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Gene set: ps1Pathway (C2:PATH:0205)
Standard nameps1Pathway
Systematic nameC2:PATH:0205
Brief descriptionPresenilin is required for gamma-secretase activity to activate Notch signaling; presenilin also inhibits beta-catenin in the Wnt/Frizzled pathway.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_ps1Pathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

14 genes, 14 accessions (Toggle view)

GeneTitleLinks
PSEN1presenilin 1 (Alzheimer disease 3)Source|GeneCards
GSK3Bglycogen synthase kinase 3 betaSource|GeneCards
TCF1Transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factorSource|GeneCards
WNT1wingless-type MMTV integration site family, member 1Source|GeneCards
BTRCbeta-transducin repeat containingSource|GeneCards
RBPSUHrecombining binding protein suppressor of hairless (Drosophila)Source|GeneCards
AXIN1axin 1Source|GeneCards
ADAM17a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)Source|GeneCards
NOTCH1Notch homolog 1, translocation-associated (Drosophila)Source|GeneCards
FZD1frizzled homolog 1 (Drosophila)Source|GeneCards
DLL1delta-like 1 (Drosophila)Source|GeneCards
DVL1dishevelled, dsh homolog 1 (Drosophila)Source|GeneCards
APCadenomatosis polyposis coliSource|GeneCards
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDaSource|GeneCards