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Gene set: il18Pathway (C2:PATH:0128)
Standard nameil18Pathway
Systematic nameC2:PATH:0128
Brief descriptionPro-inflammatory IL-18 is activated in macrophages by caspase-1 cleavage and, in conjunction with IL-12, stimulates Th1 cell differentiation.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_il18Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

6 genes, 6 accessions (Toggle view)

GeneTitleLinks
IL18interleukin 18 (interferon-gamma-inducing factor)Source|GeneCards
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)Source|GeneCards
IL2interleukin 2Source|GeneCards
CASP1caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)Source|GeneCards
IFNGinterferon, gammaSource|GeneCards
IL12Ainterleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)Source|GeneCards