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Gene set: V$RP58_01 (C3:TFAC:0291)
Standard nameV$RP58_01
Systematic nameC3:TFAC:0291
Brief descriptionGenes with 3'UTR containing motif NNAACATCTGGA which matches annotation for ZNF238: zinc finger protein 238
CategoryC3: Motif
Sub-categoryTFAC: Transfac
Full description or Abstract

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XX
 XX
 XX
 FA RP58
 XX
 SY zinc finger protein
238; transcriptional repressor RP58; 58 KDA repressor
 SY protein;
translin-associated zinc finger protein-1.
 XX
 OS human,
Homo sapiens
 OC eukaryota; animalia; metazoa; chordata; vertebrata;
tetrapoda; mammalia;
 OC eutheria; primates
 XX
 XX

CL C0001; CH.
 XX
 SZ 522 AA; 58.3 kDa (calc)
 XX

XX
 SC translated from EMBL #AJ001388
 XX
 FT 1 115 POZ
domain [1].
 FT 14 121 PF00651; BTB.
 FT 24 121 SM00225;
BTB.
 FT 114 120 NLS (nuclear localization signal), putative
[1].
 FT 370 392 SM00355; ZnF_C2H2.
 FT 370 392 PF00096;
zf-C2H2.
 FT 372 392 zinc finger (C2H2) [1].
 FT 410 432
PF00096; zf-C2H2.
 FT 410 432 SM00355; ZnF_C2H2.
 FT 412
432 zinc finger (C2H2) [1].
 FT 438 460 PF00096; zf-C2H2.

FT 438 460 SM00355; ZnF_C2H2.
 FT 440 460 zinc finger (C2H2)
[1].
 FT 466 489 PF00096; zf-C2H2.
 FT 466 489 SM00355;
ZnF_C2H2.
 FT 468 489 zinc finger (C2H2) [1].
 XX
 SF
N-terminal region (called POZ domain, aa 1-115) highly conserved
in other
 SF members of C2H2-type zinc finger proteins: 30-40%
amino acid identity with
 SF human BCL-6 , human HIC-1,
human PLZF , human KUP ,
 SF mouse ZF-5 ,
human ZID [1]
 XX
 EX brain,,,adult;high; northern blot;
mRNA (poly-A); [1].
 EX brain,,,adult;very high; western blot;
protein; [1].
 EX colon,,,adult;detectable; northern blot;
mRNA (poly-A); [1].
 EX heart,,,adult;high; northern blot;
mRNA (poly-A); [1].
 EX heart,,,adult;low; western blot; protein;
[1].
 EX kidney (right and left),,,adult;detectable; northern
blot; mRNA (poly-A);
 EX [1].
 EX kidney (right and left),,,adult;very
low; western blot; protein; [1].
 EX liver,,,adult;detectable;
northern blot; mRNA (poly-A); [1].
 EX lung (right and left),,,adult;detectable;
northern blot; mRNA (poly-A);
 EX [1].
 EX lymphatic tissue,lymphocyte,,adult;high;
northern blot; mRNA (poly-A); [1].
 EX muscles,,,adult;high;
northern blot; mRNA (poly-A); [1].
 EX ovary (right and left),,,adult;detectable;
northern blot; mRNA (poly-A);
 EX [1].
 EX pancreas,,,adult;high;
northern blot; mRNA (poly-A); [1].
 EX placenta,,,adult;detectable;
northern blot; mRNA (poly-A); [1].
 EX prostate gland,,,adult;detectable;
northern blot; mRNA (poly-A); [1].
 EX small intestine,,,adult;detectable;
northern blot; mRNA (poly-A); [1].
 EX spleen,,,adult;low;
northern blot; mRNA (poly-A); [1].
 EX testis (right and left),,,adult;high;
northern blot; mRNA (poly-A); [1].
 EX thymus,,,adult;low;
northern blot; mRNA (poly-A); [1].
 XX
 FF repressor (mediates
transcriptional repression on sequence with multiple
 FF copies
of consensus sequence CAGATGTT) [1];
 FF interacts with translin,
a hotspot binding protein associated with
 FF chromosomal translocations
[1];
 FF subcellular location: associates in cell nucleus with
condensed chromatin
 FF (probably heterochromatin) [1];

XX
 XX
 XX
 XX
 RN [1]; RE0017569.
 RX MEDLINE;
98434584.
 RA Aoki K., Meng G., Suzuki K., Takashi T., Kameoka
Y., Nakahara K., Ishida
 RA R., Kasai M.
 RT RP58 associates
with condensed chromatin and mediates a sequence-specific

