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Gene set: V$MAX_01 (C3:TFAC:0071)
Standard nameV$MAX_01
Systematic nameC3:TFAC:0071
Brief descriptionGenes with 3'UTR containing motif NNANCACGTGNTNN which matches annotation for MAX: MAX protein
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA Max1
 XX
 SY Max; Myn (mouse); p21.

XX
 OS human, Homo sapiens
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0012; bHLH-ZIP; 1.3.2.2.1.2.
 XX
 SZ 151
AA; 17.2 kDa (cDNA), 21kDa (SDS) [17]
 XX
 XX
 SC edited
SwissProt #P25912
 XX
 FT 2 2 Ser-phosphorylation by CKII
[8].
 FT 3 14 acidic region (7/12).
 FT 11 11 Ser-phosphorylation
by CKII [8].
 FT 15 26 basic region.
 FT 15 66 PF00010;
HLH.
 FT 20 71 SM00353; HLH.
 FT 27 66 helix-loop-helix
domain.
 FT 65 93 leucine zipper (MHL3).
 FT 90 151 replaced
in delta Max by GESES [16].
 FT 140 147 nuclear localization
signal (NLS) [13].
 XX
 SF several splice variants ,
 detected;
 SF Max homodimers and Myc/Max heterodimers
exhibit different preferences for
 SF the trinucleotides flanking
the core sequence (CACGTG) [5];
 SF Max1 and Max2 also differ
slightly in their DNA-binding specificity [5]
 SF [12];

SF heterodimers with either c-Myc or Mad exert higher DNA-binding
affinity
 SF than Max homodimers unless the inhibiting CKII
phosphorylation site is
 SF replaced by alanine [9] [14] [4];

SF heterodimerization requires the leucine zipper, but not homodimerization

SF [13] [20];
 SF DNA-binding by Max or Myc/Max induces bending
towards the minor groove by
 SF 74-82 deg, but possibly in
opposite orientiations [15] [19];
 SF belongs to group B HLH-proteins
that bind to CACGTG motif in DNA [2] which
 SF is due to certain
residues in DNA-binding domain (His at pos. 19, Glu at
 SF
pos. 23, Arg at pos. 27) [2] [1];
 XX
 FF enhances c-Myc
DNA-binding;
 FF in high concentrations: homodimers suppress
c-Myc activities by competition
 FF [13] [16] [6];
 FF after
CKII phosphorylation, increases in on- and off-rates of DNA-binding

FF of homo- and heterodimers have been found [8];
 FF preferentially
complexed with Mad instead of c-Myc upon myeloid
 FF differentiation
[11];
 XX
 IN T00140; c-Myc; human, Homo sapiens.
 IN
T00141; c-Myc; chick, Gallus gallus.
 IN T00142; c-Myc; rat,
Rattus norvegicus.
 IN T00143; c-Myc; mouse, Mus musculus.

IN T01566; deltaMax; human, Homo sapiens.
 IN T02385; L-Myc-1(long
form); human, Homo sapiens.
 IN T02388; L-Myc-1; clawed frog,
Xenopus laevis.
 IN T02389; L-Myc-2; clawed frog, Xenopus laevis.

IN T02387; L-Myc1; mouse, Mus musculus.
 IN T01565; Mad1; human,
Homo sapiens.
 IN T02390; Mad1; mouse, Mus musculus.
 IN
T02391; Mad3; mouse, Mus musculus.
 IN T02392; Mad4; mouse,
Mus musculus.
 IN T00489; Max1; human, Homo sapiens.
 IN
T01564; Mxi1; human, Homo sapiens.
 IN T01445; N-Myc; mouse,
Mus musculus.
 IN T02379; N-Myc; human, Homo sapiens.
 IN
T03268; Rox; human, Homo sapiens.
 XX
 XX
 XX
 XX

RN [1]; RE0017817.
 RX MEDLINE; 20528627.
 RA Billin A.
N., Eilers A. L., Coulter K. L., Logan J. S., Ayer D. E.
 RT
MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional

RT activator that constitutes a positive branch of a max-like
network
 RL Mol. Cell. Biol. 20:8845-8854 (2000).
 RN [2];
RE0017805.
 RX MEDLINE; 99075645.
 RA Meng X., Lu X., Li
Z., Green E. D., Massa H., Trask B. J., Morris C. A.,
 RA Keating
M. T.
 RT Complete physical map of the common deletion region
in Williams syndrome
 RT and identification and characterization
of three novel genes
 RL Hum. Genet. 103:590-599 (1998).

