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Gene set: atrbrcaPathway (C2:PATH:0024)
Standard nameatrbrcaPathway
Systematic nameC2:PATH:0024
Brief descriptionBRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_atrbrcaPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

22 genes, 22 accessions (Toggle view)

GeneTitleLinks
ATMataxia telangiectasia mutated (includes complementation groups A, C and D)Source|GeneCards
HUS1HUS1 checkpoint homolog (S. pombe)Source|GeneCards
FANCEFanconi anemia, complementation group ESource|GeneCards
FANCAFanconi anemia, complementation group ASource|GeneCards
NBS1NibrinSource|GeneCards
TREX1three prime repair exonuclease 1Source|GeneCards
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)Source|GeneCards
ATRataxia telangiectasia and Rad3 relatedSource|GeneCards
RAD50RAD50 homolog (S. cerevisiae)Source|GeneCards
BRCA2breast cancer 2, early onsetSource|GeneCards
RAD17RAD17 homolog (S. pombe)Source|GeneCards
FANCD2Fanconi anemia, complementation group D2Source|GeneCards
TP53tumor protein p53 (Li-Fraumeni syndrome)Source|GeneCards
RAD1RAD1 homolog (S. pombe)Source|GeneCards
FANCCFanconi anemia, complementation group CSource|GeneCards
CHEK2CHK2 checkpoint homolog (S. pombe)Source|GeneCards
FANCFFanconi anemia, complementation group FSource|GeneCards
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)Source|GeneCards
RAD9ARAD9 homolog A (S. pombe)Source|GeneCards
CHEK1CHK1 checkpoint homolog (S. pombe)Source|GeneCards
FANCGFanconi anemia, complementation group GSource|GeneCards
BRCA1breast cancer 1, early onsetSource|GeneCards