RT transcriptional repression.
 RL J. Biol. Chem. 273:26698-26704
(1998).
 XX
Publication URLna
External linksna
Keywords & MeSH headingsna
OrganismHuman,Mouse,Rat,Dog
Contributed byBroad Institute
Source platformSeq_Accession
Downloadgrp|xml|map
Genes

216 genes, 216 accessions (Toggle view)

AccessionGeneTitleLinks
PDE10APDE10Aphosphodiesterase 10ASource|GeneCards
PITX3PITX3paired-like homeodomain transcription factor 3Source|GeneCards
GRIN2DGRIN2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2DSource|GeneCards
NXPH4NXPH4neurexophilin 4Source|GeneCards
ATF3ATF3activating transcription factor 3Source|GeneCards
LOC83468LOC83468gycosyltransferaseSource|GeneCards
CASC2CASC2Cancer susceptibility candidate 2Source|GeneCards
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)Source|GeneCards
CA10CA10carbonic anhydrase XSource|GeneCards
CACNG4CACNG4calcium channel, voltage-dependent, gamma subunit 4Source|GeneCards
FGF7FGF7fibroblast growth factor 7 (keratinocyte growth factor)Source|GeneCards
NXPH3NXPH3neurexophilin 3Source|GeneCards
KERAKERAkeratocanSource|GeneCards
LMO3LMO3LIM domain only 3 (rhombotin-like 2)Source|GeneCards
COL16A1COL16A1collagen, type XVI, alpha 1Source|GeneCards
SHOX2SHOX2short stature homeobox 2Source|GeneCards
ACVR1ACVR1activin A receptor, type ISource|GeneCards
TNSTNStensinSource|GeneCards
CMKLR1CMKLR1chemokine-like receptor 1Source|GeneCards
C14ORF27CLEC14AC-type lectin domain family 14, member ASource|GeneCards
MRGPRFMRGPRFMAS-related GPR, member FSource|GeneCards
ARHGAP22ARHGAP22Rho GTPase activating protein 22Source|GeneCards
CREB3L2CREB3L2cAMP responsive element binding protein 3-like 2Source|GeneCards
UNQ564OLFML1olfactomedin-like 1Source|GeneCards
FYFYDuffy blood groupSource|GeneCards
ERGERGv-ets erythroblastosis virus E26 oncogene like (avian)Source|GeneCards
ARXARXaristaless related homeoboxSource|GeneCards
CABP7CABP7calcium binding protein 7Source|GeneCards
XKRXXKRXX Kell blood group precursor-related, X-linkedSource|GeneCards
RAB6ARAB6ARAB6A, member RAS oncogene familySource|GeneCards
TNRC5TNRC5trinucleotide repeat containing 5Source|GeneCards
HOXA3HOXA3homeo box A3Source|GeneCards
FLJ45832FLJ45832FLJ45832 proteinSource|GeneCards
SH3GLB2SH3GLB2SH3-domain GRB2-like endophilin B2Source|GeneCards
ABLIM3ABLIM3actin binding LIM protein family, member 3Source|GeneCards
EYA1EYA1eyes absent homolog 1 (Drosophila)Source|GeneCards
PODNPODNpodocanSource|GeneCards
DNAJC5BDNAJC5BDnaJ (Hsp40) homolog, subfamily C, member 5 betaSource|GeneCards
PMF1PMF1polyamine-modulated factor 1Source|GeneCards
CACNB2CACNB2calcium channel, voltage-dependent, beta 2 subunitSource|GeneCards
SLC26A7SLC26A7solute carrier family 26, member 7Source|GeneCards
KATNA1KATNA1katanin p60 (ATPase-containing) subunit A 1Source|GeneCards
HOXC12HOXC12homeo box C12Source|GeneCards
MKRN4MKRN4makorin, ring finger protein, 4Source|GeneCards
PPRC1PPRC1peroxisome proliferative activated receptor, gamma, coactivator-related 1Source|GeneCards
EDG5EDG5endothelial differentiation, sphingolipid G-protein-coupled receptor, 5Source|GeneCards
EGFL6EGFL6EGF-like-domain, multiple 6Source|GeneCards
LRRTM3LRRTM3leucine-rich repeat transmembrane neuronal 3 proteinSource|GeneCards
DHX30DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 30Source|GeneCards
SIPA1SIPA1signal-induced proliferation-associated gene 1Source|GeneCards
TRIPLRRFIP1leucine rich repeat (in FLII) interacting protein 1Source|GeneCards
RARGRARGretinoic acid receptor, gammaSource|GeneCards
P11S100A10S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))Source|GeneCards