RN [3]; RE0014442.
 RX MEDLINE; 97327566.
 RA Meroni G.,
Reymond A., Alcalay M., Borsani G., Tanigami A., Tonlorenzi R.,

RA Nigro C. L., Messali S., Zollo M., Ledbetter D. H., Brent R.,
Ballabio A.,
 RA Carrozzo R.
 RT Rox, a novel bHLHZip protein
expressed in quiescent cells that
 RT heterodimerizes with
Max, binds a non-canonical E box and acts as a
 RT transcriptional
repressor
 RL EMBO J. 16:2892-2906 (1997).
 RN [4]; RE0005829.

RX MEDLINE; 96081945.
 RA Kohlhuber F., Hermeking H., Graessmann
A., Eick D.
 RT Induction of apoptosis by the c-Myc helix-loop-helix/leucine
zipper domain
 RT in mouse 3T3-L1 fibroblasts
 RL J. Biol.
Chem. 270:28797-28805 (1995).
 RN [5]; RE0002937.
 RX MEDLINE;
94089386.
 RA Solomon D. L. C., Amati B., Land H.
 RT Distinct
DNA binding preferences for the c-Myc/Max and Max/Max dimers

RL Nucleic Acids Res. 21:5372-5376 (1993).
 RN [6]; RE0003361.

RX MEDLINE; 93145325.
 RA Amati B., Brooks M. W., Levy N.,
Littlewood T. D., Evan G. I., Land H.
 RT Oncogenic activity
of the c-Myc protein requires dimerization with Max
 RL Cell
72:233-245 (1993).
 RN [7]; RE0003399.
 RX MEDLINE; 94085381.

RA Fisher F., Crouch D. H., Jayaraman P. S., Clark W., Gillespie
D. A. F.,
 RA Goding C. R.
 RT Transcription activation
by Myc and Max: flanking sequences target
 RT activation to
a subset of CACGTG motifs in vivo
 RL EMBO J. 12:5075-5082
(1993).
 RN [8]; RE0003400.
 RX MEDLINE; 94067769.
 RA
Bousset K., Henriksson M., Luescher-Firzlaff J. M., Litchfield
D. W.,
 RA Luescher B.
 RT Identification of casein kinase
II phosphorylation sites in Max: effects on
 RT DNA-binding
kinetics of Max homo- and Myc/Max heterodimers
 RL Oncogene
8:3211-3220 (1993).
 RN [9]; RE0003401.
 RX MEDLINE; 93145323.

RA Ayer D. E., Kretzner L., Eisenman R. N.
 RT Mad: a heterodimeric
partner for Max that antagonizes Myc transcriptional
 RT activity

RL Cell 72:211-222 (1993).
 RN [10]; RE0003402.
 RX MEDLINE;
93145324.
 RA Zervos A. S., Gyuris J., Brent R.
 RT Mxi1,
a protein that specifically interacts with Max to bind Myc-Max

RT recognition sites
 RL Cell 72:223-232 (1993).
 RN [11];
RE0003403.
 RX MEDLINE; 94040733.
 RA Ayer D. E., Eisenman
R. N.
 RT A switch from Myc:Max to Mad:Max heterocomplexes
accompanies
 RT monocyte/macrophage differentiation
 RL
Genes Dev. 7:2110-2119 (1993).
 RN [12]; RE0003404.
 RX
MEDLINE; 93157390.
 RA Prochownik E. V., Antwerp M. E.

