RN [4];
RE0013449.
 RX MEDLINE; 96224280.
 RA Melotti P., Calabretta
B.
 RT The transcription factors c-myb and GATA-2 act independently
in the
 RT regulation of normal hematopoiesis.
 RL Proc.
Natl. Acad. Sci. USA 93:5313-5318 (1996).
 RN [5]; RE0002959.

RX MEDLINE; 93309433.
 RA Merika M., Orkin S. H.
 RT DNA-binding
specificity of GATA family transcription factors
 RL Mol. Cell.
Biol. 13:3999-4010 (1993).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

107 genes, 107 accessions (Toggle view)

AccessionGeneTitleLinks
ETPCYT2phosphate cytidylyltransferase 2, ethanolamineSource|GeneCards
HS6ST3HS6ST3heparan sulfate 6-O-sulfotransferase 3Source|GeneCards
NEURLNEURLneuralized-like (Drosophila)Source|GeneCards
GREM1GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)Source|GeneCards
WNT5AWNT5Awingless-type MMTV integration site family, member 5ASource|GeneCards
RAB34RAB34RAB34, member RAS oncogene familySource|GeneCards
ABCB6ABCB6ATP-binding cassette, sub-family B (MDR/TAP), member 6Source|GeneCards
ST7LST7Lsuppression of tumorigenicity 7 likeSource|GeneCards
MPV17MPV17MpV17 transgene, murine homolog, glomerulosclerosisSource|GeneCards
FKBP2FKBP2FK506 binding protein 2, 13kDaSource|GeneCards
NXPH3NXPH3neurexophilin 3Source|GeneCards
UBTFUBTFupstream binding transcription factor, RNA polymerase ISource|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
MAML3MAML3Mastermind-like 3 (Drosophila)Source|GeneCards
ANGPT1ANGPT1angiopoietin 1Source|GeneCards
MGC42090MGC42090hypothetical protein MGC42090Source|GeneCards
SYN1SYN1synapsin ISource|GeneCards
SP7SP7Sp7 transcription factorSource|GeneCards
TFAP2BL1TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta)Source|GeneCards
CDC27CDC27cell division cycle 27Source|GeneCards
UBE2HUBE2Hubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)Source|GeneCards
POLD4POLD4polymerase (DNA-directed), delta 4Source|GeneCards
LRP1LRP1low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)Source|GeneCards
PKD1-LIKEPKD1-LIKEpolycystic kidney disease 1-likeSource|GeneCards
GATA3GATA3GATA binding protein 3Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
CAPZA1CAPZA1capping protein (actin filament) muscle Z-line, alpha 1Source|GeneCards
PHF6PHF6PHD finger protein 6Source|GeneCards
BLCAPBLCAPbladder cancer associated proteinSource|GeneCards
TCF7L1TCF7L1transcription factor 7-like 1 (T-cell specific, HMG-box)Source|GeneCards
RBJRBJRas-associated protein Rap1Source|GeneCards
DPF3DPF3D4, zinc and double PHD fingers, family 3Source|GeneCards
YWHAEYWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptideSource|GeneCards
CGI-30DPH5DPH5 homolog (S. cerevisiae)Source|GeneCards
ACTN1ACTN1actinin, alpha 1Source|GeneCards
DPYSL2DPYSL2dihydropyrimidinase-like 2Source|GeneCards
FLJ10539SHQ1SHQ1 homolog (S. cerevisiae)Source|GeneCards
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDaSource|GeneCards
SP3SP3Sp3 transcription factorSource|GeneCards
C5ORF16C5ORF16chromosome 5 open reading frame 16Source|GeneCards
SALL1SALL1sal-like 1 (Drosophila)Source|GeneCards
GRID2GRID2glutamate receptor, ionotropic, delta 2Source|GeneCards
FBXW11FBXW11F-box and WD-40 domain protein 11Source|GeneCards
SLC8A3SLC8A3solute carrier family 8 (sodium-calcium exchanger), member 3Source|GeneCards
LOC255743LOC255743hypothetical protein LOC255743Source|GeneCards
MCTS1MCTS1malignant T cell amplified sequence 1Source|GeneCards
AMOTAMOTangiomotinSource|GeneCards
SRRM1SRRM1serine/arginine repetitive matrix 1Source|GeneCards