HABP2HABP2hyaluronan binding protein 2Source|GeneCards
ANK2ANK2ankyrin 2, neuronalSource|GeneCards
C1QTNF1C1QTNF1C1q and tumor necrosis factor related protein 1Source|GeneCards
NRGNNRGNneurogranin (protein kinase C substrate, RC3)Source|GeneCards
KIF21AKIF21Akinesin family member 21ASource|GeneCards
EPHA7EPHA7EphA7Source|GeneCards
PRICKLE1PRICKLE1prickle-like 1 (Drosophila)Source|GeneCards
LOC113251LOC113251c-Mpl binding proteinSource|GeneCards
CNTN2CNTN2contactin 2 (axonal)Source|GeneCards
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2Source|GeneCards
DLX5DLX5distal-less homeo box 5Source|GeneCards
RAB11-FIP2RAB11FIP2RAB11 family interacting protein 2 (class I)Source|GeneCards
ACCN1ACCN1amiloride-sensitive cation channel 1, neuronal (degenerin)Source|GeneCards
ADAMTS10ADAMTS10a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10Source|GeneCards
MGC4655MGC4655hypothetical protein MGC4655Source|GeneCards
LTBP1LTBP1latent transforming growth factor beta binding protein 1Source|GeneCards
TAC1TAC1tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)Source|GeneCards
PCDH1PCDH1protocadherin 1 (cadherin-like 1)Source|GeneCards
SEPT3SEPT3septin 3Source|GeneCards
PHOX2BPHOX2Bpaired-like homeobox 2bSource|GeneCards
SARGC1ORF116chromosome 1 open reading frame 116Source|GeneCards
ANP32AANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member ASource|GeneCards
TP53INP2TP53INP2tumor protein p53 inducible nuclear protein 2Source|GeneCards
SORBS1SORBS1sorbin and SH3 domain containing 1Source|GeneCards
TGFB3TGFB3transforming growth factor, beta 3Source|GeneCards
TGFBR2TGFBR2transforming growth factor, beta receptor II (70/80kDa)Source|GeneCards
AKAP2AKAP2A kinase (PRKA) anchor protein 2Source|GeneCards
IGF1IGF1insulin-like growth factor 1 (somatomedin C)Source|GeneCards
GGCXGGCXgamma-glutamyl carboxylaseSource|GeneCards
TP73LTP73Ltumor protein p73-likeSource|GeneCards
ATOH7ATOH7atonal homolog 7 (Drosophila)Source|GeneCards
TFAP4TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Source|GeneCards
SPRED2SPRED2sprouty-related, EVH1 domain containing 2Source|GeneCards
B3GALT2B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2Source|GeneCards
POU3F4POU3F4POU domain, class 3, transcription factor 4Source|GeneCards
FGF10FGF10fibroblast growth factor 10Source|GeneCards
FLJ32867FLJ32867FLJ32867 proteinSource|GeneCards
GLRA1GLRA1glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)Source|GeneCards
ITGA8ITGA8integrin, alpha 8Source|GeneCards
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)Source|GeneCards
TNKS1BP1TNKS1BP1tankyrase 1 binding protein 1, 182kDaSource|GeneCards
RBMS1RBMS1RNA binding motif, single stranded interacting protein 1Source|GeneCards
COL7A1COL7A1collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)Source|GeneCards
KLF5KLF5Kruppel-like factor 5 (intestinal)Source|GeneCards
TLR7TLR7toll-like receptor 7Source|GeneCards
E2IG4LRRC54leucine rich repeat containing 54Source|GeneCards
TBPL1TBPL1TBP-like 1Source|GeneCards
ERN1ERN1ER to nucleus signalling 1Source|GeneCards
DSIPIDSIPIdelta sleep inducing peptide, immunoreactorSource|GeneCards
HOXC4HOXC4homeo box C4Source|GeneCards
PRIC285PRIC285peroxisomal proliferator-activated receptor A interacting complex 285Source|GeneCards
GFPT2GFPT2glutamine-fructose-6-phosphate transaminase 2Source|GeneCards
PRG4PRG4proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)Source|GeneCards
PCOLCEPCOLCEprocollagen C-endopeptidase enhancerSource|GeneCards
ACCN2ACCN2amiloride-sensitive cation channel 2, neuronalSource|GeneCards