RT Differential patterns of DNA binding by myc and max proteins

RL Proc. Natl. Acad. Sci. USA 90:960-964 (1993).
 RN [13];
RE0000704.
 RX MEDLINE; 92112038.
 RA Kato G. J., Lee W.
M. F., Chen L., Dang C. V.
 RT Max: functional domains and
interaction with c-Myc
 RL Genes Dev. 6:81-92 (1992).
 RN
[14]; RE0000705.
 RX MEDLINE; 92146952.
 RA Berberich S.
J., Cole M. D.
 RT Casein kinase II inhibits the DNA-binding
activity of Max homodimers but
 RT not Myc/Max heterodimers

RL Genes Dev. 6:166-176 (1992).
 RN [15]; RE0003338.
 RX
MEDLINE; 93101610.
 RA Fisher D. E., Parent L. A., Sharp P.
A.
 RT Myc/Max and other helix-loop-helix/leucine zipper proteins
bend DNA toward
 RT the minor groove
 RL Proc. Natl. Acad.
Sci. USA 89:11779-11783 (1992).
 RN [16]; RE0003350.
 RX
MEDLINE; 92229468.
 RA Maekelae T. P., Koskinen P. J., Vaestrik
I., Alitalo K.
 RT Alternative forms of Max as enhancers or
suppressors of Myc-Ras
 RT cotransformation
 RL Science
256:373-377 (1992).
 RN [17]; RE0003353.
 RX MEDLINE; 92112037.

RA Blackwood E. M., Luescher B., Eisenman R. N.
 RT Myc and
Max associate in vivo
 RL Genes Dev. 6:71-80 (1992).
 RN
[18]; RE0003387.
 RX MEDLINE; 92334862.
 RA Min S., Taparowsky
E. J.
 RT v-Myc, but not Max, possesses domains that function
in both transcription
 RT activation and cellular transformation

RL Oncogene 7:1531-1540 (1992).
 RN [19]; RE0003396.
 RX
MEDLINE; 92366516.
 RA Wechsler D. S., Dang C. V.
 RT Opposite
directions of DNA bending by c-Myc and Max
 RL Proc. Natl.
Acad. Sci. USA 89:7635-7639 (1992).
 RN [20]; RE0003397.

RX MEDLINE; 93026389.
 RA Reddy C. D., Dasgupta P., Saikumar
P., Dudek H., Rauscher III F. J., Reddy
 RA E. P.
 RT Mutational
analysis of Max: role of basic, helix-loop-helix/leucine zipper

RT domains in DNA binding, dimerization and regulation of Myc-mediated

RT transcriptional activation
 RL Oncogene 7:2085-2092 (1992).

RN [21]; RE0003398.
 RX MEDLINE; 92212978.
 RA Wagner A.
J., Le Beau M. M., Diaz M. O., Hay N.
 RT Expression, regulation,
and chromosomal localization of the Max gene
 RL Proc. Natl.
Acad. Sci. USA 89:3111-3115 (1992).
 RN [22]; RE0000477.

RX MEDLINE; 92037532.
 RA Wenzel A., Cziepluch C., Hamann U.,
Schuermann J., Schwab M.
 RT The N-Myc oncoprotein is associated
in vivo with the phosphoprotein
 RT Max(p20/22) in human neuroblastoma
cells
 RL EMBO J. 10:3703-3712 (1991).
 RN [23]; RE0002653.

RX MEDLINE; 91173288.
 RA Blackwood E. M., Eisenman R. N.

RT Max: a helix-loop-helix zipper protein that forms a sequence-specific

RT DNA-binding complex with Myc
 RL Science 251:1211-1217 (1991).

XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

269 genes, 269 accessions (Toggle view)

