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Gene set: V$POU6F1_01 (C3:TFAC:0248)
Standard nameV$POU6F1_01
Systematic nameC3:TFAC:0248
Brief descriptionGenes with 3'UTR containing motif GCATAAWTTAT which matches annotation for POU6F1: POU domain, class 6, transcription factor 1
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA POU6F1 (c2)
 XX
 SY Brain-5 (c2);
Emb (c2); Brn-5 (c2).
 XX
 OS mouse, Mus musculus
 OC
eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda;
mammalia;
 OC eutheria; rodentia; myomorpha; muridae; murinae

XX
 XX
 CL C0007; POU; 3.1.2.6.1.2.
 XX
 SZ 301 AA;
32.9 kDa (m)
 XX
 XX
 SC translated from EMBL #D13801

XX
 FT 1 131 replaced by 1-20 in splice variant c7.
 FT
11 17 NAQGQVI repeat 1.
 FT 50 56 NAQGQVI repeat 2.
 FT
63 135 proline-rich region (18/73).
 FT 131 131 Lys replaced
by 131-133 (S-L-E) in variant c1.
 FT 139 213 PF00157; pou.

FT 139 213 SM00352; POU.
 FT 140 213 POU-specific domain.

FT 234 293 POU homeo domain.
 FT 234 296 SM00389; HOX.

FT 235 291 PF00046; homeobox.
 XX
 SF at least four additional
alternative splice products: POU6F1 c1, c5, c6,
 SF and c7,
the last being a testis-specific variant in which a distinct 5'-UTR

SF and thus another translation initiation region has been fused
directly to
 SF the POU domain;
 SF splice variants c3 and
c4 differ from c2 only in the 5' UTR region and thus
 SF encode
identical proteins [3];
 SF binding consensus is very similar
to Brn-3 proteins (POU4 group) [1];
 XX
 CP (E15.5-16.5:)
laminar region of forebrain cortex, mitral region of
 CP olfactory
bulb, (adult:) brain, mitral cell layer of olfactory bulb,

CP pyramidal cell layer of hippocampus, granule cell layer of
cerebellum and
 CP cortex, kidney, skeletal muscle [3] [2]

CN (adult:) gut heart, liver [3]
 XX
 FF may play a role
in specifying a subset of neurons [2]
 XX
 XX
 XX

XX
 RN [1]; RE0016787.
 RX MEDLINE; 99069412.
 RA Rhee
J. M., Gruber C. A., Brodie T. B., Trieu M., Turner E. E.

RT Highly cooperative homodimerization is a conserved property
of neural POU
 RT proteins
 RL J. Biol. Chem. 273:34196-34205
(1998).
 RN [2]; RE0008988.
 RX MEDLINE; 94192665.
 RA
Wey E., Lyons G. E., Schaefer B. W.
 RT A human POU domain
gene, mPOU, is expressed in developing brain and
 RT specific
adult tissues
 RL Eur. J. Biochem. 220:753-762 (1994).

RN [3]; RE0004419.
 RX MEDLINE; 93216691.
 RA Okamoto K.,
Wakamiya M., Noji S., Koyama E., Taniguchi S., Takemura R.,

RA Copeland N. G., Gilbert D. J., Jenkins N. A., Muramatsu M.,
Hamada H.
 RT A novel class of murine POU gene predominantly
expressed in central nervous
 RT system
 RL J. Biol. Chem.
268:7449-7457 (1993).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

244 genes, 244 accessions (Toggle view)