DKFZP566A1524FAM49Afamily with sequence similarity 49, member ASource|GeneCards
PNMA1PNMA1paraneoplastic antigen MA1Source|GeneCards
FOXP2FOXP2forkhead box P2Source|GeneCards
LENG9LENG9leukocyte receptor cluster (LRC) member 9Source|GeneCards
TNFAIP8TNFAIP8tumor necrosis factor, alpha-induced protein 8Source|GeneCards
DAPK1DAPK1death-associated protein kinase 1Source|GeneCards
ZNF238ZNF238zinc finger protein 238Source|GeneCards
MGC50896CNIH2cornichon homolog 2 (Drosophila)Source|GeneCards
ABRABRactive BCR-related geneSource|GeneCards
AMD1AMD1adenosylmethionine decarboxylase 1Source|GeneCards
NAV1NAV1neuron navigator 1Source|GeneCards
ZFHX1BZFHX1Bzinc finger homeobox 1bSource|GeneCards
MOAP1MOAP1modulator of apoptosis 1Source|GeneCards
RAG2RAG2recombination activating gene 2Source|GeneCards
UBTFUBTFupstream binding transcription factor, RNA polymerase ISource|GeneCards
PROK2PROK2prokineticin 2Source|GeneCards
MGC27434CCDC26coiled-coil domain containing 26Source|GeneCards
FLJ43855FLJ43855similar to sodium- and chloride-dependent creatine transporterSource|GeneCards
NEUROG3NEUROG3neurogenin 3Source|GeneCards
LAKARL7ADP-ribosylation factor-like 7Source|GeneCards
TNNI3KTNNI3KTNNI3 interacting kinaseSource|GeneCards
PARK2PARK2Parkinson disease (autosomal recessive, juvenile) 2, parkinSource|GeneCards
UNQ1940UNQ1940HWKM1940Source|GeneCards
SCN2BSCN2Bsodium channel, voltage-gated, type II, betaSource|GeneCards
MPRP-1OMA1OMA1 homolog, zinc metallopeptidase (S. cerevisiae)Source|GeneCards
SEMA6DSEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6DSource|GeneCards
ANKRD12ANKRD12ankyrin repeat domain 12Source|GeneCards
BAI3BAI3brain-specific angiogenesis inhibitor 3Source|GeneCards
ATOH8ATOH8Atonal homolog 8 (Drosophila)Source|GeneCards
LRP5LRP5low density lipoprotein receptor-related protein 5Source|GeneCards
CILPCILPcartilage intermediate layer protein, nucleotide pyrophosphohydrolaseSource|GeneCards
C14ORF116CHES1checkpoint suppressor 1Source|GeneCards
HSPB7HSPB7heat shock 27kDa protein family, member 7 (cardiovascular)Source|GeneCards
POU4F1POU4F1POU domain, class 4, transcription factor 1Source|GeneCards
INHAINHAinhibin, alphaSource|GeneCards
DNAJC11DNAJC11DnaJ (Hsp40) homolog, subfamily C, member 11Source|GeneCards
MYL3MYL3myosin, light polypeptide 3, alkali; ventricular, skeletal, slowSource|GeneCards
COLEC12COLEC12collectin sub-family member 12Source|GeneCards
FMNL3FMNL3formin-like 3Source|GeneCards
CACNA2D3CACNA2D3calcium channel, voltage-dependent, alpha 2/delta 3 subunitSource|GeneCards
ATP2A2ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2Source|GeneCards
PTCH2PTCH2patched homolog 2 (Drosophila)Source|GeneCards
GFRA3GFRA3GDNF family receptor alpha 3Source|GeneCards
SRPULSRPX2sushi-repeat-containing protein, X-linked 2Source|GeneCards
A2BP1A2BP1ataxin 2-binding protein 1Source|GeneCards
TLL1TLL1tolloid-like 1Source|GeneCards
ARK5NUAK1NUAK family, SNF1-like kinase, 1Source|GeneCards
DLG3DLG3Discs, large homolog 3 (neuroendocrine-dlg, Drosophila)Source|GeneCards
ONECUT1ONECUT1one cut domain, family member 1Source|GeneCards
RIMS2RIMS2regulating synaptic membrane exocytosis 2Source|GeneCards
PACRGPACRGPARK2 co-regulatedSource|GeneCards
CDC42EP2CDC42EP2CDC42 effector protein (Rho GTPase binding) 2Source|GeneCards
ONECUT2ONECUT2one cut domain, family member 2Source|GeneCards
GAS7GAS7growth arrest-specific 7Source|GeneCards
LRRC1LRRC1leucine rich repeat containing 1Source|GeneCards
HGFHGFhepatocyte growth factor (hepapoietin A; scatter factor)Source|GeneCards
