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Gene set: V$MYCMAX_02 (C3:TFAC:0074)
Standard nameV$MYCMAX_02
Systematic nameC3:TFAC:0074
Brief descriptionGenes with 3'UTR containing motif NANCACGTGNNW which matches annotation for MYC: V-myc myelocytomatosis viral oncogene homolog (avian)
MAX: MAX protein
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA Max1
 XX
 SY Max; Myn (mouse); p21.

XX
 OS human, Homo sapiens
 OC eukaryota; animalia; metazoa;
chordata; vertebrata; tetrapoda; mammalia;
 OC eutheria; primates

XX
 XX
 CL C0012; bHLH-ZIP; 1.3.2.2.1.2.
 XX
 SZ 151
AA; 17.2 kDa (cDNA), 21kDa (SDS) [17]
 XX
 XX
 SC edited
SwissProt #P25912
 XX
 FT 2 2 Ser-phosphorylation by CKII
[8].
 FT 3 14 acidic region (7/12).
 FT 11 11 Ser-phosphorylation
by CKII [8].
 FT 15 26 basic region.
 FT 15 66 PF00010;
HLH.
 FT 20 71 SM00353; HLH.
 FT 27 66 helix-loop-helix
domain.
 FT 65 93 leucine zipper (MHL3).
 FT 90 151 replaced
in delta Max by GESES [16].
 FT 140 147 nuclear localization
signal (NLS) [13].
 XX
 SF several splice variants ,
 detected;
 SF Max homodimers and Myc/Max heterodimers
exhibit different preferences for
 SF the trinucleotides flanking
the core sequence (CACGTG) [5];
 SF Max1 and Max2 also differ
slightly in their DNA-binding specificity [5]
 SF [12];

SF heterodimers with either c-Myc or Mad exert higher DNA-binding
affinity
 SF than Max homodimers unless the inhibiting CKII
phosphorylation site is
 SF replaced by alanine [9] [14] [4];

SF heterodimerization requires the leucine zipper, but not homodimerization

SF [13] [20];
 SF DNA-binding by Max or Myc/Max induces bending
towards the minor groove by
 SF 74-82 deg, but possibly in
opposite orientiations [15] [19];
 SF belongs to group B HLH-proteins
that bind to CACGTG motif in DNA [2] which
 SF is due to certain
residues in DNA-binding domain (His at pos. 19, Glu at
 SF
pos. 23, Arg at pos. 27) [2] [1];
 XX
 FF enhances c-Myc
DNA-binding;
 FF in high concentrations: homodimers suppress
c-Myc activities by competition
 FF [13] [16] [6];
 FF after
CKII phosphorylation, increases in on- and off-rates of DNA-binding

FF of homo- and heterodimers have been found [8];
 FF preferentially
complexed with Mad instead of c-Myc upon myeloid
 FF differentiation
[11];
 XX
 IN T00140; c-Myc; human, Homo sapiens.
 IN
T00141; c-Myc; chick, Gallus gallus.
 IN T00142; c-Myc; rat,
Rattus norvegicus.
 IN T00143; c-Myc; mouse, Mus musculus.

IN T01566; deltaMax; human, Homo sapiens.
 IN T02385; L-Myc-1(long
form); human, Homo sapiens.
 IN T02388; L-Myc-1; clawed frog,
Xenopus laevis.
 IN T02389; L-Myc-2; clawed frog, Xenopus laevis.

IN T02387; L-Myc1; mouse, Mus musculus.
 IN T01565; Mad1; human,
Homo sapiens.
 IN T02390; Mad1; mouse, Mus musculus.
 IN
T02391; Mad3; mouse, Mus musculus.
 IN T02392; Mad4; mouse,
Mus musculus.
 IN T00489; Max1; human, Homo sapiens.
 IN
T01564; Mxi1; human, Homo sapiens.
 IN T01445; N-Myc; mouse,
Mus musculus.
 IN T02379; N-Myc; human, Homo sapiens.
 IN
T03268; Rox; human, Homo sapiens.
 XX
 XX
 XX
 XX