AccessionGeneTitleLinks
OFCC1OFCC1orofacial cleft 1 candidate 1Source|GeneCards
C10ORF11C10ORF11chromosome 10 open reading frame 11Source|GeneCards
FLJ42486FLJ42486FLJ42486 proteinSource|GeneCards
ZNF533ZNF533Zinc finger protein 533Source|GeneCards
SOX4SOX4SRY (sex determining region Y)-box 4Source|GeneCards
ODZ1ODZ1odz, odd Oz/ten-m homolog 1(Drosophila)Source|GeneCards
MEIS1MEIS1Meis1, myeloid ecotropic viral integration site 1 homolog (mouse)Source|GeneCards
C14ORF39C14ORF39chromosome 14 open reading frame 39Source|GeneCards
CDH20CDH20cadherin 20, type 2Source|GeneCards
CBLN1CBLN1cerebellin 1 precursorSource|GeneCards
NTF3NTF3neurotrophin 3Source|GeneCards
HS3ST1HS3ST1heparan sulfate (glucosamine) 3-O-sulfotransferase 1Source|GeneCards
LECT1LECT1leukocyte cell derived chemotaxin 1Source|GeneCards
GNB1LGNB1Lguanine nucleotide binding protein (G protein), beta polypeptide 1-likeSource|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
FHL5FHL5four and a half LIM domains 5Source|GeneCards
MEIS2MEIS2Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)Source|GeneCards
PITX2PITX2paired-like homeodomain transcription factor 2Source|GeneCards
RTN4RTN4reticulon 4Source|GeneCards
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)Source|GeneCards
NTNG2NTNG2netrin G2Source|GeneCards
MYH8MYH8myosin, heavy polypeptide 8, skeletal muscle, perinatalSource|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
FYNFYNFYN oncogene related to SRC, FGR, YESSource|GeneCards
WWP2WWP2Nedd-4-like ubiquitin-protein ligaseSource|GeneCards
DTNADTNAdystrobrevin, alphaSource|GeneCards
STOML2STOML2stomatin (EPB72)-like 2Source|GeneCards
C20ORF10C20ORF10chromosome 20 open reading frame 10Source|GeneCards
GPR91SUCNR1succinate receptor 1Source|GeneCards
CXCL13CXCL13chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)Source|GeneCards
MGC26999FAM46Dfamily with sequence similarity 46, member DSource|GeneCards
ASCL4ASCL4class II bHLH protein ASCL4Source|GeneCards
EYA1EYA1eyes absent homolog 1 (Drosophila)Source|GeneCards
ZNF364ZNF364zinc finger protein 364Source|GeneCards
FLJ10178FLJ10178hypothetical protein FLJ10178Source|GeneCards
MGC35450MGC35450hypothetical protein MGC35450Source|GeneCards
LIPGLIPGlipase, endothelialSource|GeneCards
FLJ26184C16ORF47chromosome 16 open reading frame 47Source|GeneCards
ZFPM2ZFPM2zinc finger protein, multitype 2Source|GeneCards
TMIETMIEtransmembrane inner ear proteinSource|GeneCards
HIP1RHIP1Rhuntingtin interacting protein-1-relatedSource|GeneCards
FBXO32FBXO32F-box only protein 32Source|GeneCards
KRT10KRT10keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)Source|GeneCards
LOC92799LOC92799hypothetical protein BC007653Source|GeneCards
PCDH18PCDH18protocadherin 18Source|GeneCards
MYH4MYH4myosin, heavy polypeptide 4, skeletal muscleSource|GeneCards
NSD1NSD1nuclear receptor binding SET domain protein 1Source|GeneCards
PCDHA3PCDHA3protocadherin alpha 3Source|GeneCards
FLJ41046FLJ41046FLJ41046 proteinSource|GeneCards
KIAA1446KIAA1446brain-enriched guanylate kinase-associated proteinSource|GeneCards
ABLIM2ABLIM2actin binding LIM protein 2Source|GeneCards
NFRKBNFRKBnuclear factor related to kappa B binding proteinSource|GeneCards
FBXW7FBXW7F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)Source|GeneCards
ABLIM1ABLIM1actin binding LIM protein 1Source|GeneCards
PLAG1PLAG1pleiomorphic adenoma gene 1Source|GeneCards
LOC283439LOC283439hypothetical protein LOC283439Source|GeneCards
CUGBP2CUGBP2CUG triplet repeat, RNA binding protein 2Source|GeneCards
MGC33926MGC33926hypothetical protein MGC33926Source|GeneCards
DKFZP564J0123DKFZP564J0123nuclear protein E3-3Source|GeneCards
DKFZP434I2117FAM57Bfamily with sequence similarity 57, member BSource|GeneCards