EIF4G1EIF4G1eukaryotic translation initiation factor 4 gamma, 1Source|GeneCards
APEG1APEG1aortic preferentially expressed protein 1Source|GeneCards
FOXA2FOXA2forkhead box A2Source|GeneCards
CNNM1CNNM1cyclin M1Source|GeneCards
HNRPLHNRPLheterogeneous nuclear ribonucleoprotein LSource|GeneCards
SFRS2SFRS2splicing factor, arginine/serine-rich 2Source|GeneCards
SYMPKSYMPKsymplekinSource|GeneCards
PDLIM4PDLIM4PDZ and LIM domain 4Source|GeneCards
FBXW7FBXW7F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)Source|GeneCards
GL004C2ORF33Chromosome 2 open reading frame 33Source|GeneCards
REPS2REPS2RALBP1 associated Eps domain containing 2Source|GeneCards
KLHL5KLHL5kelch-like 5 (Drosophila)Source|GeneCards
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptideSource|GeneCards
POU3F1POU3F1POU domain, class 3, transcription factor 1Source|GeneCards
RAB3CRAB3CRAB3C, member RAS oncogene familySource|GeneCards
RPL8RPL8ribosomal protein L8Source|GeneCards
DNAJB5DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5Source|GeneCards
NCDNNCDNneurochondrinSource|GeneCards
TRA2ATRA2Atransformer-2 alphaSource|GeneCards
PHOX2BPHOX2Bpaired-like homeobox 2bSource|GeneCards
C10ORF6C10ORF6chromosome 10 open reading frame 6Source|GeneCards
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2ASource|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
DKFZP761C169GPBP1GC-rich promoter binding protein 1Source|GeneCards
FOXA3FOXA3forkhead box A3Source|GeneCards
KPNB1KPNB1karyopherin (importin) beta 1Source|GeneCards
ZNF335ZNF335zinc finger protein 335Source|GeneCards
ZNF161ZNF161zinc finger protein 161Source|GeneCards
RBMS2RBMS2RNA binding motif, single stranded interacting protein 2Source|GeneCards
HRIHFB2122TRIOBPTRIO and F-actin binding proteinSource|GeneCards
SPOPSPOPspeckle-type POZ proteinSource|GeneCards
K-ALPHA-1K-ALPHA-1tubulin, alpha, ubiquitousSource|GeneCards
PTK7PTK7PTK7 protein tyrosine kinase 7Source|GeneCards
MGC21688MGC21688hypothetical protein MGC21688Source|GeneCards
CRMP1CRMP1collapsin response mediator protein 1Source|GeneCards
C18ORF23C18ORF23chromosome 18 open reading frame 23Source|GeneCards
HOXA10HOXA10homeo box A10Source|GeneCards
MGC46534ATXN7L2ataxin 7-like 2Source|GeneCards
OAZ2OAZ2ornithine decarboxylase antizyme 2Source|GeneCards
PRKD2PRKD2protein kinase D2Source|GeneCards
CCM1CCM1cerebral cavernous malformations 1Source|GeneCards
TTBK2TTBK2tau tubulin kinase 2Source|GeneCards
HDAC3HDAC3histone deacetylase 3Source|GeneCards
ABHD8ABHD8abhydrolase domain containing 8Source|GeneCards
LHX6LHX6LIM homeobox 6Source|GeneCards
SLC39A5SLC39A5solute carrier family 39 (metal ion transporter), member 5Source|GeneCards
KCNB2KCNB2potassium voltage-gated channel, Shab-related subfamily, member 2Source|GeneCards
PPP2R2APPP2R2Aprotein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoformSource|GeneCards
GRIK2GRIK2Glutamate receptor, ionotropic, kainate 2Source|GeneCards
NFIANFIAnuclear factor I/ASource|GeneCards
COBRA1COBRA1cofactor of BRCA1Source|GeneCards
VASPVASPvasodilator-stimulated phosphoproteinSource|GeneCards
PLXNC1PLXNC1plexin C1Source|GeneCards
ZNRF2ZNRF2Zinc and ring finger 2Source|GeneCards
GNASGNASGNAS complex locusSource|GeneCards
CNOT3CNOT3CCR4-NOT transcription complex, subunit 3Source|GeneCards
RBMS3RBMS3RNA binding motif, single stranded interacting proteinSource|GeneCards
HOXB6HOXB6homeo box B6Source|GeneCards
PPOXPPOXprotoporphyrinogen oxidaseSource|GeneCards

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