RN [1]; RE0017817.
 RX MEDLINE; 20528627.
 RA Billin A.
N., Eilers A. L., Coulter K. L., Logan J. S., Ayer D. E.
 RT
MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional

RT activator that constitutes a positive branch of a max-like
network
 RL Mol. Cell. Biol. 20:8845-8854 (2000).
 RN [2];
RE0017805.
 RX MEDLINE; 99075645.
 RA Meng X., Lu X., Li
Z., Green E. D., Massa H., Trask B. J., Morris C. A.,
 RA Keating
M. T.
 RT Complete physical map of the common deletion region
in Williams syndrome
 RT and identification and characterization
of three novel genes
 RL Hum. Genet. 103:590-599 (1998).

RN [3]; RE0014442.
 RX MEDLINE; 97327566.
 RA Meroni G.,
Reymond A., Alcalay M., Borsani G., Tanigami A., Tonlorenzi R.,

RA Nigro C. L., Messali S., Zollo M., Ledbetter D. H., Brent R.,
Ballabio A.,
 RA Carrozzo R.
 RT Rox, a novel bHLHZip protein
expressed in quiescent cells that
 RT heterodimerizes with
Max, binds a non-canonical E box and acts as a
 RT transcriptional
repressor
 RL EMBO J. 16:2892-2906 (1997).
 RN [4]; RE0005829.

RX MEDLINE; 96081945.
 RA Kohlhuber F., Hermeking H., Graessmann
A., Eick D.
 RT Induction of apoptosis by the c-Myc helix-loop-helix/leucine
zipper domain
 RT in mouse 3T3-L1 fibroblasts
 RL J. Biol.
Chem. 270:28797-28805 (1995).
 RN [5]; RE0002937.
 RX MEDLINE;
94089386.
 RA Solomon D. L. C., Amati B., Land H.
 RT Distinct
DNA binding preferences for the c-Myc/Max and Max/Max dimers

RL Nucleic Acids Res. 21:5372-5376 (1993).
 RN [6]; RE0003361.

RX MEDLINE; 93145325.
 RA Amati B., Brooks M. W., Levy N.,
Littlewood T. D., Evan G. I., Land H.
 RT Oncogenic activity
of the c-Myc protein requires dimerization with Max
 RL Cell
72:233-245 (1993).
 RN [7]; RE0003399.
 RX MEDLINE; 94085381.

RA Fisher F., Crouch D. H., Jayaraman P. S., Clark W., Gillespie
D. A. F.,
 RA Goding C. R.
 RT Transcription activation
by Myc and Max: flanking sequences target
 RT activation to
a subset of CACGTG motifs in vivo
 RL EMBO J. 12:5075-5082
(1993).
 RN [8]; RE0003400.
 RX MEDLINE; 94067769.
 RA
Bousset K., Henriksson M., Luescher-Firzlaff J. M., Litchfield
D. W.,
 RA Luescher B.
 RT Identification of casein kinase
II phosphorylation sites in Max: effects on
 RT DNA-binding
kinetics of Max homo- and Myc/Max heterodimers
 RL Oncogene
8:3211-3220 (1993).
 RN [9]; RE0003401.
 RX MEDLINE; 93145323.

RA Ayer D. E., Kretzner L., Eisenman R. N.
 RT Mad: a heterodimeric
partner for Max that antagonizes Myc transcriptional
 RT activity

RL Cell 72:211-222 (1993).
 RN [10]; RE0003402.
 RX MEDLINE;
93145324.
 RA Zervos A. S., Gyuris J., Brent R.
 RT Mxi1,
a protein that specifically interacts with Max to bind Myc-Max

RT recognition sites
 RL Cell 72:223-232 (1993).
 RN [11];
RE0003403.
 RX MEDLINE; 94040733.
 RA Ayer D. E., Eisenman
R. N.
 RT A switch from Myc:Max to Mad:Max heterocomplexes
accompanies
 RT monocyte/macrophage differentiation
 RL
Genes Dev. 7:2110-2119 (1993).
 RN [12]; RE0003404.
 RX
MEDLINE; 93157390.
 RA Prochownik E. V., Antwerp M. E.

