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Gene set: cdc42racPathway (C2:PATH:0045)
Standard namecdc42racPathway
Systematic nameC2:PATH:0045
Brief descriptionPI3 kinase stimulates cell migration by activating cdc42, which activates ARP2/3, which in turn promotes formation of new actin fibers.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_cdc42racPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

15 genes, 15 accessions (Toggle view)

GeneTitleLinks
ACTR3ARP3 actin-related protein 3 homolog (yeast)Source|GeneCards
WASLWiskott-Aldrich syndrome-likeSource|GeneCards
ARPC4actin related protein 2/3 complex, subunit 4, 20kDaSource|GeneCards
CDC42cell division cycle 42 (GTP binding protein, 25kDa)Source|GeneCards
ARPC3actin related protein 2/3 complex, subunit 3, 21kDaSource|GeneCards
PDGFRAplatelet-derived growth factor receptor, alpha polypeptideSource|GeneCards
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)Source|GeneCards
ARPC1Aactin related protein 2/3 complex, subunit 1A, 41kDaSource|GeneCards
ARPC2actin related protein 2/3 complex, subunit 2, 34kDaSource|GeneCards
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDaSource|GeneCards
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptideSource|GeneCards
PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
PAK1p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)Source|GeneCards
ACTR2ARP2 actin-related protein 2 homolog (yeast)Source|GeneCards