AccessionGeneTitleLinks
LOC147727LOC147727hypothetical protein LOC147727Source|GeneCards
FEN1FEN1flap structure-specific endonuclease 1Source|GeneCards
RUNX2RUNX2runt-related transcription factor 2Source|GeneCards
DKFZP547B139DKFZP547B139hypothetical protein DKFZp547B139Source|GeneCards
GTF2H1GTF2H1general transcription factor IIH, polypeptide 1, 62kDaSource|GeneCards
PDK2PDK2pyruvate dehydrogenase kinase, isoenzyme 2Source|GeneCards
NIP30NIP30NEFA-interacting nuclear protein NIP30Source|GeneCards
FOXD3FOXD3forkhead box D3Source|GeneCards
SSR1SSR1signal sequence receptor, alpha (translocon-associated protein alpha)Source|GeneCards
TOPORSTOPORStopoisomerase I binding, arginine/serine-richSource|GeneCards
FLJ14451ZC3H10zinc finger CCCH-type containing 10Source|GeneCards
FLJ22965FLJ22965hypothetical protein FLJ22965Source|GeneCards
RPS2RPS2ribosomal protein S2Source|GeneCards
CADCADcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotaseSource|GeneCards
BCAS3BCAS3breast carcinoma amplified sequence 3Source|GeneCards
DD5EDD1E3 ubiquitin protein ligase, HECT domain containing, 1Source|GeneCards
LOC138046LOC138046hypothetical protein LOC138046Source|GeneCards
ZNF318ZNF318zinc finger protein 318Source|GeneCards
KIAA1737KIAA1737KIAA1737Source|GeneCards
TOP1TOP1topoisomerase (DNA) ISource|GeneCards
GPX1GPX1glutathione peroxidase 1Source|GeneCards
NFX1NFX1nuclear transcription factor, X-box binding 1Source|GeneCards
PLCG2PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific)Source|GeneCards
CGI-72PHF20L1PHD finger protein 20-like 1Source|GeneCards
SUPT16HSUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae)Source|GeneCards
C6ORF96C6ORF96chromosome 6 open reading frame 96Source|GeneCards
AKAP1AKAP1A kinase (PRKA) anchor protein 1Source|GeneCards
ILF3ILF3interleukin enhancer binding factor 3, 90kDaSource|GeneCards
C9ORF84C9ORF84chromosome 9 open reading frame 84Source|GeneCards
SLC38A2SLC38A2solute carrier family 38, member 2Source|GeneCards
MXD4MXD4MAX dimerization protein 4Source|GeneCards
CPEB4CPEB4cytoplasmic polyadenylation element binding protein 4Source|GeneCards
TESK2TESK2testis-specific kinase 2Source|GeneCards
LIN28LIN28lin-28 homolog (C. elegans)Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
GATA5GATA5GATA binding protein 5Source|GeneCards
D1S155ECSDE1cold shock domain containing E1, RNA-bindingSource|GeneCards
COMMD3COMMD3COMM domain containing 3Source|GeneCards
MJDATXN3ataxin 3Source|GeneCards
AATFAATFapoptosis antagonizing transcription factorSource|GeneCards
FKBP11FKBP11FK506 binding protein 11, 19 kDaSource|GeneCards
SNX5SNX5sorting nexin 5Source|GeneCards
MRPL40MRPL40mitochondrial ribosomal protein L40Source|GeneCards
ELAVL3ELAVL3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)Source|GeneCards
LOC90701LOC90701similar to signal peptidase complex (18kD)Source|GeneCards
PPRC1PPRC1peroxisome proliferative activated receptor, gamma, coactivator-related 1Source|GeneCards
DKFZP434N1235SLC25A31solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31Source|GeneCards
XPO1XPO1exportin 1 (CRM1 homolog, yeast)Source|GeneCards
FLJ34969FLJ34969hypothetical protein FLJ34969Source|GeneCards
CBX5CBX5chromobox homolog 5 (HP1 alpha homolog, Drosophila)Source|GeneCards
QTRT1QTRT1queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)Source|GeneCards
VGFVGFVGF nerve growth factor inducibleSource|GeneCards