RT Differential patterns of DNA binding by myc and max proteins

RL Proc. Natl. Acad. Sci. USA 90:960-964 (1993).
 RN [13];
RE0000704.
 RX MEDLINE; 92112038.
 RA Kato G. J., Lee W.
M. F., Chen L., Dang C. V.
 RT Max: functional domains and
interaction with c-Myc
 RL Genes Dev. 6:81-92 (1992).
 RN
[14]; RE0000705.
 RX MEDLINE; 92146952.
 RA Berberich S.
J., Cole M. D.
 RT Casein kinase II inhibits the DNA-binding
activity of Max homodimers but
 RT not Myc/Max heterodimers

RL Genes Dev. 6:166-176 (1992).
 RN [15]; RE0003338.
 RX
MEDLINE; 93101610.
 RA Fisher D. E., Parent L. A., Sharp P.
A.
 RT Myc/Max and other helix-loop-helix/leucine zipper proteins
bend DNA toward
 RT the minor groove
 RL Proc. Natl. Acad.
Sci. USA 89:11779-11783 (1992).
 RN [16]; RE0003350.
 RX
MEDLINE; 92229468.
 RA Maekelae T. P., Koskinen P. J., Vaestrik
I., Alitalo K.
 RT Alternative forms of Max as enhancers or
suppressors of Myc-Ras
 RT cotransformation
 RL Science
256:373-377 (1992).
 RN [17]; RE0003353.
 RX MEDLINE; 92112037.

RA Blackwood E. M., Luescher B., Eisenman R. N.
 RT Myc and
Max associate in vivo
 RL Genes Dev. 6:71-80 (1992).
 RN
[18]; RE0003387.
 RX MEDLINE; 92334862.
 RA Min S., Taparowsky
E. J.
 RT v-Myc, but not Max, possesses domains that function
in both transcription
 RT activation and cellular transformation

RL Oncogene 7:1531-1540 (1992).
 RN [19]; RE0003396.
 RX
MEDLINE; 92366516.
 RA Wechsler D. S., Dang C. V.
 RT Opposite
directions of DNA bending by c-Myc and Max
 RL Proc. Natl.
Acad. Sci. USA 89:7635-7639 (1992).
 RN [20]; RE0003397.

RX MEDLINE; 93026389.
 RA Reddy C. D., Dasgupta P., Saikumar
P., Dudek H., Rauscher III F. J., Reddy
 RA E. P.
 RT Mutational
analysis of Max: role of basic, helix-loop-helix/leucine zipper

RT domains in DNA binding, dimerization and regulation of Myc-mediated

RT transcriptional activation
 RL Oncogene 7:2085-2092 (1992).

RN [21]; RE0003398.
 RX MEDLINE; 92212978.
 RA Wagner A.
J., Le Beau M. M., Diaz M. O., Hay N.
 RT Expression, regulation,
and chromosomal localization of the Max gene
 RL Proc. Natl.
Acad. Sci. USA 89:3111-3115 (1992).
 RN [22]; RE0000477.

RX MEDLINE; 92037532.
 RA Wenzel A., Cziepluch C., Hamann U.,
Schuermann J., Schwab M.
 RT The N-Myc oncoprotein is associated
in vivo with the phosphoprotein
 RT Max(p20/22) in human neuroblastoma
cells
 RL EMBO J. 10:3703-3712 (1991).
 RN [23]; RE0002653.

RX MEDLINE; 91173288.
 RA Blackwood E. M., Eisenman R. N.

RT Max: a helix-loop-helix zipper protein that forms a sequence-specific

RT DNA-binding complex with Myc
 RL Science 251:1211-1217 (1991).

XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

275 genes, 275 accessions (Toggle view)

AccessionGeneTitleLinks
RUNX2RUNX2runt-related transcription factor 2Source|GeneCards
H3F3BH3F3BH3 histone, family 3B (H3.3B)Source|GeneCards
CXORF15CXORF15chromosome X open reading frame 15Source|GeneCards
NIP30NIP30NEFA-interacting nuclear protein NIP30Source|GeneCards
LOC124842LOC124842hypothetical protein LOC124842Source|GeneCards
OGNOGNosteoglycin (osteoinductive factor, mimecan)Source|GeneCards
ODZ1ODZ1odz, odd Oz/ten-m homolog 1(Drosophila)Source|GeneCards
MKRN3MKRN3makorin, ring finger protein, 3Source|GeneCards
FLJ14451ZC3H10zinc finger CCCH-type containing 10Source|GeneCards
GPR65GPR65G protein-coupled receptor 65Source|GeneCards
GPC3GPC3glypican 3Source|GeneCards
RPS2RPS2ribosomal protein S2Source|GeneCards
CADCADcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotaseSource|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
MAML3MAML3Mastermind-like 3 (Drosophila)Source|GeneCards
FRMD4FRMD4AFERM domain containing 4ASource|GeneCards
CDK2CDK2cyclin-dependent kinase 2Source|GeneCards
MGC8407CAMKVCaM kinase-like vesicle-associatedSource|GeneCards
DCTDCTdopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)Source|GeneCards
TOP1TOP1topoisomerase (DNA) ISource|GeneCards
SOX12SOX12SRY (sex determining region Y)-box 12Source|GeneCards
FLJ13096FLJ13096hypothetical protein FLJ13096Source|GeneCards
TYRTYRtyrosinase (oculocutaneous albinism IA)Source|GeneCards
HNRPDLHNRPDLheterogeneous nuclear ribonucleoprotein D-likeSource|GeneCards
IHPK1IHPK1inositol hexaphosphate kinase 1Source|GeneCards
TESK2TESK2testis-specific kinase 2Source|GeneCards
UBXD3UBXD3UBX domain containing 3Source|GeneCards
LIN28LIN28lin-28 homolog (C. elegans)Source|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
COMMD3COMMD3COMM domain containing 3Source|GeneCards
PPRC1PPRC1peroxisome proliferative activated receptor, gamma, coactivator-related 1Source|GeneCards
ADD3ADD3adducin 3 (gamma)Source|GeneCards
FLJ44815FLJ44815FLJ44815 proteinSource|GeneCards
JADE1PHF17PHD finger protein 17Source|GeneCards
FKBP5FKBP5FK506 binding protein 5Source|GeneCards
CBARA1CBARA1calcium binding atopy-related autoantigen 1Source|GeneCards
MGC35555RSPO2R-spondin 2 homolog (Xenopus laevis)Source|GeneCards
H2AFZH2AFZH2A histone family, member ZSource|GeneCards
XPO1XPO1exportin 1 (CRM1 homolog, yeast)Source|GeneCards
CBX5CBX5chromobox homolog 5 (HP1 alpha homolog, Drosophila)Source|GeneCards
VGFVGFVGF nerve growth factor inducibleSource|GeneCards
TIMM10TIMM10translocase of inner mitochondrial membrane 10 homolog (yeast)Source|GeneCards
LPXNLPXNleupaxinSource|GeneCards
HRMT1L2HRMT1L2HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)Source|GeneCards
WFIKKNRPWFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2Source|GeneCards
NEUROD2NEUROD2neurogenic differentiation 2Source|GeneCards
GATA4GATA4GATA binding protein 4Source|GeneCards
RBAF600RBAF600retinoblastoma-associated factor 600Source|GeneCards
GALNT4GALNT4UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)Source|GeneCards
MIST1BHLHB8basic helix-loop-helix domain containing, class B, 8Source|GeneCards
FBXW7FBXW7F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)Source|GeneCards
TCF4TCF4Transcription factor 4Source|GeneCards
CALB2CALB2calbindin 2, 29kDa (calretinin)Source|GeneCards
UVRAGUVRAGUV radiation resistance associated geneSource|GeneCards
