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Gene set: ctla4Pathway (C2:PATH:0062)
Standard namectla4Pathway
Systematic nameC2:PATH:0062
Brief descriptionT cell activation requires interaction with an antigen-MHC-I complex on an antigen-presenting cell (APC), as well as CD28 interaction with the APC's CD80 or 86.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_ctla4Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

21 genes, 21 accessions (Toggle view)

GeneTitleLinks
CD3ECD3E antigen, epsilon polypeptide (TiT3 complex)Source|GeneCards
TRB@T cell receptor beta locusSource|GeneCards
IL2interleukin 2Source|GeneCards
HLA-DRAmajor histocompatibility complex, class II, DR alphaSource|GeneCards
CD3ZCD3Z antigen, zeta polypeptide (TiT3 complex)Source|GeneCards
PTPN11protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)Source|GeneCards
ICOSinducible T-cell co-stimulatorSource|GeneCards
CTLA4cytotoxic T-lymphocyte-associated protein 4Source|GeneCards
GRB2growth factor receptor-bound protein 2Source|GeneCards
TRA@T cell receptor alpha locusSource|GeneCards
LCKlymphocyte-specific protein tyrosine kinaseSource|GeneCards
CD86CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)Source|GeneCards
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptideSource|GeneCards
PIK3R1phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)Source|GeneCards
CD3GCD3G antigen, gamma polypeptide (TiT3 complex)Source|GeneCards
CD80CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)Source|GeneCards
ITKIL2-inducible T-cell kinaseSource|GeneCards
CD3DCD3D antigen, delta polypeptide (TiT3 complex)Source|GeneCards
HLA-DRB1major histocompatibility complex, class II, DR beta 1Source|GeneCards
CD28CD28 antigen (Tp44)Source|GeneCards