TIMM10TIMM10translocase of inner mitochondrial membrane 10 homolog (yeast)Source|GeneCards
PRPS1PRPS1phosphoribosyl pyrophosphate synthetase 1Source|GeneCards
NIT1NIT1nitrilase 1Source|GeneCards
PRO0149PRO0149PRO0149 proteinSource|GeneCards
RBAF600RBAF600retinoblastoma-associated factor 600Source|GeneCards
MRPL27MRPL27mitochondrial ribosomal protein L27Source|GeneCards
TIEG2KLF11Kruppel-like factor 11Source|GeneCards
MGC13272MON1AMON1 homolog A (yeast)Source|GeneCards
DUSP7DUSP7dual specificity phosphatase 7Source|GeneCards
TCF4TCF4Transcription factor 4Source|GeneCards
ATP6V1C1ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1Source|GeneCards
PABPC1PABPC1poly(A) binding protein, cytoplasmic 1Source|GeneCards
HIRAHIRAHIR histone cell cycle regulation defective homolog A (S. cerevisiae)Source|GeneCards
HMGA1HMGA1high mobility group AT-hook 1Source|GeneCards
CSPG6CSPG6chondroitin sulfate proteoglycan 6 (bamacan)Source|GeneCards
TGFB2TGFB2transforming growth factor, beta 2Source|GeneCards
PAI-RBP1SERBP1SERPINE1 mRNA binding protein 1Source|GeneCards
ANKHD1ANKHD1Eukaryotic translation initiation factor 4E binding protein 3Source|GeneCards
HOXC5HOXC5homeo box C5Source|GeneCards
FLJ32549FLJ32549hypothetical protein FLJ32549Source|GeneCards
CHD4CHD4chromodomain helicase DNA binding protein 4Source|GeneCards
HOXD10HOXD10homeo box D10Source|GeneCards
HHEXHHEXhematopoietically expressed homeoboxSource|GeneCards
IPO13IPO13importin 13Source|GeneCards
NOTCH1NOTCH1Notch homolog 1, translocation-associated (Drosophila)Source|GeneCards
MGC35261CXORF41chromosome X open reading frame 41Source|GeneCards
ETV1ETV1ets variant gene 1Source|GeneCards
EPC1EPC1enhancer of polycomb homolog 1, (Drosophila)Source|GeneCards
BRDTBRDTbromodomain, testis-specificSource|GeneCards
BMP6BMP6bone morphogenetic protein 6Source|GeneCards
MEOX2MEOX2mesenchyme homeo box 2 (growth arrest-specific homeo box)Source|GeneCards
MGC4655MGC4655hypothetical protein MGC4655Source|GeneCards
UBE4BUBE4Bubiquitination factor E4B (UFD2 homolog, yeast)Source|GeneCards
DSCAMDSCAMDown syndrome cell adhesion moleculeSource|GeneCards
GNB2GNB2guanine nucleotide binding protein (G protein), beta polypeptide 2Source|GeneCards
SEPT3SEPT3septin 3Source|GeneCards
MGC4268MGC4268hypothetical protein MGC4268Source|GeneCards
BOKBOKBCL2-related ovarian killerSource|GeneCards
UBE2BUBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)Source|GeneCards
PTMAPTMAprothymosin, alpha (gene sequence 28)Source|GeneCards
KCNE4KCNE4potassium voltage-gated channel, Isk-related family, member 4Source|GeneCards
FLJ43965CCDC4coiled-coil domain containing 4Source|GeneCards
DDX3XDDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linkedSource|GeneCards
ZBTB10ZBTB10Zinc finger and BTB domain containing 10Source|GeneCards
AKAP12AKAP12A kinase (PRKA) anchor protein (gravin) 12Source|GeneCards
C10ORF46C10ORF46chromosome 10 open reading frame 46Source|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
VPS16VPS16vacuolar protein sorting 16 (yeast)Source|GeneCards
OGDHLOGDHLoxoglutarate dehydrogenase-likeSource|GeneCards
MAXMAXMAX proteinSource|GeneCards
C20ORF112C20ORF112chromosome 20 open reading frame 112Source|GeneCards
SNTB2SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)Source|GeneCards
HNRPA1HNRPA1heterogeneous nuclear ribonucleoprotein A1Source|GeneCards
TCERG1TCERG1transcription elongation regulator 1 (CA150)Source|GeneCards
NDUFS1NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)Source|GeneCards