PLAG1PLAG1pleiomorphic adenoma gene 1Source|GeneCards
C13ORF7C13ORF7chromosome 13 open reading frame 7Source|GeneCards
PAI-RBP1SERBP1SERPINE1 mRNA binding protein 1Source|GeneCards
TGFB2TGFB2transforming growth factor, beta 2Source|GeneCards
ANKHD1ANKHD1Eukaryotic translation initiation factor 4E binding protein 3Source|GeneCards
HSPH1HSPH1heat shock 105kDa/110kDa protein 1Source|GeneCards
FLJ32549FLJ32549hypothetical protein FLJ32549Source|GeneCards
HOXD10HOXD10homeo box D10Source|GeneCards
USP34USP34ubiquitin specific protease 34Source|GeneCards
IPO13IPO13importin 13Source|GeneCards
MGC35261CXORF41chromosome X open reading frame 41Source|GeneCards
NOTCH1NOTCH1Notch homolog 1, translocation-associated (Drosophila)Source|GeneCards
ETV1ETV1ets variant gene 1Source|GeneCards
C1QTNF5C1QTNF5C1q and tumor necrosis factor related protein 5Source|GeneCards
ZNF342ZNF342zinc finger protein 342Source|GeneCards
TUWD12WDR51BWD repeat domain 51BSource|GeneCards
PTCHPTCHpatched homolog (Drosophila)Source|GeneCards
MGC5508MGC5508hypothetical protein MGC5508Source|GeneCards
DSCAMDSCAMDown syndrome cell adhesion moleculeSource|GeneCards
DBPDBPD site of albumin promoter (albumin D-box) binding proteinSource|GeneCards
GLS2GLS2glutaminase 2 (liver, mitochondrial)Source|GeneCards
SEPT3SEPT3septin 3Source|GeneCards
BOKBOKBCL2-related ovarian killerSource|GeneCards
UBE2BUBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)Source|GeneCards
PTMAPTMAprothymosin, alpha (gene sequence 28)Source|GeneCards
CD2CD2CD2 antigen (p50), sheep red blood cell receptorSource|GeneCards
POLR3EPOLR3Epolymerase (RNA) III (DNA directed) polypeptide E (80kD)Source|GeneCards
FLJ43965CCDC4coiled-coil domain containing 4Source|GeneCards
ANGPT2ANGPT2angiopoietin 2Source|GeneCards
HIF1AHIF1Ahypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Source|GeneCards
BCL9LBCL9LB-cell CLL/lymphoma 9-likeSource|GeneCards
BACH1BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1Source|GeneCards
DLX1DLX1distal-less homeo box 1Source|GeneCards
RTN4RL2RTN4RL2reticulon 4 receptor-like 2Source|GeneCards
FXR1FXR1fragile X mental retardation, autosomal homolog 1Source|GeneCards
C10ORF46C10ORF46chromosome 10 open reading frame 46Source|GeneCards
FOXF2FOXF2forkhead box F2Source|GeneCards
HPCAHPCAhippocalcinSource|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
B3GALT2B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2Source|GeneCards
MAXMAXMAX proteinSource|GeneCards
HNRPA1HNRPA1heterogeneous nuclear ribonucleoprotein A1Source|GeneCards
GPS1GPS1G protein pathway suppressor 1Source|GeneCards
FLJ23311E2F8E2F transcription factor 8Source|GeneCards
KIAA0664KIAA0664KIAA0664 proteinSource|GeneCards
KIAA0672KIAA0672KIAA0672 gene productSource|GeneCards
NPHS1NPHS1nephrosis 1, congenital, Finnish type (nephrin)Source|GeneCards
INSM1INSM1insulinoma-associated 1Source|GeneCards
USP36USP36ubiquitin specific protease 36Source|GeneCards
STAT3STAT3signal transducer and activator of transcription 3 (acute-phase response factor)Source|GeneCards
C14ORF43C14ORF43chromosome 14 open reading frame 43Source|GeneCards
HOXB7HOXB7homeo box B7Source|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
WDR17WDR17WD repeat domain 17Source|GeneCards
TLP19TXNDC12thioredoxin domain containing 12 (endoplasmic reticulum)Source|GeneCards
PPP2R2BPPP2R2Bprotein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoformSource|GeneCards