LBX1LBX1transcription factor similar to D. melanogaster homeodomain protein lady bird lateSource|GeneCards
C5ORF11C5ORF11chromosome 5 open reading frame 11Source|GeneCards
WNT2WNT2wingless-type MMTV integration site family member 2Source|GeneCards
DMDDMDdystrophin (muscular dystrophy, Duchenne and Becker types)Source|GeneCards
PPAP2BPPAP2Bphosphatidic acid phosphatase type 2BSource|GeneCards
PRKACAPRKACAProtein kinase, cAMP-dependent, catalytic, alphaSource|GeneCards
HT017HT017HT017 proteinSource|GeneCards
WNT9AWNT9Awingless-type MMTV integration site family, member 9ASource|GeneCards
CD79BCD79BCD79B antigen (immunoglobulin-associated beta)Source|GeneCards
PPP1R9BPPP1R9Bprotein phosphatase 1, regulatory subunit 9B, spinophilinSource|GeneCards
SPTBSPTBspectrin, beta, erythrocytic (includes spherocytosis, clinical type I)Source|GeneCards
RCOR2RCOR2REST corepressor 2Source|GeneCards
NTN1NTN1netrin 1Source|GeneCards
FLJ39739FLJ39739FLJ39739 proteinSource|GeneCards
DTX2DTX2deltex homolog 2 (Drosophila)Source|GeneCards
SND1SND1staphylococcal nuclease domain containing 1Source|GeneCards
PALM2PALM2paralemmin 2Source|GeneCards
TCF12TCF12transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)Source|GeneCards
NKX2-2NKX2-2NK2 transcription factor related, locus 2 (Drosophila)Source|GeneCards
COL3A1COL3A1collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)Source|GeneCards
CDH6CDH6cadherin 6, type 2, K-cadherin (fetal kidney)Source|GeneCards
WNT2BWNT2Bwingless-type MMTV integration site family, member 2BSource|GeneCards
BLMHBLMHbleomycin hydrolaseSource|GeneCards
PHLDB1PHLDB1pleckstrin homology-like domain, family B, member 1Source|GeneCards
NR4A2NR4A2nuclear receptor subfamily 4, group A, member 2Source|GeneCards
KLF13KLF13Kruppel-like factor 13Source|GeneCards
FGF20FGF20fibroblast growth factor 20Source|GeneCards
PTK7PTK7PTK7 protein tyrosine kinase 7Source|GeneCards
TNRC15TNRC15trinucleotide repeat containing 15Source|GeneCards
FGF9FGF9fibroblast growth factor 9 (glia-activating factor)Source|GeneCards
RUNX1RUNX1runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)Source|GeneCards
SLC4A1SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)Source|GeneCards
FOXP1FOXP1forkhead box P1Source|GeneCards
MGC8974LRRC42leucine rich repeat containing 42Source|GeneCards
C19ORF4C19ORF4chromosome 19 open reading frame 4Source|GeneCards
TNNI2TNNI2troponin I, skeletal, fastSource|GeneCards
ADAMTS2ADAMTS2a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2Source|GeneCards
MAGED1MAGED1melanoma antigen, family D, 1Source|GeneCards
RDH5RDH5retinol dehydrogenase 5 (11-cis and 9-cis)Source|GeneCards
PPM1BPPM1Bprotein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoformSource|GeneCards
PDGFBPDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)Source|GeneCards
MGC20470MGC20470hypothetical protein MGC20470Source|GeneCards
GPSM2GPSM2G-protein signalling modulator 2 (AGS3-like, C. elegans)Source|GeneCards
CACNA1GCACNA1Gcalcium channel, voltage-dependent, alpha 1G subunitSource|GeneCards
TRIM37TRIM37tripartite motif-containing 37Source|GeneCards
TRIAD3TRIAD3TRIAD3 proteinSource|GeneCards
SCGNSCGNsecretagogin, EF-hand calcium binding proteinSource|GeneCards
CBFA2T3CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 3Source|GeneCards
MBNL2MBNL2muscleblind-like 2 (Drosophila)Source|GeneCards
OA48-18
BTBD3BTBD3BTB (POZ) domain containing 3Source|GeneCards
FLJ21308PARP8Poly (ADP-ribose) polymerase family, member 8Source|GeneCards

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