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Gene set: tcraPathway (C2:PATH:0290)
Standard nametcraPathway
Systematic nameC2:PATH:0290
Brief descriptionThe kinases Lck and Fyn phosphorylate and activate the T cell receptor, which recognizes antigen-bound MHCII and leads to T cell activation.
CategoryC2: Curated
Sub-categoryPATH: Pathway database
Full description or Abstract
na
Publication URLna
External linksMore details for this gene set:
http://www.biocarta.com/pathfiles/h_tcraPathway.asp
Keywords & MeSH headingsna
OrganismGeneric
Contributed byBioCarta
Source platformGene_Symbol
Downloadgrp|xml|map
Genes

13 genes, 13 accessions (Toggle view)

GeneTitleLinks
TRB@T cell receptor beta locusSource|GeneCards
CD3ECD3E antigen, epsilon polypeptide (TiT3 complex)Source|GeneCards
HLA-DRAmajor histocompatibility complex, class II, DR alphaSource|GeneCards
ZAP70zeta-chain (TCR) associated protein kinase 70kDaSource|GeneCards
CD3ZCD3Z antigen, zeta polypeptide (TiT3 complex)Source|GeneCards
TRA@T cell receptor alpha locusSource|GeneCards
LCKlymphocyte-specific protein tyrosine kinaseSource|GeneCards
CD4CD4 antigen (p55)Source|GeneCards
PTPRCprotein tyrosine phosphatase, receptor type, CSource|GeneCards
CD3GCD3G antigen, gamma polypeptide (TiT3 complex)Source|GeneCards
CD3DCD3D antigen, delta polypeptide (TiT3 complex)Source|GeneCards
FYNFYN oncogene related to SRC, FGR, YESSource|GeneCards
HLA-DRB1major histocompatibility complex, class II, DR beta 1Source|GeneCards