KIAA0669TSC22D2TSC22 domain family, member 2Source|GeneCards
SOMGRHL3grainyhead-like 3 (Drosophila)Source|GeneCards
BTBD5BTBD5BTB (POZ) domain containing 5Source|GeneCards
KBTBD2KBTBD2kelch repeat and BTB (POZ) domain containing 2Source|GeneCards
MGC13053MGC13053hypothetical protein MGC13053Source|GeneCards
SLC12A4SLC12A4solute carrier family 12 (potassium/chloride transporters), member 4Source|GeneCards
NTN2LNTN2Lnetrin 2-like (chicken)Source|GeneCards
NPM1NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)Source|GeneCards
ADSSADSSadenylosuccinate synthaseSource|GeneCards
CDKL5CDKL5cyclin-dependent kinase-like 5Source|GeneCards
IMP-1IMP-1IGF-II mRNA-binding protein 1Source|GeneCards
TOP3ATOP3Atopoisomerase (DNA) III alphaSource|GeneCards
EPB41L3EPB41L3erythrocyte membrane protein band 4.1-like 3Source|GeneCards
GPR17GPR17G protein-coupled receptor 17Source|GeneCards
MAN2A2MAN2A2mannosidase, alpha, class 2A, member 2Source|GeneCards
TIMP3TIMP3tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)Source|GeneCards
EN1EN1engrailed homolog 1Source|GeneCards
CCDC6CCDC6coiled-coil domain containing 6Source|GeneCards
POGKPOGKpogo transposable element with KRAB domainSource|GeneCards
HOXB5HOXB5homeo box B5Source|GeneCards
C19ORF13FAM61Afamily with sequence similarity 61, member ASource|GeneCards
HDGFHDGFhepatoma-derived growth factor (high-mobility group protein 1-like)Source|GeneCards
MGC10772PRR7proline rich 7 (synaptic)Source|GeneCards
ZFP91ZFP91zinc finger protein 91 homolog (mouse)Source|GeneCards
PA2G4PA2G4proliferation-associated 2G4, 38kDaSource|GeneCards
FLJ20366FLJ20366hypothetical protein FLJ20366Source|GeneCards
NEUROD6NEUROD6neurogenic differentiation 6Source|GeneCards
IVNS1ABPIVNS1ABPinfluenza virus NS1A binding proteinSource|GeneCards
LOC389792
JMJD1AJMJD1Ajumonji domain containing 1ASource|GeneCards
USP15USP15ubiquitin specific protease 15Source|GeneCards
FLJ14904MAELmaelstrom homolog (Drosophila)Source|GeneCards
AMPD2AMPD2adenosine monophosphate deaminase 2 (isoform L)Source|GeneCards
COL2A1COL2A1collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)Source|GeneCards
DKFZP564O0463WDSOF1WD repeats and SOF1 domain containingSource|GeneCards
ACY1ACY1aminoacylase 1Source|GeneCards
TGIF2TGIF2TGFB-induced factor 2 (TALE family homeobox)Source|GeneCards
DPAGT1DPAGT1dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)Source|GeneCards
NOLC1NOLC1nucleolar and coiled-body phosphoprotein 1Source|GeneCards
TP53TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
EPB41EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)Source|GeneCards
NACANACAnascent-polypeptide-associated complex alpha polypeptideSource|GeneCards
C13ORF10C13ORF10chromosome 13 open reading frame 10Source|GeneCards
KCNQ5KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5Source|GeneCards
FGF19FGF19fibroblast growth factor 19Source|GeneCards
CAM-KIINCAMK2N2calcium/calmodulin-dependent protein kinase II inhibitor 2Source|GeneCards
KIAA1972KIAA1972KIAA1972 proteinSource|GeneCards
C19ORF2C19ORF2chromosome 19 open reading frame 2Source|GeneCards
POLR2HPOLR2Hpolymerase (RNA) II (DNA directed) polypeptide HSource|GeneCards
SLICKKCNT2potassium channel, subfamily T, member 2Source|GeneCards
SOX10SOX10SRY (sex determining region Y)-box 10Source|GeneCards
ARRDC3ARRDC3arrestin domain containing 3Source|GeneCards
ANKRD17ANKRD17ankyrin repeat domain 17Source|GeneCards
FLJ38359FLJ38359hypothetical protein FLJ38359Source|GeneCards