ZA20D1ZA20D1zinc finger, A20 domain containing 1Source|GeneCards
HOXC5HOXC5homeo box C5Source|GeneCards
NR2F1NR2F1nuclear receptor subfamily 2, group F, member 1Source|GeneCards
GRCC10GRCC10likely ortholog of mouse gene rich cluster, C10 geneSource|GeneCards
REREREREarginine-glutamic acid dipeptide (RE) repeatsSource|GeneCards
PRICKLE2PRICKLE2prickle-like 2 (Drosophila)Source|GeneCards
EFEMP1EFEMP1EGF-containing fibulin-like extracellular matrix protein 1Source|GeneCards
ETV1ETV1ets variant gene 1Source|GeneCards
FLJ21125FLJ21125hypothetical protein FLJ21125Source|GeneCards
HOXC6HOXC6homeo box C6Source|GeneCards
NCAM1NCAM1neural cell adhesion molecule 1Source|GeneCards
TRAM1TRAM1Translocation associated membrane protein 1Source|GeneCards
TOB1TOB1transducer of ERBB2, 1Source|GeneCards
NEK6NEK6NIMA (never in mitosis gene a)-related kinase 6Source|GeneCards
RILPRILPrab interacting lysosomal proteinSource|GeneCards
PPP1R3APPP1R3Aprotein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle)Source|GeneCards
HOXA2HOXA2homeo box A2Source|GeneCards
FLJ23790FAM91A1family with sequence similarity 91, member A1Source|GeneCards
EPHB2EPHB2EphB2Source|GeneCards
PHOX2BPHOX2Bpaired-like homeobox 2bSource|GeneCards
SPAG9SPAG9sperm associated antigen 9Source|GeneCards
ZNFN1A2ZNFN1A2zinc finger protein, subfamily 1A, 2 (Helios)Source|GeneCards
CHES1CHES1checkpoint suppressor 1Source|GeneCards
CTSKCTSKcathepsin K (pycnodysostosis)Source|GeneCards
RTN4RL1RTN4RL1reticulon 4 receptor-like 1Source|GeneCards
DLX1DLX1distal-less homeo box 1Source|GeneCards
HGNT-IV-HHGNT-IV-HUDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homologSource|GeneCards
ETV5ETV5ets variant gene 5 (ets-related molecule)Source|GeneCards
CBX6CBX6chromobox homolog 6Source|GeneCards
NEUROG1NEUROG1neurogenin 1Source|GeneCards
PANK4PANK4pantothenate kinase 4Source|GeneCards
WARS2WARS2tryptophanyl tRNA synthetase 2 (mitochondrial)Source|GeneCards
CAMK2DCAMK2Dcalcium/calmodulin-dependent protein kinase (CaM kinase) II deltaSource|GeneCards
C5C5complement component 5Source|GeneCards
NET-5TSPAN9tetraspanin 9Source|GeneCards
KCTD15KCTD15potassium channel tetramerisation domain containing 15Source|GeneCards
RBMS1RBMS1RNA binding motif, single stranded interacting protein 1Source|GeneCards
HMGN2HMGN2high-mobility group nucleosomal binding domain 2Source|GeneCards
PNUTL2SEPT4septin 4Source|GeneCards
RHOBTB1RHOBTB1Rho-related BTB domain containing 1Source|GeneCards
DRG1DRG1developmentally regulated GTP binding protein 1Source|GeneCards
ERN1ERN1ER to nucleus signalling 1Source|GeneCards
FLJ39075FLJ39075hypothetical protein FLJ39075Source|GeneCards
SKILSKILSKI-likeSource|GeneCards
SOX5SOX5SRY (sex determining region Y)-box 5Source|GeneCards
CHCHD7CHCHD7coiled-coil-helix-coiled-coil-helix domain containing 7Source|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
PDZRN4PDZRN4PDZ domain containing RING finger 4Source|GeneCards
INPPL1INPPL1inositol polyphosphate phosphatase-like 1Source|GeneCards
LRRC15LRRC15leucine rich repeat containing 15Source|GeneCards
SYNPRSYNPRsynaptoporinSource|GeneCards
FLJ23867FLJ23867hypothetical protein FLJ23867Source|GeneCards
EPC2EPC2enhancer of polycomb homolog 2 (Drosophila)Source|GeneCards
FOXP2FOXP2forkhead box P2Source|GeneCards
GMPRGMPRguanosine monophosphate reductaseSource|GeneCards
HOXB6HOXB6homeo box B6Source|GeneCards
POU2F1POU2F1POU domain, class 2, transcription factor 1Source|GeneCards
COMMD10COMMD10COMM domain containing 10Source|GeneCards
POLR3CPOLR3Cpolymerase (RNA) III (DNA directed) polypeptide C (62kD)Source|GeneCards
PPM1LPPM1Lprotein phosphatase 1 (formerly 2C)-likeSource|GeneCards
HOXB4HOXB4homeo box B4Source|GeneCards
CDAN1CDAN1congenital dyserythropoietic anemia, type ISource|GeneCards
CCR3CCR3chemokine (C-C motif) receptor 3Source|GeneCards
