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Gene set: no2il12Pathway (C2:PATH:0176)
Standard nameno2il12Pathway
Systematic nameC2:PATH:0176
Brief descriptionMacrophages activate NK cells by releasing IL-12, which induces NK cytotoxic activity in coordination with NO produced by inducible nitric oxide synthase II.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_no2il12Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

17 genes, 17 accessions (Toggle view)

GeneTitleLinks
CD3ECD3E antigen, epsilon polypeptide (TiT3 complex)Source|GeneCards
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)Source|GeneCards
STAT4signal transducer and activator of transcription 4Source|GeneCards
CD3ZCD3Z antigen, zeta polypeptide (TiT3 complex)Source|GeneCards
IFNGinterferon, gammaSource|GeneCards
NOS2Anitric oxide synthase 2A (inducible, hepatocytes)Source|GeneCards
JAK2Janus kinase 2 (a protein tyrosine kinase)Source|GeneCards
CD2CD2 antigen (p50), sheep red blood cell receptorSource|GeneCards
IL12RB1interleukin 12 receptor, beta 1Source|GeneCards
IL12RB2interleukin 12 receptor, beta 2Source|GeneCards
IL12Ainterleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)Source|GeneCards
CD4CD4 antigen (p55)Source|GeneCards
TYK2tyrosine kinase 2Source|GeneCards
CXCR3chemokine (C-X-C motif) receptor 3Source|GeneCards
CD3GCD3G antigen, gamma polypeptide (TiT3 complex)Source|GeneCards
CCR5chemokine (C-C motif) receptor 5Source|GeneCards
CD3DCD3D antigen, delta polypeptide (TiT3 complex)Source|GeneCards