BACH2BACH2BTB and CNC homology 1, basic leucine zipper transcription factor 2Source|GeneCards
ATOH8ATOH8Atonal homolog 8 (Drosophila)Source|GeneCards
PRKCHPRKCHprotein kinase C, etaSource|GeneCards
LRP5LRP5low density lipoprotein receptor-related protein 5Source|GeneCards
CIRH1ACIRH1Acirrhosis, autosomal recessive 1A (cirhin)Source|GeneCards
OSMOSMoncostatin MSource|GeneCards
PSME3PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)Source|GeneCards
MASAMASAE-1 enzymeSource|GeneCards
MORF4L2MORF4L2mortality factor 4 like 2Source|GeneCards
ADAMTS17ADAMTS17a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17Source|GeneCards
SLC1A7SLC1A7solute carrier family 1 (glutamate transporter), member 7Source|GeneCards
GSH1GSH1GS homeobox 1Source|GeneCards
MTHFD1MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetaseSource|GeneCards
SMCR8SMCR8Smith-Magenis syndrome chromosome region, candidate 8Source|GeneCards
C6ORF82C6ORF82chromosome 6 open reading frame 82Source|GeneCards
CHST11CHST11carbohydrate (chondroitin 4) sulfotransferase 11Source|GeneCards
FGF14FGF14fibroblast growth factor 14Source|GeneCards
TYRO3TYRO3TYRO3 protein tyrosine kinaseSource|GeneCards
PCDHA10PCDHA10protocadherin alpha 10Source|GeneCards
CITED1CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1Source|GeneCards
C20ORF104PHF20PHD finger protein 20Source|GeneCards
PRKCGPRKCGprotein kinase C, gammaSource|GeneCards
SATB2SATB2SATB family member 2Source|GeneCards
OK/SW-CL.56TUBBTubulin, beta polypeptideSource|GeneCards
SILVSILVsilver homolog (mouse)Source|GeneCards
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)Source|GeneCards
CNNM1CNNM1cyclin M1Source|GeneCards
JMJD1CJMJD1Cjumonji domain containing 1CSource|GeneCards
RAB30RAB30RAB30, member RAS oncogene familySource|GeneCards
LOC148523LOC148523hypothetical protein BC017397Source|GeneCards
KIAA0423KIAA0423KIAA0423Source|GeneCards
RCL1RCL1RNA terminal phosphate cyclase-like 1Source|GeneCards
MAT2AMAT2Amethionine adenosyltransferase II, alphaSource|GeneCards
APLNAPLNapelinSource|GeneCards
PRDM4PRDM4PR domain containing 4Source|GeneCards
OPRD1OPRD1opioid receptor, delta 1Source|GeneCards
IGF1RIGF1Rinsulin-like growth factor 1 receptorSource|GeneCards
TIMM8ATIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast)Source|GeneCards
BCORBCORBCL6 co-repressorSource|GeneCards
PABPC4PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)Source|GeneCards
CSKCSKc-src tyrosine kinaseSource|GeneCards
CSMD3CSMD3CUB and Sushi multiple domains 3Source|GeneCards
VNN1VNN1vanin 1Source|GeneCards
MLLMLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)Source|GeneCards
LZTS2LZTS2leucine zipper, putative tumor suppressor 2Source|GeneCards
FBLFBLfibrillarinSource|GeneCards
BMP2KBMP2KBMP2 inducible kinaseSource|GeneCards
GIT1GIT1G protein-coupled receptor kinase-interactor 1Source|GeneCards
LEMD2LEMD2LEM domain containing 2Source|GeneCards
SMAD2SMAD2SMAD, mothers against DPP homolog 2 (Drosophila)Source|GeneCards
ATF7IPATF7IPactivating transcription factor 7 interacting proteinSource|GeneCards
RNF12RNF12ring finger protein 12Source|GeneCards
HOXC11HOXC11homeo box C11Source|GeneCards
ODDGJA1gap junction protein, alpha 1, 43kDa (connexin 43)Source|GeneCards
PPP1R9BPPP1R9Bprotein phosphatase 1, regulatory subunit 9B, spinophilinSource|GeneCards
BCKDHABCKDHAbranched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease)Source|GeneCards