EN1EN1engrailed homolog 1Source|GeneCards
ZNF238ZNF238zinc finger protein 238Source|GeneCards
TEX11TEX11testis expressed sequence 11Source|GeneCards
ZNF288ZBTB20zinc finger and BTB domain containing 20Source|GeneCards
TRAF3TRAF3TNF receptor-associated factor 3Source|GeneCards
USP11USP11ubiquitin specific protease 11Source|GeneCards
CREB5CREB5cAMP responsive element binding protein 5Source|GeneCards
KBTBD10KBTBD10kelch repeat and BTB (POZ) domain containing 10Source|GeneCards
RBM9RBM9RNA binding motif protein 9Source|GeneCards
C11ORF8C11ORF8chromosome 11 open reading frame 8Source|GeneCards
COL25A1COL25A1collagen, type XXV, alpha 1Source|GeneCards
MGC26710HORMAD2HORMA domain containing 2Source|GeneCards
EMX2EMX2empty spiracles homolog 2 (Drosophila)Source|GeneCards
CUTL1CUTL1cut-like 1, CCAAT displacement protein (Drosophila)Source|GeneCards
IL1RAPL1IL1RAPL1interleukin 1 receptor accessory protein-like 1Source|GeneCards
DTX3DTX3deltex 3 homolog (Drosophila)Source|GeneCards
CASQ2CASQ2calsequestrin 2 (cardiac muscle)Source|GeneCards
FLJ37266FLJ37266hypothetical protein FLJ37266Source|GeneCards
RORARORARAR-related orphan receptor ASource|GeneCards
KRT25DKRT25Dtype I inner root sheath specific keratin 25 irs4Source|GeneCards
ZCCHC5ZCCHC5zinc finger, CCHC domain containing 5Source|GeneCards
TAX1BP3TAX1BP3Tax1 (human T-cell leukemia virus type I) binding protein 3Source|GeneCards
STK32CSTK32Cserine/threonine kinase 32CSource|GeneCards
TFAP2BL1TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta)Source|GeneCards
FLJ42291FLJ42291FLJ42291 proteinSource|GeneCards
SP6SP6Sp6 transcription factorSource|GeneCards
ID2ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix proteinSource|GeneCards
CXXC5CXXC5CXXC finger 5Source|GeneCards
IPO4IPO4importin 4Source|GeneCards
KLRG1KLRG1killer cell lectin-like receptor subfamily G, member 1Source|GeneCards
GTF2IRD1GTF2IRD1GTF2I repeat domain containing 1Source|GeneCards
CHD2CHD2chromodomain helicase DNA binding protein 2Source|GeneCards
GRPRGRPRgastrin-releasing peptide receptorSource|GeneCards
LOC152485LOC152485hypothetical protein LOC152485Source|GeneCards
MYOGMYOGmyogenin (myogenic factor 4)Source|GeneCards
MCART1MCART1mitochondrial carrier triple repeat 1Source|GeneCards
TGIFTGIFTGFB-induced factor (TALE family homeobox)Source|GeneCards
SLC12A8SLC12A8solute carrier family 12 (potassium/chloride transporters), member 8Source|GeneCards
PRPS1L1PRPS1L1phosphoribosyl pyrophosphate synthetase 1-like 1Source|GeneCards
C14ORF116CHES1checkpoint suppressor 1Source|GeneCards
POU4F1POU4F1POU domain, class 4, transcription factor 1Source|GeneCards
SCG2SCG2Secretogranin II (chromogranin C)Source|GeneCards
FSTL1FSTL1follistatin-like 1Source|GeneCards
TMOD4TMOD4tropomodulin 4 (muscle)Source|GeneCards
PRIMA1PRIMA1proline rich membrane anchor 1Source|GeneCards
KIAA0063KIAA0063KIAA0063 gene productSource|GeneCards
MARCKSMARCKSmyristoylated alanine-rich protein kinase C substrateSource|GeneCards
STAG2STAG2stromal antigen 2Source|GeneCards
CALCRCALCRcalcitonin receptorSource|GeneCards
CACNA2D3CACNA2D3calcium channel, voltage-dependent, alpha 2/delta 3 subunitSource|GeneCards
LOC115294LOC115294similar to hypothetical protein FLJ10883Source|GeneCards
CYFIP2CYFIP2cytoplasmic FMR1 interacting protein 2Source|GeneCards
GRB7GRB7growth factor receptor-bound protein 7Source|GeneCards
TAIP-2TAIP-2TGF-beta induced apotosis protein 2Source|GeneCards
FLJ10159FLJ10159hypothetical protein FLJ10159Source|GeneCards
FGF13FGF13fibroblast growth factor 13Source|GeneCards
TLL1TLL1tolloid-like 1Source|GeneCards
IGSF4IGSF4immunoglobulin superfamily, member 4Source|GeneCards
EBI2EBI2Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)Source|GeneCards