SPINLSPINLspinster-likeSource|GeneCards
C6ORF211C6ORF211chromosome 6 open reading frame 211Source|GeneCards
LOC91614LOC91614novel 58.3 KDA proteinSource|GeneCards
EIF4EEIF4Eeukaryotic translation initiation factor 4ESource|GeneCards
CCAR1CCAR1cell division cycle and apoptosis regulator 1Source|GeneCards
BAXBAXBCL2-associated X proteinSource|GeneCards
MAP1DMAP1Dmethionine aminopeptidase 1DSource|GeneCards
GGNGGNgametogenetinSource|GeneCards
FOXO3AFOXO3Aforkhead box O3ASource|GeneCards
DVL2DVL2dishevelled, dsh homolog 2 (Drosophila)Source|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
C20ORF72C20ORF72chromosome 20 open reading frame 72Source|GeneCards
RAB3IL1RAB3IL1RAB3A interacting protein (rabin3)-like 1Source|GeneCards
PPP1R3CPPP1R3Cprotein phosphatase 1, regulatory (inhibitor) subunit 3CSource|GeneCards
NEUROD1NEUROD1neurogenic differentiation 1Source|GeneCards
CFL1CFL1cofilin 1 (non-muscle)Source|GeneCards
CENTB5CENTB5centaurin, beta 5Source|GeneCards
GAPDGAPDglyceraldehyde-3-phosphate dehydrogenaseSource|GeneCards
ANAPC13ANAPC13anaphase promoting complex subunit 13Source|GeneCards
BTBD5BTBD5BTB (POZ) domain containing 5Source|GeneCards
PER1PER1period homolog 1 (Drosophila)Source|GeneCards
MGC13053MGC13053hypothetical protein MGC13053Source|GeneCards
KBTBD2KBTBD2kelch repeat and BTB (POZ) domain containing 2Source|GeneCards
EEF1B2EEF1B2eukaryotic translation elongation factor 1 beta 2Source|GeneCards
NPM1NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)Source|GeneCards
ADSSADSSadenylosuccinate synthaseSource|GeneCards
IMP-1IMP-1IGF-II mRNA-binding protein 1Source|GeneCards
HUMAGCGBRBM15BRNA binding motif protein 15BSource|GeneCards
ATF4ATF4activating transcription factor 4 (tax-responsive enhancer element B67)Source|GeneCards
EN1EN1engrailed homolog 1Source|GeneCards
POGKPOGKpogo transposable element with KRAB domainSource|GeneCards
HOXB5HOXB5homeo box B5Source|GeneCards
KIAA1407KIAA1407KIAA1407 proteinSource|GeneCards
EME1EME1essential meiotic endonuclease 1 homolog 1 (S. pombe)Source|GeneCards
SIRT1SIRT1sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)Source|GeneCards
CPT1ACPT1Acarnitine palmitoyltransferase 1A (liver)Source|GeneCards
FLJ13386FLJ13386hypothetical protein FLJ13386Source|GeneCards
PA2G4PA2G4proliferation-associated 2G4, 38kDaSource|GeneCards
OPRS1OPRS1opioid receptor, sigma 1Source|GeneCards
ZNF503ZNF503zinc finger protein 503Source|GeneCards
THUMPD2THUMPD2THUMP domain containing 2Source|GeneCards
C22ORF14DERL3Der1-like domain family, member 3Source|GeneCards
FLJ23861FLJ23861hypothetical protein FLJ23861Source|GeneCards
USP15USP15ubiquitin specific protease 15Source|GeneCards
AMPD2AMPD2adenosine monophosphate deaminase 2 (isoform L)Source|GeneCards
DKFZP564O0463WDSOF1WD repeats and SOF1 domain containingSource|GeneCards
NUDCNUDCnuclear distribution gene C homolog (A. nidulans)Source|GeneCards
ACY1ACY1aminoacylase 1Source|GeneCards
HPS5HPS5Hermansky-Pudlak syndrome 5Source|GeneCards
C11ORF10C11ORF10chromosome 11 open reading frame 10Source|GeneCards
EIF3S10EIF3S10eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDaSource|GeneCards
MGEA6CTAGE5CTAGE family, member 5Source|GeneCards
FLJ20071DYMDymeclinSource|GeneCards
PTGES2PTGES2prostaglandin E synthase 2Source|GeneCards
GJA1GJA1gap junction protein, alpha 1, 43kDa (connexin 43)Source|GeneCards
TCOF1TCOF1Treacher Collins-Franceschetti syndrome 1Source|GeneCards