MAP7MAP7microtubule-associated protein 7Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
FLJ10385WDR79WD repeat domain 79Source|GeneCards
SCRT2SCRT2scratch homolog 2, zinc finger protein (Drosophila)Source|GeneCards
MBNL1MBNL1muscleblind-like (Drosophila)Source|GeneCards
PPM1APPM1Aprotein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoformSource|GeneCards
SYNCRIPSYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting proteinSource|GeneCards
NR5A1NR5A1nuclear receptor subfamily 5, group A, member 1Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
HSPA4HSPA4heat shock 70kDa protein 4Source|GeneCards
KIAA1259KIAA1259hypothetical protein KIAA1259Source|GeneCards
RAB35RAB35RAB35, member RAS oncogene familySource|GeneCards
DZIP1DZIP1DAZ interacting protein 1Source|GeneCards
MASK-BP3MASK-BP3MASK-4E-BP3 alternate reading frame geneSource|GeneCards
FGF20FGF20fibroblast growth factor 20Source|GeneCards
FLJ20130FLJ20130hypothetical protein FLJ20130Source|GeneCards
DIABLODIABLOdiablo homolog (Drosophila)Source|GeneCards
PTK7PTK7PTK7 protein tyrosine kinase 7Source|GeneCards
WDR23WDR23WD repeat domain 23Source|GeneCards
EIF4BEIF4Beukaryotic translation initiation factor 4BSource|GeneCards
SGCDSGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)Source|GeneCards
FLJ23235FLJ23235hypothetical protein FLJ23235Source|GeneCards
MTVR1MTVR1Mouse Mammary Turmor Virus Receptor homolog 1Source|GeneCards
LRRC2LRRC2leucine rich repeat containing 2Source|GeneCards
EFNB1EFNB1ephrin-B1Source|GeneCards
UMPSUMPSuridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)Source|GeneCards
C19ORF4C19ORF4chromosome 19 open reading frame 4Source|GeneCards
ISGF3GISGF3Ginterferon-stimulated transcription factor 3, gamma 48kDaSource|GeneCards
SYT6SYT6synaptotagmin VISource|GeneCards
CLCN2CLCN2chloride channel 2Source|GeneCards
SEMA7ASEMA7Asema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7ASource|GeneCards
IQGAP2IQGAP2IQ motif containing GTPase activating protein 2Source|GeneCards
MAK3MAK3Mak3 homolog (S. cerevisiae)Source|GeneCards
FZD6FZD6frizzled homolog 6 (Drosophila)Source|GeneCards
ARF6ARF6ADP-ribosylation factor 6Source|GeneCards
MGC46534ATXN7L2ataxin 7-like 2Source|GeneCards
LOC90668LOC90668hypothetical protein BC008134Source|GeneCards
EPB41L4BEPB41L4Berythrocyte membrane protein band 4.1 like 4BSource|GeneCards
TNFRSF21TNFRSF21tumor necrosis factor receptor superfamily, member 21Source|GeneCards
TYRP1TYRP1tyrosinase-related protein 1Source|GeneCards
CDKN2CCDKN2Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Source|GeneCards
ENPP2ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)Source|GeneCards
RAI14RAI14retinoic acid induced 14Source|GeneCards
LEF1LEF1lymphoid enhancer-binding factor 1Source|GeneCards
IRS4IRS4insulin receptor substrate 4Source|GeneCards
HOXA7HOXA7homeo box A7Source|GeneCards
NR1D1NR1D1nuclear receptor subfamily 1, group D, member 1Source|GeneCards
NMNAT2NMNAT2nicotinamide nucleotide adenylyltransferase 2Source|GeneCards
FLJ13984FLJ13984hypothetical protein FLJ13984Source|GeneCards
EXOSC5EXOSC5exosome component 5Source|GeneCards
RASGEF1BRASGEF1BRasGEF domain family, member 1BSource|GeneCards
RNF128RNF128ring finger protein 128Source|GeneCards
FLJ41841FLJ41841FLJ41841 proteinSource|GeneCards
FLJ10081FLJ10081hypothetical protein FLJ10081Source|GeneCards
FGF6FGF6fibroblast growth factor 6Source|GeneCards

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