SLC22A8SLC22A8solute carrier family 22 (organic anion transporter), member 8Source|GeneCards
PRDM13PRDM13PR domain containing 13Source|GeneCards
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2BSource|GeneCards
ICKICKintestinal cell (MAK-like) kinaseSource|GeneCards
TRIM42TRIM42tripartite motif-containing 42Source|GeneCards
FLJ13842ZMAT4zinc finger, matrin type 4Source|GeneCards
FLJ12903FLJ12903hypothetical protein FLJ12903Source|GeneCards
C9ORF39C9ORF39chromosome 9 open reading frame 39Source|GeneCards
HT017HT017HT017 proteinSource|GeneCards
LOC92162LOC92162similar to RIKEN cDNA 2600017H02Source|GeneCards
HOXA5HOXA5homeo box A5Source|GeneCards
CRHCRHcorticotropin releasing hormoneSource|GeneCards
NDPNDPNorrie disease (pseudoglioma)Source|GeneCards
FLJ46300FLJ46300FLJ46300 proteinSource|GeneCards
MGC2963MGC2963hypothetical protein MGC2963Source|GeneCards
ELAVL2ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)Source|GeneCards
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2ASource|GeneCards
MBNL1MBNL1muscleblind-like (Drosophila)Source|GeneCards
CFL2CFL2cofilin 2 (muscle)Source|GeneCards
STAUSTAUstaufen, RNA binding protein (Drosophila)Source|GeneCards
NR6A1NR6A1nuclear receptor subfamily 6, group A, member 1Source|GeneCards
HOXA11HOXA11homeo box A11Source|GeneCards
TNFSF13BTNFSF13Btumor necrosis factor (ligand) superfamily, member 13bSource|GeneCards
SEPHS1SEPHS1selenophosphate synthetase 1Source|GeneCards
FABP4FABP4fatty acid binding protein 4, adipocyteSource|GeneCards
SYT5SYT5synaptotagmin VSource|GeneCards
BAZ1ABAZ1Abromodomain adjacent to zinc finger domain, 1ASource|GeneCards
PAQR9PAQR9progestin and adipoQ receptor family member IXSource|GeneCards
PCTPPCTPphosphatidylcholine transfer proteinSource|GeneCards
MYT1MYT1myelin transcription factor 1Source|GeneCards
GRIK3GRIK3glutamate receptor, ionotropic, kainate 3Source|GeneCards
MPP6MPP6membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)Source|GeneCards
PCDH7PCDH7BH-protocadherin (brain-heart)Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
CNTN6CNTN6contactin 6Source|GeneCards
RFX3RFX3regulatory factor X, 3 (influences HLA class II expression)Source|GeneCards
HOXD4HOXD4homeo box D4Source|GeneCards
OLFML3OLFML3olfactomedin-like 3Source|GeneCards
DUSP1DUSP1dual specificity phosphatase 1Source|GeneCards
C16ORF34C16ORF34chromosome 16 open reading frame 34Source|GeneCards
FABP2FABP2fatty acid binding protein 2, intestinalSource|GeneCards
NGFBNGFBnerve growth factor, beta polypeptideSource|GeneCards
BNC2BNC2basonuclin 2Source|GeneCards
LOC221091LOC221091similar to hypothetical proteinSource|GeneCards
ADAM11ADAM11a disintegrin and metalloproteinase domain 11Source|GeneCards
OTX2OTX2orthodenticle homolog 2 (Drosophila)Source|GeneCards
HOXA7HOXA7homeo box A7Source|GeneCards
COL1A2COL1A2collagen, type I, alpha 2Source|GeneCards
PTF1APTF1Apancreas specific transcription factor, 1aSource|GeneCards
FLJ38507FLJ38507colon carcinoma related proteinSource|GeneCards
TSPAN-2TSPAN2tetraspanin 2Source|GeneCards
GPR3GPR3G protein-coupled receptor 3Source|GeneCards
PPARGC1APPARGC1Aperoxisome proliferative activated receptor, gamma, coactivator 1, alphaSource|GeneCards
DKFZP564D172DKFZP564D172hypothetical protein DKFZp564D172Source|GeneCards
PTHR1PTHR1parathyroid hormone receptor 1Source|GeneCards
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1Source|GeneCards
HOXA9HOXA9homeo box A9Source|GeneCards
GRIK4GRIK4glutamate receptor, ionotropic, kainate 4Source|GeneCards
FLJ20321CASZ1castor homolog 1, zinc finger (Drosophila)Source|GeneCards
SOX14SOX14SRY (sex determining region Y)-box 14Source|GeneCards
FEZLZNF312zinc finger protein 312Source|GeneCards
GTPBP1GTPBP1GTP binding protein 1Source|GeneCards

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