EPB41EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)Source|GeneCards
AP1S2AP1S2adaptor-related protein complex 1, sigma 2 subunitSource|GeneCards
ZFYVE26ZFYVE26zinc finger, FYVE domain containing 26Source|GeneCards
RLFRLFRearranged L-myc fusionSource|GeneCards
FLJ12750VPS37Bvacuolar protein sorting 37B (yeast)Source|GeneCards
KIAA1972KIAA1972KIAA1972 proteinSource|GeneCards
MTCH2MTCH2mitochondrial carrier homolog 2 (C. elegans)Source|GeneCards
ZCCHC7ZCCHC7zinc finger, CCHC domain containing 7Source|GeneCards
ANKRD12ANKRD12ankyrin repeat domain 12Source|GeneCards
C20ORF81C20ORF81chromosome 20 open reading frame 81Source|GeneCards
ATOH8ATOH8Atonal homolog 8 (Drosophila)Source|GeneCards
PRKCHPRKCHprotein kinase C, etaSource|GeneCards
PSME3PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)Source|GeneCards
ADAMTS17ADAMTS17a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17Source|GeneCards
SLC1A7SLC1A7solute carrier family 1 (glutamate transporter), member 7Source|GeneCards
TUBA1TUBA1tubulin, alpha 1 (testis specific)Source|GeneCards
MTHFD1MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetaseSource|GeneCards
QTRTD1QTRTD1queuine tRNA-ribosyltransferase domain containing 1Source|GeneCards
ATP6V1AATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit ASource|GeneCards
FGF14FGF14fibroblast growth factor 14Source|GeneCards
EIF2C2EIF2C2eukaryotic translation initiation factor 2C, 2Source|GeneCards
TAF6LTAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDaSource|GeneCards
ALDH6A1ALDH6A1aldehyde dehydrogenase 6 family, member A1Source|GeneCards
FLJ40432FLJ40432hypothetical protein FLJ40432Source|GeneCards
PCDHA10PCDHA10protocadherin alpha 10Source|GeneCards
C20ORF104PHF20PHD finger protein 20Source|GeneCards
PRKCGPRKCGprotein kinase C, gammaSource|GeneCards
ARMETARMETarginine-rich, mutated in early stage tumorsSource|GeneCards
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)Source|GeneCards
TUBA4TUBA4tubulin, alpha 4Source|GeneCards
SLC31A2SLC31A2solute carrier family 31 (copper transporters), member 2Source|GeneCards
KIAA0423KIAA0423KIAA0423Source|GeneCards
SNFTSNFTJun dimerization protein p21SNFTSource|GeneCards
ODC1ODC1ornithine decarboxylase 1Source|GeneCards
RCL1RCL1RNA terminal phosphate cyclase-like 1Source|GeneCards
MAT2AMAT2Amethionine adenosyltransferase II, alphaSource|GeneCards
SLC26A2SLC26A2solute carrier family 26 (sulfate transporter), member 2Source|GeneCards
PRDM4PRDM4PR domain containing 4Source|GeneCards
OPRD1OPRD1opioid receptor, delta 1Source|GeneCards
TIMM8ATIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast)Source|GeneCards
BCORBCORBCL6 co-repressorSource|GeneCards
ADAMTS3ADAMTS3a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3Source|GeneCards
CSKCSKc-src tyrosine kinaseSource|GeneCards
PEPP3PLEKHA6pleckstrin homology domain containing, family A member 6Source|GeneCards
SUMF1SUMF1sulfatase modifying factor 1Source|GeneCards
MLLMLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
GIT1GIT1G protein-coupled receptor kinase-interactor 1Source|GeneCards
LAMP1LAMP1lysosomal-associated membrane protein 1Source|GeneCards
ERP70PDIA4protein disulfide isomerase family A, member 4Source|GeneCards
DNAJB5DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5Source|GeneCards
SMAD2SMAD2SMAD, mothers against DPP homolog 2 (Drosophila)Source|GeneCards
FLJ37794FLJ37794hypothetical protein FLJ37794Source|GeneCards
ATF7IPATF7IPactivating transcription factor 7 interacting proteinSource|GeneCards
LZTFL1LZTFL1leucine zipper transcription factor-like 1Source|GeneCards
HOXC11HOXC11homeo box C11Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
SRP72SRP72signal recognition particle 72kDaSource|GeneCards
SCRT2SCRT2scratch homolog 2, zinc finger protein (Drosophila)Source|GeneCards
PPM1APPM1Aprotein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoformSource|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
DKFZP566E144REXO2REX2, RNA exonuclease 2 homolog (S. cerevisiae)Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
DHX35DHX35DEAH (Asp-Glu-Ala-His) box polypeptide 35Source|GeneCards
SNCAIPSNCAIPsynuclein, alpha interacting protein (synphilin)Source|GeneCards
SUCLG2SUCLG2succinate-CoA ligase, GDP-forming, beta subunitSource|GeneCards
TFRCTFRCtransferrin receptor (p90, CD71)Source|GeneCards
DZIP1DZIP1DAZ interacting protein 1Source|GeneCards
MASK-BP3MASK-BP3MASK-4E-BP3 alternate reading frame geneSource|GeneCards
RNF127RNF127ring finger protein 127Source|GeneCards
GUCY1A2GUCY1A2guanylate cyclase 1, soluble, alpha 2Source|GeneCards
CYP2D6CYP2D6cytochrome P450, family 2, subfamily D, polypeptide 6Source|GeneCards
FLJ20130FLJ20130hypothetical protein FLJ20130Source|GeneCards
MGC3040MGC3040hypothetical protein MGC3040Source|GeneCards
CLN3CLN3ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)Source|GeneCards
KCNH4KCNH4potassium voltage-gated channel, subfamily H (eag-related), member 4Source|GeneCards
N-PACN-PACcytokine-like nuclear factor n-pacSource|GeneCards
EIF4BEIF4Beukaryotic translation initiation factor 4BSource|GeneCards
SYT3SYT3synaptotagmin IIISource|GeneCards
ISGF3GISGF3Ginterferon-stimulated transcription factor 3, gamma 48kDaSource|GeneCards
CD164CD164CD164 antigen, sialomucinSource|GeneCards
IQGAP2IQGAP2IQ motif containing GTPase activating protein 2Source|GeneCards
MAK3MAK3Mak3 homolog (S. cerevisiae)Source|GeneCards
PICALMPICALMphosphatidylinositol binding clathrin assembly proteinSource|GeneCards
LOC90668LOC90668hypothetical protein BC008134Source|GeneCards
DUSP1DUSP1dual specificity phosphatase 1Source|GeneCards
EPB41L4BEPB41L4Berythrocyte membrane protein band 4.1 like 4BSource|GeneCards
NICE-3C1ORF43chromosome 1 open reading frame 43Source|GeneCards
SLC38A5SLC38A5solute carrier family 38, member 5Source|GeneCards
RAI14RAI14retinoic acid induced 14Source|GeneCards
NRIP3NRIP3nuclear receptor interacting protein 3Source|GeneCards
HOXA7HOXA7homeo box A7Source|GeneCards
IRS4IRS4insulin receptor substrate 4Source|GeneCards
NOP5/NOP58NOP5/NOP58nucleolar protein NOP5/NOP58Source|GeneCards
NPTX1NPTX1neuronal pentraxin ISource|GeneCards
NMNAT2NMNAT2nicotinamide nucleotide adenylyltransferase 2Source|GeneCards
PFDN2PFDN2prefoldin 2Source|GeneCards
HBP1HBP1HMG-box transcription factor 1Source|GeneCards
COPZ1COPZ1coatomer protein complex, subunit zeta 1Source|GeneCards
STMN1STMN1stathmin 1/oncoprotein 18Source|GeneCards
MFTCSLC25A32solute carrier family 25, member 32Source|GeneCards
DNMT3ADNMT3ADNA (cytosine-5-)-methyltransferase 3 alphaSource|GeneCards
GNASGNASGNAS complex locusSource|GeneCards
ASNA1ASNA1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)Source|GeneCards
FLJ21918RBM35BRNA binding motif protein 35BSource|GeneCards
FGF6FGF6fibroblast growth factor 6Source|GeneCards

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